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Michael Czech to Humans

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This is a "connection" page, showing publications Michael Czech has written about Humans.
Michael Czech
Connection Strength
0.743
Humans
  1. Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrison B, Rothstein JD, Khvorova A, Czech MP. Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis. Elife. 2024 Apr 02; 12.
    View in: PubMed
    Score: 0.033
  2. Tsagkaraki E, Guilherme A, Nicoloro SM, Kelly M, Lifshitz LM, Wang H, Min K, Rowland LA, Santos KB, Wetoska N, Friedline RH, Maitland SA, Chen M, Weinstein LS, Wolfe SA, Kim JK, Czech MP. Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming. Mol Metab. 2023 10; 76:101780.
    View in: PubMed
    Score: 0.031
  3. Guilherme A, Rowland LA, Wang H, Czech MP. The adipocyte supersystem of insulin and cAMP signaling. Trends Cell Biol. 2023 04; 33(4):340-354.
    View in: PubMed
    Score: 0.030
  4. Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. Nat Commun. 2021 Nov 26; 12(1):6931.
    View in: PubMed
    Score: 0.028
  5. Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020 04; 34:27-42.
    View in: PubMed
    Score: 0.025
  6. Fitzgibbons TP, Lee N, Tran KV, Nicoloro S, Kelly M, Tam SK, Czech MP. Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat. JCI Insight. 2019 10 17; 4(20).
    View in: PubMed
    Score: 0.024
  7. Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019 04; 15(4):207-225.
    View in: PubMed
    Score: 0.023
  8. Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP. CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure. J Biol Chem. 2018 11 02; 293(44):17291-17305.
    View in: PubMed
    Score: 0.022
  9. Czech MP. Macrophages dispose of catecholamines in adipose tissue. Nat Med. 2017 11 07; 23(11):1255-1257.
    View in: PubMed
    Score: 0.021
  10. Czech MP. Insulin action and resistance in obesity and type 2 diabetes. Nat Med. 2017 Jul 11; 23(7):804-814.
    View in: PubMed
    Score: 0.021
  11. Roth Flach RJ, Guo CA, Danai LV, Yawe JC, Gujja S, Edwards YJ, Czech MP. Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function. Mol Cell Biol. 2016 06 15; 36(12):1740-9.
    View in: PubMed
    Score: 0.019
  12. Virbasius JV, Czech MP. Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases. Trends Endocrinol Metab. 2016 07; 27(7):484-492.
    View in: PubMed
    Score: 0.019
  13. Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016 Feb 16; 7:10686.
    View in: PubMed
    Score: 0.019
  14. Cohen JL, Shen Y, Aouadi M, Vangala P, Tencerova M, Amano SU, Nicoloro SM, Yawe JC, Czech MP. Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA. Mol Pharm. 2016 Mar 07; 13(3):964-978.
    View in: PubMed
    Score: 0.019
  15. Fitzgibbons TP, Czech MP. Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance. J Mol Med (Berl). 2016 Mar; 94(3):267-75.
    View in: PubMed
    Score: 0.019
  16. Roth Flach RJ, Czech MP. NETs and traps delay wound healing in diabetes. Trends Endocrinol Metab. 2015 Sep; 26(9):451-2.
    View in: PubMed
    Score: 0.018
  17. Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. FASEB J. 2015 Jul; 29(7):2959-69.
    View in: PubMed
    Score: 0.018
  18. Negrin KA, Roth Flach RJ, DiStefano MT, Matevossian A, Friedline RH, Jung D, Kim JK, Czech MP. IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis. PLoS One. 2014; 9(9):e107265.
    View in: PubMed
    Score: 0.017
  19. Fitzgibbons TP, Czech MP. Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations. J Am Heart Assoc. 2014 Mar 04; 3(2):e000582.
    View in: PubMed
    Score: 0.016
  20. Czech MP. Obesity Notches up fatty liver. Nat Med. 2013 Aug; 19(8):969-71.
    View in: PubMed
    Score: 0.016
  21. Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 2013 May; 56(5):949-64.
    View in: PubMed
    Score: 0.015
  22. Roth Flach RJ, Matevossian A, Akie TE, Negrin KA, Paul MT, Czech MP. ?3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation. J Biol Chem. 2013 Jan 25; 288(4):2882-92.
    View in: PubMed
    Score: 0.015
  23. Corvera S, Czech MP. Tensions rise and blood flows over dysfunctional fat. Circulation. 2011 Jul 05; 124(1):13-6.
    View in: PubMed
    Score: 0.014
  24. Czech MP, Aouadi M, Tesz GJ. RNAi-based therapeutic strategies for metabolic disease. Nat Rev Endocrinol. 2011 Apr 19; 7(8):473-84.
