Header Logo

Connection

Gyongyi Szabo to Animals

Back to Details
This is a "connection" page, showing publications Gyongyi Szabo has written about Animals.
Gyongyi Szabo
Connection Strength
3.874
Animals
  1. Brezani V, Joshi RS, Ortega-Ribera M, Nagesh PT, Brezani V, Zivny A, Kurt-Jones EA, Golenbock DT, Szabo G. Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer's disease associated with inflammasome activation and ASC speck propagation. J Neuroinflammation. 2025 Jul 15; 22(1):183.
    View in: PubMed
    Score: 0.067
  2. Ortega-Ribera M, Zhuang Y, Babuta M, Brezani V, Joshi RS, Zsengeller Z, Thevkar Nagesh P, Wang Y, Bronson R, Szabo G. A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition. Cell Mol Gastroenterol Hepatol. 2025; 19(4):101446.
    View in: PubMed
    Score: 0.065
  3. Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, Copeland C, Zhuang Y, Wang Y, Cho Y, Joshi R, Brezani V, Hawryluk D, Datta AA, Mehta J, Nasser I, Szabo G. Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis. Gut. 2024 Oct 07; 73(11):1854-1869.
    View in: PubMed
    Score: 0.064
  4. Joshi R, Brezani V, Mey GM, Guix?-Muntet S, Ortega-Ribera M, Zhuang Y, Zivny A, Werneburg S, Gracia-Sancho J, Szabo G. IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease. J Neuroinflammation. 2024 Aug 30; 21(1):212.
    View in: PubMed
    Score: 0.063
  5. Nagesh PT, Cho Y, Zhuang Y, Babuta M, Ortega-Ribera M, Joshi R, Brezani V, Patel A, Datta AA, Brezani V, Hsieh YC, Ramos A, Mehta J, Copeland C, Kanata E, Jiang ZG, Vlachos I, Asara J, Szabo G. In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis. Sci Transl Med. 2024 08 07; 16(759):eadg1915.
    View in: PubMed
    Score: 0.063
  6. Babuta M, Morel C, de Carvalho Ribeiro M, Datta AA, Calenda C, Copeland C, Nasser I, Szabo G. A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis. Hepatol Commun. 2024 07 01; 8(7).
    View in: PubMed
    Score: 0.062
  7. Babuta M, Nagesh PT, Datta AA, Remotti V, Zhuang Y, Mehta J, Lami F, Wang Y, Szabo G. Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1? Axis in the Liver. Cells. 2024 06 01; 13(11).
    View in: PubMed
    Score: 0.062
  8. Zhuang Y, Szabo G. Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known. Hepatology. 2024 07 01; 80(1):E2-E3.
    View in: PubMed
    Score: 0.061
  9. Zhuang Y, Ortega-Ribera M, Thevkar Nagesh P, Joshi R, Huang H, Wang Y, Zivny A, Mehta J, Parikh SM, Szabo G. Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1. Hepatology. 2024 04 01; 79(4):752-767.
    View in: PubMed
    Score: 0.059
  10. de Carvalho Ribeiro M, Cho Y, Mehta J, Wang X, Babuta M, Copeland C, Hussein H, Catalano D, Wang Y, Szabo G. Protective role of cGAS in NASH is related to the maintenance of intestinal homeostasis. Liver Int. 2023 09; 43(9):1937-1949.
    View in: PubMed
    Score: 0.058
  11. de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology. 2023 07 01; 78(1):225-242.
    View in: PubMed
    Score: 0.057
  12. Cho Y, Bukong TN, Tornai D, Babuta M, Vlachos IS, Kanata E, Catalano D, Szabo G. Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcohol-associated hepatitis. J Hepatol. 2023 01; 78(1):28-44.
    View in: PubMed
    Score: 0.055
  13. Morel C, Chowdhary V, Thevkar Nagesh P, Ribeiro M, Hawryluk D, Catalano D, Adorini L, Szabo G. Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice. Liver Int. 2023 01; 43(1):100-114.
    View in: PubMed
    Score: 0.055
  14. Babuta M, Szabo G. Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases. J Leukoc Biol. 2022 01; 111(1):75-92.
    View in: PubMed
    Score: 0.052
  15. Bala S, Ganz M, Babuta M, Zhuang Y, Csak T, Calenda CD, Szabo G. Steatosis, inflammasome upregulation, and fibrosis are attenuated in miR-155 deficient mice in a high fat-cholesterol-sugar diet-induced model of NASH. Lab Invest. 2021 12; 101(12):1540-1549.
