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John Mordes to Rats

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This is a "connection" page, showing publications John Mordes has written about Rats.
John Mordes
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1.724
Rats
  1. Mordes JP, Cort L, Liu Z, Eberwine R, Blankenhorn EP, Pierce BG. T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes. Genes (Basel). 2021 06 01; 12(6).
    View in: PubMed
    Score: 0.141
  2. Liu Z, Cort L, Eberwine R, Herrmann T, Leif JH, Greiner DL, Yahalom B, Blankenhorn EP, Mordes JP. Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: V?13 as a therapeutic target and biomarker. Diabetes. 2012 May; 61(5):1160-8.
    View in: PubMed
    Score: 0.074
  3. Tirabassi RS, Guberski DL, Blankenhorn EP, Leif JH, Woda BA, Liu Z, Winans D, Greiner DL, Mordes JP. Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization. Diabetes. 2010 Jan; 59(1):110-8.
    View in: PubMed
    Score: 0.063
  4. Blankenhorn EP, Cort L, Greiner DL, Guberski DL, Mordes JP. Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex. Diabetes. 2009 Dec; 58(12):2930-8.
    View in: PubMed
    Score: 0.062
  5. Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP. Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mamm Genome. 2009 Mar; 20(3):162-9.
    View in: PubMed
    Score: 0.060
  6. Blankenhorn EP, Descipio C, Rodemich L, Cort L, Leif JH, Greiner DL, Mordes JP. Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene. Ann N Y Acad Sci. 2007 Apr; 1103:128-31.
    View in: PubMed
    Score: 0.053
  7. Mordes JP, Guberski DL, Leif JH, Woda BA, Flanagan JF, Greiner DL, Kislauskis EH, Tirabassi RS. LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes. 2005 Sep; 54(9):2727-33.
    View in: PubMed
    Score: 0.047
  8. Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes. 2005 Apr; 54(4):1233-7.
    View in: PubMed
    Score: 0.046
  9. Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
    View in: PubMed
    Score: 0.045
  10. Mordes JP, Bortell R, Blankenhorn EP, Rossini AA, Greiner DL. Rat models of type 1 diabetes: genetics, environment, and autoimmunity. ILAR J. 2004; 45(3):278-91.
    View in: PubMed
    Score: 0.042
  11. Mordes JP, Leif J, Novak S, DeScipio C, Greiner DL, Blankenhorn EP. The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats. Diabetes. 2002 Nov; 51(11):3254-62.
    View in: PubMed
    Score: 0.039
  12. Bogdani M, Faxius L, Fex M, Ramelius A, Wernersson A, Mordes JP, Blankenhorn EP, Lernmark ?. The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats. Front Endocrinol (Lausanne). 2021; 12:629242.
    View in: PubMed
    Score: 0.035
  13. Gordon EJ, Woda BA, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells. Transplantation. 2001 Jan 27; 71(2):319-27.
    View in: PubMed
    Score: 0.034
  14. Iwakoshi NN, Greiner DL, Rossini AA, Mordes JP. Diabetes prone BB rats are severely deficient in natural killer T cells. Autoimmunity. 1999; 31(1):1-14.
    View in: PubMed
    Score: 0.030
  15. Qaisar N, Lin S, Ryan G, Yang C, Oikemus SR, Brodsky MH, Bortell R, Mordes JP, Wang JP. A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats. Diabetes. 2017 Jan; 66(1):145-157.
    View in: PubMed
    Score: 0.025
  16. Doukas J, Majno G, Mordes JP. Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM. Diabetes. 1996 Sep; 45(9):1209-16.
    View in: PubMed
    Score: 0.025
  17. Mordes JP, Bortell R, Doukas J, Rigby M, Whalen B, Zipris D, Greiner DL, Rossini AA. The BB/Wor rat and the balance hypothesis of autoimmunity. Diabetes Metab Rev. 1996 Jul; 12(2):103-9.
