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Michael Czech to Animals

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This is a "connection" page, showing publications Michael Czech has written about Animals.
Michael Czech
Connection Strength
2.389
Animals
  1. Min K, Yenilmez B, Kelly M, Echeverria D, Elleby M, Lifshitz LM, Raymond N, Tsagkaraki E, Harney SM, DiMarzio C, Wang H, McHugh N, Bramato B, Morrison B, Rothstein JD, Khvorova A, Czech MP. Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis. Elife. 2024 Apr 02; 12.
    View in: PubMed
    Score: 0.064
  2. Tsagkaraki E, Guilherme A, Nicoloro SM, Kelly M, Lifshitz LM, Wang H, Min K, Rowland LA, Santos KB, Wetoska N, Friedline RH, Maitland SA, Chen M, Weinstein LS, Wolfe SA, Kim JK, Czech MP. Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming. Mol Metab. 2023 10; 76:101780.
    View in: PubMed
    Score: 0.061
  3. Guilherme A, Rowland LA, Wetoska N, Tsagkaraki E, Santos KB, Bedard AH, Henriques F, Kelly M, Munroe S, Pedersen DJ, Ilkayeva OR, Koves TR, Tauer L, Pan M, Han X, Kim JK, Newgard CB, Muoio DM, Czech MP. Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program. Cell Rep. 2023 05 30; 42(5):112488.
    View in: PubMed
    Score: 0.061
  4. Yenilmez B, Kelly M, Zhang GF, Wetoska N, Ilkayeva OR, Min K, Rowland L, DiMarzio C, He W, Raymond N, Lifshitz L, Pan M, Han X, Xie J, Friedline RH, Kim JK, Gao G, Herman MA, Newgard CB, Czech MP. Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. J Biol Chem. 2022 10; 298(10):102401.
    View in: PubMed
    Score: 0.058
  5. Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. Nat Commun. 2021 Nov 26; 12(1):6931.
    View in: PubMed
    Score: 0.055
  6. Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP. An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis. Mol Ther. 2022 03 02; 30(3):1329-1342.
    View in: PubMed
    Score: 0.055
  7. Henriques F, Bedard AH, Guilherme A, Kelly M, Chi J, Zhang P, Lifshitz LM, Bellv? K, Rowland LA, Yenilmez B, Kumar S, Wang Y, Luban J, Weinstein LS, Lin JD, Cohen P, Czech MP. Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020 08 04; 32(5):107998.
    View in: PubMed
    Score: 0.050
  8. Guilherme A, Yenilmez B, Bedard AH, Henriques F, Liu D, Lee A, Goldstein L, Kelly M, Nicoloro SM, Chen M, Weinstein L, Collins S, Czech MP. Control of Adipocyte Thermogenesis and Lipogenesis through ?3-Adrenergic and Thyroid Hormone Signal Integration. Cell Rep. 2020 05 05; 31(5):107598.
    View in: PubMed
    Score: 0.049
  9. Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020 04; 34:27-42.
    View in: PubMed
    Score: 0.048
  10. Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019 04; 15(4):207-225.
    View in: PubMed
    Score: 0.046
  11. Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP. CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure. J Biol Chem. 2018 11 02; 293(44):17291-17305.
    View in: PubMed
    Score: 0.044
  12. Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis. Mol Metab. 2018 10; 16:116-125.
    View in: PubMed
    Score: 0.043
  13. Roth Flach RJ, DiStefano MT, Danai LV, Senol-Cosar O, Yawe JC, Kelly M, Garcia Menendez L, Czech MP. Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2017 09 01; 313(3):E303-E313.
    View in: PubMed
    Score: 0.040
  14. Guilherme A, Pedersen DJ, Henchey E, Henriques FS, Danai LV, Shen Y, Yenilmez B, Jung D, Kim JK, Lodhi IJ, Semenkovich CF, Czech MP. Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming. Mol Metab. 2017 08; 6(8):781-796.
    View in: PubMed
    Score: 0.040
  15. DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP. Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance. Mol Metab. 2016 12; 5(12):1149-1161.
    View in: PubMed
    Score: 0.038
  16. Roth Flach RJ, Guo CA, Danai LV, Yawe JC, Gujja S, Edwards YJ, Czech MP. Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function. Mol Cell Biol. 2016 06 15; 36(12):1740-9.
