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Juleen Zierath to Male

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This is a "connection" page, showing publications Juleen Zierath has written about Male.
Juleen Zierath
Connection Strength
1.784
Male
  1. Ehrlich AM, MacGregor KA, Ashcroft SP, Small L, Altintas A, Chibalin AV, Anagho-Mattanovich M, Stocks B, Moritz T, Treebak JT, Zierath JR. HIF1a mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise. Proc Natl Acad Sci U S A. 2025 Jul 15; 122(28):e2504080122.
    View in: PubMed
    Score: 0.056
  2. Ashcroft SP, Ehrlich AM, Burek K, Pendergrast LA, Yonamine CY, Treebak JT, Zierath JR. Enhanced metabolic adaptations following late dark phase wheel running in high-fat diet-fed mice. Mol Metab. 2025 May; 95:102116.
    View in: PubMed
    Score: 0.055
  3. Katayama M, Nomura K, Mudry JM, Chibalin AV, Krook A, Zierath JR. Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle. Mol Metab. 2025 Feb; 92:102081.
    View in: PubMed
    Score: 0.054
  4. Jollet M, Tramontana F, Jiang LQ, Borg ML, Savikj M, Kuefner MS, Massart J, de Castro Barbosa T, Manner?s-Holm L, Checa A, Pillon NJ, Chibalin AV, Bj?rnholm M, Zierath JR. Diacylglycerol kinase delta overexpression improves glucose clearance and protects against the development of obesity. Metabolism. 2024 Sep; 158:155939.
    View in: PubMed
    Score: 0.052
  5. Pendergrast LA, Ashcroft SP, Ehrlich AM, Treebak JT, Krook A, Dollet L, Zierath JR. Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice. Metabolism. 2024 Jun; 155:155834.
    View in: PubMed
    Score: 0.051
  6. Karlsson HKR, Kasahara A, Ikeda M, Chibalin AV, Harada J, Ryd?n M, Krook A, Kato M, Kubota K, Zierath JR. Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study. Metabolism. 2021 05; 118:154726.
    View in: PubMed
    Score: 0.041
  7. Sardon Puig L, Pillon NJ, N?slund E, Krook A, Zierath JR. Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression. Am J Physiol Endocrinol Metab. 2020 01 01; 318(1):E1-E10.
    View in: PubMed
    Score: 0.038
  8. Borg ML, Massart J, Sch?nke M, De Castro Barbosa T, Guo L, Wade M, Alsina-Fernandez J, Miles R, Ryan A, Bauer S, Coskun T, O'Farrell E, Niemeier EM, Chibalin AV, Krook A, Karlsson HK, Brozinick JT, Zierath JR. Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice. Diabetes. 2019 07; 68(7):1403-1414.
    View in: PubMed
    Score: 0.037
  9. Gabriel BM, Zierath JR. Circadian rhythms and exercise - re-setting the clock in metabolic disease. Nat Rev Endocrinol. 2019 04; 15(4):197-206.
    View in: PubMed
    Score: 0.036
  10. de Castro Barbosa T, Alm PS, Krook A, Barr?s R, Zierath JR. Paternal high-fat diet transgenerationally impacts hepatic immunometabolism. FASEB J. 2019 05; 33(5):6269-6280.
    View in: PubMed
    Score: 0.036
  11. Lundell LS, Massart J, Altintas A, Krook A, Zierath JR. Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle. Mol Metab. 2019 02; 20:79-88.
    View in: PubMed
    Score: 0.035
  12. Lassiter DG, Sj?gren RJO, Gabriel BM, Krook A, Zierath JR. AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle. Mol Metab. 2018 10; 16:12-23.
    View in: PubMed
    Score: 0.035
  13. Sch?nke M, Massart J, Zierath JR. Effects of high-fat diet and AMP-activated protein kinase modulation on the regulation of whole-body lipid metabolism. J Lipid Res. 2018 07; 59(7):1276-1282.
    View in: PubMed
    Score: 0.034
  14. Benziane B, Borg ML, Tom RZ, Riedl I, Massart J, Bj?rnholm M, Gilbert M, Chibalin AV, Zierath JR. DGK? deficiency protects against peripheral insulin resistance and improves energy metabolism. J Lipid Res. 2017 12; 58(12):2324-2333.
    View in: PubMed
    Score: 0.033
  15. Lassiter DG, Nyl?n C, Sj?gren RJO, Chibalin AV, Wallberg-Henriksson H, N?slund E, Krook A, Zierath JR. FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle. Diabetologia. 2018 02; 61(2):424-432.
