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Connection

Mark Klempner to Lyme Disease

This is a "connection" page, showing publications Mark Klempner has written about Lyme Disease.
Connection Strength

5.045
  1. Wang Y, Esquivel R, Flingai S, Schiller ZA, Kern A, Agarwal S, Chu J, Patel A, Sullivan K, Wise MC, Broderick KE, Hu L, Weiner DB, Klempner MS. Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice. J Infect Dis. 2019 03 15; 219(7):1146-1150.
    View in: PubMed
    Score: 0.550
  2. Wang Y, Kern A, Boatright NK, Schiller ZA, Sadowski A, Ejemel M, Souders CA, Reimann KA, Hu L, Thomas WD, Klempner MS. Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes. J Infect Dis. 2016 07 15; 214(2):205-11.
    View in: PubMed
    Score: 0.450
  3. Klempner MS, Baker PJ, Shapiro ED, Marques A, Dattwyler RJ, Halperin JJ, Wormser GP. The reply. Am J Med. 2014 Feb; 127(2):e11-2.
    View in: PubMed
    Score: 0.378
  4. Klempner MS, Baker PJ, Shapiro ED, Marques A, Dattwyler RJ, Halperin JJ, Wormser GP. Treatment trials for post-Lyme disease symptoms revisited. Am J Med. 2013 Aug; 126(8):665-9.
    View in: PubMed
    Score: 0.369
  5. Klempner MS, Halperin JJ, Baker PJ, Shapiro ED, O'Connell S, Fingerle V, Wormser GP. Lyme borreliosis: the challenge of accuracy. Neth J Med. 2012 Jan; 70(1):3-5.
    View in: PubMed
    Score: 0.334
  6. Zhao Z, McCloud B, Fleming R, Klempner MS. Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem Biophys Res Commun. 2007 Jun 29; 358(2):528-33.
    View in: PubMed
    Score: 0.242
  7. Wormser GP, Kaslow R, Tang J, Wade K, Liveris D, Schwartz I, Klempner M. Association between human leukocyte antigen class II alleles and genotype of Borrelia burgdorferi in patients with early lyme disease. J Infect Dis. 2005 Dec 01; 192(11):2020-6.
    View in: PubMed
    Score: 0.218
  8. Klempner MS, Wormser GH, Wade K, Trevino RP, Tang J, Kaslow RA, Schmid C. A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease. J Infect Dis. 2005 Sep 15; 192(6):1010-3.
    View in: PubMed
    Score: 0.214
  9. Zhao Z, Chang H, Trevino RP, Whren K, Bhawan J, Klempner MS. Selective up-regulation of matrix metalloproteinase-9 expression in human erythema migrans skin lesions of acute lyme disease. J Infect Dis. 2003 Oct 15; 188(8):1098-104.
    View in: PubMed
    Score: 0.189
  10. Klempner MS. Controlled trials of antibiotic treatment in patients with post-treatment chronic Lyme disease. Vector Borne Zoonotic Dis. 2002; 2(4):255-63.
    View in: PubMed
    Score: 0.167
  11. Klempner MS, Hu LT, Evans J, Schmid CH, Johnson GM, Trevino RP, Norton D, Levy L, Wall D, McCall J, Kosinski M, Weinstein A. Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease. N Engl J Med. 2001 Jul 12; 345(2):85-92.
    View in: PubMed
    Score: 0.162
  12. Schiller ZA, Rudolph MJ, Toomey JR, Ejemel M, LaRochelle A, Davis SA, Lambert HS, Kern A, Tardo AC, Souders CA, Peterson E, Cannon RD, Ganesa C, Fazio F, Mantis NJ, Cavacini LA, Sullivan-Bolyai J, Hu LT, Embers ME, Klempner MS, Wang Y. Blocking Borrelia burgdorferi transmission from infected ticks to nonhuman primates with a human monoclonal antibody. J Clin Invest. 2021 06 01; 131(11).
    View in: PubMed
    Score: 0.160
  13. Klempner MS, Schmid CH, Hu L, Steere AC, Johnson G, McCloud B, Noring R, Weinstein A. Intralaboratory reliability of serologic and urine testing for Lyme disease. Am J Med. 2001 Feb 15; 110(3):217-9.
    View in: PubMed
    Score: 0.157
  14. Hu LT, Klempner MS. Update on the prevention, diagnosis, and treatment of Lyme disease. Adv Intern Med. 2001; 46:247-75.
    View in: PubMed
    Score: 0.156
  15. Klempner MS, Huber BT. Is it thee or me?--autoimmunity in Lyme disease. Nat Med. 1999 Dec; 5(12):1346-7.
    View in: PubMed
    Score: 0.145
  16. Perides G, Charness ME, Tanner LM, P?ter O, Satz N, Steere AC, Klempner MS. Matrix metalloproteinases in the cerebrospinal fluid of patients with Lyme neuroborreliosis. J Infect Dis. 1998 Feb; 177(2):401-8.
    View in: PubMed
    Score: 0.127