    View in: PubMed
    Score: 0.025
  18. Mordes JP, Schirf B, Roipko D, Greiner DL, Weiner H, Nelson P, Rossini AA. Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats. Ann N Y Acad Sci. 1996 Feb 13; 778:418-21.
    View in: PubMed
    Score: 0.024
  19. Doukas J, Cutler AH, Mordes JP. Polyinosinic:polycytidylic acid is a potent activator of endothelial cells. Am J Pathol. 1994 Jul; 145(1):137-47.
    View in: PubMed
    Score: 0.022
  20. Cort L, Habib M, Eberwine RA, Hessner MJ, Mordes JP, Blankenhorn EP. Diubiquitin (Ubd) is a susceptibility gene for virus-triggered autoimmune diabetes in rats. Genes Immun. 2014 Apr-May; 15(3):168-75.
    View in: PubMed
    Score: 0.021
  21. Eberwine RA, Cort L, Habib M, Mordes JP, Blankenhorn EP. Autoantigen-induced focusing of V?13+ T cells precedes onset of autoimmune diabetes in the LEW.1WR1 rat. Diabetes. 2014 Feb; 63(2):596-604.
    View in: PubMed
    Score: 0.021
  22. Chen YG, Mordes JP, Blankenhorn EP, Kashmiri H, Kaldunski ML, Jia S, Geoffrey R, Wang X, Hessner MJ. Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes. Genes Immun. 2013 Sep; 14(6):387-400.
    View in: PubMed
    Score: 0.020
  23. Kitagawa Y, Desemone J, Mordes JP. Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors. Immunopharmacology. 1993 May-Jun; 25(3):229-38.
    View in: PubMed
    Score: 0.020
  24. Doukas J, Mordes JP. T lymphocytes capable of activating endothelial cells in vitro are present in rats with autoimmune diabetes. J Immunol. 1993 Feb 01; 150(3):1036-46.
    View in: PubMed
    Score: 0.020
  25. Rossini AA, Handler ES, Greiner DL, Mordes JP. Insulin dependent diabetes mellitus hypothesis of autoimmunity. Autoimmunity. 1991; 8(3):221-35.
    View in: PubMed
    Score: 0.017
  26. Kruger AJ, Yang C, Tam SW, Hinerfeld D, Evans JE, Green KM, Leszyk J, Yang K, Guberski DL, Mordes JP, Greiner DL, Rossini AA, Bortell R. Haptoglobin as an early serum biomarker of virus-induced autoimmune type 1 diabetes in biobreeding diabetes resistant and LEW1.WR1 rats. Exp Biol Med (Maywood). 2010 Nov; 235(11):1328-37.
    View in: PubMed
    Score: 0.017
  27. Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat. Diabetes. 2010 Oct; 59(10):2375-85.
    View in: PubMed
    Score: 0.017
  28. Desemone J, Majno G, Joris I, Handler ES, Rossini AA, Mordes JP. Morphological and physiological characteristics of pancreas-specific venular permeability induced by Monastral blue B. Exp Mol Pathol. 1990 Feb; 52(1):141-53.
    View in: PubMed
    Score: 0.016
  29. Pino SC, O'Sullivan-Murphy B, Lidstone EA, Yang C, Lipson KL, Jurczyk A, diIorio P, Brehm MA, Mordes JP, Greiner DL, Rossini AA, Bortell R. CHOP mediates endoplasmic reticulum stress-induced apoptosis in Gimap5-deficient T cells. PLoS One. 2009; 4(5):e5468.
    View in: PubMed
    Score: 0.015
  30. Fuller JM, Bogdani M, Tupling TD, Jensen RA, Pefley R, Manavi S, Cort L, Blankenhorn EP, Mordes JP, Lernmark A, Kwitek AE. Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene. Physiol Genomics. 2009 Jun 10; 38(1):89-97.