    View in: PubMed
    Score: 0.033
  16. Ruby MA, Riedl I, Massart J, ?hlin M, Zierath JR. Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle. Am J Physiol Endocrinol Metab. 2017 10 01; 313(4):E483-E491.
    View in: PubMed
    Score: 0.032
  17. Alm PS, de Castro Barbosa T, Barr?s R, Krook A, Zierath JR. Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle. Mol Metab. 2017 07; 6(7):621-630.
    View in: PubMed
    Score: 0.032
  18. Manner?s-Holm L, Sch?nke M, Brozinick JT, Vetterli L, Bui HH, Sanders P, Nascimento EBM, Bj?rnholm M, Chibalin AV, Zierath JR. Diacylglycerol kinase e deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice. J Lipid Res. 2017 05; 58(5):907-915.
    View in: PubMed
    Score: 0.032
  19. Ruby MA, Massart J, Hunerdosse DM, Sch?nke M, Correia JC, Louie SM, Ruas JL, N?slund E, Nomura DK, Zierath JR. Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance. Cell Rep. 2017 01 17; 18(3):636-646.
    View in: PubMed
    Score: 0.031
  20. Mudry JM, Lassiter DG, Nyl?n C, Garc?a-Calz?n S, N?slund E, Krook A, Zierath JR. Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle. Diabetes. 2017 03; 66(3):651-662.
    View in: PubMed
    Score: 0.031
  21. Barr?s R, Zierath JR. The role of diet and exercise in the transgenerational epigenetic landscape of T2DM. Nat Rev Endocrinol. 2016 08; 12(8):441-51.
    View in: PubMed
    Score: 0.030
  22. Jiang LQ, de Castro Barbosa T, Massart J, Deshmukh AS, L?fgren L, Duque-Guimaraes DE, Ozilgen A, Osler ME, Chibalin AV, Zierath JR. Diacylglycerol kinase-d regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics. Am J Physiol Endocrinol Metab. 2016 Jan 01; 310(1):E51-60.
    View in: PubMed
    Score: 0.029
  23. Wallberg-Henriksson H, Zierath JR. Metabolism. Exercise remodels subcutaneous fat tissue and improves metabolism. Nat Rev Endocrinol. 2015 Apr; 11(4):198-200.
    View in: PubMed
    Score: 0.027
  24. Al-Khalili L, de Castro Barbosa T, Ostling J, Massart J, Cuesta PG, Osler ME, Katayama M, Nystr?m AC, Oscarsson J, Zierath JR. Proteasome inhibition in skeletal muscle cells unmasks metabolic derangements in type 2 diabetes. Am J Physiol Cell Physiol. 2014 Nov 01; 307(9):C774-87.
    View in: PubMed
    Score: 0.026
  25. Zachariah Tom R, Garcia-Roves PM, Sj?gren RJ, Jiang LQ, Holmstr?m MH, Deshmukh AS, Vieira E, Chibalin AV, Bj?rnholm M, Zierath JR. Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes. 2014 May; 63(5):1560-71.
    View in: PubMed
    Score: 0.025
  26. Nascimento EB, Osler ME, Zierath JR. Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle. Am J Physiol Endocrinol Metab. 2013 Dec 01; 305(11):E1408-14.
    View in: PubMed
    Score: 0.025
  27. Holmstr?m MH, Tom RZ, Bj?rnholm M, Garcia-Roves PM, Zierath JR. Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice. Metabolism. 2013 Sep; 62(9):1258-67.
    View in: PubMed
    Score: 0.024
  28. Mashili F, Chibalin AV, Krook A, Zierath JR. Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes. Diabetes. 2013 Feb; 62(2):457-65.
    View in: PubMed
    Score: 0.023
  29. Szekeres F, Chadt A, Tom RZ, Deshmukh AS, Chibalin AV, Bj?rnholm M, Al-Hasani H, Zierath JR. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism. Am J Physiol Endocrinol Metab. 2012 Aug 15; 303(4):E524-33.
    View in: PubMed
    Score: 0.023
  30. Barr?s R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, Caidahl K, Krook A, O'Gorman DJ, Zierath JR. Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab. 2012 Mar 07; 15(3):405-11.
    View in: PubMed
    Score: 0.022
  31. Kulkarni SS, Karlsson HK, Szekeres F, Chibalin AV, Krook A, Zierath JR. Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle. J Biol Chem. 2011 Oct 07; 286(40):34567-74.
    View in: PubMed
    Score: 0.022
  32. Deshmukh AS, Glund S, Tom RZ, Zierath JR. Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle. Am J Physiol Endocrinol Metab. 2009 Dec; 297(6):E1388-94.
