Lila Gierasch to Humans
This is a "connection" page, showing publications Lila Gierasch has written about Humans.
Connection Strength
0.747
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Gierasch LM. From Rat Tails to Glycoproteostasis: Motivated by Biology, Enabled by Biophysics, and Lucky. J Mol Biol. 2025 06 01; 437(11):169055.
Score: 0.035
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Bhasne K, Bogoian-Mullen A, Clerico EM, Gierasch LM. The Hsc70 system maintains the synaptic SNARE protein SNAP-25 in an assembly-competent state and delays its aggregation. J Biol Chem. 2024 12; 300(12):108001.
Score: 0.034
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Williams RV, Guay KP, Hurlbut Lesk OA, Clerico EM, Hebert DN, Gierasch LM. Insights into the interaction between UGGT, the gatekeeper of folding in the ER, and its partner, the selenoprotein SEP15. Proc Natl Acad Sci U S A. 2024 Aug 20; 121(34):e2315009121.
Score: 0.034
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Nordquist EB, Clerico EM, Chen J, Gierasch LM. Computationally-Aided Modeling of Hsp70-Client Interactions: Past, Present, and Future. J Phys Chem B. 2022 09 15; 126(36):6780-6791.
Score: 0.030
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Powers ET, Gierasch LM. The Proteome Folding Problem and Cellular Proteostasis. J Mol Biol. 2021 10 01; 433(20):167197.
Score: 0.027
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Gierasch LM, Davidson NO, Rye KA, Burlingame AL. The data must be accessible to all. J Biol Chem. 2020 03 27; 295(13):4371.
Score: 0.025
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Gierasch LM. Faster publication advances your science: The three R's. J Biol Chem. 2020 01 10; 295(2):672.
Score: 0.025
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Gierasch LM. Celebrating and cultivating excellent peer review at JBC. J Biol Chem. 2019 09 13; 294(37):13850-13851.
Score: 0.024
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Gierasch LM, DeMartino GN. 2020 Herbert Tabor Early Career Investigator Awards: Call for nominations. J Biol Chem. 2019 09 06; 294(36):13526.
Score: 0.024
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Clerico EM, Meng W, Pozhidaeva A, Bhasne K, Petridis C, Gierasch LM. Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines. Biochem J. 2019 06 14; 476(11):1653-1677.
Score: 0.024
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Gierasch LM, Davidson NO, Rye KA, Burlingame AL. For the sake of science. J Biol Chem. 2019 02 22; 294(8):2976.
Score: 0.023
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Gierasch LM, Davidson NO, Rye KA, Burlingame AL. For the Sake of Science. Mol Cell Proteomics. 2019 03; 18(3):406-407.
Score: 0.023
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Gierasch LM, Guengerich FP. Celebrating the scientific legacy of Herbert Tabor. J Biol Chem. 2019 02 01; 294(5):1635-1637.
Score: 0.023
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Mayer MP, Gierasch LM. Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones. J Biol Chem. 2019 02 08; 294(6):2085-2097.
Score: 0.023
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Meng W, Clerico EM, McArthur N, Gierasch LM. Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):11970-11975.
Score: 0.023
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Thakur AK, Meng W, Gierasch LM. Local and non-local topological information in the denatured state ensemble of a ?-barrel protein. Protein Sci. 2018 12; 27(12):2062-2072.
Score: 0.023
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Gierasch LM. Looking back at the last two years: Coming home to JBC. J Biol Chem. 2018 07 13; 293(28):11254.
Score: 0.022
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Hingorani KS, Metcalf MC, Deming DT, Garman SC, Powers ET, Gierasch LM. Ligand-promoted protein folding by biased kinetic partitioning. Nat Chem Biol. 2017 04; 13(4):369-371.
Score: 0.020
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Gierasch LM. A Loyal Friend of ASBMB and JBC: Howard Schachman, 1918-2016. J Biol Chem. 2016 09 09; 291(37):19724.
Score: 0.020
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Hebert DN, Clerico EM, Gierasch LM. Division of Labor: ER-Resident BiP Co-Chaperones Match Substrates to Fates Based on Specific Binding Sequences. Mol Cell. 2016 09 01; 63(5):721-3.
Score: 0.020
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Gierasch LM. What's in a Name? J Biol Chem. 2016 08 26; 291(35):19208-9.
Score: 0.019
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Clerico EM, Tilitsky JM, Meng W, Gierasch LM. How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions. J Mol Biol. 2015 Apr 10; 427(7):1575-88.
Score: 0.018
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Hingorani KS, Gierasch LM. Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge. Curr Opin Struct Biol. 2014 Feb; 24:81-90.
Score: 0.016
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Gierasch LM, Lynn DG, Schneider JP. The Sixth Peptide Engineering Meeting PEM6, Emory University Conference Center, Atlanta, Georgia, October 2 to 5, 2012. Biopolymers. 2013 Nov; 100(6):vii.
Score: 0.016
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Budyak IL, Zhuravleva A, Gierasch LM. The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of ?-Sheets. J Mol Biol. 2013 Sep 23; 425(18):3522-35.
