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Leonard Shultz to Spleen

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This is a "connection" page, showing publications Leonard Shultz has written about Spleen.
Leonard Shultz
Connection Strength
1.226
Spleen
  1. Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
    View in: PubMed
    Score: 0.067
  2. Yamamoto T, Kaizu C, Kawasaki T, Hasegawa G, Umezu H, Ohashi R, Sakurada J, Jiang S, Shultz L, Naito M. Macrophage colony-stimulating factor is indispensable for repopulation and differentiation of Kupffer cells but not for splenic red pulp macrophages in osteopetrotic (op/op) mice after macrophage depletion. Cell Tissue Res. 2008 May; 332(2):245-56.
    View in: PubMed
    Score: 0.067
  3. Inoue T, Aikawa K, Tezuka H, Kada T, Shultz LD. Effect of DNA-damaging agents on isolated spleen cells and lung fibroblasts from the mouse mutant "wasted," a putative animal model for ataxia-telangiectasia. Cancer Res. 1986 Aug; 46(8):3979-82.
    View in: PubMed
    Score: 0.060
  4. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
    View in: PubMed
    Score: 0.055
  5. Hayashi S, Yamada T, Tsuneto M, Yamane T, Takahashi M, Shultz LD, Yamazaki H. Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-alpha. J Immunol. 2003 Nov 15; 171(10):5130-9.
    View in: PubMed
    Score: 0.049
  6. Shultz LD, Banuelos S, Lyons B, Samuels R, Burzenski L, Gott B, Lang P, Leif J, Appel M, Rossini A, Greiner DL. NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment. Transplantation. 2003 Oct 15; 76(7):1036-42.
    View in: PubMed
    Score: 0.049
  7. Kikuchi K, Lian ZX, He XS, Ansari AA, Ishibashi M, Miyakawa H, Shultz LD, Ikehara S, Gershwin ME. Appearance of human plasma cells following differentiation of human B cells in NOD/SCID mouse spleen. Clin Dev Immunol. 2003 Jun-Dec; 10(2-4):197-202.
    View in: PubMed
    Score: 0.048
  8. Joliat MJ, Lang PA, Lyons BL, Burzenski L, Lynes MA, Yi T, Sundberg JP, Shultz LD. Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient 'viable motheaten' mice. J Autoimmun. 2002 Mar; 18(2):105-17.
    View in: PubMed
    Score: 0.044
  9. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
    View in: PubMed
    Score: 0.038
  10. Ito S, Naito M, Kobayashi Y, Takatsuka H, Jiang S, Usuda H, Umezu H, Hasegawa G, Arakawa M, Shultz LD, Elomaa O, Tryggvason K. Roles of a macrophage receptor with collagenous structure (MARCO) in host defense and heterogeneity of splenic marginal zone macrophages. Arch Histol Cytol. 1999 Mar; 62(1):83-95.
    View in: PubMed
    Score: 0.036
  11. Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest. 1998 Jun 01; 101(11):2446-55.
    View in: PubMed
    Score: 0.034
  12. Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation. 1997 Jul 27; 64(2):329-35.
    View in: PubMed
    Score: 0.032
  13. Sundberg JP, France M, Boggess D, Sundberg BA, Jenson AB, Beamer WG, Shultz LD. Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant. Pathobiology. 1997; 65(5):271-86.
    View in: PubMed
    Score: 0.031
  14. Serreze DV, Chapman HD, Varnum DS, Hanson MS, Reifsnyder PC, Richard SD, Fleming SA, Leiter EH, Shultz LD. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. J Exp Med. 1996 Nov 01; 184(5):2049-53.
    View in: PubMed
    Score: 0.030
  15. Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
    View in: PubMed
    Score: 0.030
  16. Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science. 2015 Oct 30; 350(6260):563-567.
    View in: PubMed
    Score: 0.028
  17. Hesselton RM, Greiner DL, Mordes JP, Rajan TV, Sullivan JL, Shultz LD. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. J Infect Dis. 1995 Oct; 172(4):974-82.
    View in: PubMed
    Score: 0.028
  18. Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015 Oct 01; 195(7):3011-9.
    View in: PubMed
    Score: 0.028
  19. Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
    View in: PubMed
    Score: 0.027
  20. Takahashi K, Umeda S, Shultz LD, Hayashi S, Nishikawa S. Effects of macrophage colony-stimulating factor (M-CSF) on the development, differentiation, and maturation of marginal metallophilic macrophages and marginal zone macrophages in the spleen of osteopetrosis (op) mutant mice lacking functional M-CSF activity. J Leukoc Biol. 1994 May; 55(5):581-8.
    View in: PubMed
    Score: 0.025
  21. Robinson SN, Simmons PJ, Thomas MW, Brouard N, Javni JA, Trilok S, Shim JS, Yang H, Steiner D, Decker WK, Xing D, Shultz LD, Savoldo B, Dotti G, Bollard CM, Miller L, Champlin RE, Shpall EJ, Zweidler-McKay PA. Ex?vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2R?(null) mice. Exp Hematol. 2012 Jun; 40(6):445-56.