    View in: PubMed
    Score: 0.015
  31. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.015
  32. Gottlieb PA, Rossini AA, Mordes JP. Approaches to prevention and treatment of IDDM in animal models. Diabetes Care. 1988 Nov-Dec; 11 Suppl 1:29-36.
    View in: PubMed
    Score: 0.015
  33. Mordes JP, Desemone J, Rossini AA. The BB rat. Diabetes Metab Rev. 1987 Jul; 3(3):725-50.
    View in: PubMed
    Score: 0.013
  34. Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P. A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Diabetes. 2007 Jun; 56(6):1731-6.
    View in: PubMed
    Score: 0.013
  35. Zipris D, Lien E, Nair A, Xie JX, Greiner DL, Mordes JP, Rossini AA. TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat. J Immunol. 2007 Jan 15; 178(2):693-701.
    View in: PubMed
    Score: 0.013
  36. Mordes JP, Gallina DL, Handler ES, Greiner DL, Nakamura N, Pelletier A, Rossini AA. Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat. Diabetologia. 1987 Jan; 30(1):22-6.
    View in: PubMed
    Score: 0.013
  37. Hillebrands JL, Whalen B, Visser JT, Koning J, Bishop KD, Leif J, Rozing J, Mordes JP, Greiner DL, Rossini AA. A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3. J Immunol. 2006 Dec 01; 177(11):7820-32.
    View in: PubMed
    Score: 0.013
  38. Phillips NE, Greiner DL, Mordes JP, Rossini AA. Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation. Transplantation. 2006 Oct 27; 82(8):1085-92.
    View in: PubMed
    Score: 0.013
  39. Morrison AR, Moss J, Stevens LA, Evans JE, Farrell C, Merithew E, Lambright DG, Greiner DL, Mordes JP, Rossini AA, Bortell R. ART2, a T cell surface mono-ADP-ribosyltransferase, generates extracellular poly(ADP-ribose). J Biol Chem. 2006 Nov 03; 281(44):33363-72.
    View in: PubMed
    Score: 0.013
  40. Mordes JP, Handler ES, Like AA, Nakano K, Rossini AA. Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat. Metabolism. 1986 Jun; 35(6):552-4.
    View in: PubMed
    Score: 0.012
  41. Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA. Costimulation and autoimmune diabetes in BB rats. Am J Transplant. 2006 May; 6(5 Pt 1):894-902.
    View in: PubMed
    Score: 0.012
  42. Masaki H, Appel MC, Leahy L, Leif J, Paquin L, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice. Xenotransplantation. 2006 May; 13(3):224-32.
    View in: PubMed
    Score: 0.012
  43. Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP, Rossini AA. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol. 2005 Jan 01; 174(1):131-42.
    View in: PubMed
    Score: 0.011
  44. Mordes JP, Longcope C, Flatt JP, MacLean DB, Rossini AA. The rat LTW(m) Leydig cell tumor: cancer anorexia due to estrogen. Endocrinology. 1984 Jul; 115(1):167-73.
    View in: PubMed
    Score: 0.011
  45. Rossini AA, Faustman D, Woda BA, Like AA, Szymanski I, Mordes JP. Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat. J Clin Invest. 1984 Jul; 74(1):39-46.
    View in: PubMed
    Score: 0.011
  46. Rossini AA, Slavin S, Woda BA, Geisberg M, Like AA, Mordes JP. Total lymphoid irradiation prevents diabetes mellitus in the Bio-Breeding/Worcester (BB/W) rat. Diabetes. 1984 Jun; 33(6):543-7.
    View in: PubMed
    Score: 0.011
  47. Todd DJ, Forsberg EM, Greiner DL, Mordes JP, Rossini AA, Bortell R. Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J Immunol. 2004 May 01; 172(9):5356-62.
    View in: PubMed
    Score: 0.011
  48. Hornum L, DeScipio C, Markholst H, Troutman SA, Novak S, Leif J, Greiner D, Mordes JP, Blankenhorn EP. Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6. Mamm Genome. 2004 Jan; 15(1):53-61.