Score: 0.016
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Gierasch LM, Lynn DG, Schneider J. The Sixth Peptide Engineering Meeting PEM6, Emory University Conference Center, Atlanta, Georgia, October 2 to 5, 2012. Biopolymers. 2012; 98(1):iii.
Score: 0.014
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Krishnan B, Gierasch LM. Dynamic local unfolding in the serpin a-1 antitrypsin provides a mechanism for loop insertion and polymerization. Nat Struct Mol Biol. 2011 Feb; 18(2):222-6.
Score: 0.013
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Gershenson A, Gierasch LM. Protein folding in the cell: challenges and progress. Curr Opin Struct Biol. 2011 Feb; 21(1):32-41.
Score: 0.013
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Gierasch LM. A tribute to the career of a gentle giant of peptide science. Biopolymers. 2008; 90(3):153.
Score: 0.011
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Ignatova Z, Gierasch LM. Chapter 3: A fluorescent window into protein folding and aggregation in cells. Methods Cell Biol. 2008; 89:59-70.
Score: 0.011
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Ignatova Z, Thakur AK, Wetzel R, Gierasch LM. In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence. J Biol Chem. 2007 Dec 14; 282(50):36736-43.
Score: 0.011
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Ignatova Z, Gierasch LM. Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant. Proc Natl Acad Sci U S A. 2006 Sep 05; 103(36):13357-61.
Score: 0.010
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Ignatova Z, Gierasch LM. Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent beta barrel protein. J Biol Chem. 2006 May 05; 281(18):12959-67.
Score: 0.009
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Guay KP, Ke H, Gierasch LM, Gershenson A, Hebert DN. Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types. Methods Mol Biol. 2024; 2750:143-163.
Score: 0.008
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Guay KP, Ke H, Canniff NP, George GT, Eyles SJ, Mariappan M, Contessa JN, Gershenson A, Gierasch LM, Hebert DN. ER chaperones use a protein folding and quality control glyco-code. Mol Cell. 2023 12 21; 83(24):4524-4537.e5.
Score: 0.008
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Ke H, Guay KP, Flotte TR, Gierasch LM, Gershenson A, Hebert DN. Secretion of functional a1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2206103119.
Score: 0.007
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Cleverley RM, Zheng N, Gierasch LM. The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle. J Biol Chem. 2001 Jun 01; 276(22):19327-31.
Score: 0.007
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Adams BM, Ke H, Gierasch LM, Gershenson A, Hebert DN. Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control. J Biol Chem. 2019 12 13; 294(50):18992-19011.
Score: 0.006
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Krishnan B, Hedstrom L, Hebert DN, Gierasch LM, Gershenson A. Expression and Purification of Active Recombinant Human Alpha-1 Antitrypsin (AAT) from Escherichia coli. Methods Mol Biol. 2017; 1639:195-209.
Score: 0.005
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Chandrasekhar K, Ke H, Wang N, Goodwin T, Gierasch LM, Gershenson A, Hebert DN. Cellular folding pathway of a metastable serpin. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):6484-9.
Score: 0.005
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Gershenson A, Gierasch LM, Pastore A, Radford SE. Energy landscapes of functional proteins are inherently risky. Nat Chem Biol. 2014 Nov; 10(11):884-91.
Score: 0.004
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Theillet FX, Binolfi A, Frembgen-Kesner T, Hingorani K, Sarkar M, Kyne C, Li C, Crowley PB, Gierasch L, Pielak GJ, Elcock AH, Gershenson A, Selenko P. Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev. 2014 Jul 09; 114(13):6661-714.
Score: 0.004
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Gierasch LM. Molecular chaperones. Panning for chaperone-binding peptides. Curr Biol. 1994 Feb 01; 4(2):173-4.
Score: 0.004
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Liu Y, Gierasch LM, Bahar I. Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs. PLoS Comput Biol. 2010 Sep 16; 6(9).
Score: 0.003
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Ghosh RP, Nikitina T, Horowitz-Scherer RA, Gierasch LM, Uversky VN, Hite K, Hansen JC, Woodcock CL. Unique physical properties and interactions of the domains of methylated DNA binding protein 2. Biochemistry. 2010 May 25; 49(20):4395-410.
Score: 0.003
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Ghosh RP, Horowitz-Scherer RA, Nikitina T, Gierasch LM, Woodcock CL. Rett syndrome-causing mutations in human MeCP2 result in diverse structural changes that impact folding and DNA interactions. J Biol Chem. 2008 Jul 18; 283(29):20523-34.
Score: 0.003
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Ramamoorthy A, Gierasch LM, Opella SJ. Four-dimensional solid-state NMR experiment that correlates the chemical-shift and dipolar-coupling frequencies of two heteronuclei with the exchange of dilute-spin magnetization. J Magn Reson B. 1995 Oct; 109(1):112-6.
Score: 0.001
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Reiss Y, Stradley SJ, Gierasch LM, Brown MS, Goldstein JL. Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):732-6.
Score: 0.001