Kenneth Rock to Mice
This is a "connection" page, showing publications Kenneth Rock has written about Mice.
Connection Strength
2.204
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Cruz FM, Orellano LAA, Chan A, Rock KL. Alternate MHC I Antigen Presentation Pathways Allow CD8+ T-cell Recognition and Killing of Cancer Cells in the Absence of ?2M or TAP. Cancer Immunol Res. 2025 Jan 09; 13(1):98-108.
Score: 0.092
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Sari G, Dhatchinamoorthy K, Orellano-Ariza L, Ferreira LM, Brehm MA, Rock K. IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas. J Exp Clin Cancer Res. 2024 Oct 02; 43(1):276.
Score: 0.090
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Colbert JD, Cruz FM, Baer CE, Rock KL. Tetraspanin-5-mediated MHC class I clustering is required for optimal CD8 T cell activation. Proc Natl Acad Sci U S A. 2022 10 18; 119(42):e2122188119.
Score: 0.079
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Lai JJ, Cruz FM, Rock KL. Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury. Immunity. 2020 01 14; 52(1):123-135.e6.
Score: 0.065
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Cruz FM, Colbert JD, Rock KL. The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments. EMBO J. 2020 01 15; 39(2):e102020.
Score: 0.065
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Orlowski GM, Sharma S, Colbert JD, Bogyo M, Robertson SA, Kataoka H, Chan FK, Rock KL. Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1? activation. J Leukoc Biol. 2017 07; 102(1):7-17.
Score: 0.053
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Kincaid EZ, Murata S, Tanaka K, Rock KL. Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells. Nat Immunol. 2016 08; 17(8):938-45.
Score: 0.051
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Orlowski GM, Colbert JD, Sharma S, Bogyo M, Robertson SA, Rock KL. Multiple Cathepsins Promote Pro-IL-1? Synthesis and NLRP3-Mediated IL-1? Activation. J Immunol. 2015 Aug 15; 195(4):1685-97.
Score: 0.048
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Karmarkar D, Rock KL. Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response. Immunology. 2013 Dec; 140(4):483-92.
Score: 0.043
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Colbert JD, Farf?n-Arribas DJ, Rock KL. Substrate-induced protein stabilization reveals a predominant contribution from mature proteins to peptides presented on MHC class I. J Immunol. 2013 Dec 01; 191(11):5410-9.
Score: 0.042
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Farf?n-Arribas DJ, Stern LJ, Rock KL. Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16998-7003.
Score: 0.039
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Kono H, Orlowski GM, Patel Z, Rock KL. The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C. J Immunol. 2012 Oct 01; 189(7):3734-40.
Score: 0.039
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Janko M, Ontiveros F, Fitzgerald TJ, Deng A, DeCicco M, Rock KL. IL-1 generated subsequent to radiation-induced tissue injury contributes to the pathogenesis of radiodermatitis. Radiat Res. 2012 Sep; 178(3):166-72.
Score: 0.039
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Kincaid EZ, Che JW, York I, Escobar H, Reyes-Vargas E, Delgado JC, Welsh RM, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rock KL. Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol. 2011 Dec 25; 13(2):129-35.
Score: 0.037
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Kono H, Chen CJ, Ontiveros F, Rock KL. Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest. 2010 Jun; 120(6):1939-49.
Score: 0.033
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Hearn A, York IA, Bishop C, Rock KL. Characterizing the specificity and cooperation of aminopeptidases in the cytosol and endoplasmic reticulum during MHC class I antigen presentation. J Immunol. 2010 May 01; 184(9):4725-32.
Score: 0.033
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Kono H, Karmarkar D, Iwakura Y, Rock KL. Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death. J Immunol. 2010 Apr 15; 184(8):4470-8.
Score: 0.033
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Kawahara M, York IA, Hearn A, Farfan D, Rock KL. Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo. J Immunol. 2009 Nov 15; 183(10):6069-77.
Score: 0.032
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Hernandez MG, Shen L, Rock KL. CD40 on APCs is needed for optimal programming, maintenance, and recall of CD8+ T cell memory even in the absence of CD4+ T cell help. J Immunol. 2008 Apr 01; 180(7):4382-90.