    View in: PubMed
    Score: 0.011
  49. Pandarpurkar M, Wilson-Fritch L, Corvera S, Markholst H, Hornum L, Greiner DL, Mordes JP, Rossini AA, Bortell R. Ian4 is required for mitochondrial integrity and T cell survival. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10382-7.
    View in: PubMed
    Score: 0.010
  50. Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, Greiner DL, Rossini AA. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J Immunol. 2003 Apr 01; 170(7):3592-602.
    View in: PubMed
    Score: 0.010
  51. Whalen BJ, Marounek J, Mordes JP, Rossini AA, Greiner DL. Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures. J Autoimmun. 2003 Feb; 20(1):27-42.
    View in: PubMed
    Score: 0.010
  52. Todd DJ, Greiner DL, Rossini AA, Mordes JP, Bortell R. An atypical population of NK cells that spontaneously secrete IFN-gamma and IL-4 is present in the intraepithelial lymphoid compartment of the rat. J Immunol. 2001 Oct 01; 167(7):3600-9.
    View in: PubMed
    Score: 0.009
  53. Bortell R, Moss J, McKenna RC, Rigby MR, Niedzwiecki D, Stevens LA, Patton WA, Mordes JP, Greiner DL, Rossini AA. Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. J Immunol. 2001 Aug 15; 167(4):2049-59.
    View in: PubMed
    Score: 0.009
  54. Mordes JP, Rossini AA. Tumor-induced anorexia in the Wistar rat. Science. 1981 Jul 31; 213(4507):565-7.
    View in: PubMed
    Score: 0.009
  55. Whalen BJ, Marounek J, Weiser P, Appel MC, Greiner DL, Mordes JP, Rossini AA. BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes. Diabetes. 2001 May; 50(5):972-9.
    View in: PubMed
    Score: 0.009
  56. Bortel R, Waite DJ, Whalen BJ, Todd D, Leif JH, Lesma E, Moss J, Mordes JP, Rossini AA, Greiner DL. Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat. Autoimmunity. 2001 May; 33(3):199-211.
    View in: PubMed
    Score: 0.009
  57. Whalen BJ, Mordes JP, Rossini AA. The BB rat as a model of human insulin-dependent diabetes mellitus. Curr Protoc Immunol. 2001 May; Chapter 15:15.3.1-15.3.15.
    View in: PubMed
    Score: 0.009
  58. Mordes JP, Rossini AA. Animal models of diabetes. Am J Med. 1981 Feb; 70(2):353-60.
    View in: PubMed
    Score: 0.009
  59. Zipris D, Leif J, Deluca D, Lin MY, Mordes JP, Rossini AA, Greiner DL, Whalen BJ. Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture. Cell Mol Biol (Noisy-le-grand). 2001 Feb; 47(1):65-74.
    View in: PubMed
    Score: 0.009
  60. Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP. Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4. Diabetes. 1999 Nov; 48(11):2138-44.
    View in: PubMed
    Score: 0.008
  61. Whalen BJ, Love LC, Mordes JP, Rossini AA, Greiner DL. Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes. Transplant Proc. 1999 May; 31(3):1611-4.
    View in: PubMed
    Score: 0.008
  62. Todd D, Singh AJ, Greiner DL, Mordes JP, Rossini AA, Bortell R. A new isolation method for rat intraepithelial lymphocytes. J Immunol Methods. 1999 Apr 22; 224(1-2):111-27.
    View in: PubMed
    Score: 0.008
  63. Whalen BJ, Weiser P, Marounek J, Rossini AA, Mordes JP, Greiner DL. Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture. J Immunol. 1999 Apr 01; 162(7):4003-12.
    View in: PubMed
    Score: 0.008
  64. Bortell R, Kanaitsuka T, Stevens LA, Moss J, Mordes JP, Rossini AA, Greiner DL. The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse. Mol Cell Biochem. 1999 Mar; 193(1-2):61-8.