    View in: PubMed
    Score: 0.022
  22. Whitfield-Larry F, Young EF, Talmage G, Fudge E, Azam A, Patel S, Largay J, Byrd W, Buse J, Calikoglu AS, Shultz LD, Frelinger JA. HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/?c(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells. Diabetes. 2011 Jun; 60(6):1726-33.
    View in: PubMed
    Score: 0.021
  23. Racki WJ, Covassin L, Brehm M, Pino S, Ignotz R, Dunn R, Laning J, Graves SK, Rossini AA, Shultz LD, Greiner DL. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation. 2010 Mar 15; 89(5):527-36.
    View in: PubMed
    Score: 0.019
  24. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.018
  25. Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment. Clin Exp Immunol. 2008 Nov; 154(2):270-84.
    View in: PubMed
    Score: 0.017
  26. Evans R, Duffy TM, Shultz LD. The immunological mouse mutants nude (nu) and rhino (hrrh) generate cytotoxic effector cells following adoptive immunotherapy but fail to reject a transplanted tumor. Cancer Immunol Immunother. 1988; 26(1):35-42.
    View in: PubMed
    Score: 0.016
  27. Tezuka H, Inoue T, Noguti T, Kada T, Shultz LD. Evaluation of the mouse mutant "wasted" as an animal model for ataxia telangiectasia. I. Age-dependent and tissue-specific effects. Mutat Res. 1986 Jun; 161(1):83-90.
    View in: PubMed
    Score: 0.015
  28. Inoue T, Tezuka H, Kada T, Aikawa K, Shultz LD. The mouse mutant "wasted": an animal model for ataxia-telangiectasia. Basic Life Sci. 1986; 39:323-35.
    View in: PubMed
    Score: 0.014
  29. Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, Yoshimoto G, Watanabe T, Akashi K, Shultz LD, Harada M. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice. Blood. 2005 Sep 01; 106(5):1565-73.
    View in: PubMed
    Score: 0.014
  30. Markees TG, Pearson T, Cuthbert A, Pearson AL, Shultz LD, Leif J, Phillips NE, Mordes JP, Greiner DL, Rossini AA. Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody. Transplantation. 2004 Dec 15; 78(11):1601-8.
    View in: PubMed
    Score: 0.013
  31. Sidman CL, Marshall JD, Masiello NC, Roths JB, Shultz LD. Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice. Proc Natl Acad Sci U S A. 1984 Nov; 81(22):7199-202.
    View in: PubMed
    Score: 0.013
  32. Banuelos SJ, Shultz LD, Greiner DL, Burzenski LM, Gott B, Lyons BL, Rossini AA, Appel MC. Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. Clin Immunol. 2004 Sep; 112(3):273-83.
    View in: PubMed
    Score: 0.013
  33. Shultz LD, Coman DR, Bailey CL, Beamer WG, Sidman CL. "Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am J Pathol. 1984 Aug; 116(2):179-92.
    View in: PubMed
    Score: 0.013
  34. Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A. A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens. Eur J Immunol. 2004 Jul; 34(7):1807-16.
    View in: PubMed
    Score: 0.013
  35. Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA. Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody. Transplantation. 2004 May 15; 77(9):1341-9.
    View in: PubMed
    Score: 0.013
  36. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
    View in: PubMed
    Score: 0.012
  37. Shultz LD, Bailey CL, Coman DR. Hematopoietic stem cell function in motheaten mice. Exp Hematol. 1983 Aug; 11(7):667-80.
    View in: PubMed
    Score: 0.012
  38. Hsu HC, Shultz LD, Su X, Shi J, Yang PA, Relyea MJ, Zhang HG, Mountz JD. Mutation of the hematopoietic cell phosphatase (Hcph) gene is associated with resistance to gamma-irradiation-induced apoptosis in Src homology protein tyrosine phosphatase (SHP)-1-deficient "motheaten" mutant mice. J Immunol. 2001 Jan 15; 166(2):772-80.
    View in: PubMed
    Score: 0.010
  39. Tagaya H, Kunisada T, Yamazaki H, Yamane T, Tokuhisa T, Wagner EF, Sudo T, Shultz LD, Hayashi SI. Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice. Blood. 2000 Jun 01; 95(11):3363-70.
    View in: PubMed
    Score: 0.010
  40. Yang W, Mckenna SD, Jiao H, Tabrizi M, Lynes MA, Shultz LD, Yi T. SHP-1 deficiency in B-lineage cells is associated with heightened lyn protein expression and increased lyn kinase activity. Exp Hematol. 1998 Nov; 26(12):1126-32.
    View in: PubMed
    Score: 0.009
  41. Gordon EJ, Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody. Diabetes. 1998 Aug; 47(8):1199-206.
    View in: PubMed
    Score: 0.009
  42. Cashman JD, Lapidot T, Wang JC, Doedens M, Shultz LD, Lansdorp P, Dick JE, Eaves CJ. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood. 1997 Jun 15; 89(12):4307-16.
    View in: PubMed
    Score: 0.008
  43. Umeda S, Takahashi K, Shultz LD, Naito M, Takagi K. Effects of macrophage colony-stimulating factor on macrophages and their related cell populations in the osteopetrosis mouse defective in production of functional macrophage colony-stimulating factor protein. Am J Pathol. 1996 Aug; 149(2):559-74.