Score: 0.029
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Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. J Immunol. 2008 Feb 01; 180(3):1704-12.
Score: 0.028
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Rock KL, Benacerraf B, Abbas AK. Pillars article: antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. 1984. J Immunol. 2007 Dec 01; 179(11):7194-205.
Score: 0.028
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Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med. 2007 Jul; 13(7):851-6.
Score: 0.027
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Towne CF, York IA, Watkin LB, Lazo JS, Rock KL. Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J Immunol. 2007 Jun 01; 178(11):6923-30.
Score: 0.027
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Hernandez MG, Shen L, Rock KL. CD40-CD40 ligand interaction between dendritic cells and CD8+ T cells is needed to stimulate maximal T cell responses in the absence of CD4+ T cell help. J Immunol. 2007 Mar 01; 178(5):2844-52.
Score: 0.027
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York IA, Bhutani N, Zendzian S, Goldberg AL, Rock KL. Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation. J Immunol. 2006 Aug 01; 177(3):1434-43.
Score: 0.026
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Chen CJ, Shi Y, Hearn A, Fitzgerald K, Golenbock D, Reed G, Akira S, Rock KL. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest. 2006 Aug; 116(8):2262-71.
Score: 0.026
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York IA, Brehm MA, Zendzian S, Towne CF, Rock KL. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9202-7.
Score: 0.025
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Shi Y, Galusha SA, Rock KL. Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model. J Immunol. 2006 Apr 01; 176(7):3905-8.
Score: 0.025
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Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol. 2005 Nov 15; 175(10):6605-14.
Score: 0.024
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Pozzi LA, Maciaszek JW, Rock KL. Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells. J Immunol. 2005 Aug 15; 175(4):2071-81.
Score: 0.024
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Retter MW, Johnson JC, Peckham DW, Bannink JE, Bangur CS, Dresser K, Cai F, Foy TM, Fanger NA, Fanger GR, Woda B, Rock KL. Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts. Cancer Res. 2005 Jul 15; 65(14):6425-34.
Score: 0.024
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York IA, Grant EP, Dahl AM, Rock KL. A mutant cell with a novel defect in MHC class I quality control. J Immunol. 2005 Jun 01; 174(11):6839-46.
Score: 0.024
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Shen L, Sigal LJ, Boes M, Rock KL. Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo. Immunity. 2004 Aug; 21(2):155-65.
Score: 0.022
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Stolarski AE, Lai JJ, Kim J, Rock KL, Remick D. GENETIC ABLATION OF THE C-TYPE LECTIN RECEPTOR CLEC2D INCREASES PERITONITIS MORTALITY, INFLAMMATION, AND PHYSIOLOGY WITHOUT DIMINISHING ORGAN INJURY. Shock. 2024 Sep 01; 62(3):437-446.
Score: 0.022
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Shen L, Rock KL. Cellular protein is the source of cross-priming antigen in vivo. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):3035-40.
Score: 0.022
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Rock KL. The ins and outs of cross-presentation. Nat Immunol. 2003 Oct; 4(10):941-3.
Score: 0.021
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Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature. 2003 Oct 02; 425(6957):516-21.
Score: 0.021
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York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL. The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity. 2003 Mar; 18(3):429-40.
Score: 0.020
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Goldberg AL, Rock K. Not just research tools--proteasome inhibitors offer therapeutic promise. Nat Med. 2002 Apr; 8(4):338-40.
Score: 0.019
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Shi Y, Rock KL. Cell death releases endogenous adjuvants that selectively enhance immune surveillance of particulate antigens. Eur J Immunol. 2002 01; 32(1):155-62.
Score: 0.019
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Hilton CJ, Dahl AM, Rock KL. Anti-peptide antibody blocks peptide binding to MHC class I molecules in the endoplasmic reticulum. J Immunol. 2001 Mar 15; 166(6):3952-6.
Score: 0.018
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Shi Y, Zheng W, Rock KL. Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses. Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26):14590-5.