    View in: PubMed
    Score: 0.037
  17. Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP. Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia. J Biol Chem. 2016 07 29; 291(31):16221-30.
    View in: PubMed
    Score: 0.037
  18. Virbasius JV, Czech MP. Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases. Trends Endocrinol Metab. 2016 07; 27(7):484-492.
    View in: PubMed
    Score: 0.037
  19. Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016 Feb 16; 7:10686.
    View in: PubMed
    Score: 0.037
  20. Cohen JL, Shen Y, Aouadi M, Vangala P, Tencerova M, Amano SU, Nicoloro SM, Yawe JC, Czech MP. Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA. Mol Pharm. 2016 Mar 07; 13(3):964-978.
    View in: PubMed
    Score: 0.037
  21. Fitzgibbons TP, Czech MP. Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance. J Mol Med (Berl). 2016 Mar; 94(3):267-75.
    View in: PubMed
    Score: 0.037
  22. Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, Czech MP. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nat Commun. 2015 Dec 21; 6:8995.
    View in: PubMed
    Score: 0.036
  23. Danai LV, Flach RJ, Virbasius JV, Menendez LG, Jung DY, Kim JH, Kim JK, Czech MP. Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues. Mol Cell Biol. 2015 Jul; 35(13):2356-65.
    View in: PubMed
    Score: 0.035
  24. DiStefano MT, Danai LV, Roth Flach RJ, Chawla A, Pedersen DJ, Guilherme A, Czech MP. The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis. J Biol Chem. 2015 Jun 12; 290(24):15175-84.
    View in: PubMed
    Score: 0.035
  25. Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. FASEB J. 2015 Jul; 29(7):2959-69.
    View in: PubMed
    Score: 0.034
  26. Negrin KA, Roth Flach RJ, DiStefano MT, Matevossian A, Friedline RH, Jung D, Kim JK, Czech MP. IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis. PLoS One. 2014; 9(9):e107265.
    View in: PubMed
    Score: 0.033
  27. Aouadi M, Vangala P, Yawe JC, Tencerova M, Nicoloro SM, Cohen JL, Shen Y, Czech MP. Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance. Am J Physiol Endocrinol Metab. 2014 Aug 15; 307(4):E374-83.
    View in: PubMed
    Score: 0.033
  28. Fitzgibbons TP, Czech MP. Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations. J Am Heart Assoc. 2014 Mar 04; 3(2):e000582.
    View in: PubMed
    Score: 0.032
  29. Danai LV, Guilherme A, Guntur KV, Straubhaar J, Nicoloro SM, Czech MP. Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling. J Lipid Res. 2013 Oct; 54(10):2697-707.
    View in: PubMed
    Score: 0.031
  30. Czech MP. Obesity Notches up fatty liver. Nat Med. 2013 Aug; 19(8):969-71.
    View in: PubMed
    Score: 0.031
  31. Aouadi M, Tencerova M, Vangala P, Yawe JC, Nicoloro SM, Amano SU, Cohen JL, Czech MP. Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8278-83.
    View in: PubMed
    Score: 0.030
  32. Guo CA, Kogan S, Amano SU, Wang M, Dagdeviren S, Friedline RH, Aouadi M, Kim JK, Czech MP. CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance. Am J Physiol Endocrinol Metab. 2013 May 01; 304(9):E951-63.
    View in: PubMed
    Score: 0.030
  33. Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 2013 May; 56(5):949-64.
    View in: PubMed
    Score: 0.030
  34. Roth Flach RJ, Matevossian A, Akie TE, Negrin KA, Paul MT, Czech MP. ?3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation. J Biol Chem. 2013 Jan 25; 288(4):2882-92.
    View in: PubMed
    Score: 0.029
  35. Wang M, Amano SU, Flach RJ, Chawla A, Aouadi M, Czech MP. Identification of Map4k4 as a novel suppressor of skeletal muscle differentiation. Mol Cell Biol. 2013 Feb; 33(4):678-87.
    View in: PubMed
    Score: 0.029
  36. Fitzgibbons TP, Kogan S, Aouadi M, Hendricks GM, Straubhaar J, Czech MP. Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1425-37.
