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Connection

Barbara Osborne to Humans

This is a "connection" page, showing publications Barbara Osborne has written about Humans.
Connection Strength

0.426
  1. Baker R, Lawlor R, Smith M, Price J, Eaton A, Lover A, Alfandari D, Reinhart P, Arcaro KF, Osborne BA. Antibody responses in blood and saliva post COVID-19 bivalent booster do not reveal an Omicron BA.4/BA.5- specific response. Front Immunol. 2024; 15:1401209.
    View in: PubMed
    Score: 0.035
  2. Mitra A, Shanthalingam S, Sherman HL, Singh K, Canakci M, Torres JA, Lawlor R, Ran Y, Golde TE, Miele L, Thayumanavan S, Minter LM, Osborne BA. CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells. Front Immunol. 2020; 11:735.
    View in: PubMed
    Score: 0.026
  3. Vijayaraghavan J, Osborne BA. Notch and T Cell Function - A Complex Tale. Adv Exp Med Biol. 2018; 1066:339-354.
    View in: PubMed
    Score: 0.023
  4. Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114.
    View in: PubMed
    Score: 0.015
  5. Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. J Immunol. 2011 Jul 15; 187(2):692-701.
    View in: PubMed
    Score: 0.014
  6. Wang A, Rud J, Olson CM, Anguita J, Osborne BA. Phosphorylation of Nur77 by the MEK-ERK-RSK cascade induces mitochondrial translocation and apoptosis in T cells. J Immunol. 2009 Sep 01; 183(5):3268-77.
    View in: PubMed
    Score: 0.013
  7. Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98.
    View in: PubMed
    Score: 0.012
  8. Osborne BA, Minter LM. Notch signalling during peripheral T-cell activation and differentiation. Nat Rev Immunol. 2007 Jan; 7(1):64-75.
    View in: PubMed
    Score: 0.010
  9. Miele L, Golde T, Osborne B. Notch signaling in cancer. Curr Mol Med. 2006 Dec; 6(8):905-18.
    View in: PubMed
    Score: 0.010
  10. Granowitz EV, Tonomura N, Benson RM, Katz DM, Band V, Makari-Judson GP, Osborne BA. Hyperbaric oxygen inhibits benign and malignant human mammary epithelial cell proliferation. Anticancer Res. 2005 Nov-Dec; 25(6B):3833-42.
    View in: PubMed
    Score: 0.010
  11. Osborne BA, Kee BL. Lymphoid development: it's not 'all Greek to us' any more. Nat Immunol. 2005 Feb; 6(2):119-23.
    View in: PubMed
    Score: 0.009
  12. Kalinina O, Minter LM, Sperling AI, Hollinger MK, Le P, Osborne BA, Zhang S, Stiff P, Knight KL. Exopolysaccharide-Treated Dendritic Cells Effectively Ameliorate Acute Graft-versus-Host Disease. Transplant Cell Ther. 2024 Jan; 30(1):79.e1-79.e10.
    View in: PubMed
    Score: 0.008
  13. Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, Del Valle L, Hicks C, Zabaleta J, Golde T, Osborne B, Miele L. Sulindac sulfide as a non-immune suppressive ?-secretase modulator to target triple-negative breast cancer. Front Immunol. 2023; 14:1244159.
    View in: PubMed
    Score: 0.008
  14. Minter LM, Osborne BA. Cell death in the thymus--it' s all a matter of contacts. Semin Immunol. 2003 Jun; 15(3):135-44.
    View in: PubMed
    Score: 0.008
  15. Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, Loh C, Miele L. Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Front Immunol. 2022; 13:987298.
    View in: PubMed
    Score: 0.008
  16. Liu B, Singh K, Gong S, Canakci M, Osborne BA, Thayumanavan S. Protein-Antibody Conjugates (PACs): A Plug-and-Play Strategy for Covalent Conjugation and Targeted Intracellular Delivery of Pristine Proteins. Angew Chem Int Ed Engl. 2021 06 01; 60(23):12813-12818.
    View in: PubMed
    Score: 0.007
  17. Majumder S, Crabtree JS, Golde TE, Minter LM, Osborne BA, Miele L. Targeting Notch in oncology: the path forward. Nat Rev Drug Discov. 2021 02; 20(2):125-144.
    View in: PubMed
    Score: 0.007
  18. Ozay EI, Shanthalingam S, Sherman HL, Torres JA, Osborne BA, Tew GN, Minter LM. Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells. Mol Ther. 2020 09 02; 28(9):1987-2006.
