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Connection

Kenneth Rock to Peptides

This is a "connection" page, showing publications Kenneth Rock has written about Peptides.
Connection Strength

2.003
  1. Farf?n-Arribas DJ, Stern LJ, Rock KL. Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16998-7003.
    View in: PubMed
    Score: 0.315
  2. York IA, Brehm MA, Zendzian S, Towne CF, Rock KL. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9202-7.
    View in: PubMed
    Score: 0.203
  3. York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL. The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity. 2003 Mar; 18(3):429-40.
    View in: PubMed
    Score: 0.162
  4. Goldberg AL, Cascio P, Saric T, Rock KL. The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol Immunol. 2002 Oct; 39(3-4):147-64.
    View in: PubMed
    Score: 0.157
  5. Colbert JD, Rock KL. How a tailor achieves the perfect fit. J Biol Chem. 2020 05 22; 295(21):7211-7212.
    View in: PubMed
    Score: 0.134
  6. Rock KL, Goldberg AL. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol. 1999; 17:739-79.
    View in: PubMed
    Score: 0.121
  7. Kincaid EZ, Murata S, Tanaka K, Rock KL. Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells. Nat Immunol. 2016 08; 17(8):938-45.
    View in: PubMed
    Score: 0.102
  8. Rock KL, Farf?n-Arribas DJ, Colbert JD, Goldberg AL. Re-examining class-I presentation and the DRiP hypothesis. Trends Immunol. 2014 Apr; 35(4):144-52.
    View in: PubMed
    Score: 0.087
  9. Rock KL, Fleischacker C, Gamble S. Peptide-priming of cytolytic T cell immunity in vivo using beta 2-microglobulin as an adjuvant. J Immunol. 1993 Feb 15; 150(4):1244-52.
    View in: PubMed
    Score: 0.081
  10. Falo LD, Colarusso LJ, Benacerraf B, Rock KL. Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1992 Sep 01; 89(17):8347-50.
    View in: PubMed
    Score: 0.078
  11. Menzies FM, Hourez R, Imarisio S, Raspe M, Sadiq O, Chandraratna D, O'Kane C, Rock KL, Reits E, Goldberg AL, Rubinsztein DC. Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. Hum Mol Genet. 2010 Dec 01; 19(23):4573-86.
    View in: PubMed
    Score: 0.068
  12. Georgiadou D, Hearn A, Evnouchidou I, Chroni A, Leondiadis L, York IA, Rock KL, Stratikos E. Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J Immunol. 2010 Aug 01; 185(3):1584-92.
    View in: PubMed
    Score: 0.067
  13. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. J Immunol. 2008 Feb 01; 180(3):1704-12.
    View in: PubMed
    Score: 0.057
  14. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol. 2005 Nov 15; 175(10):6605-14.
    View in: PubMed
    Score: 0.049
  15. Falo LD, Sullivan K, Benacerraf B, Mescher MF, Rock KL. Analysis of antigen presentation by metabolically inactive accessory cells and their isolated membranes. Proc Natl Acad Sci U S A. 1985 Oct; 82(19):6647-51.
    View in: PubMed
    Score: 0.048
  16. Pozzi LA, Maciaszek JW, Rock KL. Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells. J Immunol. 2005 Aug 15; 175(4):2071-81.
    View in: PubMed
    Score: 0.048
  17. Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL. Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase. J Biol Chem. 2001 Sep 28; 276(39):36474-81.
    View in: PubMed
    Score: 0.036
  18. York IA, Goldberg AL, Mo XY, Rock KL. Proteolysis and class I major histocompatibility complex antigen presentation. Immunol Rev. 1999 Dec; 172:49-66.
    View in: PubMed
    Score: 0.032
  19. Gaczynska M, Rock KL, Goldberg AL. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature. 1993 Sep 16; 365(6443):264-7.
    View in: PubMed
    Score: 0.021
  20. Vidard L, Rock KL, Benacerraf B. Heterogeneity in antigen processing by different types of antigen-presenting cells. Effect of cell culture on antigen processing ability. J Immunol. 1992 Sep 15; 149(6):1905-11.
    View in: PubMed
    Score: 0.020
  21. Vidard L, Rock KL, Benacerraf B. The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors. J Immunol. 1991 Sep 15; 147(6):1786-91.
    View in: PubMed
    Score: 0.018
  22. Benacerraf B, Michalek MT, Dang LH, Rock KL. The importance of antigen processing in determinant selection and of the cell membrane as a reservoir of processed antigen. Cold Spring Harb Symp Quant Biol. 1989; 54 Pt 1:293-8.
    View in: PubMed
    Score: 0.015
  23. Rock KL. Self antigenic mimicry and Ir gene control of T cell responsiveness--a commentary. J Mol Cell Immunol. 1985; 2(2):80-1.
    View in: PubMed
    Score: 0.011
  24. Rock KL, Benacerraf B, Abbas AK. Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J Exp Med. 1984 Oct 01; 160(4):1102-13.
    View in: PubMed
    Score: 0.011
  25. Benacerraf B, Rock KL. The interaction between class II MHC molecules and antigens as a basis for Ir gene specificity. Ann Immunol (Paris). 1984 May-Jun; 135C(3):386-9.
    View in: PubMed
    Score: 0.011
  26. Rock KL, Benacerraf B. Selective modification of a private I-A allo-stimulating determinant(s) upon association of antigen with an antigen-presenting cell. J Exp Med. 1984 Apr 01; 159(4):1238-52.
    View in: PubMed
    Score: 0.011
  27. Rock KL, Benacerraf B. Inhibition of antigen-specific T lymphocyte activation by structurally related Ir gene-controlled polymers. Evidence of specific competition for accessory cell antigen presentation. J Exp Med. 1983 May 01; 157(5):1618-34.
    View in: PubMed
    Score: 0.010
  28. Rock KL, Benacerraf B. MHC-restricted T cell activation: analysis with T cell hybridomas. Immunol Rev. 1983; 76:29-57.
    View in: PubMed
    Score: 0.010
  29. Letvin NL, Rock KL, Nepom JT, Gramm CF, Benacerraf B. Antibody responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures: anti-hapten and anti-carrier responses appear to be under separable control. Cell Immunol. 1982 Jul 15; 71(1):89-98.
    View in: PubMed
    Score: 0.010
  30. Cascio P, Hilton C, Kisselev AF, Rock KL, Goldberg AL. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J. 2001 May 15; 20(10):2357-66.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.