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Connection

Kenneth Rock to Mice, Inbred C57BL

This is a "connection" page, showing publications Kenneth Rock has written about Mice, Inbred C57BL.
Connection Strength

1.817
  1. Cruz FM, Orellano LAA, Chan A, Rock KL. Alternate MHC I Antigen Presentation Pathways Allow CD8+ T-cell Recognition and Killing of Cancer Cells in the Absence of ?2M or TAP. Cancer Immunol Res. 2025 Jan 09; 13(1):98-108.
    View in: PubMed
    Score: 0.142
  2. Stolarski AE, Lai JJ, Kim J, Rock KL, Remick D. GENETIC ABLATION OF THE C-TYPE LECTIN RECEPTOR CLEC2D INCREASES PERITONITIS MORTALITY, INFLAMMATION, AND PHYSIOLOGY WITHOUT DIMINISHING ORGAN INJURY. Shock. 2024 Sep 01; 62(3):437-446.
    View in: PubMed
    Score: 0.136
  3. Lai JJ, Cruz FM, Rock KL. Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury. Immunity. 2020 01 14; 52(1):123-135.e6.
    View in: PubMed
    Score: 0.100
  4. Cruz FM, Colbert JD, Rock KL. The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments. EMBO J. 2020 01 15; 39(2):e102020.
    View in: PubMed
    Score: 0.100
  5. Kincaid EZ, Murata S, Tanaka K, Rock KL. Specialized proteasome subunits have an essential role in the thymic selection of CD8(+) T cells. Nat Immunol. 2016 08; 17(8):938-45.
    View in: PubMed
    Score: 0.078
  6. Kataoka H, Yang K, Rock KL. The xanthine oxidase inhibitor Febuxostat reduces tissue uric acid content and inhibits injury-induced inflammation in the liver and lung. Eur J Pharmacol. 2015 Jan 05; 746:174-9.
    View in: PubMed
    Score: 0.070
  7. Kataoka H, Kono H, Patel Z, Kimura Y, Rock KL. Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses. PLoS One. 2014; 9(8):e104741.
    View in: PubMed
    Score: 0.069
  8. Karmarkar D, Rock KL. Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response. Immunology. 2013 Dec; 140(4):483-92.
    View in: PubMed
    Score: 0.066
  9. Kono H, Orlowski GM, Patel Z, Rock KL. The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C. J Immunol. 2012 Oct 01; 189(7):3734-40.
    View in: PubMed
    Score: 0.060
  10. Janko M, Ontiveros F, Fitzgerald TJ, Deng A, DeCicco M, Rock KL. IL-1 generated subsequent to radiation-induced tissue injury contributes to the pathogenesis of radiodermatitis. Radiat Res. 2012 Sep; 178(3):166-72.
    View in: PubMed
    Score: 0.060
  11. Kincaid EZ, Che JW, York I, Escobar H, Reyes-Vargas E, Delgado JC, Welsh RM, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rock KL. Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nat Immunol. 2011 Dec 25; 13(2):129-35.
    View in: PubMed
    Score: 0.057
  12. Kono H, Chen CJ, Ontiveros F, Rock KL. Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest. 2010 Jun; 120(6):1939-49.
    View in: PubMed
    Score: 0.051
  13. Hearn A, York IA, Bishop C, Rock KL. Characterizing the specificity and cooperation of aminopeptidases in the cytosol and endoplasmic reticulum during MHC class I antigen presentation. J Immunol. 2010 May 01; 184(9):4725-32.
    View in: PubMed
    Score: 0.051
  14. Kono H, Karmarkar D, Iwakura Y, Rock KL. Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death. J Immunol. 2010 Apr 15; 184(8):4470-8.
    View in: PubMed
    Score: 0.051
  15. Towne CF, York IA, Watkin LB, Lazo JS, Rock KL. Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J Immunol. 2007 Jun 01; 178(11):6923-30.
    View in: PubMed
    Score: 0.042
  16. Chen CJ, Shi Y, Hearn A, Fitzgerald K, Golenbock D, Reed G, Akira S, Rock KL. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest. 2006 Aug; 116(8):2262-71.