    View in: PubMed
    Score: 0.007
  19. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. ?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not. Alzheimers Res Ther. 2020 05 19; 12(1):61.
    View in: PubMed
    Score: 0.007
  20. Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis. J Cell Physiol. 1999 Dec; 181(3):393-409.
    View in: PubMed
    Score: 0.006
  21. Osborne B, Miele L. Notch and the immune system. Immunity. 1999 Dec; 11(6):653-63.
    View in: PubMed
    Score: 0.006
  22. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. J Biol Chem. 2019 07 19; 294(29):11276-11285.
    View in: PubMed
    Score: 0.006
  23. Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus? iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 03; 35:101401.
    View in: PubMed
    Score: 0.006
  24. Jehn BM, Bielke W, Pear WS, Osborne BA. Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. J Immunol. 1999 Jan 15; 162(2):635-8.
    View in: PubMed
    Score: 0.006
  25. Munkhbat O, Canakci M, Zheng S, Hu W, Osborne B, Bogdanov AA, Thayumanavan S. 19F MRI of Polymer Nanogels Aided by Improved Segmental Mobility of Embedded Fluorine Moieties. Biomacromolecules. 2019 02 11; 20(2):790-800.
    View in: PubMed
    Score: 0.006
  26. Bostwick DG, Iczkowski KA, Amin MB, Discigil G, Osborne B. Malignant lymphoma involving the prostate: report of 62 cases. Cancer. 1998 Aug 15; 83(4):732-8.
    View in: PubMed
    Score: 0.006
  27. Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Front Immunol. 2018; 9:1288.
    View in: PubMed
    Score: 0.006
  28. Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017 10 15; 77(20):5628-5638.
    View in: PubMed
    Score: 0.006
  29. Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. ?-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. EMBO Mol Med. 2017 07; 9(7):950-966.
    View in: PubMed
    Score: 0.005
  30. Karau MJ, Tilahun ME, Krogman A, Osborne BA, Goldsby RA, David CS, Mandrekar JN, Patel R, Rajagopalan G. Passive therapy with humanized anti-staphylococcal enterotoxin B antibodies attenuates systemic inflammatory response and protects from lethal pneumonia caused by staphylococcal enterotoxin B-producing Staphylococcus aureus. Virulence. 2017 10 03; 8(7):1148-1159.
    View in: PubMed
    Score: 0.005
  31. Ozay EI, Gonzalez-Perez G, Torres JA, Vijayaraghavan J, Lawlor R, Sherman HL, Garrigan DT, Burnside AS, Osborne BA, Tew GN, Minter LM. Intracellular Delivery of Anti-pPKC? (Thr538) via Protein Transduction Domain Mimics for Immunomodulation. Mol Ther. 2016 Dec; 24(12):2118-2130.
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    Score: 0.005
  32. Wang Y, Yu S, Huang D, Cui M, Hu H, Zhang L, Wang W, Parameswaran N, Jackson M, Osborne B, Bedogni B, Li C, Sy MS, Xin W, Zhou L. Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1. Am J Pathol. 2016 11; 186(11):2945-2956.
    View in: PubMed
    Score: 0.005
  33. Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, Gomez CR, Golde T, Osborne B, Miele L. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1. J Cell Physiol. 2015 Dec; 230(12):3115-27.
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    Score: 0.005
  34. Prasad P, Molla MR, Cui W, Canakci M, Osborne B, Mager J, Thayumanavan S. Polyamide Nanogels from Generally Recognized as Safe Components and Their Toxicity in Mouse Preimplantation Embryos. Biomacromolecules. 2015 Nov 09; 16(11):3491-8.
    View in: PubMed
    Score: 0.005
  35. Gordon MR, Canakci M, Li L, Zhuang J, Osborne B, Thayumanavan S. Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists. Bioconjug Chem. 2015 Nov 18; 26(11):2198-215.
    View in: PubMed
    Score: 0.005
  36. Osborne BA, Schwartz LM. Cell death suffers a TKO. Bioessays. 1995 Jun; 17(6):557-9.
    View in: PubMed
    Score: 0.005
  37. Osborne BA. Induction of genes during apoptosis: examples from the immune system. Semin Cancer Biol. 1995 Feb; 6(1):27-33.
    View in: PubMed
    Score: 0.005
  38. Osborne BA, Smith SW, Liu ZG, McLaughlin KA, Schwartz LM. Transient transfection assays to examine the requirement of putative cell death genes. Methods Cell Biol. 1995; 46:99-106.
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    Score: 0.005
  39. Smith SW, McLaughlin KA, Osborne BA. Molecular events in thymocyte apoptosis. Curr Top Microbiol Immunol. 1995; 200:147-62.