    View in: PubMed
    Score: 0.008
  65. Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL. Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. Diabetes. 1999 Jan; 48(1):50-8.
    View in: PubMed
    Score: 0.007
  66. Lesma E, Moss J, Brewer HB, Bortell R, Greiner D, Mordes J, Rossini AA. Characterization of high density lipoprotein-bound and soluble RT6 released following administration of anti-RT6.1 monoclonal antibody. J Immunol. 1998 Aug 01; 161(3):1212-9.
    View in: PubMed
    Score: 0.007
  67. Gordon EJ, Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody. Diabetes. 1998 Aug; 47(8):1199-206.
    View in: PubMed
    Score: 0.007
  68. Iwakoshi NN, Goldschneider I, Tausche F, Mordes JP, Rossini AA, Greiner DL. High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats. J Immunol. 1998 Jun 15; 160(12):5838-50.
    View in: PubMed
    Score: 0.007
  69. Kanaitsuka T, Bortell R, Stevens LA, Moss J, Sardinha D, Rajan TV, Zipris D, Mordes JP, Greiner DL, Rossini AA. Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout. J Immunol. 1997 Sep 15; 159(6):2741-9.
    View in: PubMed
    Score: 0.007
  70. Malkani S, Nompleggi D, Hansen JW, Greiner DL, Mordes JP, Rossini AA. Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat. Diabetes. 1997 Jul; 46(7):1133-40.
    View in: PubMed
    Score: 0.007
  71. Whalen BJ, Doukas J, Mordes JP, Rossini AA, Greiner DL. Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats. Transplant Proc. 1997 May; 29(3):1684-5.
    View in: PubMed
    Score: 0.007
  72. Moss J, Stevens LA, Cavanaugh E, Okazaki IJ, Bortell R, Kanaitsuka T, Mordes JP, Greiner DL, Rossini AA. Characterization of mouse Rt6.1 NAD:arginine ADP-ribosyltransferase. J Biol Chem. 1997 Feb 14; 272(7):4342-6.
    View in: PubMed
    Score: 0.007
  73. Bortell R, Rigby M, Stevens L, Moss J, Kanaitsuka T, Mordes J, Greiner D, Rossini A. Mouse RT6 locus 1 and rat RT6.2 are NAD+. Arginine ADP-ribosyltransferases with auto-ADP-ribosylation activity. Adv Exp Med Biol. 1997; 419:169-73.
    View in: PubMed
    Score: 0.006
  74. Greiner DL, Malkani S, Kanaitsuka T, Bortell R, Doukas J, Rigby M, Whalen B, Stevens LA, Moss J, Mordes JP, Rossini AA. The T cell marker RT6 in a rat model of autoimmune diabetes. Adv Exp Med Biol. 1997; 419:209-16.
    View in: PubMed
    Score: 0.006
  75. Rigby MR, Bortell R, Greiner DL, Czech MP, Klarlund JK, Mordes JP, Rossini AA. The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal. Diabetes. 1996 Oct; 45(10):1419-26.
    View in: PubMed
    Score: 0.006
  76. Rigby MR, Bortell R, Stevens LA, Moss J, Kanaitsuka T, Shigeta H, Mordes JP, Greiner DL, Rossini AA. Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity. J Immunol. 1996 Jun 01; 156(11):4259-65.
    View in: PubMed
    Score: 0.006
  77. Waite DJ, Appel MC, Handler ES, Mordes JP, Rossini AA, Greiner DL. Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat. Am J Pathol. 1996 Jun; 148(6):2043-56.
    View in: PubMed
    Score: 0.006
  78. Markees TG, Appel MC, Noelle RJ, Mordes JP, Greiner DL, Rossini AA. Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation. Transplant Proc. 1996 Apr; 28(2):814-5.
    View in: PubMed
    Score: 0.006
  79. Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP, Rossini AA. Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. J Immunol. 1996 Feb 01; 156(3):1315-21.