  17. Hu LT, Klempner MS. Host-pathogen interactions in the immunopathogenesis of Lyme disease. J Clin Immunol. 1997 Sep; 17(5):354-65.
    View in: PubMed
    Score: 0.124
  18. Hu LT, Perides G, Tanner LM, Klempner MS. Detection of a 130-kD matrix metalloproteinase in cerebrospinal fluid from a patient with Lyme neuroborreliosis. Clin Infect Dis. 1997 Jun; 24(6):1276-7.
    View in: PubMed
    Score: 0.122
  19. Shandilya S, Kurt Yilmaz N, Sadowski A, Monir E, Schiller ZA, Thomas WD, Klempner MS, Schiffer CA, Wang Y. Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions. J Mol Recognit. 2017 05; 30(5).
    View in: PubMed
    Score: 0.117
  20. Tang KS, Klempner MS, Wormser GP, Marques AR, Alaedini A. Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of Lyme disease but not posttreatment Lyme disease syndrome. Clin Infect Dis. 2015 Dec 01; 61(11):1703-6.
    View in: PubMed
    Score: 0.107
  21. Georgilis K, Noring R, Steere AC, Klempner MS. Neutrophil chemotactic factors in synovial fluids of patients with Lyme disease. Arthritis Rheum. 1991 Jun; 34(6):770-5.
    View in: PubMed
    Score: 0.080
  22. Chandra A, Wormser GP, Klempner MS, Trevino RP, Crow MK, Latov N, Alaedini A. Anti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms. Brain Behav Immun. 2010 Aug; 24(6):1018-24.
    View in: PubMed
    Score: 0.074
  23. Feder HM, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP, Agger WA, Artsob H, Auwaerter P, Dumler JS, Bakken JS, Bockenstedt LK, Green J, Dattwyler RJ, Munoz J, Nadelman RB, Schwartz I, Draper T, McSweegan E, Halperin JJ, Klempner MS, Krause PJ, Mead P, Morshed M, Porwancher R, Radolf JD, Smith RP, Sood S, Weinstein A, Wong SJ, Zemel L. A critical appraisal of "chronic Lyme disease". N Engl J Med. 2007 Oct 04; 357(14):1422-30.
    View in: PubMed
    Score: 0.062
  24. Zhao Z, Fleming R, McCloud B, Klempner MS. CD14 mediates cross talk between mononuclear cells and fibroblasts for upregulation of matrix metalloproteinase 9 by Borrelia burgdorferi. Infect Immun. 2007 Jun; 75(6):3062-9.
    View in: PubMed
    Score: 0.060
  25. Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, Krause PJ, Bakken JS, Strle F, Stanek G, Bockenstedt L, Fish D, Dumler JS, Nadelman RB. The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006 Nov 01; 43(9):1089-134.
    View in: PubMed
    Score: 0.058
  26. Fleming RV, Marques AR, Klempner MS, Schmid CH, Dally LG, Martin DS, Philipp MT. Pre-treatment and post-treatment assessment of the C(6) test in patients with persistent symptoms and a history of Lyme borreliosis. Eur J Clin Microbiol Infect Dis. 2004 Aug; 23(8):615-8.
    View in: PubMed
    Score: 0.050
  27. Lin B, Kidder JM, Noring R, Steere AC, Klempner MS, Hu LT. Differences in synovial fluid levels of matrix metalloproteinases suggest separate mechanisms of pathogenesis in Lyme arthritis before and after antibiotic treatment. J Infect Dis. 2001 Jul 15; 184(2):174-80.
    View in: PubMed
    Score: 0.040
  28. Lin B, Noring R, Steere AC, Klempner MS, Hu LT. Soluble CD14 levels in the serum, synovial fluid, and cerebrospinal fluid of patients with various stages of Lyme disease. J Infect Dis. 2000 Mar; 181(3):1185-8.
    View in: PubMed
    Score: 0.037
  29. Perides G, Tanner-Brown LM, Eskildsen MA, Klempner MS. Borrelia burgdorferi induces matrix metalloproteinases by neural cultures. J Neurosci Res. 1999 Dec 15; 58(6):779-90.
    View in: PubMed
    Score: 0.036
  30. Sigal LH, Zahradnik JM, Lavin P, Patella SJ, Bryant G, Haselby R, Hilton E, Kunkel M, Adler-Klein D, Doherty T, Evans J, Molloy PJ, Seidner AL, Sabetta JR, Simon HJ, Klempner MS, Mays J, Marks D, Malawista SE. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium. N Engl J Med. 1998 Jul 23; 339(4):216-22.
    View in: PubMed
    Score: 0.033
  31. Klempner MS, Noring R, Epstein MP, McCloud B, Hu R, Limentani SA, Rogers RA. Binding of human plasminogen and urokinase-type plasminogen activator to the Lyme disease spirochete, Borrelia burgdorferi. J Infect Dis. 1995 May; 171(5):1258-65.
    View in: PubMed
    Score: 0.026
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.