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Connection

Kenneth Rock to Multienzyme Complexes

This is a "connection" page, showing publications Kenneth Rock has written about Multienzyme Complexes.
Connection Strength

1.854
  1. Rock KL, York IA, Goldberg AL. Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat Immunol. 2004 Jul; 5(7):670-7.
    View in: PubMed
    Score: 0.224
  2. Goldberg AL, Cascio P, Saric T, Rock KL. The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides. Mol Immunol. 2002 Oct; 39(3-4):147-64.
    View in: PubMed
    Score: 0.199
  3. Goldberg AL, Rock K. Not just research tools--proteasome inhibitors offer therapeutic promise. Nat Med. 2002 Apr; 8(4):338-40.
    View in: PubMed
    Score: 0.192
  4. Rock KL, York IA, Saric T, Goldberg AL. Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol. 2002; 80:1-70.
    View in: PubMed
    Score: 0.189
  5. Mo AX, van Lelyveld SF, Craiu A, Rock KL. Sequences that flank subdominant and cryptic epitopes influence the proteolytic generation of MHC class I-presented peptides. J Immunol. 2000 Apr 15; 164(8):4003-10.
    View in: PubMed
    Score: 0.168
  6. Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem. 1997 May 16; 272(20):13437-45.
    View in: PubMed
    Score: 0.137
  7. Gaczynska M, Goldberg AL, Tanaka K, Hendil KB, Rock KL. Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7. J Biol Chem. 1996 Jul 19; 271(29):17275-80.
    View in: PubMed
    Score: 0.129
  8. Goldberg AL, Gaczynska M, Grant E, Michalek M, Rock KL. Functions of the proteasome in antigen presentation. Cold Spring Harb Symp Quant Biol. 1995; 60:479-90.
    View in: PubMed
    Score: 0.116
  9. Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 1994 Sep 09; 78(5):761-71.
    View in: PubMed
    Score: 0.114
  10. York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, Saric T, Goldberg AL, Rock KL. The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity. 2003 Mar; 18(3):429-40.
    View in: PubMed
    Score: 0.051
  11. Mo XY, Cascio P, Lemerise K, Goldberg AL, Rock K. Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides. J Immunol. 1999 Dec 01; 163(11):5851-9.
    View in: PubMed
    Score: 0.041
  12. York IA, Goldberg AL, Mo XY, Rock KL. Proteolysis and class I major histocompatibility complex antigen presentation. Immunol Rev. 1999 Dec; 172:49-66.
    View in: PubMed
    Score: 0.041
  13. Rock KL, Goldberg AL. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol. 1999; 17:739-79.
    View in: PubMed
    Score: 0.038
  14. Beninga J, Rock KL, Goldberg AL. Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase. J Biol Chem. 1998 Jul 24; 273(30):18734-42.
    View in: PubMed
    Score: 0.037
  15. Craiu A, Akopian T, Goldberg A, Rock KL. Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide. Proc Natl Acad Sci U S A. 1997 Sep 30; 94(20):10850-5.
    View in: PubMed
    Score: 0.035
  16. Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol. 1997 Mar 15; 158(6):2723-30.
    View in: PubMed
    Score: 0.034
  17. Kovacsovics-Bankowski M, Rock KL. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 1995 Jan 13; 267(5195):243-6.
    View in: PubMed
    Score: 0.029
  18. Gaczynska M, Rock KL, Spies T, Goldberg AL. Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9213-7.
    View in: PubMed
    Score: 0.029
  19. Gaczynska M, Rock KL, Goldberg AL. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature. 1993 Sep 16; 365(6443):264-7.
    View in: PubMed
    Score: 0.027
  20. Gaczynska M, Rock KL, Goldberg AL. Role of proteasomes in antigen presentation. Enzyme Protein. 1993; 47(4-6):354-69.
    View in: PubMed
    Score: 0.025
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.