    View in: PubMed
    Score: 0.019
  33. Chibalin AV, Leng Y, Vieira E, Krook A, Bj?rnholm M, Long YC, Kotova O, Zhong Z, Sakane F, Steiler T, Nyl?n C, Wang J, Laakso M, Topham MK, Gilbert M, Wallberg-Henriksson H, Zierath JR. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell. 2008 Feb 08; 132(3):375-86.
    View in: PubMed
    Score: 0.017
  34. Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 2006 Jul; 4(1):89-96.
    View in: PubMed
    Score: 0.015
  35. Deshmukh A, Coffey VG, Zhong Z, Chibalin AV, Hawley JA, Zierath JR. Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle. Diabetes. 2006 Jun; 55(6):1776-82.
    View in: PubMed
    Score: 0.015
  36. Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR. IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. Diabetes. 2006 Mar; 55(3):785-91.
    View in: PubMed
    Score: 0.015
  37. Sen I, Smith JAB, Caria E, Orlov I, Savikj M, Brady AJ, Lian K, Ellefsen S, Zierath JR, Krook A. Down-regulation of human-specific lncRNA TMEM9B-AS1 in skeletal muscle of people with type 2 diabetes affects ribosomal biogenesis. Sci Adv. 2025 Jul 11; 11(28):eads4371.
    View in: PubMed
    Score: 0.014
  38. Keller MJ, Brady AJ, Smith JAB, Savikj M, MacGregor K, Jollet M, ?berg SB, Nyl?n C, Bj?rnholm M, Rickenlund A, Carlsson M, Caidahl K, Krook A, Pillon NJ, Zierath JR, Wallberg-Henriksson H. Inflammatory markers and blood glucose are higher after morning vs afternoon exercise in type 2 diabetes. Diabetologia. 2025 Sep; 68(9):2023-2035.
    View in: PubMed
    Score: 0.014
  39. Kj?rgaard J, Lindqvist CB, Quesada JP, Jessen S, Schlabs F, Ehrlich AM, Yonamine CY, Garc?a-Ure?a M, Schmalbruch JH, Small L, Thomassen M, Lemminger AK, Eibye K, Gonzalez-Franquesa A, Stidsen JV, H?jlund K, Zierath JR, Kilpel?inen TO, Bangsbo J, Treebak JT, Hostrup M, Deshmukh AS. Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake. Cell Rep Med. 2025 Jun 17; 6(6):102163.
    View in: PubMed
    Score: 0.014
  40. Kj?rgaard J, Stocks B, Henderson J, Freemantle JB, Rizo-Roca D, Puglia M, Madrazo Montoya M, Andersson D, B?ckdahl J, Eriksson-Hogling D, Stidsen JV, Wierer M, Rasmussen S, Sakamoto K, H?jlund K, Ryd?n M, Zierath JR, Krook A, Deshmukh AS. Personalized molecular signatures of insulin resistance and type 2 diabetes. Cell. 2025 Jul 24; 188(15):4106-4122.e16.
    View in: PubMed
    Score: 0.014
  41. Pinto-Hernandez P, Fernandez-Sanjurjo M, Paget D, Caravia XM, Roiz-Valle D, Castilla-Silgado J, Diez-Robles S, Coto-Vilcapoma A, Fernandez-Vivero D, Gama-Perez P, Garcia-Roves PM, Lopez-Otin C, Zierath JR, Krook A, Fernandez-Garcia B, Tomas-Zapico C, Iglesias-Gutierrez E. Training-induced plasma miR-29a-3p is secreted by skeletal muscle and contributes to metabolic adaptations to resistance exercise in mice. Mol Metab. 2025 Aug; 98:102173.
    View in: PubMed
    Score: 0.014
  42. Chubanava S, Karavaeva I, Ehrlich AM, Justicia RM, Basse AL, Kulik I, Dalbram E, Ahwazi D, Heaselgrave SR, Tro?t K, Stocks B, Hodek O, Rodrigues RN, Havelund JF, Schlabs FL, Larsen S, Yonamine CY, Henriquez-Olgu?n C, Giustarini D, Rossi R, Gerhart-Hines Z, Moritz T, Zierath JR, Sakamoto K, Jensen TE, F?rgeman NJ, Lavery GG, Deshmukh AS, Treebak JT. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging. Cell Metab. 2025 Jul 01; 37(7):1460-1481.e17.
    View in: PubMed
    Score: 0.014
  43. Stocks B, Quesada JP, Mozzicato AM, Jacob C, Jensen S, MacGregor KA, Bangsbo J, Zierath JR, Hostrup M, Deshmukh AS. Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise. Sci Adv. 2025 Jan 31; 11(5):eadp8608.