    View in: PubMed
    Score: 0.051
  16. Lowe PP, Morel C, Ambade A, Iracheta-Vellve A, Kwiatkowski E, Satishchandran A, Furi I, Cho Y, Gyongyosi B, Catalano D, Lefebvre E, Fischer L, Seyedkazemi S, Schafer DP, Szabo G. Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. J Neuroinflammation. 2020 Oct 09; 17(1):296.
    View in: PubMed
    Score: 0.048
  17. Lowe PP, Cho Y, Tornai D, Coban S, Catalano D, Szabo G. Inhibition of the Inflammasome Signaling Cascade Reduces Alcohol Consumption in Female But Not Male Mice. Alcohol Clin Exp Res. 2020 02; 44(2):567-578.
    View in: PubMed
    Score: 0.046
  18. Babuta M, Furi I, Bala S, Bukong TN, Lowe P, Catalano D, Calenda C, Kodys K, Szabo G. Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease. Hepatology. 2019 12; 70(6):2123-2141.
    View in: PubMed
    Score: 0.044
  19. Ambade A, Lowe P, Kodys K, Catalano D, Gyongyosi B, Cho Y, Iracheta-Vellve A, Adejumo A, Saha B, Calenda C, Mehta J, Lefebvre E, Vig P, Szabo G. Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. Hepatology. 2019 03; 69(3):1105-1121.
    View in: PubMed
    Score: 0.043
  20. Moreno C, Mueller S, Szabo G. Non-invasive diagnosis and biomarkers in alcohol-related liver disease. J Hepatol. 2019 02; 70(2):273-283.
    View in: PubMed
    Score: 0.043
  21. Wang X, de Carvalho Ribeiro M, Iracheta-Vellve A, Lowe P, Ambade A, Satishchandran A, Bukong T, Catalano D, Kodys K, Szabo G. Macrophage-Specific Hypoxia-Inducible Factor-1a Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis. Hepatology. 2019 02; 69(2):545-563.
    View in: PubMed
    Score: 0.043
  22. Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Cho Y, Ambade A, Szabo G. Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression. J Neuroinflammation. 2018 Oct 27; 15(1):298.
    View in: PubMed
    Score: 0.042
  23. Bukong TN, Cho Y, Iracheta-Vellve A, Saha B, Lowe P, Adejumo A, Furi I, Ambade A, Gyongyosi B, Catalano D, Kodys K, Szabo G. Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use. J Hepatol. 2018 Nov; 69(5):1145-1154.
    View in: PubMed
    Score: 0.041
  24. Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G. Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90. Hepatology. 2018 05; 67(5):1986-2000.
    View in: PubMed
    Score: 0.041
  25. Szabo G. Alcoholic Liver Disease Accelerates Early Hepatocellular Cancer in a?Mouse Model. Adv Exp Med Biol. 2018; 1032:71-79.
    View in: PubMed
    Score: 0.040
  26. Iracheta-Vellve A, Szabo G. IL-1a in acetaminophen toxicity: a sterile danger signal. Cell Mol Immunol. 2018 Mar; 15(3):284-285.
    View in: PubMed
    Score: 0.040
  27. Satishchandran A, Ambade A, Rao S, Hsueh YC, Iracheta-Vellve A, Tornai D, Lowe P, Gyongyosi B, Li J, Catalano D, Zhong L, Kodys K, Xie J, Bala S, Gao G, Szabo G. MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and?Patients From Ethanol-Induced Liver Disease. Gastroenterology. 2018 01; 154(1):238-252.e7.
    View in: PubMed
    Score: 0.039
  28. Bala S, Csak T, Kodys K, Catalano D, Ambade A, Furi I, Lowe P, Cho Y, Iracheta-Vellve A, Szabo G. Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease. J Leukoc Biol. 2017 08; 102(2):487-498.
    View in: PubMed
    Score: 0.038
  29. Iracheta-Vellve A, Petrasek J, Gyogyosi B, Bala S, Csak T, Kodys K, Szabo G. Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice. Liver Int. 2017 07; 37(7):968-973.
