Lila Gierasch to Animals
This is a "connection" page, showing publications Lila Gierasch has written about Animals.
Connection Strength
0.741
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Gierasch LM. From Rat Tails to Glycoproteostasis: Motivated by Biology, Enabled by Biophysics, and Lucky. J Mol Biol. 2025 06 01; 437(11):169055.
Score: 0.068
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Bhasne K, Bogoian-Mullen A, Clerico EM, Gierasch LM. The Hsc70 system maintains the synaptic SNARE protein SNAP-25 in an assembly-competent state and delays its aggregation. J Biol Chem. 2024 12; 300(12):108001.
Score: 0.067
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Powers ET, Gierasch LM. The Proteome Folding Problem and Cellular Proteostasis. J Mol Biol. 2021 10 01; 433(20):167197.
Score: 0.053
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Mayer MP, Gierasch LM. Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones. J Biol Chem. 2019 02 08; 294(6):2085-2097.
Score: 0.044
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Meng W, Clerico EM, McArthur N, Gierasch LM. Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):11970-11975.
Score: 0.044
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Hebert DN, Clerico EM, Gierasch LM. Division of Labor: ER-Resident BiP Co-Chaperones Match Substrates to Fates Based on Specific Binding Sequences. Mol Cell. 2016 09 01; 63(5):721-3.
Score: 0.038
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Gierasch LM. What's in a Name? J Biol Chem. 2016 08 26; 291(35):19208-9.
Score: 0.038
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Clerico EM, Tilitsky JM, Meng W, Gierasch LM. How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions. J Mol Biol. 2015 Apr 10; 427(7):1575-88.
Score: 0.034
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Hingorani KS, Gierasch LM. Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge. Curr Opin Struct Biol. 2014 Feb; 24:81-90.
Score: 0.031
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Ferrolino MC, Zhuravleva A, Budyak IL, Krishnan B, Gierasch LM. Delicate balance between functionally required flexibility and aggregation risk in a ?-rich protein. Biochemistry. 2013 Dec 10; 52(49):8843-54.
Score: 0.031
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Budyak IL, Zhuravleva A, Gierasch LM. The Role of Aromatic-Aromatic Interactions in Strand-Strand Stabilization of ?-Sheets. J Mol Biol. 2013 Sep 23; 425(18):3522-35.
Score: 0.030
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Budyak IL, Krishnan B, Marcelino-Cruz AM, Ferrolino MC, Zhuravleva A, Gierasch LM. Early folding events protect aggregation-prone regions of a ?-rich protein. Structure. 2013 Mar 05; 21(3):476-85.
Score: 0.030
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Hebert DN, Gierasch LM. The molecular dating game: an antibody heavy chain hangs loose with a chaperone while waiting for its life partner. Mol Cell. 2009 Jun 26; 34(6):635-6.
Score: 0.023
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Gierasch LM. A tribute to the career of a gentle giant of peptide science. Biopolymers. 2008; 90(3):153.
Score: 0.021
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Ignatova Z, Thakur AK, Wetzel R, Gierasch LM. In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence. J Biol Chem. 2007 Dec 14; 282(50):36736-43.
Score: 0.020
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Ignatova Z, Krishnan B, Bombardier JP, Marcelino AM, Hong J, Gierasch LM. From the test tube to the cell: exploring the folding and aggregation of a beta-clam protein. Biopolymers. 2007; 88(2):157-63.
Score: 0.019
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Guay KP, Ke H, Gierasch LM, Gershenson A, Hebert DN. Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types. Methods Mol Biol. 2024; 2750:143-163.
Score: 0.016
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Ke H, Guay KP, Flotte TR, Gierasch LM, Gershenson A, Hebert DN. Secretion of functional a1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2206103119.
Score: 0.014
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Cleverley RM, Zheng N, Gierasch LM. The cost of exposing a hydrophobic loop and implications for the functional role of 4.5 S RNA in the Escherichia coli signal recognition particle. J Biol Chem. 2001 Jun 01; 276(22):19327-31.
Score: 0.013
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Adams BM, Ke H, Gierasch LM, Gershenson A, Hebert DN. Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control. J Biol Chem. 2019 12 13; 294(50):18992-19011.
