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Connection

Juleen Zierath to Insulin

This is a "connection" page, showing publications Juleen Zierath has written about Insulin.
Connection Strength

5.270
  1. Benziane B, Borg ML, Tom RZ, Riedl I, Massart J, Bj?rnholm M, Gilbert M, Chibalin AV, Zierath JR. DGK? deficiency protects against peripheral insulin resistance and improves energy metabolism. J Lipid Res. 2017 12; 58(12):2324-2333.
    View in: PubMed
    Score: 0.433
  2. Mudry JM, Lassiter DG, Nyl?n C, Garc?a-Calz?n S, N?slund E, Krook A, Zierath JR. Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle. Diabetes. 2017 03; 66(3):651-662.
    View in: PubMed
    Score: 0.409
  3. Zachariah Tom R, Garcia-Roves PM, Sj?gren RJ, Jiang LQ, Holmstr?m MH, Deshmukh AS, Vieira E, Chibalin AV, Bj?rnholm M, Zierath JR. Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes. 2014 May; 63(5):1560-71.
    View in: PubMed
    Score: 0.335
  4. Sogaard P, Szekeres F, Garcia-Roves PM, Larsson D, Chibalin AV, Zierath JR. Spatial insulin signalling in isolated skeletal muscle preparations. J Cell Biochem. 2010 Apr 01; 109(5):943-9.
    View in: PubMed
    Score: 0.257
  5. Karlsson HK, Zierath JR. Insulin signaling and glucose transport in insulin resistant human skeletal muscle. Cell Biochem Biophys. 2007; 48(2-3):103-13.
    View in: PubMed
    Score: 0.205
  6. Ryder JW, Long YC, Nilsson E, Mahlapuu M, Zierath JR. Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle. J Physiol. 2005 Sep 01; 567(Pt 2):379-86.
    View in: PubMed
    Score: 0.184
  7. Karlsson HK, H?llsten K, Bj?rnholm M, Tsuchida H, Chibalin AV, Virtanen KA, Heinonen OJ, L?nnqvist F, Nuutila P, Zierath JR. Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study. Diabetes. 2005 May; 54(5):1459-67.
    View in: PubMed
    Score: 0.182
  8. Rizo-Roca D, Guimar?es DSPSF, Pendergrast LA, Di Leo N, Chibalin AV, Maqdasy S, Ryd?n M, N?slund E, Zierath JR, Krook A. Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes. Sci Transl Med. 2024 Oct 09; 16(768):eado3022.
    View in: PubMed
    Score: 0.176
  9. Leng Y, Steiler TL, Zierath JR. Effects of insulin, contraction, and phorbol esters on mitogen-activated protein kinase signaling in skeletal muscle from lean and ob/ob mice. Diabetes. 2004 Jun; 53(6):1436-44.
    View in: PubMed
    Score: 0.171
  10. Leng Y, Karlsson HK, Zierath JR. Insulin signaling defects in type 2 diabetes. Rev Endocr Metab Disord. 2004 May; 5(2):111-7.
    View in: PubMed
    Score: 0.170
  11. Koistinen HA, Forsgren M, Wallberg-Henriksson H, Zierath JR. Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects. Obes Res. 2004 Jan; 12(1):25-31.
    View in: PubMed
    Score: 0.166
  12. Zierath JR, Kawano Y. The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle. Best Pract Res Clin Endocrinol Metab. 2003 Sep; 17(3):385-98.
    View in: PubMed
    Score: 0.163
  13. Ryder JW, Bassel-Duby R, Olson EN, Zierath JR. Skeletal muscle reprogramming by activation of calcineurin improves insulin action on metabolic pathways. J Biol Chem. 2003 Nov 07; 278(45):44298-304.
    View in: PubMed
    Score: 0.162
  14. Kemppainen J, Tsuchida H, Stolen K, Karlsson H, Bj?rnholm M, Heinonen OJ, Nuutila P, Krook A, Knuuti J, Zierath JR. Insulin signalling and resistance in patients with chronic heart failure. J Physiol. 2003 Jul 01; 550(Pt 1):305-15.
    View in: PubMed
    Score: 0.159
  15. Zierath JR. Invited review: Exercise training-induced changes in insulin signaling in skeletal muscle. J Appl Physiol (1985). 2002 Aug; 93(2):773-81.
    View in: PubMed
    Score: 0.151
  16. Stocks B, Zierath JR. Post-translational Modifications: The Signals at the Intersection of Exercise, Glucose Uptake, and Insulin Sensitivity. Endocr Rev. 2022 07 13; 43(4):654-677.