    View in: PubMed
    Score: 0.038
  30. Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Ambade A, Kodys K, Catalano D, Ward DV, Szabo G. Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. PLoS One. 2017; 12(3):e0174544.
    View in: PubMed
    Score: 0.038
  31. Iracheta-Vellve A, Petrasek J, Gyongyosi B, Satishchandran A, Lowe P, Kodys K, Catalano D, Calenda CD, Kurt-Jones EA, Fitzgerald KA, Szabo G. Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes. J Biol Chem. 2016 Dec 23; 291(52):26794-26805.
    View in: PubMed
    Score: 0.037
  32. Bukong TN, Iracheta-Vellve A, Saha B, Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Catalano D, Kodys K, Szabo G. Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease. Hepatology. 2016 10; 64(4):1057-71.
    View in: PubMed
    Score: 0.036
  33. Bukong TN, Iracheta-Vellve A, Gyongyosi B, Ambade A, Catalano D, Kodys K, Szabo G. Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice. Alcohol Clin Exp Res. 2016 07; 40(7):1524-30.
    View in: PubMed
    Score: 0.036
  34. Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Szabo G. Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. World J Gastroenterol. 2016 Apr 28; 22(16):4091-108.
    View in: PubMed
    Score: 0.036
  35. Tilg H, Moschen AR, Szabo G. Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Hepatology. 2016 09; 64(3):955-65.
    View in: PubMed
    Score: 0.035
  36. Ambade A, Satishchandran A, Szabo G. Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1a activation. Sci Rep. 2016 Feb 18; 6:21340.
    View in: PubMed
    Score: 0.035
  37. Bala S, Csak T, Saha B, Zatsiorsky J, Kodys K, Catalano D, Satishchandran A, Szabo G. The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis. J Hepatol. 2016 06; 64(6):1378-87.
    View in: PubMed
    Score: 0.035
  38. Momen-Heravi F, Saha B, Kodys K, Catalano D, Satishchandran A, Szabo G. Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis. J Transl Med. 2015 Aug 12; 13:261.
    View in: PubMed
    Score: 0.034
  39. Szabo G, Iracheta-Vellve A. Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis. Clin Res Hepatol Gastroenterol. 2015 Sep; 39 Suppl 1:S18-23.
    View in: PubMed
    Score: 0.034
  40. Iracheta-Vellve A, Petrasek J, Satishchandran A, Gyongyosi B, Saha B, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. J Hepatol. 2015 Nov; 63(5):1147-55.
    View in: PubMed
    Score: 0.033
  41. Ganz M, Bukong TN, Csak T, Saha B, Park JK, Ambade A, Kodys K, Szabo G. Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. J Transl Med. 2015 Jun 16; 13:193.
    View in: PubMed
    Score: 0.033
  42. Szabo G, Petrasek J. Inflammasome activation and function in liver disease. Nat Rev Gastroenterol Hepatol. 2015 Jul; 12(7):387-400.
    View in: PubMed
    Score: 0.033
  43. Csak T, Bala S, Lippai D, Kodys K, Catalano D, Iracheta-Vellve A, Szabo G. MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis. PLoS One. 2015; 10(6):e0129251.
    View in: PubMed
    Score: 0.033
  44. Bala S, Csak T, Momen-Heravi F, Lippai D, Kodys K, Catalano D, Satishchandran A, Ambros V, Szabo G. Biodistribution and function of extracellular miRNA-155 in mice. Sci Rep. 2015 May 29; 5:10721.
    View in: PubMed
    Score: 0.033
  45. Momen-Heravi F, Bala S, Kodys K, Szabo G. Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS. Sci Rep. 2015 May 14; 5:9991.
    View in: PubMed
    Score: 0.033
  46. Petrasek J, Iracheta-Vellve A, Saha B, Satishchandran A, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease. J Leukoc Biol. 2015 Aug; 98(2):249-56.
    View in: PubMed
    Score: 0.033
  47. Szabo G, Saha B, Bukong TN. Alcohol and HCV: implications for liver cancer. Adv Exp Med Biol. 2015; 815:197-216.
    View in: PubMed
    Score: 0.032
  48. Szabo G. Gut-liver axis in alcoholic liver disease. Gastroenterology. 2015 Jan; 148(1):30-6.
    View in: PubMed
    Score: 0.032
  49. Lippai D, Bala S, Catalano D, Kodys K, Szabo G. Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice. Alcohol Clin Exp Res. 2014 Aug; 38(8):2217-24.