    View in: PubMed
    Score: 0.040
  17. York IA, Brehm MA, Zendzian S, Towne CF, Rock KL. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9202-7.
    View in: PubMed
    Score: 0.039
  18. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol. 2005 Nov 15; 175(10):6605-14.
    View in: PubMed
    Score: 0.038
  19. Pozzi LA, Maciaszek JW, Rock KL. Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells. J Immunol. 2005 Aug 15; 175(4):2071-81.
    View in: PubMed
    Score: 0.037
  20. Shi Y, Rock KL. Cell death releases endogenous adjuvants that selectively enhance immune surveillance of particulate antigens. Eur J Immunol. 2002 01; 32(1):155-62.
    View in: PubMed
    Score: 0.029
  21. Hilton CJ, Dahl AM, Rock KL. Anti-peptide antibody blocks peptide binding to MHC class I molecules in the endoplasmic reticulum. J Immunol. 2001 Mar 15; 166(6):3952-6.
    View in: PubMed
    Score: 0.027
  22. Shi Y, Zheng W, Rock KL. Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses. Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26):14590-5.
    View in: PubMed
    Score: 0.027
  23. Sigal LJ, Rock KL. Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation. J Exp Med. 2000 Oct 16; 192(8):1143-50.
    View in: PubMed
    Score: 0.026
  24. Fernandes DM, Baird AM, Berg LJ, Rock KL. A monoclonal antibody reactive with a 40-kDa molecule on fetal thymocytes and tumor cells blocks proliferation and stimulates aggregation and apoptosis. J Immunol. 1999 Aug 01; 163(3):1306-14.
    View in: PubMed
    Score: 0.024
  25. Sigal LJ, Crotty S, Andino R, Rock KL. Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature. 1999 Mar 04; 398(6722):77-80.
    View in: PubMed
    Score: 0.024
  26. Sigal LJ, Reiser H, Rock KL. The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo. J Immunol. 1998 Sep 15; 161(6):2740-5.
    View in: PubMed
    Score: 0.023
  27. Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol. 1997 Mar 15; 158(6):2723-30.
    View in: PubMed
    Score: 0.021
  28. Rock KL, Clark K. Analysis of the role of MHC class II presentation in the stimulation of cytotoxic T lymphocytes by antigens targeted into the exogenous antigen-MHC class I presentation pathway. J Immunol. 1996 May 15; 156(10):3721-6.
    View in: PubMed
    Score: 0.019
  29. Ersching J, Vasconcelos JR, Ferreira CP, Caetano BC, Machado AV, Bruna-Romero O, Baron MA, Ferreira LR, Cunha-Neto E, Rock KL, Gazzinelli RT, Rodrigues MM. The Combined Deficiency of Immunoproteasome Subunits Affects Both the Magnitude and Quality of Pathogen- and Genetic Vaccination-Induced CD8+ T Cell Responses to the Human Protozoan Parasite Trypanosoma cruzi. PLoS Pathog. 2016 04; 12(4):e1005593.
    View in: PubMed
    Score: 0.019
  30. Falo LD, Kovacsovics-Bankowski M, Thompson K, Rock KL. Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity. Nat Med. 1995 Jul; 1(7):649-53.
    View in: PubMed
    Score: 0.018
  31. Bamezai A, Rock KL. Overexpressed Ly-6A.2 mediates cell-cell adhesion by binding a ligand expressed on lymphoid cells. Proc Natl Acad Sci U S A. 1995 May 09; 92(10):4294-8.
    View in: PubMed
    Score: 0.018
  32. Kovacsovics-Bankowski M, Rock KL. Presentation of exogenous antigens by macrophages: analysis of major histocompatibility complex class I and II presentation and regulation by cytokines. Eur J Immunol. 1994 Oct; 24(10):2421-8.
    View in: PubMed
    Score: 0.017
  33. Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):4942-6.
    View in: PubMed
    Score: 0.016
  34. Rock KL, Fleischacker C, Gamble S. Peptide-priming of cytolytic T cell immunity in vivo using beta 2-microglobulin as an adjuvant. J Immunol. 1993 Feb 15; 150(4):1244-52.