Score: 0.017
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Sigal LJ, Rock KL. Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation. J Exp Med. 2000 Oct 16; 192(8):1143-50.
Score: 0.017
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Mo AX, van Lelyveld SF, Craiu A, Rock KL. Sequences that flank subdominant and cryptic epitopes influence the proteolytic generation of MHC class I-presented peptides. J Immunol. 2000 Apr 15; 164(8):4003-10.
Score: 0.017
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Fernandes DM, Baird AM, Berg LJ, Rock KL. A monoclonal antibody reactive with a 40-kDa molecule on fetal thymocytes and tumor cells blocks proliferation and stimulates aggregation and apoptosis. J Immunol. 1999 Aug 01; 163(3):1306-14.
Score: 0.016
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Sigal LJ, Crotty S, Andino R, Rock KL. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature. 1999 Mar 04; 398(6722):77-80.
Score: 0.015
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Sigal LJ, Reiser H, Rock KL. The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo. J Immunol. 1998 Sep 15; 161(6):2740-5.
Score: 0.015
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Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem. 1997 May 16; 272(20):13437-45.
Score: 0.014
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Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol. 1997 Mar 15; 158(6):2723-30.
Score: 0.013
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Michalek MT, Grant EP, Rock KL. Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation. J Immunol. 1996 Jul 15; 157(2):617-24.
Score: 0.013
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Rock KL, Clark K. Analysis of the role of MHC class II presentation in the stimulation of cytotoxic T lymphocytes by antigens targeted into the exogenous antigen-MHC class I presentation pathway. J Immunol. 1996 May 15; 156(10):3721-6.
Score: 0.013
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Ersching J, Vasconcelos JR, Ferreira CP, Caetano BC, Machado AV, Bruna-Romero O, Baron MA, Ferreira LR, Cunha-Neto E, Rock KL, Gazzinelli RT, Rodrigues MM. The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi. PLoS Pathog. 2016 04; 12(4):e1005593.
Score: 0.013
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Vidard L, Kovacsovics-Bankowski M, Kraeft SK, Chen LB, Benacerraf B, Rock KL. Analysis of MHC class II presentation of particulate antigens of B lymphocytes. J Immunol. 1996 Apr 15; 156(8):2809-18.
Score: 0.013
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Grant EP, Michalek MT, Goldberg AL, Rock KL. Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation. J Immunol. 1995 Oct 15; 155(8):3750-8.
Score: 0.012
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Falo LD, Kovacsovics-Bankowski M, Thompson K, Rock KL. Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity. Nat Med. 1995 Jul; 1(7):649-53.
Score: 0.012
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Bamezai A, Rock KL. Overexpressed Ly-6A.2 mediates cell-cell adhesion by binding a ligand expressed on lymphoid cells. Proc Natl Acad Sci U S A. 1995 May 09; 92(10):4294-8.
Score: 0.012
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Bamezai A, Palliser D, Berezovskaya A, McGrew J, Higgins K, Lacy E, Rock KL. Regulated expression of Ly-6A.2 is important for T cell development. J Immunol. 1995 May 01; 154(9):4233-9.
Score: 0.012
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Kovacsovics-Bankowski M, Rock KL. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 1995 Jan 13; 267(5195):243-6.
Score: 0.011
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Kovacsovics-Bankowski M, Rock KL. Presentation of exogenous antigens by macrophages: analysis of major histocompatibility complex class I and II presentation and regulation by cytokines. Eur J Immunol. 1994 Oct; 24(10):2421-8.
Score: 0.011
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Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 1994 Sep 09; 78(5):761-71.
Score: 0.011
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Pinto VB, Rock KL. Extracellular matrix-induced stimulation of a CD4-8- thymic T cell line. Cell Immunol. 1994 Apr 15; 155(1):144-55.
Score: 0.011
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Michalek MT, Grant EP, Gramm C, Goldberg AL, Rock KL. A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation. Nature. 1993 Jun 10; 363(6429):552-4.
Score: 0.010
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Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):4942-6.
Score: 0.010
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Dang LH, Lien LL, Benacerraf B, Rock KL. A mutant antigen-presenting cell defective in antigen presentation expresses class II MHC molecules with an altered conformation. J Immunol. 1993 May 15; 150(10):4206-17.