    View in: PubMed
    Score: 0.006
  80. Whalen BJ, Rossini AA, Mordes JP, Greiner DL. DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity. Diabetes. 1995 Aug; 44(8):963-7.
    View in: PubMed
    Score: 0.006
  81. Rossini AA, Handler ES, Mordes JP, Greiner DL. Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. Clin Immunol Immunopathol. 1995 Jan; 74(1):2-9.
    View in: PubMed
    Score: 0.006
  82. Whalen BJ, Greiner DL, Mordes JP, Rossini AA. Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells. J Autoimmun. 1994 Dec; 7(6):819-31.
    View in: PubMed
    Score: 0.006
  83. Doukas J, Mordes JP, Swymer C, Niedzwiecki D, Mason R, Rozing J, Rossini AA, Greiner DL. Thymic epithelial defects and predisposition to autoimmune disease in BB rats. Am J Pathol. 1994 Dec; 145(6):1517-25.
    View in: PubMed
    Score: 0.006
  84. Battan R, Mordes JP, Abreau S, Greiner DL, Handler ES, Rossini AA. Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats. Transplantation. 1994 Mar 15; 57(5):731-6.
    View in: PubMed
    Score: 0.005
  85. Sarkar P, Cris? L, McKeever U, Bortell R, Handler E, Mordes JP, Waite D, Schoenbaum A, Haag F, Koch-Nolte F, et al. Loss of RT6 message and most circulating T cells after thymectomy of diabetes prone BB rats. Autoimmunity. 1994; 18(1):15-22.
    View in: PubMed
    Score: 0.005
  86. Jiang Z, Makowiecki J, Mordes JP, Woda BA. Cytolysin gene expression in the islets of diabetic BioBreeding/Worcester rats. J Immunol. 1994 Jan 01; 152(1):322-9.
    View in: PubMed
    Score: 0.005
  87. Waite DJ, Handler ES, Mordes JP, Rossini AA, Greiner DL. The RT6 rat lymphocyte alloantigen circulates in soluble form. Cell Immunol. 1993 Nov; 152(1):82-95.
    View in: PubMed
    Score: 0.005
  88. Cris? L, Sarkar P, Waite DJ, Friedrich FH, Rajan TV, Mordes JP, Handler ES, Thiele HG, Rossini AA, et al. An RT6a gene is transcribed and translated in lymphopenic diabetes-prone BB rats. Diabetes. 1993 May; 42(5):688-95.
    View in: PubMed
    Score: 0.005
  89. Tafuri A, Bowers WE, Handler ES, Appel M, Lew R, Greiner D, Mordes JP, Rossini AA. High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors. J Clin Invest. 1993 May; 91(5):2040-8.
    View in: PubMed
    Score: 0.005
  90. Cris? L, Mordes JP, Rossini AA. Autoimmune diabetes mellitus in the BB rat. Diabetes Metab Rev. 1992 Apr; 8(1):4-37.
    View in: PubMed
    Score: 0.005
  91. Kitagawa Y, Greiner DL, Reynolds CW, Ortaldo JR, Toccafondi R, Handler ES, van der Meide PH, Mordes JP, Rossini AA. Islet cells but not thyrocytes are susceptible to lysis by NK cells. J Autoimmun. 1991 Oct; 4(5):703-16.
    View in: PubMed
    Score: 0.004
  92. Greiner DL, Shultz LD, Rossini AA, Mordes JP, Handler ES, Rajan TV. Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras. J Clin Invest. 1991 Aug; 88(2):717-9.
    View in: PubMed
    Score: 0.004
  93. Gottlieb PA, Handler ES, Appel MC, Greiner DL, Mordes JP, Rossini AA. Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats. Diabetologia. 1991 May; 34(5):296-300.