    View in: PubMed
    Score: 0.150
  17. Zierath JR, Wallberg-Henriksson H. From receptor to effector: insulin signal transduction in skeletal muscle from type II diabetic patients. Ann N Y Acad Sci. 2002 Jun; 967:120-34.
    View in: PubMed
    Score: 0.149
  18. Small L, Ehrlich A, Iversen J, Ashcroft SP, Tro?t K, Moritz T, Hartmann B, Holst JJ, Treebak JT, Zierath JR, Barr?s R. Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice. Mol Metab. 2022 03; 57:101440.
    View in: PubMed
    Score: 0.145
  19. Karlsson HKR, Kasahara A, Ikeda M, Chibalin AV, Harada J, Ryd?n M, Krook A, Kato M, Kubota K, Zierath JR. Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study. Metabolism. 2021 05; 118:154726.
    View in: PubMed
    Score: 0.136
  20. Dalbram E, Basse AL, Zierath JR, Treebak JT. Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action. J Appl Physiol (1985). 2019 04 01; 126(4):993-1005.
    View in: PubMed
    Score: 0.118
  21. Ruby MA, Massart J, Hunerdosse DM, Sch?nke M, Correia JC, Louie SM, Ruas JL, N?slund E, Nomura DK, Zierath JR. Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance. Cell Rep. 2017 01 17; 18(3):636-646.
    View in: PubMed
    Score: 0.103
  22. Cartee GD, Hepple RT, Bamman MM, Zierath JR. Exercise Promotes Healthy Aging of Skeletal Muscle. Cell Metab. 2016 06 14; 23(6):1034-1047.
    View in: PubMed
    Score: 0.099
  23. Al-Khalili L, de Castro Barbosa T, Ostling J, Massart J, Cuesta PG, Osler ME, Katayama M, Nystr?m AC, Oscarsson J, Zierath JR. Proteasome inhibition in skeletal muscle cells unmasks metabolic derangements in type 2 diabetes. Am J Physiol Cell Physiol. 2014 Nov 01; 307(9):C774-87.
    View in: PubMed
    Score: 0.087
  24. Szekeres F, Chadt A, Tom RZ, Deshmukh AS, Chibalin AV, Bj?rnholm M, Al-Hasani H, Zierath JR. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism. Am J Physiol Endocrinol Metab. 2012 Aug 15; 303(4):E524-33.
    View in: PubMed
    Score: 0.075
  25. Karlsson HK, Chibalin AV, Koistinen HA, Yang J, Koumanov F, Wallberg-Henriksson H, Zierath JR, Holman GD. Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes. 2009 Apr; 58(4):847-54.
    View in: PubMed
    Score: 0.059
  26. Deshmukh AS, Treebak JT, Long YC, Viollet B, Wojtaszewski JF, Zierath JR. Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling. Mol Endocrinol. 2008 May; 22(5):1105-12.
    View in: PubMed
    Score: 0.055
  27. Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 2006 Jul; 4(1):89-96.
    View in: PubMed
    Score: 0.049
  28. Karlsson HK, Ahls?n M, Zierath JR, Wallberg-Henriksson H, Koistinen HA. Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients. Diabetes. 2006 May; 55(5):1283-8.
    View in: PubMed
    Score: 0.049
  29. Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK. Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes. 2005 Oct; 54(10):2939-45.
    View in: PubMed
    Score: 0.047
  30. Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H. Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes. 2005 Jun; 54(6):1692-7.
    View in: PubMed
    Score: 0.046
  31. Bouzakri K, Koistinen HA, Zierath JR. Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes. Curr Diabetes Rev. 2005 May; 1(2):167-74.
    View in: PubMed
    Score: 0.046
  32. Zierath JR. Kinases in diabetes. Part II. 11-12 November 2004, Manchester, UK. IDrugs. 2005 Feb; 8(2):121-3.
    View in: PubMed
    Score: 0.045
  33. Krook A, Wallberg-Henriksson H, Zierath JR. Sending the signal: molecular mechanisms regulating glucose uptake. Med Sci Sports Exerc. 2004 Jul; 36(7):1212-7.
    View in: PubMed
    Score: 0.043
  34. Al-Khalili L, Krook A, Zierath JR, Cartee GD. Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake. Am J Physiol Endocrinol Metab. 2004 Sep; 287(3):E553-7.
    View in: PubMed
    Score: 0.043
  35. Karlsson HK, Nilsson PA, Nilsson J, Chibalin AV, Zierath JR, Blomstrand E. Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. Am J Physiol Endocrinol Metab. 2004 Jul; 287(1):E1-7.