Score: 0.010
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Rock KL, Fleischacker C, Gamble S. Peptide-priming of cytolytic T cell immunity in vivo using beta 2-microglobulin as an adjuvant. J Immunol. 1993 Feb 15; 150(4):1244-52.
Score: 0.010
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Rock KL, Rothstein L, Gamble S, Fleischacker C. Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules. J Immunol. 1993 Jan 15; 150(2):438-46.
Score: 0.010
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Rock KL, Rothstein L, Benacerraf B. Analysis of the association of peptides of optimal length to class I molecules on the surface of cells. Proc Natl Acad Sci U S A. 1992 Oct 01; 89(19):8918-22.
Score: 0.010
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Falo LD, Colarusso LJ, Benacerraf B, Rock KL. Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1992 Sep 01; 89(17):8347-50.
Score: 0.010
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Rock KL, Rothstein L, Fleischacker C, Gamble S. Inhibition of class I and class II MHC-restricted antigen presentation by cytotoxic T lymphocytes specific for an exogenous antigen. J Immunol. 1992 May 15; 148(10):3028-33.
Score: 0.010
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Rock KL, Rothstein L, Gamble S, Gramm C, Benacerraf B. Chemical cross-linking of class I molecules on cells creates receptive peptide binding sites. J Immunol. 1992 Mar 01; 148(5):1451-7.
Score: 0.009
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Michalek MT, Benacerraf B, Rock KL. The class II MHC-restricted presentation of endogenously synthesized ovalbumin displays clonal variation, requires endosomal/lysosomal processing, and is up-regulated by heat shock. J Immunol. 1992 Feb 15; 148(4):1016-24.
Score: 0.009
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Bamezai A, Goldmacher VS, Rock KL. Internalization of glycosyl-phosphatidylinositol (GPI)-anchored lymphocyte proteins. II. GPI-anchored and transmembrane molecules internalize through distinct pathways. Eur J Immunol. 1992 Jan; 22(1):15-21.
Score: 0.009
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Grant EP, Rock KL. MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo. J Immunol. 1992 Jan 01; 148(1):13-8.
Score: 0.009
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Jiang Z, Piao D, Bartels KE, Holyoak GR, Ritchey JW, Ownby CL, Rock K, Slobodov G. Transrectal ultrasound-integrated spectral optical tomography of hypoxic progression of a regressing tumor in a canine prostate. Technol Cancer Res Treat. 2011 Dec; 10(6):519-31.
Score: 0.009
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Bamezai A, Rock KL. Effect of ras-activation on the expression of glycosyl-phosphatidylinositol-anchored proteins on the plasma membrane. Oncogene. 1991 Aug; 6(8):1445-51.
Score: 0.009
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Pinto VB, Rock KL. Characterization of the proliferative response of a CD4-8- thymic T lymphoma cell line to stimulation by thymic cellular elements. J Immunol. 1991 Jul 01; 147(1):42-9.
Score: 0.009
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Rock KL, Gamble S, Rothstein L, Gramm C, Benacerraf B. Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface. Cell. 1991 May 17; 65(4):611-20.
Score: 0.009
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Dang LH, Rock KL. Stimulation of B lymphocytes through surface Ig receptors induces LFA-1 and ICAM-1-dependent adhesion. J Immunol. 1991 May 15; 146(10):3273-9.
Score: 0.009
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McGrew JT, Rock KL. Isolation, expression, and sequence of the TAP/Ly-6A.2 chromosomal gene. J Immunol. 1991 May 15; 146(10):3633-8.
Score: 0.009
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Rock KL, Gramm C, Benacerraf B. Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4200-4.
Score: 0.009
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Rock KL, Gamble S, Rothstein L, Benacerraf B. Reassociation with beta 2-microglobulin is necessary for Db class I major histocompatibility complex binding of an exogenous influenza peptide. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):301-4.
Score: 0.009
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Rock KL, Rothstein LE, Gamble SR, Benacerraf B. Reassociation with beta 2-microglobulin is necessary for Kb class I major histocompatibility complex binding of exogenous peptides. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7517-21.
