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Connection

Carol Schrader to Animals

This is a "connection" page, showing publications Carol Schrader has written about Animals.
Connection Strength

0.531
  1. Schrader CE, Williams T, Pechhold K, Linehan EK, Tsuchimoto D, Nakabeppu Y. APE2 Promotes AID-Dependent Somatic Hypermutation in Primary B Cell Cultures That Is Suppressed by APE1. J Immunol. 2023 06 01; 210(11):1804-1814.
    View in: PubMed
    Score: 0.060
  2. Stavnezer J, Schrader CE. Response to comment on "IgH chain class switch recombination: mechanism and regulation". J Immunol. 2015 Mar 01; 194(5):2040.
    View in: PubMed
    Score: 0.034
  3. Stavnezer J, Schrader CE. IgH chain class switch recombination: mechanism and regulation. J Immunol. 2014 Dec 01; 193(11):5370-8.
    View in: PubMed
    Score: 0.034
  4. Guikema JE, Linehan EK, Esa N, Tsuchimoto D, Nakabeppu Y, Woodland RT, Schrader CE. Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells. J Immunol. 2014 Jul 15; 193(2):931-9.
    View in: PubMed
    Score: 0.032
  5. Stavnezer J, Linehan EK, Thompson MR, Habboub G, Ucher AJ, Kadungure T, Tsuchimoto D, Nakabeppu Y, Schrader CE. Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9217-22.
    View in: PubMed
    Score: 0.032
  6. Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J. DNA polymerases ? and ? do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations. DNA Repair (Amst). 2013 Dec; 12(12):1087-93.
    View in: PubMed
    Score: 0.031
  7. Guikema JE, Gerstein RM, Linehan EK, Cloherty EK, Evan-Browning E, Tsuchimoto D, Nakabeppu Y, Schrader CE. Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge. J Immunol. 2011 Feb 15; 186(4):1943-50.
    View in: PubMed
    Score: 0.026
  8. Guikema JE, Stavnezer J, Schrader CE. The role of Apex2 in class-switch recombination of immunoglobulin genes. Int Immunol. 2010 Mar; 22(3):213; author reply 213-4.
    View in: PubMed
    Score: 0.024
  9. Stavnezer J, Guikema JE, Schrader CE. Mechanism and regulation of class switch recombination. Annu Rev Immunol. 2008; 26:261-92.
    View in: PubMed
    Score: 0.021
  10. Guikema JE, Linehan EK, Tsuchimoto D, Nakabeppu Y, Strauss PR, Stavnezer J, Schrader CE. APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. J Exp Med. 2007 Nov 26; 204(12):3017-26.
    View in: PubMed
    Score: 0.021
  11. Schrader CE, Guikema JE, Linehan EK, Selsing E, Stavnezer J. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J Immunol. 2007 Nov 01; 179(9):6064-71.
    View in: PubMed
    Score: 0.021
  12. Stavnezer J, Schrader CE. Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination. Trends Genet. 2006 Jan; 22(1):23-8.
    View in: PubMed
    Score: 0.018
  13. Schrader CE, Linehan EK, Mochegova SN, Woodland RT, Stavnezer J. Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med. 2005 Aug 15; 202(4):561-8.
    View in: PubMed
    Score: 0.018
  14. Jordano-Raya M, Schrader CE, Ariza RR, Rold?n-Arjona T, C?rdoba-Ca?ero D. Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases. Nucleic Acids Res. 2025 Jan 07; 53(1).
    View in: PubMed
    Score: 0.017
  15. Schrader CE, Vardo J, Linehan E, Twarog MZ, Niedernhofer LJ, Hoeijmakers JH, Stavnezer J. Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions. J Exp Med. 2004 Aug 02; 200(3):321-30.
    View in: PubMed
    Score: 0.016
  16. Schrader CE, Bradley SP, Vardo J, Mochegova SN, Flanagan E, Stavnezer J. Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination. EMBO J. 2003 Nov 03; 22(21):5893-903.
    View in: PubMed
    Score: 0.016
  17. Schrader CE, Vardo J, Stavnezer J. Mlh1 can function in antibody class switch recombination independently of Msh2. J Exp Med. 2003 May 19; 197(10):1377-83.
    View in: PubMed
    Score: 0.015
  18. Schrader CE, Vardo J, Stavnezer J. Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J Exp Med. 2002 Feb 04; 195(3):367-73.
    View in: PubMed
    Score: 0.014
  19. Kadungure T, Ucher AJ, Linehan EK, Schrader CE, Stavnezer J. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination. PLoS One. 2015; 10(8):e0134397.
    View in: PubMed
    Score: 0.009
  20. Khair L, Baker RE, Linehan EK, Schrader CE, Stavnezer J. Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells. PLoS Genet. 2015 Aug; 11(8):e1005438.
    View in: PubMed
    Score: 0.009
  21. Ucher AJ, Ranjit S, Kadungure T, Linehan EK, Khair L, Xie E, Limauro J, Rauch KS, Schrader CE, Stavnezer J. Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching. J Immunol. 2014 Aug 01; 193(3):1440-50.
    View in: PubMed
    Score: 0.008
  22. Khair L, Guikema JE, Linehan EK, Ucher AJ, Leus NG, Ogilvie C, Lou Z, Schrader CE, Stavnezer J. ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination. J Immunol. 2014 May 15; 192(10):4887-96.
    View in: PubMed
    Score: 0.008
  23. Ucher AJ, Linehan EK, Teebor GW, Schrader CE, Stavnezer J. The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells. PLoS One. 2012; 7(4):e36061.
    View in: PubMed
    Score: 0.007
  24. Ranjit S, Khair L, Linehan EK, Ucher AJ, Chakrabarti M, Schrader CE, Stavnezer J. AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected]. J Immunol. 2011 Sep 01; 187(5):2464-75.
    View in: PubMed
    Score: 0.007
  25. Pei DS, Yang XJ, Liu W, Guikema JE, Schrader CE, Strauss PR. A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. Nucleic Acids Res. 2011 Apr; 39(8):3156-65.
    View in: PubMed
    Score: 0.006
  26. Guikema JE, Schrader CE, Brodsky MH, Linehan EK, Richards A, El Falaky N, Li DH, Sluss HK, Szomolanyi-Tsuda E, Stavnezer J. p53 represses class switch recombination to IgG2a through its antioxidant function. J Immunol. 2010 Jun 01; 184(11):6177-87.
    View in: PubMed
    Score: 0.006
  27. Eccleston J, Schrader CE, Yuan K, Stavnezer J, Selsing E. Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats. J Immunol. 2009 Jul 15; 183(2):1222-8.
    View in: PubMed
    Score: 0.006
  28. Guikema JE, Schrader CE, Leus NG, Ucher A, Linehan EK, Werling U, Edelmann W, Stavnezer J. Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching. J Immunol. 2008 Dec 15; 181(12):8450-9.
    View in: PubMed
    Score: 0.006
  29. Min IM, Rothlein LR, Schrader CE, Stavnezer J, Selsing E. Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2. J Exp Med. 2005 Jun 20; 201(12):1885-90.
    View in: PubMed
    Score: 0.004
  30. Min IM, Schrader CE, Vardo J, Luby TM, D'Avirro N, Stavnezer J, Selsing E. The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2. Immunity. 2003 Oct; 19(4):515-24.
    View in: PubMed
    Score: 0.004
  31. Drouin EE, Schrader CE, Stavnezer J, Hansen U. The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA. J Immunol. 2002 Mar 15; 168(6):2847-56.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.