    View in: PubMed
    Score: 0.027
  37. Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ, Soto E, Ostroff GR, Czech MP. Glucan particles for selective delivery of siRNA to phagocytic cells in mice. Biochem J. 2011 Jun 01; 436(2):351-62.
    View in: PubMed
    Score: 0.026
  38. Czech MP, Aouadi M, Tesz GJ. RNAi-based therapeutic strategies for metabolic disease. Nat Rev Endocrinol. 2011 Apr 19; 7(8):473-84.
    View in: PubMed
    Score: 0.026
  39. Ranjit S, Boutet E, Gandhi P, Prot M, Tamori Y, Chawla A, Greenberg AS, Puri V, Czech MP. Regulation of fat specific protein 27 by isoproterenol and TNF-a to control lipolysis in murine adipocytes. J Lipid Res. 2011 Feb; 52(2):221-36.
    View in: PubMed
    Score: 0.026
  40. Christianson JL, Boutet E, Puri V, Chawla A, Czech MP. Identification of the lipid droplet targeting domain of the Cidea protein. J Lipid Res. 2010 Dec; 51(12):3455-62.
    View in: PubMed
    Score: 0.025
  41. Zhou QL, Jiang ZY, Mabardy AS, Del Campo CM, Lambright DG, Holik J, Fogarty KE, Straubhaar J, Nicoloro S, Chawla A, Czech MP. A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes. J Biol Chem. 2010 Sep 03; 285(36):27581-9.
    View in: PubMed
    Score: 0.025
  42. Guntur KV, Guilherme A, Xue L, Chawla A, Czech MP. Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) gamma protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in cultured adipocytes. J Biol Chem. 2010 Feb 26; 285(9):6595-603.
    View in: PubMed
    Score: 0.024
  43. Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature. 2009 Apr 30; 458(7242):1180-4.
    View in: PubMed
    Score: 0.023
  44. Guilherme A, Tesz GJ, Guntur KVP, Czech MP. Tumor necrosis factor-alpha induces caspase-mediated cleavage of peroxisome proliferator-activated receptor gamma in adipocytes. J Biol Chem. 2009 Jun 19; 284(25):17082-17091.
    View in: PubMed
    Score: 0.023
  45. Puri V, Czech MP. Lipid droplets: FSP27 knockout enhances their sizzle. J Clin Invest. 2008 Aug; 118(8):2693-6.
    View in: PubMed
    Score: 0.022
  46. Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, Chawla A, Chouinard M, Lin C, Burkart A, Corvera S, Perugini RA, Czech MP. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7833-8.
    View in: PubMed
    Score: 0.021
  47. Zhou QL, Jiang ZY, Holik J, Chawla A, Hagan GN, Leszyk J, Czech MP. Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes. Biochem J. 2008 May 01; 411(3):647-55.
    View in: PubMed
    Score: 0.021
  48. Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol. 2008 May; 9(5):367-77.
    View in: PubMed
    Score: 0.021
  49. Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP. A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol. 2008 Jul; 28(13):4215-26.
    View in: PubMed
    Score: 0.021
  50. Christianson JL, Nicoloro S, Straubhaar J, Czech MP. Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor gamma expression and adipogenesis in cultured 3T3-L1 cells. J Biol Chem. 2008 Feb 01; 283(5):2906-16.
    View in: PubMed
    Score: 0.021
  51. Puri V, Konda S, Ranjit S, Aouadi M, Chawla A, Chouinard M, Chakladar A, Czech MP. Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J Biol Chem. 2007 Nov 23; 282(47):34213-8.
    View in: PubMed
    Score: 0.020
  52. Tesz GJ, Guilherme A, Guntur KV, Hubbard AC, Tang X, Chawla A, Czech MP. Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. J Biol Chem. 2007 Jul 06; 282(27):19302-12.
    View in: PubMed
    Score: 0.020
  53. Huang S, Czech MP. The GLUT4 glucose transporter. Cell Metab. 2007 Apr; 5(4):237-52.
    View in: PubMed
    Score: 0.020
  54. Huang S, Lifshitz LM, Jones C, Bellve KD, Standley C, Fonseca S, Corvera S, Fogarty KE, Czech MP. Insulin stimulates membrane fusion and GLUT4 accumulation in clathrin coats on adipocyte plasma membranes. Mol Cell Biol. 2007 May; 27(9):3456-69.