Score: 0.009
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Menzies FM, Hourez R, Imarisio S, Raspe M, Sadiq O, Chandraratna D, O'Kane C, Rock KL, Reits E, Goldberg AL, Rubinsztein DC. Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. Hum Mol Genet. 2010 Dec 01; 19(23):4573-86.
Score: 0.008
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Rock KL, Gamble S, Rothstein L. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science. 1990 Aug 24; 249(4971):918-21.
Score: 0.008
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Rock KL, Rothstein L, Gamble S. Generation of class I MHC-restricted T-T hybridomas. J Immunol. 1990 Aug 01; 145(3):804-11.
Score: 0.008
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Dang LH, Michalek MT, Takei F, Benaceraff B, Rock KL. Role of ICAM-1 in antigen presentation demonstrated by ICAM-1 defective mutants. J Immunol. 1990 Jun 01; 144(11):4082-91.
Score: 0.008
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Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nu?ez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010 Apr 29; 464(7293):1357-61.
Score: 0.008
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Bamezai A, Goldmacher V, Reiser H, Rock KL. Internalization of phosphatidylinositol-anchored lymphocyte proteins. I. Documentation and potential significance for T cell stimulation. J Immunol. 1989 Nov 15; 143(10):3107-16.
Score: 0.008
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Rock KL, Reiser H, Bamezai A, McGrew J, Benacerraf B. The LY-6 locus: a multigene family encoding phosphatidylinositol-anchored membrane proteins concerned with T-cell activation. Immunol Rev. 1989 Oct; 111:195-224.
Score: 0.008
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Michalek MT, Benacerraf B, Rock KL. Two genetically identical antigen-presenting cell clones display heterogeneity in antigen processing. Proc Natl Acad Sci U S A. 1989 May; 86(9):3316-20.
Score: 0.008
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Bamezai A, Reiser H, Rock KL. T cell receptor/CD3 negative variants are unresponsive to stimulation through the Ly-6 encoded molecule, TAP. J Immunol. 1988 Sep 01; 141(5):1423-8.
Score: 0.007
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Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008 Aug; 9(8):847-56.
Score: 0.007
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Reiser H, Coligan J, Palmer E, Benacerraf B, Rock KL. Cloning and expression of a cDNA for the T-cell-activating protein TAP. Proc Natl Acad Sci U S A. 1988 Apr; 85(7):2255-9.
Score: 0.007
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Yeh ET, Reiser H, Bamezai A, Rock KL. TAP transcription and phosphatidylinositol linkage mutants are defective in activation through the T cell receptor. Cell. 1988 Mar 11; 52(5):665-74.
Score: 0.007
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Reiser H, Yeh ET, Coligan J, Benacerraf B, Rock KL. Structure and function of the TAP protein and related Ly-6-linked molecules. Year Immunol. 1988; 3:80-8.
Score: 0.007
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Falo LD, Benacerraf B, Rothstein L, Rock KL. Cerulenin is a potent inhibitor of antigen processing by antigen-presenting cells. J Immunol. 1987 Dec 15; 139(12):3918-23.
Score: 0.007
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Yeh ET, Reiser H, Daley J, Rock KL. Stimulation of T cells via the TAP molecule, a member in a family of activating proteins encoded in the Ly-6 locus. J Immunol. 1987 Jan 01; 138(1):91-7.
Score: 0.007
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Falo LD, Haber SI, Herrmann S, Benacerraf B, Rock KL. Characterization of antigen association with accessory cells: specific removal of processed antigens from the cell surface by phospholipases. Proc Natl Acad Sci U S A. 1987 Jan; 84(2):522-6.
Score: 0.007
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Yeh ET, Reiser H, Benacerraf B, Rock KL. T cell-activating protein on murine lymphocytes. Fed Proc. 1986 Dec; 45(13):2991-4.