    View in: PubMed
    Score: 0.042
  36. Storgaard H, Jensen CB, Bj?rnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA. Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab. 2004 Mar; 89(3):1301-11.
    View in: PubMed
    Score: 0.042
  37. Steiler TL, Galuska D, Leng Y, Chibalin AV, Gilbert M, Zierath JR. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology. 2003 Dec; 144(12):5259-67.
    View in: PubMed
    Score: 0.041
  38. Isaksson B, Str?mmer L, Friess H, B?chler MW, Herrington MK, Wang F, Zierath JR, Wallberg-Henriksson H, Larsson J, Permert J. Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients. Pancreas. 2003 Mar; 26(2):173-7.
    View in: PubMed
    Score: 0.039
  39. Dollet L, Kuefner M, Caria E, Rizo-Roca D, Pendergrast L, Abdelmoez AM, Karlsson HKR, Bj?rnholm M, Dalbram E, Treebak JT, Harada J, N?slund E, Ryd?n M, Zierath JR, Pillon NJ, Krook A. Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes. Diabetes. 2022 04 01; 71(4):624-636.
    View in: PubMed
    Score: 0.037
  40. Katayama M, Wiklander OPB, Fritz T, Caidahl K, El-Andaloussi S, Zierath JR, Krook A. Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle. Diabetes. 2019 03; 68(3):515-526.
    View in: PubMed
    Score: 0.029
  41. Nyl?n C, Lundell LS, Massart J, Zierath JR, N?slund E. Short-term low-calorie diet remodels skeletal muscle lipid profile and metabolic gene expression in obese adults. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E178-E185.
    View in: PubMed
    Score: 0.029
  42. Kj?bsted R, Treebak JT, Fentz J, Lantier L, Viollet B, Birk JB, Schjerling P, Bj?rnholm M, Zierath JR, Wojtaszewski JF. Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner. Diabetes. 2015 Jun; 64(6):2042-55.
    View in: PubMed
    Score: 0.022
  43. Moltke I, Grarup N, J?rgensen ME, Bjerregaard P, Treebak JT, Fumagalli M, Korneliussen TS, Andersen MA, Nielsen TS, Krarup NT, Gjesing AP, Zierath JR, Linneberg A, Wu X, Sun G, Jin X, Al-Aama J, Wang J, Borch-Johnsen K, Pedersen O, Nielsen R, Albrechtsen A, Hansen T. A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Nature. 2014 Aug 14; 512(7513):190-3.
    View in: PubMed
    Score: 0.021
  44. Mashili FL, Austin RL, Deshmukh AS, Fritz T, Caidahl K, Bergdahl K, Zierath JR, Chibalin AV, Moller DE, Kharitonenkov A, Krook A. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. Diabetes Metab Res Rev. 2011 Mar; 27(3):286-97.
    View in: PubMed
    Score: 0.017
  45. Benziane B, Bj?rnholm M, Lantier L, Viollet B, Zierath JR, Chibalin AV. AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1554-66.
    View in: PubMed
    Score: 0.016
  46. Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A. siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. Diabetes. 2008 Aug; 57(8):2066-73.
    View in: PubMed
    Score: 0.014
  47. Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J, Laville M, Guillet C, Boirie Y, Wallberg-Henriksson H, Manco M, Calvani M, Castagneto M, Palac?n M, Mingrone G, Zierath JR, Vidal H, Zorzano A. Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes. 2005 Sep; 54(9):2685-93.
    View in: PubMed
    Score: 0.012
  48. Barnes BR, Marklund S, Steiler TL, Walter M, Hj?lm G, Amarger V, Mahlapuu M, Leng Y, Johansson C, Galuska D, Lindgren K, Abrink M, Stapleton D, Zierath JR, Andersson L. The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle. J Biol Chem. 2004 Sep 10; 279(37):38441-7.
    View in: PubMed
    Score: 0.011
  49. Al-Khalili L, Chibalin AV, Yu M, Sj?din B, Nyl?n C, Zierath JR, Krook A. MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am J Physiol Cell Physiol. 2004 Jun; 286(6):C1410-6.
    View in: PubMed
    Score: 0.010
  50. Koistinen HA, Galuska D, Chibalin AV, Yang J, Zierath JR, Holman GD, Wallberg-Henriksson H. 5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes. 2003 May; 52(5):1066-72.
    View in: PubMed
    Score: 0.010
  51. Ceddia RB, Koistinen HA, Zierath JR, Sweeney G. Analysis of paradoxical observations on the association between leptin and insulin resistance. FASEB J. 2002 Aug; 16(10):1163-76.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.