    View in: PubMed
    Score: 0.004
  94. Woda BA, Handler ES, Greiner DL, Reynolds C, Mordes JP, Rossini AA. T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats. Diabetes. 1991 Apr; 40(4):423-8.
    View in: PubMed
    Score: 0.004
  95. Thomas VA, Woda BA, Handler ES, Greiner DL, Mordes JP, Rossini AA. Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens. Diabetes. 1991 Feb; 40(2):255-8.
    View in: PubMed
    Score: 0.004
  96. Cris? L, Greiner DL, Mordes JP, MacDonald RG, Handler ES, Czech MP, Rossini AA. Biochemical studies of RT6 alloantigens in BB/Wor and normal rats. Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats. Diabetes. 1990 Oct; 39(10):1279-88.
    View in: PubMed
    Score: 0.004
  97. McKeever U, Mordes JP, Greiner DL, Appel MC, Rozing J, Handler ES, Rossini AA. Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7618-22.
    View in: PubMed
    Score: 0.004
  98. Nakamura N, Woda BA, Tafuri A, Greiner DL, Reynolds CW, Ortaldo J, Chick W, Handler ES, Mordes JP, Rossini AA. Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro. Diabetes. 1990 Jul; 39(7):836-43.
    View in: PubMed
    Score: 0.004
  99. Markholst H, Klaff LJ, Kl?ppel G, Lernmark A, Mordes JP, Palmer J. Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats. Diabetes. 1990 Jun; 39(6):720-7.
    View in: PubMed
    Score: 0.004
  100. Gottlieb PA, Berrios JP, Mariani G, Handler ES, Greiner D, Mordes JP, Rossini AA. Autoimmune destruction of islets transplanted into RT6-depleted diabetes-resistant BB/Wor rats. Diabetes. 1990 May; 39(5):643-5.
    View in: PubMed
    Score: 0.004
  101. Abend S, Cormier J, Appel MC, Lueprasitsakul W, Alex S, Mordes JP, Usadel KH, Handler ES, Rossini AA, Braverman LE. The effect of ciamexone on lymphocytic thyroiditis and insulin-dependent diabetes mellitus in the BB/Wor rat. Immunopharmacology. 1990 May-Jun; 19(3):163-8.
    View in: PubMed
    Score: 0.004
  102. Lefkowith J, Schreiner G, Cormier J, Handler ES, Driscoll HK, Greiner D, Mordes JP, Rossini AA. Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes. J Exp Med. 1990 Mar 01; 171(3):729-43.
    View in: PubMed
    Score: 0.004
  103. Driscoll HK, Gottlieb PA, Mordes JP, Matschinsky FM, Rossini AA. Plasma from BB/Wor rats increases insulin secretion by perfused rat pancreas. Endocrinology. 1990 Feb; 126(2):1241-9.
    View in: PubMed
    Score: 0.004
  104. Handler ES, Mordes JP, McKeever U, Nakamura N, Bernhard J, Greiner DL, Rossini AA. Effects of irradiation on diabetes in the BB/Wor rat. Autoimmunity. 1989; 4(1-2):21-30.
    View in: PubMed
    Score: 0.004
  105. Burstein D, Mordes JP, Greiner DL, Stein D, Nakamura N, Handler ES, Rossini AA. Prevention of diabetes in BB/Wor rat by single transfusion of spleen cells. Parameters that affect degree of protection. Diabetes. 1989 Jan; 38(1):24-30.
    View in: PubMed
    Score: 0.004
  106. Rossini AA, Mordes JP, Greiner DL. The pathogenesis of autoimmune diabetes mellitus. Curr Opin Immunol. 1989-1990 Apr; 2(4):598-603.
    View in: PubMed
    Score: 0.004
  107. Angelillo M, Greiner DL, Mordes JP, Handler ES, Nakamura N, McKeever U, Rossini A. Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects. J Immunol. 1988 Dec 15; 141(12):4146-51.