    View in: PubMed
    Score: 0.031
  50. Csak T, Bala S, Lippai D, Satishchandran A, Catalano D, Kodys K, Szabo G. microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis. Liver Int. 2015 Feb; 35(2):532-41.
    View in: PubMed
    Score: 0.031
  51. Ganz M, Csak T, Szabo G. High fat diet feeding results in gender specific steatohepatitis and inflammasome activation. World J Gastroenterol. 2014 Jul 14; 20(26):8525-34.
    View in: PubMed
    Score: 0.031
  52. Saha B, Szabo G. Innate immune cell networking in hepatitis C virus infection. J Leukoc Biol. 2014 Nov; 96(5):757-66.
    View in: PubMed
    Score: 0.031
  53. Csak T, Pillai A, Ganz M, Lippai D, Petrasek J, Park JK, Kodys K, Dolganiuc A, Kurt-Jones EA, Szabo G. Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis. Liver Int. 2014 Oct; 34(9):1402-13.
    View in: PubMed
    Score: 0.031
  54. Momen-Heravi F, Bala S, Bukong T, Szabo G. Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages. Nanomedicine. 2014 Oct; 10(7):1517-27.
    View in: PubMed
    Score: 0.031
  55. Szabo G, Lippai D. Converging actions of alcohol on liver and brain immune signaling. Int Rev Neurobiol. 2014; 118:359-80.
    View in: PubMed
    Score: 0.030
  56. Petrasek J, Iracheta-Vellve A, Csak T, Satishchandran A, Kodys K, Kurt-Jones EA, Fitzgerald KA, Szabo G. STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. Proc Natl Acad Sci U S A. 2013 Oct 08; 110(41):16544-9.
    View in: PubMed
    Score: 0.030
  57. Lippai D, Bala S, Csak T, Kurt-Jones EA, Szabo G. Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice. PLoS One. 2013; 8(8):e70945.
    View in: PubMed
    Score: 0.029
  58. Szabo G, Bala S. Reply: To PMID 22684891. Hepatology. 2013 Jun; 57(6):2547.
    View in: PubMed
    Score: 0.029
  59. Zhang S, Saha B, Kodys K, Szabo G. IFN-? production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells. J Hepatol. 2013 Sep; 59(3):442-9.
    View in: PubMed
    Score: 0.029
  60. Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G. Alcohol-induced IL-1? in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. J Leukoc Biol. 2013 Jul; 94(1):171-82.
    View in: PubMed
    Score: 0.029
  61. Petrasek J, Csak T, Szabo G. Toll-like receptors in liver disease. Adv Clin Chem. 2013; 59:155-201.
    View in: PubMed
    Score: 0.028
  62. Szabo G, Petrasek J, Bala S. Innate immunity and alcoholic liver disease. Dig Dis. 2012; 30 Suppl 1:55-60.
    View in: PubMed
    Score: 0.028
  63. Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct; 122(10):3476-89.
    View in: PubMed
    Score: 0.028
  64. Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, Ward J, Alao H, Kodys K, Szabo G. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology. 2012 Nov; 56(5):1946-57.
    View in: PubMed
    Score: 0.027
  65. Bala S, Tang A, Catalano D, Petrasek J, Taha O, Kodys K, Szabo G. Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance. J Leukoc Biol. 2012 Sep; 92(3):611-20.
    View in: PubMed
    Score: 0.027
  66. Ward J, Bala S, Petrasek J, Szabo G. Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study. World J Gastroenterol. 2012 Jun 14; 18(22):2798-804.
    View in: PubMed
    Score: 0.027
  67. Szabo G, Sarnow P, Bala S. MicroRNA silencing and the development of novel therapies for liver disease. J Hepatol. 2012 Aug; 57(2):462-6.
    View in: PubMed
    Score: 0.027
  68. Levin I, Petrasek J, Szabo G. The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis. Alcohol Clin Exp Res. 2012 Aug; 36(8):1397-406.