    View in: PubMed
    Score: 0.014
  44. Rizo-Roca D, Guimar?es DSPSF, Pendergrast LA, Di Leo N, Chibalin AV, Maqdasy S, Ryd?n M, N?slund E, Zierath JR, Krook A. Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes. Sci Transl Med. 2024 10 09; 16(768):eado3022.
    View in: PubMed
    Score: 0.013
  45. Lecoutre S, Maqdasy S, Rizo-Roca D, Renzi G, Vlassakev I, Alaeddine LM, Higos R, Jalkanen J, Zhong J, Zareifi DS, Frendo-Cumbo S, Massier L, Hodek O, Juvany M, Moritz T, de Castro Barbosa T, Omar-Hmeadi M, L?pez-Yus M, Merabtene F, Abatan JB, Marcelin G, El Hachem EJ, Rouault C, Bergo MO, Petrus P, Zierath JR, Cl?ment K, Krook A, Mejhert N, Ryd?n M. Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health. Nat Metab. 2024 Jul; 6(7):1329-1346.
    View in: PubMed
    Score: 0.013
  46. Nomura K, Kinoshita S, Mizusaki N, Senga Y, Sasaki T, Kitamura T, Sakaue H, Emi A, Hosooka T, Matsuo M, Okamura H, Amo T, Wolf AM, Kamimura N, Ohta S, Itoh T, Hayashi Y, Kiyonari H, Krook A, Zierath JR, Kasuga M, Ogawa W. Adaptive gene expression of alternative splicing variants of PGC-1a regulates whole-body energy metabolism. Mol Metab. 2024 Aug; 86:101968.
    View in: PubMed
    Score: 0.013
  47. Jiang S, Yuan T, Rosenberger FA, Mourier A, Dragano NRV, Kremer LS, Rubalcava-Gracia D, Hansen FM, Borg M, Mennuni M, Filograna R, Alsina D, Misic J, Koolmeister C, Papadea P, de Angelis MH, Ren L, Andersson O, Unger A, Bergbrede T, Di Lucrezia R, Wibom R, Zierath JR, Krook A, Giavalisco P, Mann M, Larsson NG. Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nat Metab. 2024 Jun; 6(6):1024-1035.
    View in: PubMed
    Score: 0.013
  48. Guimar?es DSPSF, Barrios NMF, de Oliveira AG, Rizo-Roca D, Jollet M, Smith JAB, Araujo TR, da Cruz MV, Marconato E, Hirabara SM, Vieira AS, Krook A, Zierath JR, Silveira LR. Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6. J Cachexia Sarcopenia Muscle. 2024 Aug; 15(4):1335-1347.
    View in: PubMed
    Score: 0.013
  49. Dollet L, Lundell LS, Chibalin AV, Pendergrast LA, Pillon NJ, Lansbury EL, Elmastas M, Frendo-Cumbo S, Jalkanen J, de Castro Barbosa T, Cervone DT, Caidahl K, Dmytriyeva O, Deshmukh AS, Barr?s R, Ryd?n M, Wallberg-Henriksson H, Zierath JR, Krook A. Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M. Cell Rep Med. 2024 01 16; 5(1):101348.
    View in: PubMed
    Score: 0.013
  50. Steiler TL, Galuska D, Leng Y, Chibalin AV, Gilbert M, Zierath JR. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology. 2003 Dec; 144(12):5259-67.
    View in: PubMed
    Score: 0.012
  51. Kemppainen J, Tsuchida H, Stolen K, Karlsson H, Bj?rnholm M, Heinonen OJ, Nuutila P, Krook A, Knuuti J, Zierath JR. Insulin signalling and resistance in patients with chronic heart failure. J Physiol. 2003 Jul 01; 550(Pt 1):305-15.
    View in: PubMed
    Score: 0.012
  52. Yu M, Stepto NK, Chibalin AV, Fryer LG, Carling D, Krook A, Hawley JA, Zierath JR. Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol. 2003 Jan 15; 546(Pt 2):327-35.
    View in: PubMed
    Score: 0.012
  53. Barnes BR, Ryder JW, Steiler TL, Fryer LG, Carling D, Zierath JR. Isoform-specific regulation of 5' AMP-activated protein kinase in skeletal muscle from obese Zucker (fa/fa) rats in response to contraction. Diabetes. 2002 Sep; 51(9):2703-8.
