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Connection

Kenneth Rock to Cell Line

This is a "connection" page, showing publications Kenneth Rock has written about Cell Line.
Connection Strength

0.869
  1. Farf?n-Arribas DJ, Stern LJ, Rock KL. Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16998-7003.
    View in: PubMed
    Score: 0.074
  2. Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med. 2007 Jul; 13(7):851-6.
    View in: PubMed
    Score: 0.051
  3. Shi Y, Galusha SA, Rock KL. Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model. J Immunol. 2006 Apr 01; 176(7):3905-8.
    View in: PubMed
    Score: 0.047
  4. Towne CF, York IA, Neijssen J, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Neefjes JJ, Rock KL. Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation. J Immunol. 2005 Nov 15; 175(10):6605-14.
    View in: PubMed
    Score: 0.046
  5. York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, Rock KL. The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol. 2002 Dec; 3(12):1177-84.
    View in: PubMed
    Score: 0.037
  6. Shi Y, Rock KL. Cell death releases endogenous adjuvants that selectively enhance immune surveillance of particulate antigens. Eur J Immunol. 2002 01; 32(1):155-62.
    View in: PubMed
    Score: 0.035
  7. Hilton CJ, Dahl AM, Rock KL. Anti-peptide antibody blocks peptide binding to MHC class I molecules in the endoplasmic reticulum. J Immunol. 2001 Mar 15; 166(6):3952-6.
    View in: PubMed
    Score: 0.033
  8. Shi Y, Zheng W, Rock KL. Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses. Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26):14590-5.
    View in: PubMed
    Score: 0.033
  9. Fernandes DM, Vidard L, Rock KL. Characterization of MHC class II-presented peptides generated from an antigen targeted to different endocytic compartments. Eur J Immunol. 2000 Aug; 30(8):2333-43.
    View in: PubMed
    Score: 0.032
  10. Sigal LJ, Reiser H, Rock KL. The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo. J Immunol. 1998 Sep 15; 161(6):2740-5.
    View in: PubMed
    Score: 0.028
  11. Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem. 1997 May 16; 272(20):13437-45.
    View in: PubMed
    Score: 0.025
  12. Shen Z, Reznikoff G, Dranoff G, Rock KL. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. J Immunol. 1997 Mar 15; 158(6):2723-30.
    View in: PubMed
    Score: 0.025
  13. Gaczynska M, Goldberg AL, Tanaka K, Hendil KB, Rock KL. Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7. J Biol Chem. 1996 Jul 19; 271(29):17275-80.
    View in: PubMed
    Score: 0.024
  14. Michalek MT, Grant EP, Rock KL. Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation. J Immunol. 1996 Jul 15; 157(2):617-24.
    View in: PubMed
    Score: 0.024
  15. Vidard L, Kovacsovics-Bankowski M, Kraeft SK, Chen LB, Benacerraf B, Rock KL. Analysis of MHC class II presentation of particulate antigens of B lymphocytes. J Immunol. 1996 Apr 15; 156(8):2809-18.
    View in: PubMed
    Score: 0.024
  16. Grant EP, Michalek MT, Goldberg AL, Rock KL. Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation. J Immunol. 1995 Oct 15; 155(8):3750-8.
    View in: PubMed
    Score: 0.023
  17. Kovacsovics-Bankowski M, Rock KL. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 1995 Jan 13; 267(5195):243-6.
    View in: PubMed
    Score: 0.022
  18. Pinto VB, Rock KL. Extracellular matrix-induced stimulation of a CD4-8- thymic T cell line. Cell Immunol. 1994 Apr 15; 155(1):144-55.
    View in: PubMed
    Score: 0.021
  19. Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):4942-6.
    View in: PubMed
    Score: 0.019
  20. Rock KL, Rothstein L, Benacerraf B. Analysis of the association of peptides of optimal length to class I molecules on the surface of cells. Proc Natl Acad Sci U S A. 1992 Oct 01; 89(19):8918-22.
    View in: PubMed
    Score: 0.019