    View in: PubMed
    Score: 0.013
  25. Christianson JL, Boutet E, Puri V, Chawla A, Czech MP. Identification of the lipid droplet targeting domain of the Cidea protein. J Lipid Res. 2010 Dec; 51(12):3455-62.
    View in: PubMed
    Score: 0.013
  26. Zhou QL, Jiang ZY, Mabardy AS, Del Campo CM, Lambright DG, Holik J, Fogarty KE, Straubhaar J, Nicoloro S, Chawla A, Czech MP. A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes. J Biol Chem. 2010 Sep 03; 285(36):27581-9.
    View in: PubMed
    Score: 0.013
  27. Hardy OT, Perugini RA, Nicoloro SM, Gallagher-Dorval K, Puri V, Straubhaar J, Czech MP. Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity. Surg Obes Relat Dis. 2011 Jan-Feb; 7(1):60-7.
    View in: PubMed
    Score: 0.013
  28. Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, Chawla A, Chouinard M, Lin C, Burkart A, Corvera S, Perugini RA, Czech MP. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7833-8.
    View in: PubMed
    Score: 0.011
  29. Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol. 2008 May; 9(5):367-77.
    View in: PubMed
    Score: 0.011
  30. Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP. A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol. 2008 Jul; 28(13):4215-26.
    View in: PubMed
    Score: 0.011
  31. Huang S, Czech MP. The GLUT4 glucose transporter. Cell Metab. 2007 Apr; 5(4):237-52.
    View in: PubMed
    Score: 0.010
  32. Puri V, Chakladar A, Virbasius JV, Konda S, Powelka AM, Chouinard M, Hagan GN, Perugini R, Czech MP. RNAi-based gene silencing in primary mouse and human adipose tissues. J Lipid Res. 2007 Feb; 48(2):465-71.
    View in: PubMed
    Score: 0.010
  33. Czech MP. ARNT misbehavin' in diabetic beta cells. Nat Med. 2006 Jan; 12(1):39-40.
    View in: PubMed
    Score: 0.009
  34. Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells. J Biol Chem. 2005 Jun 03; 280(22):21622-8.
    View in: PubMed
    Score: 0.009
  35. Valeros J, Jerome M, Tseyang T, Vo P, Do T, Fajardo Palomino D, Grotehans N, Kunala M, Jerrett AE, Hathiramani NR, Mireku M, Magesh RY, Yenilmez B, Rosen PC, Mann JL, Myers JW, Kunchok T, Manning TL, Boercker LN, Carr PE, Munim MB, Lewis CA, Sabatini DM, Kelly M, Xie J, Czech MP, Gao G, Shepherd JN, Walker AK, Kim H, Watson EV, Spinelli JB. Rhodoquinone carries electrons in the mammalian electron transport chain. Cell. 2025 Feb 20; 188(4):1084-1099.e27.
    View in: PubMed
    Score: 0.009
  36. Mello CC, Czech MP. Micromanaging insulin secretion. Nat Med. 2004 Dec; 10(12):1297-8.
    View in: PubMed
    Score: 0.009
  37. Guilherme A, Soriano NA, Furcinitti PS, Czech MP. Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. J Biol Chem. 2004 Sep 17; 279(38):40062-75.
    View in: PubMed
    Score: 0.008
  38. Guilherme A, Soriano NA, Bose S, Holik J, Bose A, Pomerleau DP, Furcinitti P, Leszyk J, Corvera S, Czech MP. EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. J Biol Chem. 2004 Mar 12; 279(11):10593-605.
    View in: PubMed
    Score: 0.008
  39. Jiang ZY, Zhou QL, Coleman KA, Chouinard M, Boese Q, Czech MP. Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7569-74.
    View in: PubMed
    Score: 0.008
  40. Czech MP. Dynamics of phosphoinositides in membrane retrieval and insertion. Annu Rev Physiol. 2003; 65:791-815.
    View in: PubMed
    Score: 0.007
  41. Czech MP. Fat targets for insulin signaling. Mol Cell. 2002 Apr; 9(4):695-6.
    View in: PubMed
    Score: 0.007
  42. Jiang ZY, Chawla A, Bose A, Way M, Czech MP. A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP/Arp2/3/F-actin required for GLUT4 glucose transporter recycling. J Biol Chem. 2002 Jan 04; 277(1):509-15.