    View in: PubMed
    Score: 0.027
  69. Nath B, Szabo G. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology. 2012 Feb; 55(2):622-33.
    View in: PubMed
    Score: 0.026
  70. Ganz M, Csak T, Nath B, Szabo G. Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver. World J Gastroenterol. 2011 Nov 21; 17(43):4772-8.
    View in: PubMed
    Score: 0.026
  71. Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Szabo G. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology. 2011 Jul; 54(1):133-44.
    View in: PubMed
    Score: 0.025
  72. Csak T, Dolganiuc A, Kodys K, Nath B, Petrasek J, Bala S, Lippai D, Szabo G. Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology. 2011 Jun; 53(6):1917-31.
    View in: PubMed
    Score: 0.025
  73. Nath B, Levin I, Csak T, Petrasek J, Mueller C, Kodys K, Catalano D, Mandrekar P, Szabo G. Hepatocyte-specific hypoxia-inducible factor-1a is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice. Hepatology. 2011 May; 53(5):1526-37.
    View in: PubMed
    Score: 0.025
  74. Szabo G, Bala S, Petrasek J, Gattu A. Gut-liver axis and sensing microbes. Dig Dis. 2010; 28(6):737-44.
    View in: PubMed
    Score: 0.025
  75. Dolganiuc A, Szabo G. Dendritic cells in hepatitis C infection: can they (help) win the battle? J Gastroenterol. 2011 Apr; 46(4):432-47.
    View in: PubMed
    Score: 0.025
  76. Csak T, Velayudham A, Hritz I, Petrasek J, Levin I, Lippai D, Catalano D, Mandrekar P, Dolganiuc A, Kurt-Jones E, Szabo G. Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3):G433-41.
    View in: PubMed
    Score: 0.025
  77. Petrasek J, Dolganiuc A, Csak T, Nath B, Hritz I, Kodys K, Catalano D, Kurt-Jones E, Mandrekar P, Szabo G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology. 2011 Feb; 53(2):649-60.
    View in: PubMed
    Score: 0.025
  78. Bala S, Marcos M, Kodys K, Csak T, Catalano D, Mandrekar P, Szabo G. Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease. J Biol Chem. 2011 Jan 14; 286(2):1436-44.
    View in: PubMed
    Score: 0.024
  79. Petrasek J, Dolganiuc A, Csak T, Kurt-Jones EA, Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology. 2011 Feb; 140(2):697-708.e4.
    View in: PubMed
    Score: 0.024
  80. Szabo G, Bala S. Alcoholic liver disease and the gut-liver axis. World J Gastroenterol. 2010 Mar 21; 16(11):1321-9.
    View in: PubMed
    Score: 0.023
  81. Szabo G, Wands JR, Eken A, Osna NA, Weinman SA, Machida K, Joe Wang H. Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage. Alcohol Clin Exp Res. 2010 Oct; 34(10):1675-86.
    View in: PubMed
    Score: 0.023
  82. Szabo G, Mandrekar P. Focus on: Alcohol and the liver. Alcohol Res Health. 2010; 33(1-2):87-96.
    View in: PubMed
    Score: 0.023
  83. Dolganiuc A, Petrasek J, Kodys K, Catalano D, Mandrekar P, Velayudham A, Szabo G. MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. Alcohol Clin Exp Res. 2009 Oct; 33(10):1704-10.
    View in: PubMed
    Score: 0.022
  84. Nath B, Szabo G. Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity. Semin Liver Dis. 2009 May; 29(2):166-77.
    View in: PubMed
    Score: 0.022
  85. Mandrekar P, Szabo G. Signalling pathways in alcohol-induced liver inflammation. J Hepatol. 2009 Jun; 50(6):1258-66.
    View in: PubMed
    Score: 0.022
  86. Dolganiuc A, Szabo G. In vitro and in vivo models of acute alcohol exposure. World J Gastroenterol. 2009 Mar 14; 15(10):1168-77.
    View in: PubMed
    Score: 0.022
  87. Velayudham A, Dolganiuc A, Ellis M, Petrasek J, Kodys K, Mandrekar P, Szabo G. VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice. Hepatology. 2009 Mar; 49(3):989-97.
    View in: PubMed
    Score: 0.022
  88. Szabo G, Mandrekar P. A recent perspective on alcohol, immunity, and host defense. Alcohol Clin Exp Res. 2009 Feb; 33(2):220-32.