    View in: PubMed
    Score: 0.007
  44. Shultz LD, Green MC. Motheaten, an immunodeficient mutant of the mouse. II. Depressed immune competence and elevated serum immunoglobulins. J Immunol. 1976 Apr; 116(4):936-43.
    View in: PubMed
    Score: 0.007
  45. Blazar BR, Brennan CA, Broxmeyer HE, Shultz LD, Vallera DA. Transgenic mice expressing either bovine growth hormone (bGH) or human GH releasing hormone (hGRH) have increased splenic progenitor cell colony formation and DNA synthesis in vitro and in vivo. Exp Hematol. 1995 Dec; 23(13):1397-406.
    View in: PubMed
    Score: 0.007
  46. Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
    View in: PubMed
    Score: 0.007
  47. Beamer WG, Pelsue SC, Shultz LD, Sundberg JP, Barker JE. The flaky skin (fsn) mutation in mice: map location and description of the anemia. Blood. 1995 Oct 15; 86(8):3220-6.
    View in: PubMed
    Score: 0.007
  48. Green MC, Shultz LD. Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology. J Hered. 1975 Sep-Oct; 66(5):250-8.
    View in: PubMed
    Score: 0.007
  49. Rajan TV, Shultz LD, Yates J, Greiner DL. B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. J Parasitol. 1995 Jun; 81(3):490-3.
    View in: PubMed
    Score: 0.007
  50. Rohane PW, Shimada A, Kim DT, Edwards CT, Charlton B, Shultz LD, Fathman CG. Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice. Diabetes. 1995 May; 44(5):550-4.
    View in: PubMed
    Score: 0.007
  51. Rajan TV, Nelson FK, Killeen N, Shultz LD, Yates JA, Bailis JM, Littman DR, Greiner DL. CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. Exp Parasitol. 1994 Jun; 78(4):352-60.
    View in: PubMed
    Score: 0.006
  52. Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
    View in: PubMed
    Score: 0.006
  53. Kapasi ZF, Kosco-Vilbois MH, Shultz LD, Tew JG, Szakal AK. Cellular origin of follicular dendritic cells. Adv Exp Med Biol. 1994; 355:231-5.
    View in: PubMed
    Score: 0.006
  54. Christianson SW, Shultz LD, Leiter EH. Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors. Diabetes. 1993 Jan; 42(1):44-55.
    View in: PubMed
    Score: 0.006
  55. Rajan TV, Shultz LD, Greiner DL. Lack of peripherally induced tolerance to established skin allografts in immunologically reconstituted scid mice. Dev Immunol. 1992; 3(1):45-50.
    View in: PubMed
    Score: 0.005
  56. Ohara A, Anklesaria P, Shultz L, Greenberger JS. Isolation of permanent clonal bone marrow stromal cell lines derived from "viable moth-eaten" and "severe combined immunodeficiency" mutant mice. Int J Cell Cloning. 1992 Jan; 10(1):33-46.
    View in: PubMed
    Score: 0.005
  57. Nelson FK, Greiner DL, Shultz LD, Rajan TV. The immunodeficient scid mouse as a model for human lymphatic filariasis. J Exp Med. 1991 Mar 01; 173(3):659-63.
    View in: PubMed
    Score: 0.005
  58. Kolber DL, Shultz LD, Rothstein TL. Phorbol ester responsiveness of murine Ly-1-lineage B cells from normal and viable motheaten mutant mice. Eur J Immunol. 1991 Mar; 21(3):721-9.
    View in: PubMed
    Score: 0.005
  59. Sidman CL, Shultz LD, Hardy RR, Hayakawa K, Herzenberg LA. Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice. Science. 1986 Jun 13; 232(4756):1423-5.
    View in: PubMed
    Score: 0.004
  60. Sidman CL, Marshall JD, Shultz LD, Gray PW, Johnson HM. Gamma-interferon is one of several direct B cell-maturing lymphokines. Nature. 1984 Jun 28-Jul 4; 309(5971):801-4.
    View in: PubMed
    Score: 0.003
  61. Johnson DA, Shultz LD, Bedigian HG. Immunodeficiency and reticulum cell sarcoma in mice segregating for HRS/J and SJL/J genes. Leuk Res. 1982; 6(5):711-20.
    View in: PubMed
    Score: 0.003
  62. Sidman CL, Shultz LD, Unanue ER. The mouse mutant "motheaten". I. Development of lymphocyte populations. J Immunol. 1978 Dec; 121(6):2392-8.
    View in: PubMed
    Score: 0.002
  63. Sidman CL, Shultz LD, Unanue ER. The mouse mutant "motheaten." II. Functional studies of the immune system. J Immunol. 1978 Dec; 121(6):2399-404.
    View in: PubMed
    Score: 0.002
  64. Green MC, Shultz LD, Nedzi LA. Abnormal nuclear morphology of leukocytes in the mouse mutant ichthyosis. Transplantation. 1975 Aug; 20(2):172-5.
    View in: PubMed
    Score: 0.002
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