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Connection

Michael Czech to Insulin Resistance

This is a "connection" page, showing publications Michael Czech has written about Insulin Resistance.
Connection Strength

5.642
  1. Czech MP. Mechanisms of insulin resistance related to white, beige, and brown adipocytes. Mol Metab. 2020 04; 34:27-42.
    View in: PubMed
    Score: 0.524
  2. Czech MP. Insulin action and resistance in obesity and type 2 diabetes. Nat Med. 2017 Jul 11; 23(7):804-814.
    View in: PubMed
    Score: 0.441
  3. Roth Flach RJ, DiStefano MT, Danai LV, Senol-Cosar O, Yawe JC, Kelly M, Garcia Menendez L, Czech MP. Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2017 09 01; 313(3):E303-E313.
    View in: PubMed
    Score: 0.439
  4. DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP. Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance. Mol Metab. 2016 12; 5(12):1149-1161.
    View in: PubMed
    Score: 0.418
  5. Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP. Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia. J Biol Chem. 2016 07 29; 291(31):16221-30.
    View in: PubMed
    Score: 0.408
  6. Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016 Feb 16; 7:10686.
    View in: PubMed
    Score: 0.400
  7. Fitzgibbons TP, Czech MP. Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance. J Mol Med (Berl). 2016 Mar; 94(3):267-75.
    View in: PubMed
    Score: 0.400
  8. Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. FASEB J. 2015 Jul; 29(7):2959-69.
    View in: PubMed
    Score: 0.376
  9. Guo CA, Kogan S, Amano SU, Wang M, Dagdeviren S, Friedline RH, Aouadi M, Kim JK, Czech MP. CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance. Am J Physiol Endocrinol Metab. 2013 May 01; 304(9):E951-63.
    View in: PubMed
    Score: 0.327
  10. Hardy OT, Perugini RA, Nicoloro SM, Gallagher-Dorval K, Puri V, Straubhaar J, Czech MP. Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity. Surg Obes Relat Dis. 2011 Jan-Feb; 7(1):60-7.
    View in: PubMed
    Score: 0.270
  11. Puri V, Ranjit S, Konda S, Nicoloro SM, Straubhaar J, Chawla A, Chouinard M, Lin C, Burkart A, Corvera S, Perugini RA, Czech MP. Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7833-8.
    View in: PubMed
    Score: 0.234
  12. Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol. 2008 May; 9(5):367-77.
    View in: PubMed
    Score: 0.233
  13. Guilherme A, Henriques F, Bedard AH, Czech MP. Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus. Nat Rev Endocrinol. 2019 04; 15(4):207-225.
    View in: PubMed
    Score: 0.124
  14. Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Bl?her M, Czech MP, Tabas I. Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 03 29; 555(7698):673-677.
    View in: PubMed
    Score: 0.116
  15. Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Mol Metab. 2017 11; 6(11):1517-1528.
    View in: PubMed
    Score: 0.111
  16. Virbasius JV, Czech MP. Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases. Trends Endocrinol Metab. 2016 07; 27(7):484-492.
    View in: PubMed
    Score: 0.102
  17. Danai LV, Flach RJ, Virbasius JV, Menendez LG, Jung DY, Kim JH, Kim JK, Czech MP. Inducible Deletion of Protein Kinase Map4k4 in Obese Mice Improves Insulin Sensitivity in Liver and Adipose Tissues. Mol Cell Biol. 2015 Jul; 35(13):2356-65.
    View in: PubMed
    Score: 0.096
  18. Fitzgibbons TP, Czech MP. Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations. J Am Heart Assoc. 2014 Mar 04; 3(2):e000582.
    View in: PubMed
    Score: 0.087
  19. Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 2013 May; 56(5):949-64.
    View in: PubMed
    Score: 0.081
  20. Sartorius T, Staiger H, Ketterer C, Heni M, Machicao F, Guilherme A, Grallert H, Schulze MB, Boeing H, Stefan N, Fritsche A, Czech MP, H?ring HU. Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans. PLoS One. 2012; 7(10):e47647.
    View in: PubMed
    Score: 0.079
  21. Hardy OT, Czech MP, Corvera S. What causes the insulin resistance underlying obesity? Curr Opin Endocrinol Diabetes Obes. 2012 Apr; 19(2):81-7.
    View in: PubMed
    Score: 0.077
  22. Corvera S, Czech MP. Tensions rise and blood flows over dysfunctional fat. Circulation. 2011 Jul 05; 124(1):13-6.
    View in: PubMed
    Score: 0.073
  23. Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, Dash S, Hyden CS, Bottomley W, Vigouroux C, Magr? J, Raymond-Barker P, Murgatroyd PR, Chawla A, Skepper JN, Chatterjee VK, Suliman S, Patch AM, Agarwal AK, Garg A, Barroso I, Cinti S, Czech MP, Argente J, O'Rahilly S, Savage DB. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med. 2009 Aug; 1(5):280-7.
    View in: PubMed
    Score: 0.064
  24. Tesz GJ, Guilherme A, Guntur KV, Hubbard AC, Tang X, Chawla A, Czech MP. Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. J Biol Chem. 2007 Jul 06; 282(27):19302-12.
    View in: PubMed
    Score: 0.055
  25. Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, Saltiel AR, Corkey BE, Atkinson MA. Voices: Insulin and beyond. Cell Metab. 2021 04 06; 33(4):692-699.
    View in: PubMed
    Score: 0.036
  26. Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE. Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction. Nat Commun. 2014 Mar 19; 5:3485.
    View in: PubMed
    Score: 0.022
  27. Jourdan T, Godlewski G, Cinar R, Bertola A, Szanda G, Liu J, Tam J, Han T, Mukhopadhyay B, Skarulis MC, Ju C, Aouadi M, Czech MP, Kunos G. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. Nat Med. 2013 Sep; 19(9):1132-40.
    View in: PubMed
    Score: 0.021
  28. Gealekman O, Guseva N, Hartigan C, Apotheker S, Gorgoglione M, Gurav K, Tran KV, Straubhaar J, Nicoloro S, Czech MP, Thompson M, Perugini RA, Corvera S. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity. Circulation. 2011 Jan 18; 123(2):186-94.
    View in: PubMed
    Score: 0.018
  29. Jaeschke A, Czech MP, Davis RJ. An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue. Genes Dev. 2004 Aug 15; 18(16):1976-80.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.