    View in: PubMed
    Score: 0.021
  89. Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G. The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology. 2008 Oct; 48(4):1224-31.
    View in: PubMed
    Score: 0.021
  90. Hritz I, Velayudham A, Dolganiuc A, Kodys K, Mandrekar P, Kurt-Jones E, Szabo G. Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion. Hepatology. 2008 Oct; 48(4):1342-7.
    View in: PubMed
    Score: 0.021
  91. Szabo G, Dolganiuc A. Hepatitis C and innate immunity: recent advances. Clin Liver Dis. 2008 Aug; 12(3):675-92, x.
    View in: PubMed
    Score: 0.021
  92. Dolganiuc A, Szabo G. T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't. J Leukoc Biol. 2008 Sep; 84(3):614-22.
    View in: PubMed
    Score: 0.020
  93. Szabo G, Dolganiuc A. The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity. Crit Rev Immunol. 2008; 28(1):61-94.
    View in: PubMed
    Score: 0.020
  94. Szabo G, Mandrekar P, Dolganiuc A. Innate immune response and hepatic inflammation. Semin Liver Dis. 2007 Nov; 27(4):339-50.
    View in: PubMed
    Score: 0.020
  95. Chang S, Dolganiuc A, Szabo G. Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. J Leukoc Biol. 2007 Sep; 82(3):479-87.
    View in: PubMed
    Score: 0.019
  96. Mandrekar P, Jeliazkova V, Catalano D, Szabo G. Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes. J Immunol. 2007 Jun 15; 178(12):7686-93.
    View in: PubMed
    Score: 0.019
  97. Davis GL, Krawczynski K, Szabo G. Hepatitis C virus infection--pathobiology and implications for new therapeutic options. Dig Dis Sci. 2007 Apr; 52(4):857-75.
    View in: PubMed
    Score: 0.019
  98. Drechsler Y, Dolganiuc A, Norkina O, Romics L, Li W, Kodys K, Bach FH, Mandrekar P, Szabo G. Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes. J Immunol. 2006 Aug 15; 177(4):2592-600.
    View in: PubMed
    Score: 0.018
  99. Szabo G, Dolganiuc A, Mandrekar P. Pattern recognition receptors: a contemporary view on liver diseases. Hepatology. 2006 Aug; 44(2):287-98.
    View in: PubMed
    Score: 0.018
  100. Velayudham A, Hritz I, Dolganiuc A, Mandrekar P, Kurt-Jones E, Szabo G. Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury. J Hepatol. 2006 Dec; 45(6):813-24.
    View in: PubMed
    Score: 0.018
  101. Oak S, Mandrekar P, Catalano D, Kodys K, Szabo G. TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes. J Immunol. 2006 Jun 15; 176(12):7628-35.
    View in: PubMed
    Score: 0.018
  102. Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity. Alcohol Clin Exp Res. 2006 Apr; 30(4):709-19.
    View in: PubMed
    Score: 0.018
  103. Szabo G. Hepatitis C virus NS5A protein--a master regulator? Gastroenterology. 2006 Mar; 130(3):995-9.
    View in: PubMed
    Score: 0.018
  104. Dolganiuc A, Bakis G, Kodys K, Mandrekar P, Szabo G. Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts. Alcohol Clin Exp Res. 2006 Jan; 30(1):76-85.
    View in: PubMed
    Score: 0.017
  105. Szabo G, Velayudham A, Romics L, Mandrekar P. Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. Alcohol Clin Exp Res. 2005 Nov; 29(11 Suppl):140S-145S.
    View in: PubMed
    Score: 0.017
  106. Romics L, Dolganiuc A, Velayudham A, Kodys K, Mandrekar P, Golenbock D, Kurt-Jones E, Szabo G. Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes. J Leukoc Biol. 2005 Dec; 78(6):1255-64.
    View in: PubMed
    Score: 0.017
  107. Mandrekar P, Pruett S, Arteel G, Thiele G, Szabo G. RSA 2004: combined basic research satellite symposium - session two: toll-like receptors and organ damage. Alcohol Clin Exp Res. 2005 Sep; 29(9):1744-8.