    View in: PubMed
    Score: 0.012
  54. Savikj M, Stocks B, Sato S, Caidahl K, Krook A, Deshmukh AS, Zierath JR, Wallberg-Henriksson H. Exercise timing influences multi-tissue metabolome and skeletal muscle proteome profiles in type 2 diabetic patients - A randomized crossover trial. Metabolism. 2022 10; 135:155268.
    View in: PubMed
    Score: 0.011
  55. Dollet L, Kuefner M, Caria E, Rizo-Roca D, Pendergrast L, Abdelmoez AM, Karlsson HKR, Bj?rnholm M, Dalbram E, Treebak JT, Harada J, N?slund E, Ryd?n M, Zierath JR, Pillon NJ, Krook A. Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes. Diabetes. 2022 04 01; 71(4):624-636.
    View in: PubMed
    Score: 0.011
  56. Small L, Ehrlich A, Iversen J, Ashcroft SP, Tro?t K, Moritz T, Hartmann B, Holst JJ, Treebak JT, Zierath JR, Barr?s R. Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice. Mol Metab. 2022 03; 57:101440.
    View in: PubMed
    Score: 0.011
  57. Massart J, Sj?gren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barr?s R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nat Commun. 2021 10 12; 12(1):5948.
    View in: PubMed
    Score: 0.011
  58. Gonzalez-Franquesa A, Stocks B, Borg ML, Kuefner M, Dalbram E, Nielsen TS, Agrawal A, Pankratova S, Chibalin AV, Karlsson HKR, Gheibi S, Bj?rnholm M, J?rgensen NR, Clemmensen C, Hostrup M, Treebak JT, Krook A, Zierath JR, Deshmukh AS. Discovery of thymosin ?4 as a human exerkine and growth factor. Am J Physiol Cell Physiol. 2021 11 01; 321(5):C770-C778.
    View in: PubMed
    Score: 0.011
  59. Williams K, Carrasquilla GD, Ingerslev LR, Hochreuter MY, Hansson S, Pillon NJ, Donkin I, Versteyhe S, Zierath JR, Kilpel?inen TO, Barr?s R. Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in whole-body function and human health. Mol Metab. 2021 11; 53:101290.
    View in: PubMed
    Score: 0.011
  60. Smith JAB, Savikj M, Sethi P, Platt S, Gabriel BM, Hawley JA, Dunstan D, Krook A, Zierath JR, N?slund E. Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity. Am J Physiol Endocrinol Metab. 2021 08 01; 321(2):E203-E216.
    View in: PubMed
    Score: 0.011
  61. Lundell LS, Parr EB, Devlin BL, Ingerslev LR, Altintas A, Sato S, Sassone-Corsi P, Barr?s R, Zierath JR, Hawley JA. Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression. Nat Commun. 2020 09 16; 11(1):4643.
    View in: PubMed
    Score: 0.010
  62. Brand?o BB, Madsen S, Rabiee A, Oliverio M, Ruiz GP, Ferrucci DL, Branquinho JL, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Martins AS, Guerra BA, Knittel TL, S?gaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA. Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23932-23941.
    View in: PubMed
    Score: 0.010
  63. Abdelmoez AM, Sard?n Puig L, Smith JAB, Gabriel BM, Savikj M, Dollet L, Chibalin AV, Krook A, Zierath JR, Pillon NJ. Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism. Am J Physiol Cell Physiol. 2020 03 01; 318(3):C615-C626.
    View in: PubMed
    Score: 0.010
  64. Aoi W, Hirano N, Lassiter DG, Bj?rnholm M, Chibalin AV, Sakuma K, Tanimura Y, Mizushima K, Takagi T, Naito Y, Zierath JR, Krook A. Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation. FASEB J. 2019 09; 33(9):10551-10562.
    View in: PubMed
    Score: 0.009
  65. Sato S, Basse AL, Sch?nke M, Chen S, Samad M, Altintas A, Laker RC, Dalbram E, Barr?s R, Baldi P, Treebak JT, Zierath JR, Sassone-Corsi P. Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis. Cell Metab. 2019 07 02; 30(1):92-110.e4.
    View in: PubMed
    Score: 0.009
  66. Dalbram E, Basse AL, Zierath JR, Treebak JT. Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action. J Appl Physiol (1985). 2019 04 01; 126(4):993-1005.
    View in: PubMed
    Score: 0.009
  67. Nyl?n C, Lundell LS, Massart J, Zierath JR, N?slund E. Short-term low-calorie diet remodels skeletal muscle lipid profile and metabolic gene expression in obese adults. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E178-E185.