    View in: PubMed
    Score: 0.020
  55. Puri V, Chakladar A, Virbasius JV, Konda S, Powelka AM, Chouinard M, Hagan GN, Perugini R, Czech MP. RNAi-based gene silencing in primary mouse and human adipose tissues. J Lipid Res. 2007 Feb; 48(2):465-71.
    View in: PubMed
    Score: 0.019
  56. Czech MP. MicroRNAs as therapeutic targets. N Engl J Med. 2006 Mar 16; 354(11):1194-5.
    View in: PubMed
    Score: 0.018
  57. Tang X, Guilherme A, Chakladar A, Powelka AM, Konda S, Virbasius JV, Nicoloro SM, Straubhaar J, Czech MP. An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARgamma, adipogenesis, and insulin-responsive hexose transport. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2087-92.
    View in: PubMed
    Score: 0.018
  58. Czech MP. ARNT misbehavin' in diabetic beta cells. Nat Med. 2006 Jan; 12(1):39-40.
    View in: PubMed
    Score: 0.018
  59. Powelka AM, Seth A, Virbasius JV, Kiskinis E, Nicoloro SM, Guilherme A, Tang X, Straubhaar J, Cherniack AD, Parker MG, Czech MP. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest. 2006 Jan; 116(1):125-36.
    View in: PubMed
    Score: 0.018
  60. Bose A, Guilherme A, Huang S, Hubbard AC, Lane CR, Soriano NA, Czech MP. The v-SNARE Vti1a regulates insulin-stimulated glucose transport and Acrp30 secretion in 3T3-L1 adipocytes. J Biol Chem. 2005 Nov 04; 280(44):36946-51.
    View in: PubMed
    Score: 0.018
  61. Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells. J Biol Chem. 2005 Jun 03; 280(22):21622-8.
    View in: PubMed
    Score: 0.017
  62. Valeros J, Jerome M, Tseyang T, Vo P, Do T, Fajardo Palomino D, Grotehans N, Kunala M, Jerrett AE, Hathiramani NR, Mireku M, Magesh RY, Yenilmez B, Rosen PC, Mann JL, Myers JW, Kunchok T, Manning TL, Boercker LN, Carr PE, Munim MB, Lewis CA, Sabatini DM, Kelly M, Xie J, Czech MP, Gao G, Shepherd JN, Walker AK, Kim H, Watson EV, Spinelli JB. Rhodoquinone carries electrons in the mammalian electron transport chain. Cell. 2025 Feb 20; 188(4):1084-1099.e27.
    View in: PubMed
    Score: 0.017
  63. Nandy A, Helderman RCM, Thapa S, Peck SH, Richards A, Jayapalan S, Narayani N, Czech MP, Rosen CJ, Rendina-Ruedy E. Enhanced fatty acid oxidation in osteoprogenitor cells provides protection from high-fat diet induced bone dysfunction. J Bone Miner Res. 2025 Feb 02; 40(2):283-298.
    View in: PubMed
    Score: 0.017
  64. Harris JE, Bishop KD, Phillips NE, Mordes JP, Greiner DL, Rossini AA, Czech MP. Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells. J Immunol. 2004 Dec 15; 173(12):7331-8.
    View in: PubMed
    Score: 0.017
  65. Huang S, Lifshitz L, Patki-Kamath V, Tuft R, Fogarty K, Czech MP. Phosphatidylinositol-4,5-bisphosphate-rich plasma membrane patches organize active zones of endocytosis and ruffling in cultured adipocytes. Mol Cell Biol. 2004 Oct; 24(20):9102-23.
    View in: PubMed
    Score: 0.017
  66. Mitra P, Zheng X, Czech MP. RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin. J Biol Chem. 2004 Sep 03; 279(36):37431-5.
    View in: PubMed
    Score: 0.016
  67. Guilherme A, Soriano NA, Furcinitti PS, Czech MP. Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. J Biol Chem. 2004 Sep 17; 279(38):40062-75.
    View in: PubMed
    Score: 0.016
  68. Bose A, Robida S, Furcinitti PS, Chawla A, Fogarty K, Corvera S, Czech MP. Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathway. Mol Cell Biol. 2004 Jun; 24(12):5447-58.