    View in: PubMed
    Score: 0.017
  108. Szabo G, Hoek JB, Darley-Usmar V, Hajnoczky G, Knudsen T, Mochly-Rosen D, Zakhari S. RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death. Alcohol Clin Exp Res. 2005 Sep; 29(9):1749-52.
    View in: PubMed
    Score: 0.017
  109. Szabo G, Weinman SA, Gao B, Polyak SJ, Mandrekar P, Thiele GM. RSA 2004: combined basic research satellite symposium - session four: hepatitis virus and alcohol interactions in immunity and liver disease. Alcohol Clin Exp Res. 2005 Sep; 29(9):1753-7.
    View in: PubMed
    Score: 0.017
  110. Romics L, Mandrekar P, Kodys K, Velayudham A, Drechsler Y, Dolganiuc A, Szabo G. Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. Alcohol Clin Exp Res. 2005 Jun; 29(6):1018-26.
    View in: PubMed
    Score: 0.017
  111. Shen H, Liangpunsakul S, Iwakiri Y, Szabo G, Wang H. Immunological mechanisms and emerging therapeutic targets in alcohol-associated liver disease. Cell Mol Immunol. 2025 Oct; 22(10):1190-1204.
    View in: PubMed
    Score: 0.017
  112. Khan MAS, Song BJ, Wang X, Iqbal S, Szabo G, Chang SL. Neutrophil extracellular traps (NETs) and NETosis in alcohol-associated diseases: A systematic review. Alcohol Clin Exp Res (Hoboken). 2025 Apr; 49(4):697-711.
    View in: PubMed
    Score: 0.016
  113. Szabo G, Dolganiuc A. Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection. Immunobiology. 2005; 210(2-4):237-47.
    View in: PubMed
    Score: 0.016
  114. Dolganiuc A, Oak S, Kodys K, Golenbock DT, Finberg RW, Kurt-Jones E, Szabo G. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology. 2004 Nov; 127(5):1513-24.
    View in: PubMed
    Score: 0.016
  115. Romics L, Dolganiuc A, Kodys K, Drechsler Y, Oak S, Velayudham A, Mandrekar P, Szabo G. Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice. Hepatology. 2004 Sep; 40(3):555-64.
    View in: PubMed
    Score: 0.016
  116. Romics L, Kodys K, Dolganiuc A, Graham L, Velayudham A, Mandrekar P, Szabo G. Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver. Hepatology. 2004 Aug; 40(2):376-85.
    View in: PubMed
    Score: 0.016
  117. Taru V, Szabo G, Mehal W, Reiberger T. Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation. J Hepatol. 2024 Nov; 81(5):895-910.
    View in: PubMed
    Score: 0.016
  118. Osna NA, Tikhanovich I, Ortega-Ribera M, Mueller S, Zheng C, Mueller J, Li S, Sakane S, Weber RCG, Kim HY, Lee W, Ganguly S, Kimura Y, Liu X, Dhar D, Diggle K, Brenner DA, Kisseleva T, Attal N, McKillop IH, Chokshi S, Mahato R, Rasineni K, Szabo G, Kharbanda KK. Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression. Biomolecules. 2024 Mar 27; 14(4).
    View in: PubMed
    Score: 0.015
  119. Mandrekar P, Dolganiuc A, Bellerose G, Kodys K, Romics L, Nizamani R, Szabo G. Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation? Alcohol Clin Exp Res. 2002 Nov; 26(11):1609-14.
    View in: PubMed
    Score: 0.014
  120. Thevkar-Nagesh P, Habault J, Voisin M, Ruff SE, Ha S, Ruoff R, Chen X, Rawal S, Zahr T, Szabo G, Rogatsky I, Fisher EA, Garabedian MJ. Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation. PLoS One. 2022; 17(9):e0272986.
    View in: PubMed
    Score: 0.014
  121. Szabo G, Mandrekar P. Ethanol-mediated regulation of transcription factors in immunocompetent cells. Front Biosci. 2002 May 01; 7:a80-9.
    View in: PubMed
    Score: 0.013
  122. Helsley RN, Miyata T, Kadam A, Varadharajan V, Sangwan N, Huang EC, Banerjee R, Brown AL, Fung KK, Massey WJ, Neumann C, Orabi D, Osborn LJ, Schugar RC, McMullen MR, Bellar A, Poulsen KL, Kim A, Pathak V, Mrdjen M, Anderson JT, Willard B, McClain CJ, Mitchell M, McCullough AJ, Radaeva S, Barton B, Szabo G, Dasarathy S, Garcia-Garcia JC, Rotroff DM, Allende DS, Wang Z, Hazen SL, Nagy LE, Brown JM. Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice. Elife. 2022 01 27; 11.