Score: 0.007
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Rock KL, Haber SI, Liano D, Benacerraf B, Abbas AK. Antigen presentation by hapten-specific B lymphocytes. III. Analysis of the immunoglobulin-dependent pathway of antigen presentation to interleukin 1-dependent T lymphocytes. Eur J Immunol. 1986 Nov; 16(11):1407-12.
Score: 0.007
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Yeh ET, Reiser H, Benacerraf B, Rock KL. Expression of T-cell-activating protein in peripheral lymphocyte subsets. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7424-8.
Score: 0.006
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Yeh ET, Reiser H, Benacerraf B, Rock KL. The expression, function, and ontogeny of a novel T cell-activating protein, TAP, in the thymus. J Immunol. 1986 Aug 15; 137(4):1232-8.
Score: 0.006
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Reiser H, Yeh ET, Gramm CF, Benacerraf B, Rock KL. Gene encoding T-cell-activating protein TAP maps to the Ly-6 locus. Proc Natl Acad Sci U S A. 1986 May; 83(9):2954-8.
Score: 0.006
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Rock KL, Yeh ET, Gramm CF, Haber SI, Reiser H, Benacerraf B. TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. J Exp Med. 1986 Feb 01; 163(2):315-33.
Score: 0.006
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Abbas AK, Haber S, Rock KL. Antigen presentation by hapten-specific B lymphocytes. II. Specificity and properties of antigen-presenting B lymphocytes, and function of immunoglobulin receptors. J Immunol. 1985 Sep; 135(3):1661-7.
Score: 0.006
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Rock KL. Self antigenic mimicry and Ir gene control of T cell responsiveness--a commentary. J Mol Cell Immunol. 1985; 2(2):80-1.
Score: 0.006
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Rock KL, Benacerraf B. Inhibition of antigen-specific T lymphocyte activation by structurally related Ir gene-controlled polymers. II. Competitive inhibition of I-E-restricted, antigen-specific T cell responses. J Exp Med. 1984 Dec 01; 160(6):1864-79.
Score: 0.006
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Rock KL, Benacerraf B, Abbas AK. Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J Exp Med. 1984 Oct 01; 160(4):1102-13.
Score: 0.006
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Yeh ET, Benacerraf B, Rock KL. Analysis of thymocyte MHC specificity with thymocyte hybridomas. J Exp Med. 1984 Sep 01; 160(3):799-813.
Score: 0.006
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Benacerraf B, Rock KL. The interaction between class II MHC molecules and antigens as a basis for Ir gene specificity. Ann Immunol (Paris). 1984 May-Jun; 135C(3):386-9.
Score: 0.005
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Rock KL, Benacerraf B. Selective modification of a private I-A allo-stimulating determinant(s) upon association of antigen with an antigen-presenting cell. J Exp Med. 1984 Apr 01; 159(4):1238-52.
Score: 0.005
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Rock KL, Benacerraf B. The role of Ia molecules in the activation of T lymphocytes. IV. The basis of the thymocyte IL 1 response and its possible role in the generation of the T cell repertoire. J Immunol. 1984 Apr; 132(4):1654-62.
Score: 0.005
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Rock KL, Benacerraf B. Thymic T cells are driven to expand upon interaction with self-class II major histocompatibility complex gene products on accessory cells. Proc Natl Acad Sci U S A. 1984 Feb; 81(4):1221-4.
Score: 0.005
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Rock KL, Yeh ET, Benacerraf B. Selection of thymocyte MHC restriction specificity in vitro. J Mol Cell Immunol. 1984; 1(5):311-20.
Score: 0.005
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Rock KL, Benacerraf B. Inhibition of antigen-specific T lymphocyte activation by structurally related Ir gene-controlled polymers. Evidence of specific competition for accessory cell antigen presentation. J Exp Med. 1983 May 01; 157(5):1618-34.
Score: 0.005
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Rock KL, Benacerraf B. MHC-restricted T cell activation: analysis with T cell hybridomas. Immunol Rev. 1983; 76:29-57.
Score: 0.005
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Rock KL, Barnes MC, Germain RN, Benacerraf B. The role of Ia molecules in the activation of T lymphocytes. II. Ia-restricted recognition of allo K/D antigens is required for class I MHC-stimulated mixed lymphocyte responses. J Immunol. 1983 Jan; 130(1):457-62.