  21. Bamezai A, Goldmacher VS, Rock KL. Internalization of glycosyl-phosphatidylinositol (GPI)-anchored lymphocyte proteins. II. GPI-anchored and transmembrane molecules internalize through distinct pathways. Eur J Immunol. 1992 Jan; 22(1):15-21.
    View in: PubMed
    Score: 0.018
  22. Bamezai A, Rock KL. Effect of ras-activation on the expression of glycosyl-phosphatidylinositol-anchored proteins on the plasma membrane. Oncogene. 1991 Aug; 6(8):1445-51.
    View in: PubMed
    Score: 0.017
  23. Rock KL, Gamble S, Rothstein L, Gramm C, Benacerraf B. Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface. Cell. 1991 May 17; 65(4):611-20.
    View in: PubMed
    Score: 0.017
  24. Michalek MT, Benacerraf B, Rock KL. Weak base amines can inhibit class I MHC-restricted antigen presentation. J Immunol. 1991 Jan 15; 146(2):449-56.
    View in: PubMed
    Score: 0.016
  25. Rock KL, Gamble S, Rothstein L, Benacerraf B. Reassociation with beta 2-microglobulin is necessary for Db class I major histocompatibility complex binding of an exogenous influenza peptide. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):301-4.
    View in: PubMed
    Score: 0.016
  26. Menzies FM, Hourez R, Imarisio S, Raspe M, Sadiq O, Chandraratna D, O'Kane C, Rock KL, Reits E, Goldberg AL, Rubinsztein DC. Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. Hum Mol Genet. 2010 Dec 01; 19(23):4573-86.
    View in: PubMed
    Score: 0.016
  27. Rock KL, Gamble S, Rothstein L. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science. 1990 Aug 24; 249(4971):918-21.
    View in: PubMed
    Score: 0.016
  28. Georgiadou D, Hearn A, Evnouchidou I, Chroni A, Leondiadis L, York IA, Rock KL, Stratikos E. Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J Immunol. 2010 Aug 01; 185(3):1584-92.
    View in: PubMed
    Score: 0.016
  29. Michalek MT, Benacerraf B, Rock KL. Two genetically identical antigen-presenting cell clones display heterogeneity in antigen processing. Proc Natl Acad Sci U S A. 1989 May; 86(9):3316-20.
    View in: PubMed
    Score: 0.015
  30. Falo LD, Benacerraf B, Rothstein L, Rock KL. Cerulenin is a potent inhibitor of antigen processing by antigen-presenting cells. J Immunol. 1987 Dec 15; 139(12):3918-23.
    View in: PubMed
    Score: 0.013
  31. Reiser H, Coligan J, Benacerraf B, Rock KL. Biosynthesis, glycosylation, and partial N-terminal amino acid sequence of the T-cell-activating protein TAP. Proc Natl Acad Sci U S A. 1987 May; 84(10):3370-4.
    View in: PubMed
    Score: 0.013
  32. Falo LD, Haber SI, Herrmann S, Benacerraf B, Rock KL. Characterization of antigen association with accessory cells: specific removal of processed antigens from the cell surface by phospholipases. Proc Natl Acad Sci U S A. 1987 Jan; 84(2):522-6.
    View in: PubMed
    Score: 0.012
  33. Reiser H, Oettgen H, Yeh ET, Terhorst C, Low MG, Benacerraf B, Rock KL. Structural characterization of the TAP molecule: a phosphatidylinositol-linked glycoprotein distinct from the T cell receptor/T3 complex and Thy-1. Cell. 1986 Nov 07; 47(3):365-70.
    View in: PubMed
    Score: 0.012
  34. Russell HI, York IA, Rock KL, Monaco JJ. Class II antigen processing defects in two H2d mouse cell lines are caused by point mutations in the H2-DMa gene. Eur J Immunol. 1999 03; 29(3):905-11.
    View in: PubMed
    Score: 0.007
  35. Mazzaccaro RJ, Gedde M, Jensen ER, van Santen HM, Ploegh HL, Rock KL, Bloom BR. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11786-91.
    View in: PubMed
    Score: 0.006
  36. Lah TT, Hawley M, Rock KL, Goldberg AL. Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages. FEBS Lett. 1995 Apr 17; 363(1-2):85-9.
    View in: PubMed
    Score: 0.006
  37. Gaczynska M, Rock KL, Spies T, Goldberg AL. Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9213-7.
    View in: PubMed
    Score: 0.005
  38. Gaczynska M, Rock KL, Goldberg AL. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature. 1993 Sep 16; 365(6443):264-7.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.