    View in: PubMed
    Score: 0.013
  123. Miyata T, Wu X, Fan X, Huang E, Sanz-Garcia C, Ross CKC, Roychowdhury S, Bellar A, McMullen MR, Dasarathy J, Allende DS, Caballeria J, Sancho-Bru P, McClain CJ, Mitchell M, McCullough AJ, Radaeva S, Barton B, Szabo G, Dasarathy S, Nagy LE. Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans. JCI Insight. 2021 02 22; 6(4).
    View in: PubMed
    Score: 0.012
  124. He Y, Hwang S, Ahmed YA, Feng D, Li N, Ribeiro M, Lafdil F, Kisseleva T, Szabo G, Gao B. Immunopathobiology and therapeutic targets related to cytokines in liver diseases. Cell Mol Immunol. 2021 01; 18(1):18-37.
    View in: PubMed
    Score: 0.012
  125. Pilli VS, Datta A, Afreen S, Catalano D, Szabo G, Majumder R. Hypoxia downregulates protein S expression. Blood. 2018 07 26; 132(4):452-455.
    View in: PubMed
    Score: 0.010
  126. Grander C, Adolph TE, Wieser V, Lowe P, Wrzosek L, Gyongyosi B, Ward DV, Grabherr F, Gerner RR, Pfister A, Enrich B, Ciocan D, Macheiner S, Mayr L, Drach M, Moser P, Moschen AR, Perlemuter G, Szabo G, Cassard AM, Tilg H. Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease. Gut. 2018 05; 67(5):891-901.
    View in: PubMed
    Score: 0.010
  127. Shukla SD, Pruett SB, Szabo G, Arteel GE. Binge ethanol and liver: new molecular developments. Alcohol Clin Exp Res. 2013 Apr; 37(4):550-7.
    View in: PubMed
    Score: 0.007
  128. Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, Boucher EN, Wang Y, Cheslock PS, Knauber M, Olsen DB, Ludmerer SW, Szabo G, Finberg RW, Purcell RH, Lanford RE, Ambrosino DM, Molrine DC, Babcock GJ. Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees. PLoS Pathog. 2012; 8(8):e1002895.
    View in: PubMed
    Score: 0.007
  129. Mandrekar P, Ambade A, Lim A, Szabo G, Catalano D. An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology. 2011 Dec; 54(6):2185-97.
    View in: PubMed
    Score: 0.007
  130. Broering TJ, Garrity KA, Boatright NK, Sloan SE, Sandor F, Thomas WD, Szabo G, Finberg RW, Ambrosino DM, Babcock GJ. Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus. J Virol. 2009 Dec; 83(23):12473-82.
    View in: PubMed
    Score: 0.006
  131. Lau AH, Szabo G, Thomson AW. Antigen-presenting cells under the influence of alcohol. Trends Immunol. 2009 Jan; 30(1):13-22.
    View in: PubMed
    Score: 0.005
  132. Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. Acute and chronic alcohol abuse modulate immunity. Alcohol Clin Exp Res. 2006 Sep; 30(9):1624-31.
    View in: PubMed
    Score: 0.005
  133. Romics L, Szabo G, Coffey JC, Wang JH, Redmond HP. The emerging role of toll-like receptor pathways in surgical diseases. Arch Surg. 2006 Jun; 141(6):595-601.
    View in: PubMed
    Score: 0.004
  134. Crews FT, Bechara R, Brown LA, Guidot DM, Mandrekar P, Oak S, Qin L, Szabo G, Wheeler M, Zou J. Cytokines and alcohol. Alcohol Clin Exp Res. 2006 Apr; 30(4):720-30.
    View in: PubMed
    Score: 0.004
  135. Thiele GM, Szabo G, Kovacs EJ, Bautista AP, Sosa L, Jerrells TR. Modulation of immunity and viral-host interactions by alcohol. Alcohol Clin Exp Res. 2002 Dec; 26(12):1897-908.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.