    View in: PubMed
    Score: 0.009
  68. Savikj M, Gabriel BM, Alm PS, Smith J, Caidahl K, Bj?rnholm M, Fritz T, Krook A, Zierath JR, Wallberg-Henriksson H. Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial. Diabetologia. 2019 02; 62(2):233-237.
    View in: PubMed
    Score: 0.009
  69. Mashili FL, Ramaiya K, Lutale J, Njelekela M, Francis F, Zierath J, Krook A. Adiposity Is a Key Correlate of Circulating Fibroblast Growth Factor-21 Levels in African Males with or without Type 2 Diabetes Mellitus. J Obes. 2018; 2018:7461903.
    View in: PubMed
    Score: 0.009
  70. Cedernaes J, Sch?nke M, Westholm JO, Mi J, Chibalin A, Voisin S, Osler M, Vogel H, H?rnaeus K, Dickson SL, Lind SB, Bergquist J, Schi?th HB, Zierath JR, Benedict C. Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans. Sci Adv. 2018 08; 4(8):eaar8590.
    View in: PubMed
    Score: 0.009
  71. Savikj M, Ruby MA, Kostovski E, Iversen PO, Zierath JR, Krook A, Widegren U. Retained differentiation capacity of human skeletal muscle satellite cells from spinal cord-injured individuals. Physiol Rep. 2018 06; 6(12):e13739.
    View in: PubMed
    Score: 0.009
  72. Sch?nke M, Bj?rnholm M, Chibalin AV, Zierath JR, Deshmukh AS. Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition. Proteomics. 2018 03; 18(5-6):e1700375.
    View in: PubMed
    Score: 0.008
  73. Younis S, Sch?nke M, Massart J, Hjortebjerg R, Sundstr?m E, Gustafson U, Bj?rnholm M, Krook A, Frystyk J, Zierath JR, Andersson L. The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E2048-E2057.
    View in: PubMed
    Score: 0.008
  74. Massart J, Sj?gren RJO, Lundell LS, Mudry JM, Franck N, O'Gorman DJ, Egan B, Zierath JR, Krook A. Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle. Diabetes. 2017 07; 66(7):1807-1818.
    View in: PubMed
    Score: 0.008
  75. Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sj?gren RJ, N?slund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O'Rahilly S, Wareham NJ, Langenberg C. Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. PLoS Med. 2016 Nov; 13(11):e1002179.
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    Score: 0.008
  76. Mudry JM, Alm PS, Erhardt S, Goiny M, Fritz T, Caidahl K, Zierath JR, Krook A, Wallberg-Henriksson H. Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes. Diabetes Metab Res Rev. 2016 10; 32(7):754-761.
    View in: PubMed
    Score: 0.007
  77. Donkin I, Versteyhe S, Ingerslev LR, Qian K, Mechta M, Nordkap L, Mortensen B, Appel EV, J?rgensen N, Kristiansen VB, Hansen T, Workman CT, Zierath JR, Barr?s R. Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans. Cell Metab. 2016 Feb 09; 23(2):369-78.
    View in: PubMed
    Score: 0.007
  78. Sch?nke M, Myers MG, Zierath JR, Bj?rnholm M. Skeletal muscle AMP-activated protein kinase ?1(H151R) overexpression enhances whole body energy homeostasis and insulin sensitivity. Am J Physiol Endocrinol Metab. 2015 Oct 01; 309(7):E679-90.
    View in: PubMed
    Score: 0.007
  79. Cedernaes J, Osler ME, Voisin S, Broman JE, Vogel H, Dickson SL, Zierath JR, Schi?th HB, Benedict C. Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men. J Clin Endocrinol Metab. 2015 Sep; 100(9):E1255-61.
    View in: PubMed
    Score: 0.007
  80. Lane SC, Camera DM, Lassiter DG, Areta JL, Bird SR, Yeo WK, Jeacocke NA, Krook A, Zierath JR, Burke LM, Hawley JA. Effects of sleeping with reduced carbohydrate availability on acute training responses. J Appl Physiol (1985). 2015 Sep 15; 119(6):643-55.
    View in: PubMed
    Score: 0.007
  81. Ring M, Eriksson MJ, Fritz T, Nyberg G, ?stenson CG, Krook A, Zierath JR, Caidahl K. Influence of physical activity and gender on arterial function in type 2 diabetes, normal and impaired glucose tolerance. Diab Vasc Dis Res. 2015 Sep; 12(5):315-24.
    View in: PubMed
    Score: 0.007
  82. Osler ME, Fritz T, Caidahl K, Krook A, Zierath JR, Wallberg-Henriksson H. Changes in gene expression in responders and nonresponders to a low-intensity walking intervention. Diabetes Care. 2015 Jun; 38(6):1154-60.