Score: 0.005
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Rock KL, Benacerraf B. The role of Ia molecules in the activation of T lymphocytes. III. Antigen-specific, Ia-restricted, interleukin 2-producing T cell hybridomas with detectable affinity for the restricting I-A molecule. J Exp Med. 1983 Jan 01; 157(1):359-64.
Score: 0.005
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Saric T, Chang SC, Hattori A, York IA, Markant S, Rock KL, Tsujimoto M, Goldberg AL. An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol. 2002 Dec; 3(12):1169-76.
Score: 0.005
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Rock KL. The role of Ia molecules in the activation of T lymphocytes. I. The activation of an IL 1-dependent IL 2-producing T cell hybridoma by Con A requires an interaction, which is not H-2-restricted, with an Ia-bearing accessory cell. J Immunol. 1982 Oct; 129(4):1360-6.
Score: 0.005
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Cascio P, Hilton C, Kisselev AF, Rock KL, Goldberg AL. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J. 2001 May 15; 20(10):2357-66.
Score: 0.004
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Russell HI, York IA, Rock KL, Monaco JJ. Class II antigen processing defects in two H2d mouse cell lines are caused by point mutations in the H2-DMa gene. Eur J Immunol. 1999 03; 29(3):905-11.
Score: 0.004
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Mandl S, Sigal LJ, Rock KL, Andino R. Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen. Proc Natl Acad Sci U S A. 1998 Jul 07; 95(14):8216-21.
Score: 0.004
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Henderson SC, Berezovskaya A, English A, Palliser D, Rock KL, Bamezai A. CD4+ T cells mature in the absence of MHC class I and class II expression in Ly-6A.2 transgenic mice. J Immunol. 1998 Jul 01; 161(1):175-82.
Score: 0.004
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Mazzaccaro RJ, Gedde M, Jensen ER, van Santen HM, Ploegh HL, Rock KL, Bloom BR. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11786-91.
Score: 0.003
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Lah TT, Hawley M, Rock KL, Goldberg AL. Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages. FEBS Lett. 1995 Apr 17; 363(1-2):85-9.
Score: 0.003
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Van Kaer L, Ashton-Rickardt PG, Eichelberger M, Gaczynska M, Nagashima K, Rock KL, Goldberg AL, Doherty PC, Tonegawa S. Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity. 1994 Oct; 1(7):533-41.
Score: 0.003
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Vidard L, Rock KL, Benacerraf B. Heterogeneity in antigen processing by different types of antigen-presenting cells. Effect of cell culture on antigen processing ability. J Immunol. 1992 Sep 15; 149(6):1905-11.
Score: 0.002
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Vidard L, Rock KL, Couderc J, Mouton D, Benacerral B. Processing and presentation of ovalbumin in mice genetically selected for antibody response. Eur J Immunol. 1992 Aug; 22(8):2165-8.
Score: 0.002
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Vidard L, Rock KL, Benacerraf B. Diversity in MHC class II ovalbumin T cell epitopes generated by distinct proteases. J Immunol. 1992 Jul 15; 149(2):498-504.
Score: 0.002
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Vidard L, Rock KL, Benacerraf B. The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors. J Immunol. 1991 Sep 15; 147(6):1786-91.
Score: 0.002
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Sy MS, Lee SH, Tsurufuji M, Rock KL, Benacerraf B, Finberg R. Two distinct mechanisms regulate the in vivo generation of cytotoxic T cells. J Exp Med. 1982 Sep 01; 156(3):918-23.
Score: 0.001
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Letvin NL, Rock KL, Nepom JT, Gramm CF, Benacerraf B. Antibody responses to trinitrophenyl (TNP)-L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) in microcultures: anti-hapten and anti-carrier responses appear to be under separable control. Cell Immunol. 1982 Jul 15; 71(1):89-98.
Score: 0.001
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Swierkosz JE, Rock K, Marrack P, Kappler JW. The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 products. J Exp Med. 1978 Feb 01; 147(2):554-70.
Score: 0.001