    View in: PubMed
    Score: 0.016
  35. Rock KL, Rothstein L, Gamble S, Fleischacker C. Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules. J Immunol. 1993 Jan 15; 150(2):438-46.
    View in: PubMed
    Score: 0.015
  36. Rock KL, Rothstein L, Fleischacker C, Gamble S. Inhibition of class I and class II MHC-restricted antigen presentation by cytotoxic T lymphocytes specific for an exogenous antigen. J Immunol. 1992 May 15; 148(10):3028-33.
    View in: PubMed
    Score: 0.015
  37. Rock KL, Rothstein L, Gamble S, Gramm C, Benacerraf B. Chemical cross-linking of class I molecules on cells creates receptive peptide binding sites. J Immunol. 1992 Mar 01; 148(5):1451-7.
    View in: PubMed
    Score: 0.015
  38. Michalek MT, Benacerraf B, Rock KL. The class II MHC-restricted presentation of endogenously synthesized ovalbumin displays clonal variation, requires endosomal/lysosomal processing, and is up-regulated by heat shock. J Immunol. 1992 Feb 15; 148(4):1016-24.
    View in: PubMed
    Score: 0.015
  39. Grant EP, Rock KL. MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo. J Immunol. 1992 Jan 01; 148(1):13-8.
    View in: PubMed
    Score: 0.014
  40. Rock KL, Gamble S, Rothstein L, Gramm C, Benacerraf B. Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface. Cell. 1991 May 17; 65(4):611-20.
    View in: PubMed
    Score: 0.014
  41. Rock KL, Gramm C, Benacerraf B. Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface. Proc Natl Acad Sci U S A. 1991 May 15; 88(10):4200-4.
    View in: PubMed
    Score: 0.014
  42. Rock KL, Rothstein LE, Gamble SR, Benacerraf B. Reassociation with beta 2-microglobulin is necessary for Kb class I major histocompatibility complex binding of exogenous peptides. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7517-21.
    View in: PubMed
    Score: 0.013
  43. Rock KL, Gamble S, Rothstein L. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science. 1990 Aug 24; 249(4971):918-21.
    View in: PubMed
    Score: 0.013
  44. Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nu?ez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010 Apr 29; 464(7293):1357-61.
    View in: PubMed
    Score: 0.013
  45. Bamezai A, Goldmacher V, Reiser H, Rock KL. Internalization of phosphatidylinositol-anchored lymphocyte proteins. I. Documentation and potential significance for T cell stimulation. J Immunol. 1989 Nov 15; 143(10):3107-16.
    View in: PubMed
    Score: 0.012
  46. Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008 Aug; 9(8):847-56.
    View in: PubMed
    Score: 0.011
  47. Yeh ET, Reiser H, Benacerraf B, Rock KL. The expression, function, and ontogeny of a novel T cell-activating protein, TAP, in the thymus. J Immunol. 1986 Aug 15; 137(4):1232-8.
    View in: PubMed
    Score: 0.010
  48. Yeh ET, Benacerraf B, Rock KL. Analysis of thymocyte MHC specificity with thymocyte hybridomas. J Exp Med. 1984 Sep 01; 160(3):799-813.
    View in: PubMed
    Score: 0.009
  49. Rock KL, Benacerraf B. Selective modification of a private I-A allo-stimulating determinant(s) upon association of antigen with an antigen-presenting cell. J Exp Med. 1984 Apr 01; 159(4):1238-52.
    View in: PubMed
    Score: 0.008
  50. Rock KL, Benacerraf B. Inhibition of antigen-specific T lymphocyte activation by structurally related Ir gene-controlled polymers. Evidence of specific competition for accessory cell antigen presentation. J Exp Med. 1983 May 01; 157(5):1618-34.
    View in: PubMed
    Score: 0.008
  51. Mazzaccaro RJ, Gedde M, Jensen ER, van Santen HM, Ploegh HL, Rock KL, Bloom BR. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11786-91.
    View in: PubMed
    Score: 0.005
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.