    View in: PubMed
    Score: 0.007
  83. Multhaup ML, Seldin MM, Jaffe AE, Lei X, Kirchner H, Mondal P, Li Y, Rodriguez V, Drong A, Hussain M, Lindgren C, McCarthy M, N?slund E, Zierath JR, Wong GW, Feinberg AP. Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes. Cell Metab. 2015 Jan 06; 21(1):138-49.
    View in: PubMed
    Score: 0.007
  84. Sj?gren RJ, Egan B, Katayama M, Zierath JR, Krook A. Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells. Physiol Genomics. 2015 Mar; 47(3):45-57.
    View in: PubMed
    Score: 0.007
  85. Ring M, Eriksson MJ, Zierath JR, Caidahl K. Arterial stiffness estimation in healthy subjects: a validation of oscillometric (Arteriograph) and tonometric (SphygmoCor) techniques. Hypertens Res. 2014 Nov; 37(11):999-1007.
    View in: PubMed
    Score: 0.007
  86. Massart J, Zierath JR, Chibalin AV. A simple and rapid method to characterize lipid fate in skeletal muscle. BMC Res Notes. 2014 Jun 24; 7:391.
    View in: PubMed
    Score: 0.007
  87. Kirchner H, Nylen C, Laber S, Barr?s R, Yan J, Krook A, Zierath JR, N?slund E. Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass. Surg Obes Relat Dis. 2014 Jul-Aug; 10(4):671-8.
    View in: PubMed
    Score: 0.006
  88. Jiang LQ, Franck N, Egan B, Sj?gren RJ, Katayama M, Duque-Guimaraes D, Arner P, Zierath JR, Krook A. Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7. Am J Physiol Endocrinol Metab. 2013 Dec 01; 305(11):E1359-66.
    View in: PubMed
    Score: 0.006
  89. Egan B, O'Connor PL, Zierath JR, O'Gorman DJ. Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle. PLoS One. 2013; 8(9):e74098.
    View in: PubMed
    Score: 0.006
  90. Brandauer J, Vienberg SG, Andersen MA, Ringholm S, Risis S, Larsen PS, Kristensen JM, Fr?sig C, Leick L, Fentz J, J?rgensen S, Kiens B, Wojtaszewski JF, Richter EA, Zierath JR, Goodyear LJ, Pilegaard H, Treebak JT. AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle. J Physiol. 2013 Oct 15; 591(20):5207-20.
    View in: PubMed
    Score: 0.006
  91. Dokas J, Chadt A, Nolden T, Himmelbauer H, Zierath JR, Joost HG, Al-Hasani H. Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle. Endocrinology. 2013 Oct; 154(10):3502-14.
    View in: PubMed
    Score: 0.006
  92. Russell AP, Lamon S, Boon H, Wada S, G?ller I, Brown EL, Chibalin AV, Zierath JR, Snow RJ, Stepto N, Wadley GD, Akimoto T. Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training. J Physiol. 2013 Sep 15; 591(18):4637-53.
    View in: PubMed
    Score: 0.006
  93. Cansby E, Amrutkar M, Manner?s Holm L, Nerstedt A, Reyahi A, Stenfeldt E, Bor?n J, Carlsson P, Smith U, Zierath JR, Mahlapuu M. Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet. FASEB J. 2013 Sep; 27(9):3660-71.
    View in: PubMed
    Score: 0.006
  94. Jiang LQ, Duque-Guimaraes DE, Machado UF, Zierath JR, Krook A. Altered response of skeletal muscle to IL-6 in type 2 diabetic patients. Diabetes. 2013 Feb; 62(2):355-61.
    View in: PubMed
    Score: 0.006
  95. Kulkarni SS, Salehzadeh F, Fritz T, Zierath JR, Krook A, Osler ME. Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus. Metabolism. 2012 Feb; 61(2):175-85.
    View in: PubMed
    Score: 0.005
  96. Mashili FL, Austin RL, Deshmukh AS, Fritz T, Caidahl K, Bergdahl K, Zierath JR, Chibalin AV, Moller DE, Kharitonenkov A, Krook A. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. Diabetes Metab Res Rev. 2011 Mar; 27(3):286-97.
    View in: PubMed
    Score: 0.005
  97. Egan B, Dowling P, O'Connor PL, Henry M, Meleady P, Zierath JR, O'Gorman DJ. 2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics. 2011 Apr; 11(8):1413-28.