Score: 0.012
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Zheng N, Gierasch LM. Signal sequences: the same yet different. Cell. 1996 Sep 20; 86(6):849-52.
Score: 0.009
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Chandrasekhar K, Ke H, Wang N, Goodwin T, Gierasch LM, Gershenson A, Hebert DN. Cellular folding pathway of a metastable serpin. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):6484-9.
Score: 0.009
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Theillet FX, Binolfi A, Frembgen-Kesner T, Hingorani K, Sarkar M, Kyne C, Li C, Crowley PB, Gierasch L, Pielak GJ, Elcock AH, Gershenson A, Selenko P. Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs). Chem Rev. 2014 Jul 09; 114(13):6661-714.
Score: 0.008
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Gierasch LM. Molecular chaperones. Panning for chaperone-binding peptides. Curr Biol. 1994 Feb 01; 4(2):173-4.
Score: 0.008
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Landry SJ, Gierasch LM. Polypeptide interactions with molecular chaperones and their relationship to in vivo protein folding. Annu Rev Biophys Biomol Struct. 1994; 23:645-69.
Score: 0.008
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Rizo J, Gierasch LM. Constrained peptides: models of bioactive peptides and protein substructures. Annu Rev Biochem. 1992; 61:387-418.
Score: 0.007
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Goldstein JL, Brown MS, Stradley SJ, Reiss Y, Gierasch LM. Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase. J Biol Chem. 1991 Aug 25; 266(24):15575-8.
Score: 0.007
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Liu Y, Gierasch LM, Bahar I. Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs. PLoS Comput Biol. 2010 Sep 16; 6(9).
Score: 0.006
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Lark LR, Berzofsky JA, Gierasch LM. T-cell antigenic peptides from sperm whale myoglobin fold as amphipathic helices: a possible determinant for immunodominance? Pept Res. 1989 Sep-Oct; 2(5):314-21.
Score: 0.006
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Hinz J, Gierasch LM, Ignatova Z. Orthogonal cross-seeding: an approach to explore protein aggregates in living cells. Biochemistry. 2008 Apr 08; 47(14):4196-200.
Score: 0.005
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Lin BR, Gierasch LM, Jiang C, Tai PC. Electrophysiological studies in Xenopus oocytes for the opening of Escherichia coli SecA-dependent protein-conducting channels. J Membr Biol. 2006; 214(2):103-13.
Score: 0.005
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Kabani M, Kelley SS, Morrow MW, Montgomery DL, Sivendran R, Rose MD, Gierasch LM, Brodsky JL. Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP. Mol Biol Cell. 2003 Aug; 14(8):3437-48.
Score: 0.004
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Kibbey RG, Rizo J, Gierasch LM, Anderson RG. The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation. J Cell Biol. 1998 Jul 13; 142(1):59-67.
Score: 0.003
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Bechinger B, Gierasch LM, Montal M, Zasloff M, Opella SJ. Orientations of helical peptides in membrane bilayers by solid state NMR spectroscopy. Solid State Nucl Magn Reson. 1996 Dec; 7(3):185-91.
Score: 0.002
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Rivier J, Jiang GC, Lahrichi SL, Porter J, Koerber SC, Rizo J, Corrigan A, Gierasch L, Hagler A, Vale W, Rivier C. Dose relationship between GnRH antagonists and pituitary suppression. Hum Reprod. 1996 Nov; 11 Suppl 3:133-47.
Score: 0.002
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Hoyt DW, Cyr DM, Gierasch LM, Douglas MG. Interaction of peptides corresponding to mitochondrial presequences with membranes. J Biol Chem. 1991 Nov 15; 266(32):21693-9.
Score: 0.002
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Reiss Y, Stradley SJ, Gierasch LM, Brown MS, Goldstein JL. Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):732-6.
Score: 0.002
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Struthers RS, Tanaka G, Koerber SC, Solmajer T, Baniak EL, Gierasch LM, Vale W, Rivier J, Hagler AT. Design of biologically active, conformationally constrained GnRH antagonists. Proteins. 1990; 8(4):295-304.
Score: 0.001