    View in: PubMed
    Score: 0.016
  69. Guilherme A, Soriano NA, Bose S, Holik J, Bose A, Pomerleau DP, Furcinitti P, Leszyk J, Corvera S, Czech MP. EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. J Biol Chem. 2004 Mar 12; 279(11):10593-605.
    View in: PubMed
    Score: 0.016
  70. Czech MP. Insulin's expanding control of forkheads. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11198-200.
    View in: PubMed
    Score: 0.016
  71. Jiang ZY, Zhou QL, Coleman KA, Chouinard M, Boese Q, Czech MP. Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7569-74.
    View in: PubMed
    Score: 0.015
  72. Semiz S, Park JG, Nicoloro SM, Furcinitti P, Zhang C, Chawla A, Leszyk J, Czech MP. Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubules. EMBO J. 2003 May 15; 22(10):2387-99.
    View in: PubMed
    Score: 0.015
  73. Bose A, Guilherme A, Robida SI, Nicoloro SM, Zhou QL, Jiang ZY, Pomerleau DP, Czech MP. Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c. Nature. 2002 Dec 19-26; 420(6917):821-4.
    View in: PubMed
    Score: 0.015
  74. Czech MP. Dynamics of phosphoinositides in membrane retrieval and insertion. Annu Rev Physiol. 2003; 65:791-815.
    View in: PubMed
    Score: 0.015
  75. Helderman RC, Whitney DG, Duta-Mare M, Akhmetshina A, Vujic N, Jayapalan S, Nyman JS, Misra BB, Rosen CJ, Czech MP, Kratky D, Rendina-Ruedy E. Loss of function of lysosomal acid lipase (LAL) profoundly impacts osteoblastogenesis and increases fracture risk in humans. Bone. 2021 07; 148:115946.
    View in: PubMed
    Score: 0.013
  76. Li Q, Nirala NK, Chen HJ, Nie Y, Wang W, Zhang B, Czech MP, Wang Q, Xu L, Mao J, Ip YT. The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. J Cell Physiol. 2019 12; 234(12):21925-21936.
    View in: PubMed
    Score: 0.011
  77. Blaszczak AM, Wright VP, Anandani K, Liu J, Jalilvand A, Bergin S, Nicoloro SM, Czech MP, Lafuse W, Deng T, Bradley D, Hsueh WA. Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism. J Immunol. 2019 04 15; 202(8):2451-2459.
    View in: PubMed
    Score: 0.011
  78. Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Bl?her M, Czech MP, Tabas I. Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 03 29; 555(7698):673-677.
    View in: PubMed
    Score: 0.011
  79. Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Mol Metab. 2017 11; 6(11):1517-1528.
    View in: PubMed
    Score: 0.010
  80. Jourdan T, Szanda G, Cinar R, Godlewski G, Holovac DJ, Park JK, Nicoloro S, Shen Y, Liu J, Rosenberg AZ, Liu Z, Czech MP, Kunos G. Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes. Diabetes. 2017 04; 66(4):994-1007.
    View in: PubMed
    Score: 0.010
  81. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li JL, Guilherme A, Guntur K, Czech MP, Collins S. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016 05 02; 126(5):1704-16.
    View in: PubMed
    Score: 0.009
  82. Li Q, Li S, Mana-Capelli S, Roth Flach RJ, Danai LV, Amcheslavsky A, Nie Y, Kaneko S, Yao X, Chen X, Cotton JL, Mao J, McCollum D, Jiang J, Czech MP, Xu L, Ip YT. The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Dev Cell. 2014 Nov 10; 31(3):291-304.
    View in: PubMed
    Score: 0.008
  83. Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE. Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. Nat Commun. 2014 Mar 19; 5:3485.
    View in: PubMed
    Score: 0.008
  84. Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metab. 2014 Jan 07; 19(1):162-171.
    View in: PubMed
    Score: 0.008
  85. Jourdan T, Godlewski G, Cinar R, Bertola A, Szanda G, Liu J, Tam J, Han T, Mukhopadhyay B, Skarulis MC, Ju C, Aouadi M, Czech MP, Kunos G. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. Nat Med. 2013 Sep; 19(9):1132-40.
    View in: PubMed
    Score: 0.008
  86. Young JL, Mora A, Cerny A, Czech MP, Woda B, Kurt-Jones EA, Finberg RW, Corvera S. CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone. PLoS One. 2012; 7(1):e29688.