    View in: PubMed
    Score: 0.005
  98. Egan B, Carson BP, Garcia-Roves PM, Chibalin AV, Sarsfield FM, Barron N, McCaffrey N, Moyna NM, Zierath JR, O'Gorman DJ. Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle. J Physiol. 2010 May 15; 588(Pt 10):1779-90.
    View in: PubMed
    Score: 0.005
  99. Cant? C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J. Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab. 2010 Mar 03; 11(3):213-9.
    View in: PubMed
    Score: 0.005
  100. Karlsson HK, Chibalin AV, Koistinen HA, Yang J, Koumanov F, Wallberg-Henriksson H, Zierath JR, Holman GD. Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes. 2009 Apr; 58(4):847-54.
    View in: PubMed
    Score: 0.005
  101. Kuoppamaa H, Skrobuk P, Sihvo M, Hiukka A, Chibalin AV, Zierath JR, Koistinen HA. Globular adiponectin stimulates glucose transport in type 2 diabetic muscle. Diabetes Metab Res Rev. 2008 Oct; 24(7):554-62.
    View in: PubMed
    Score: 0.004
  102. Benziane B, Burton TJ, Scanlan B, Galuska D, Canny BJ, Chibalin AV, Zierath JR, Stepto NK. Divergent cell signaling after short-term intensified endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Dec; 295(6):E1427-38.
    View in: PubMed
    Score: 0.004
  103. Glund S, Deshmukh A, Long YC, Moller T, Koistinen HA, Caidahl K, Zierath JR, Krook A. Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Diabetes. 2007 Jun; 56(6):1630-7.
    View in: PubMed
    Score: 0.004
  104. Fritz T, Kr?mer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev. 2006 Nov-Dec; 22(6):492-8.
    View in: PubMed
    Score: 0.004
  105. Cant? C, Chibalin AV, Barnes BR, Glund S, Su?rez E, Ryder JW, Palac?n M, Zierath JR, Zorzano A, Gum? A. Neuregulins mediate calcium-induced glucose transport during muscle contraction. J Biol Chem. 2006 Aug 04; 281(31):21690-21697.
    View in: PubMed
    Score: 0.004
  106. Coffey VG, Zhong Z, Shield A, Canny BJ, Chibalin AV, Zierath JR, Hawley JA. Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans. FASEB J. 2006 Jan; 20(1):190-2.
    View in: PubMed
    Score: 0.004
  107. Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK. Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes. 2005 Oct; 54(10):2939-45.
    View in: PubMed
    Score: 0.004
  108. Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J, Laville M, Guillet C, Boirie Y, Wallberg-Henriksson H, Manco M, Calvani M, Castagneto M, Palac?n M, Mingrone G, Zierath JR, Vidal H, Zorzano A. Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6. Diabetes. 2005 Sep; 54(9):2685-93.
    View in: PubMed
    Score: 0.004
  109. Karlsson HK, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H. Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes. 2005 Jun; 54(6):1692-7.
    View in: PubMed
    Score: 0.003
  110. Karlsson HK, Nilsson PA, Nilsson J, Chibalin AV, Zierath JR, Blomstrand E. Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. Am J Physiol Endocrinol Metab. 2004 Jul; 287(1):E1-7.
    View in: PubMed
    Score: 0.003
  111. Al-Khalili L, Chibalin AV, Yu M, Sj?din B, Nyl?n C, Zierath JR, Krook A. MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am J Physiol Cell Physiol. 2004 Jun; 286(6):C1410-6.
    View in: PubMed
    Score: 0.003
  112. Perrini S, Henriksson J, Zierath JR, Widegren U. Exercise-induced protein kinase C isoform-specific activation in human skeletal muscle. Diabetes. 2004 Jan; 53(1):21-4.
    View in: PubMed
    Score: 0.003
  113. Mahlapuu M, Johansson C, Lindgren K, Hj?lm G, Barnes BR, Krook A, Zierath JR, Andersson L, Marklund S. Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E194-200.
    View in: PubMed
    Score: 0.003
  114. Isaksson B, Str?mmer L, Friess H, B?chler MW, Herrington MK, Wang F, Zierath JR, Wallberg-Henriksson H, Larsson J, Permert J. Impaired insulin action on phosphatidylinositol 3-kinase activity and glucose transport in skeletal muscle of pancreatic cancer patients. Pancreas. 2003 Mar; 26(2):173-7.
    View in: PubMed
    Score: 0.003
  115. Tsuchida H, Bj?rnholm M, Fernstr?m M, Galuska D, Johansson P, Wallberg-Henriksson H, Zierath JR, Lake S, Krook A. Gene expression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects. Pflugers Arch. 2002 Oct; 445(1):25-31.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.