Michael Heneka to Mice, Transgenic
This is a "connection" page, showing publications Michael Heneka has written about Mice, Transgenic.
Connection Strength
2.446
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Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.
Score: 0.189
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McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.
Score: 0.185
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Heneka MT. ApoE4 makes microglia trem2bling. Neuron. 2023 01 18; 111(2):142-144.
Score: 0.161
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Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.
Score: 0.148
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Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. J Neurochem. 2020 03; 152(6):710-726.
Score: 0.128
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Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Mol Neurobiol. 2015 Apr; 51(2):661-71.
Score: 0.088
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Gaikwad SM, Heneka MT. Studying M1 and M2 states in adult microglia. Methods Mol Biol. 2013; 1041:185-97.
Score: 0.080
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Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 2013 Jan 31; 493(7434):674-8.
Score: 0.080
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Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid ? burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. J Neurosci. 2012 Dec 05; 32(49):17824-9.
Score: 0.080
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Kummer MP, H?lsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. J Neuroimmune Pharmacol. 2012 Mar; 7(1):165-72.
Score: 0.075
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Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, K?nig S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid ? aggregation and plaque formation. Neuron. 2011 Sep 08; 71(5):833-44.
Score: 0.073
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Terwel D, L?schmann YN, Schmidt HH, Sch?ler HR, Cantz T, Heneka MT. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease. J Neurochem. 2011 Jul; 118(1):105-12.
Score: 0.072
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Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson J?, Holtzman DM, Heneka MT. Critical role of astroglial apolipoprotein E and liver X receptor-a expression for microglial A? phagocytosis. J Neurosci. 2011 May 11; 31(19):7049-59.
Score: 0.071
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Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid ? levels in amyloid precursor protein/PS1 transgenic mice. J Neurochem. 2011 Jan; 116(1):43-52.
Score: 0.069
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Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiol Aging. 2012 Feb; 33(2):426.e1-11.
Score: 0.069
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Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6058-63.
Score: 0.066
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Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochem Int. 2010 Nov; 57(4):375-82.
Score: 0.065
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Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006 Feb 01; 26(5):1343-54.
Score: 0.050
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Sch?tz B, Reimann J, Dumitrescu-Ozimek L, Kappes-Horn K, Landreth GE, Sch?rmann B, Zimmer A, Heneka MT. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J Neurosci. 2005 Aug 24; 25(34):7805-12.
Score: 0.048
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Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53.
Score: 0.047
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Eberhard J, Henning L, F?lle L, Kn?pper K, B?hringer J, Graelmann FJ, H?nschke L, Kenzler J, Brosseron F, Heneka MT, Domingos AI, Eyerich S, Lochner M, Weighardt H, Bedner P, Steinh?user C, F?rster I. Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy. Epilepsia. 2025 Feb; 66(2):554-568.
Score: 0.046
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Ferguson CM, Hildebrand S, Godinho BMDC, Buchwald J, Echeverria D, Coles A, Grigorenko A, Vangjeli L, Sousa J, McHugh N, Hassler M, Santarelli F, Heneka MT, Rogaev E, Khvorova A. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimers Dement. 2024 04; 20(4):2632-2652.
Score: 0.043
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Karabag D, Scheiblich H, Griep A, Santarelli F, Schwartz S, Heneka MT, Ising C. Characterizing microglial senescence: Tau as a key player. J Neurochem. 2023 08; 166(3):517-533.
Score: 0.041
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Joshi P, Riffel F, Satoh K, Enomoto M, Qamar S, Scheiblich H, Villacampa N, Kumar S, Theil S, Parhizkar S, Haass C, Heneka MT, Fraser PE, St George-Hyslop P, Walter J. Differential interaction with TREM2 modulates microglial uptake of modified A? species. Glia. 2021 12; 69(12):2917-2932.
Score: 0.036
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Nitsch L, Petzinna S, Zimmermann J, Schneider L, Krauthausen M, Heneka MT, Getts DR, Becker A, M?ller M. Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model. J Neuroinflammation. 2021 Apr 27; 18(1):101.
Score: 0.036
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Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, Biederbick Y, Halle A, Salomoni P, Heneka MT, Capasso M. mTOR-dependent translation amplifies microglia priming in aging mice. J Clin Invest. 2021 01 04; 131(1).
Score: 0.035
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Schr?der N, Schaffrath A, Welter JA, Putzka T, Griep A, Ziegler P, Brandt E, Samer S, Heneka MT, Kaddatz H, Zhan J, Kipp E, Pufe T, Tauber SC, Kipp M, Brandenburg LO. Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease. J Neuroinflammation. 2020 Apr 24; 17(1):131.
Score: 0.033
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Esteve P, Rueda-Carrasco J, In?s Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandon?s ?, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, R?bano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Dom?nguez M, Bovolenta P. Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis. Nat Neurosci. 2019 08; 22(8):1258-1268.
Score: 0.031
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Nitsch L, Zimmermann J, Krauthausen M, Hofer MJ, Saggu R, Petzold GC, Heneka MT, Getts DR, Becker A, Campbell IL, M?ller M. CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model. Mol Neurobiol. 2019 Dec; 56(12):7977-7993.
Score: 0.031
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Unger MS, Marschallinger J, Kaindl J, Klein B, Johnson M, Khundakar AA, Ro?ner S, Heneka MT, Couillard-Despres S, Rockenstein E, Masliah E, Attems J, Aigner L. Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-? plaques: A potential role in shaping plaque pathology? Alzheimers Dement. 2018 08; 14(8):1022-1037.
Score: 0.029
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Zimmermann J, Emrich M, Krauthausen M, Saxe S, Nitsch L, Heneka MT, Campbell IL, M?ller M. IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination. Mol Neurobiol. 2018 02; 55(2):946-957.
Score: 0.026
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Unger MS, Marschallinger J, Kaindl J, H?fling C, Rossner S, Heneka MT, Van der Linden A, Aigner L. Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer's Disease. Mol Neurobiol. 2016 10; 53(8):5796-806.
Score: 0.026
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Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS One. 2015; 10(7):e0132227.
Score: 0.024
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Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J Neurosci. 2014 Jun 25; 34(26):8845-54.
Score: 0.022
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Krauthausen M, Saxe S, Zimmermann J, Emrich M, Heneka MT, M?ller M. CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system. J Neuroinflammation. 2014 Jun 16; 11:109.
Score: 0.022
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Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, M?ller M. CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia. PLoS One. 2013; 8(2):e57307.
Score: 0.020
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Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Jan; 34(1):351-4.
Score: 0.019
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Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, R?be CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid ? peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 01; 188(3):1098-107.
Score: 0.019
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Mildner A, Schlevogt B, Kierdorf K, B?ttcher C, Erny D, Kummer MP, Quinn M, Br?ck W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci. 2011 Aug 03; 31(31):11159-71.
Score: 0.018
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Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, W?llner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid ?-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J. 2011 Jun 01; 30(11):2255-65.
Score: 0.018
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Ambr?e O, Leimer U, Herring A, G?rtz N, Sachser N, Heneka MT, Paulus W, Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. Am J Pathol. 2006 Aug; 169(2):544-52.
Score: 0.013
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Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14.
Score: 0.013