    View in: PubMed
    Score: 0.007
  87. Xie X, Gong Z, Mansuy-Aubert V, Zhou QL, Tatulian SA, Sehrt D, Gnad F, Brill LM, Motamedchaboki K, Chen Y, Czech MP, Mann M, Kr?ger M, Jiang ZY. C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane. Cell Metab. 2011 Sep 07; 14(3):378-89.
    View in: PubMed
    Score: 0.007
  88. Mudhasani R, Puri V, Hoover K, Czech MP, Imbalzano AN, Jones SN. Dicer is required for the formation of white but not brown adipose tissue. J Cell Physiol. 2011 May; 226(5):1399-406.
    View in: PubMed
    Score: 0.007
  89. Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8.
    View in: PubMed
    Score: 0.006
  90. Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, Dash S, Hyden CS, Bottomley W, Vigouroux C, Magr? J, Raymond-Barker P, Murgatroyd PR, Chawla A, Skepper JN, Chatterjee VK, Suliman S, Patch AM, Agarwal AK, Garg A, Barroso I, Cinti S, Czech MP, Argente J, O'Rahilly S, Savage DB. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med. 2009 Aug; 1(5):280-7.
    View in: PubMed
    Score: 0.006
  91. Marchand P, Antoine M, Le Baut G, Czech M, Baasner S, G?nther E. Synthesis and structure-activity relationships of N-aryl(indol-3-yl)glyoxamides as antitumor agents. Bioorg Med Chem. 2009 Sep 15; 17(18):6715-27.
    View in: PubMed
    Score: 0.006
  92. Padmanabhan S, Mukhopadhyay A, Narasimhan SD, Tesz G, Czech MP, Tissenbaum HA. A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation. Cell. 2009 Mar 06; 136(5):939-51.
    View in: PubMed
    Score: 0.006
  93. Bishop KD, Harris JE, Mordes JP, Greiner DL, Rossini AA, Czech MP, Phillips NE. Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism. Cell Immunol. 2009; 256(1-2):86-91.
    View in: PubMed
    Score: 0.006
  94. Shi X, Burkart A, Nicoloro SM, Czech MP, Straubhaar J, Corvera S. Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells. J Biol Chem. 2008 Nov 07; 283(45):30658-67.
    View in: PubMed
    Score: 0.005
  95. Wang H, Zhang Y, Yehuda-Shnaidman E, Medvedev AV, Kumar N, Daniel KW, Robidoux J, Czech MP, Mangelsdorf DJ, Collins S. Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype. Mol Cell Biol. 2008 Apr; 28(7):2187-200.
    View in: PubMed
    Score: 0.005
  96. DiNitto JP, Delprato A, Gabe Lee MT, Cronin TC, Huang S, Guilherme A, Czech MP, Lambright DG. Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors. Mol Cell. 2007 Nov 30; 28(4):569-83.
    View in: PubMed
    Score: 0.005
  97. Saito T, Jones CC, Huang S, Czech MP, Pilch PF. The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation. J Biol Chem. 2007 Nov 02; 282(44):32280-7.
    View in: PubMed
    Score: 0.005
  98. Liu L, Song X, He D, Komma C, Kita A, Virbasius JV, Huang G, Bellamy HD, Miki K, Czech MP, Zhou GW. Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha. J Biol Chem. 2006 Feb 17; 281(7):4254-60.
    View in: PubMed
    Score: 0.005
  99. Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes. J Biol Chem. 2005 Jun 10; 280(23):22523-9.
    View in: PubMed
    Score: 0.004
  100. Wilson-Fritch L, Nicoloro S, Chouinard M, Lazar MA, Chui PC, Leszyk J, Straubhaar J, Czech MP, Corvera S. Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. J Clin Invest. 2004 Nov; 114(9):1281-9.
    View in: PubMed
    Score: 0.004
  101. Jaeschke A, Czech MP, Davis RJ. An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue. Genes Dev. 2004 Aug 15; 18(16):1976-80.
    View in: PubMed
    Score: 0.004
  102. Wilson-Fritch L, Burkart A, Bell G, Mendelson K, Leszyk J, Nicoloro S, Czech M, Corvera S. Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone. Mol Cell Biol. 2003 Feb; 23(3):1085-94.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.