    View in: PubMed
    Score: 0.007
  43. Helderman RC, Whitney DG, Duta-Mare M, Akhmetshina A, Vujic N, Jayapalan S, Nyman JS, Misra BB, Rosen CJ, Czech MP, Kratky D, Rendina-Ruedy E. Loss of function of lysosomal acid lipase (LAL) profoundly impacts osteoblastogenesis and increases fracture risk in humans. Bone. 2021 07; 148:115946.
    View in: PubMed
    Score: 0.007
  44. Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, Saltiel AR, Corkey BE, Atkinson MA. Voices: Insulin and beyond. Cell Metab. 2021 04 06; 33(4):692-699.
    View in: PubMed
    Score: 0.007
  45. Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Bl?her M, Czech MP, Tabas I. Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 03 29; 555(7698):673-677.
    View in: PubMed
    Score: 0.005
  46. Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD. Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia. Cardiovasc Diabetol. 2017 07 07; 16(1):87.
    View in: PubMed
    Score: 0.005
  47. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li JL, Guilherme A, Guntur K, Czech MP, Collins S. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016 05 02; 126(5):1704-16.
    View in: PubMed
    Score: 0.005
  48. Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE. Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. Nat Commun. 2014 Mar 19; 5:3485.
    View in: PubMed
    Score: 0.004
  49. Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metab. 2014 Jan 07; 19(1):162-171.
    View in: PubMed
    Score: 0.004
  50. Jourdan T, Godlewski G, Cinar R, Bertola A, Szanda G, Liu J, Tam J, Han T, Mukhopadhyay B, Skarulis MC, Ju C, Aouadi M, Czech MP, Kunos G. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. Nat Med. 2013 Sep; 19(9):1132-40.
    View in: PubMed
    Score: 0.004
  51. Sartorius T, Staiger H, Ketterer C, Heni M, Machicao F, Guilherme A, Grallert H, Schulze MB, Boeing H, Stefan N, Fritsche A, Czech MP, H?ring HU. Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans. PLoS One. 2012; 7(10):e47647.
    View in: PubMed
    Score: 0.004
  52. Hardy OT, Czech MP, Corvera S. What causes the insulin resistance underlying obesity? Curr Opin Endocrinol Diabetes Obes. 2012 Apr; 19(2):81-7.
    View in: PubMed
    Score: 0.004
  53. Young JL, Mora A, Cerny A, Czech MP, Woda B, Kurt-Jones EA, Finberg RW, Corvera S. CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone. PLoS One. 2012; 7(1):e29688.
    View in: PubMed
    Score: 0.004
  54. Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8.
    View in: PubMed
    Score: 0.003
  55. Gealekman O, Guseva N, Hartigan C, Apotheker S, Gorgoglione M, Gurav K, Tran KV, Straubhaar J, Nicoloro S, Czech MP, Thompson M, Perugini RA, Corvera S. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity. Circulation. 2011 Jan 18; 123(2):186-94.
    View in: PubMed
    Score: 0.003
  56. Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, Dash S, Hyden CS, Bottomley W, Vigouroux C, Magr? J, Raymond-Barker P, Murgatroyd PR, Chawla A, Skepper JN, Chatterjee VK, Suliman S, Patch AM, Agarwal AK, Garg A, Barroso I, Cinti S, Czech MP, Argente J, O'Rahilly S, Savage DB. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med. 2009 Aug; 1(5):280-7.
    View in: PubMed
    Score: 0.003
  57. Marchand P, Antoine M, Le Baut G, Czech M, Baasner S, G?nther E. Synthesis and structure-activity relationships of N-aryl(indol-3-yl)glyoxamides as antitumor agents. Bioorg Med Chem. 2009 Sep 15; 17(18):6715-27.
    View in: PubMed
    Score: 0.003
  58. Antoine M, Marchand P, Le Baut G, Czech M, Baasner S, Gunther E. Side chain modifications of (indol-3-yl)glyoxamides as antitumor agents. J Enzyme Inhib Med Chem. 2008 Oct; 23(5):686-95.
    View in: PubMed
    Score: 0.003
  59. Saito T, Jones CC, Huang S, Czech MP, Pilch PF. The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation. J Biol Chem. 2007 Nov 02; 282(44):32280-7.
    View in: PubMed
    Score: 0.003
  60. Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes. J Biol Chem. 2005 Jun 10; 280(23):22523-9.
    View in: PubMed
    Score: 0.002
  61. Cronin TC, DiNitto JP, Czech MP, Lambright DG. Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains. EMBO J. 2004 Oct 01; 23(19):3711-20.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.