    View in: PubMed
    Score: 0.004
  108. Nakano K, Mordes JP, Handler ES, Greiner DL, Rossini AA. Role of host immune system in BB/Wor rat. Predisposition to diabetes resides in bone marrow. Diabetes. 1988 May; 37(5):520-5.
    View in: PubMed
    Score: 0.004
  109. Greiner DL, Angelillo M, Mordes JP, Handler ES, Mojcik CF, Nakamura N, Rossini AA. Regulatory T cell control of autoimmune destruction of beta cells in the BB rat. Adv Exp Med Biol. 1988; 246:379-85.
    View in: PubMed
    Score: 0.003
  110. Greiner DL, Mordes JP, Handler ES, Angelillo M, Nakamura N, Rossini AA. Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats. J Exp Med. 1987 Aug 01; 166(2):461-75.
    View in: PubMed
    Score: 0.003
  111. Burstein D, Handler ES, Schindler J, Seals J, Mordes JP, Rossini AA. Effect of interleukin-2 on diabetes in the BB/Wor rat. Diabetes Res. 1987 Aug; 5(4):163-7.
    View in: PubMed
    Score: 0.003
  112. Majno G, Joris I, Handler ES, Desemone J, Mordes JP, Rossini AA. A pancreatic venular defect in the BB/Wor rat. Am J Pathol. 1987 Aug; 128(2):210-5.
    View in: PubMed
    Score: 0.003
  113. Greiner DL, Mordes JP, Handler ES, Nakamura N, Angelillo M, Rossini AA. Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities. Transplant Proc. 1987 Feb; 19(1 Pt 2):976-8.
    View in: PubMed
    Score: 0.003
  114. Rossini AA, Mordes JP, Greiner DL, Nakano K, Appel MC, Handler ES. Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells. J Clin Invest. 1986 Apr; 77(4):1399-401.
    View in: PubMed
    Score: 0.003
  115. Greiner DL, Handler ES, Nakano K, Mordes JP, Rossini AA. Absence of the RT-6 T cell subset in diabetes-prone BB/W rats. J Immunol. 1986 Jan; 136(1):148-51.
    View in: PubMed
    Score: 0.003
  116. Malhotra A, Mordes JP, McDermott L, Schaible TF. Abnormal cardiac biochemistry in spontaneously diabetic Bio-Breeding/Worcester rat. Am J Physiol. 1985 Nov; 249(5 Pt 2):H1051-5.
    View in: PubMed
    Score: 0.003
  117. Handler ES, Mordes JP, Seals J, Koevary S, Like AA, Nakano K, Rossini AA. Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media. J Clin Invest. 1985 Oct; 76(4):1692-4.
    View in: PubMed
    Score: 0.003
  118. Rossini AA, Mordes JP, Like AA. Immunology of insulin-dependent diabetes mellitus. Annu Rev Immunol. 1985; 3:289-320.
    View in: PubMed
    Score: 0.003
  119. Rossini AA, Mordes JP, Gallina DL, Like AA. Hormonal and environmental factors in the pathogenesis of BB rat diabetes. Metabolism. 1983 Jul; 32(7 Suppl 1):33-6.
    View in: PubMed
    Score: 0.003
  120. Rossini AA, Mordes JP, Williams RM, Pelletier AM, Like AA. Failure to transfer insulitis to athymic recipients using BB/W rat lymphoid tissue transplants. Metabolism. 1983 Jul; 32(7 Suppl 1):80-2.
    View in: PubMed
    Score: 0.003
  121. Rossini AA, Mordes JP, Pelletier AM, Like AA. Transfusions of whole blood prevent spontaneous diabetes mellitus in the BB/W rat. Science. 1983 Feb 25; 219(4587):975-7.
    View in: PubMed
    Score: 0.002
  122. Rossini AA, Williams RM, Mordes JP, Appel MC, Like AA. Spontaneous diabetes in the gnotobiotic BB/W rat. Diabetes. 1979 Nov; 28(11):1031-2.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.