    View in: PubMed
    Score: 0.005
  40. Osborne BA, Smith SW, Liu ZG, McLaughlin KA, Grimm L, Schwartz LM. Identification of genes induced during apoptosis in T lymphocytes. Immunol Rev. 1994 Dec; 142:301-20.
    View in: PubMed
    Score: 0.005
  41. Schwartz LM, Osborne BA. Ced-3/ICE: evolutionarily conserved regulation of cell death. Bioessays. 1994 Jun; 16(6):387-9.
    View in: PubMed
    Score: 0.004
  42. Sgolastra F, Minter LM, Osborne BA, Tew GN. Importance of sequence specific hydrophobicity in synthetic protein transduction domain mimics. Biomacromolecules. 2014 Mar 10; 15(3):812-20.
    View in: PubMed
    Score: 0.004
  43. Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. ?-Secretase inhibitors and modulators. Biochim Biophys Acta. 2013 Dec; 1828(12):2898-907.
    View in: PubMed
    Score: 0.004
  44. Tezgel A?, Gonzalez-Perez G, Telfer JC, Osborne BA, Minter LM, Tew GN. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013 Jan; 21(1):201-9.
    View in: PubMed
    Score: 0.004
  45. Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of A? production prior to deposition results in sustained reduction of amyloid plaque pathology. Mol Neurodegener. 2012 Aug 14; 7:39.
    View in: PubMed
    Score: 0.004
  46. Sheth PM, Yi TJ, Kovacs C, Kemal KS, Jones RB, Osborne B, Pilon R, la Porte C, Ostrowski M, Mazzulli T, Burger H, Weiser B, Kaul R. Mucosal correlates of isolated HIV semen shedding during effective antiretroviral therapy. Mucosal Immunol. 2012 May; 5(3):248-57.
    View in: PubMed
    Score: 0.004
  47. Tilahun ME, Kwan A, Natarajan K, Quinn M, Tilahun AY, Xie C, Margulies DH, Osborne BA, Goldsby RA, Rajagopalan G. Chimeric anti-staphylococcal enterotoxin B antibodies and lovastatin act synergistically to provide in vivo protection against lethal doses of SEB. PLoS One. 2011; 6(11):e27203.
    View in: PubMed
    Score: 0.004
  48. Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Targeting Notch to target cancer stem cells. Clin Cancer Res. 2010 Jun 15; 16(12):3141-52.
    View in: PubMed
    Score: 0.003
  49. Tilahun ME, Rajagopalan G, Shah-Mahoney N, Lawlor RG, Tilahun AY, Xie C, Natarajan K, Margulies DH, Ratner DI, Osborne BA, Goldsby RA. Potent neutralization of staphylococcal enterotoxin B by synergistic action of chimeric antibodies. Infect Immun. 2010 Jun; 78(6):2801-11.
    View in: PubMed
    Score: 0.003
  50. Osborne B, Collins K, Klein F, Smith MJ, Koontz WW. Twenty-five years of renal trauma at a teaching hospital. Va Med. 1989 Dec; 116(12):504-7.
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    Score: 0.003
  51. Hao L, Rizzo P, Osipo C, Pannuti A, Wyatt D, Cheung LW, Sonenshein G, Osborne BA, Miele L. Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene. 2010 Jan 14; 29(2):201-13.
    View in: PubMed
    Score: 0.003
  52. Rizzo P, Osipo C, Pannuti A, Golde T, Osborne B, Miele L. Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Adv Enzyme Regul. 2009; 49(1):134-41.
    View in: PubMed
    Score: 0.003
  53. Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 2008 Sep 01; 27(38):5124-31.
    View in: PubMed
    Score: 0.003
  54. Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, Lendahl U, Sonenshein G, Osborne B, Qin JZ, Pannuti A, Nickoloff BJ, Miele L. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene. 2008 Oct 02; 27(44):5833-44.
    View in: PubMed
    Score: 0.003
  55. Osipo C, Golde TE, Osborne BA, Miele LA. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Lab Invest. 2008 Jan; 88(1):11-7.
    View in: PubMed
    Score: 0.003
  56. Izadi H, Motameni AT, Bates TC, Olivera ER, Villar-Suarez V, Joshi I, Garg R, Osborne BA, Davis RJ, Rinc?n M, Anguita J. c-Jun N-terminal kinase 1 is required for Toll-like receptor 1 gene expression in macrophages. Infect Immun. 2007 Oct; 75(10):5027-34.
    View in: PubMed
    Score: 0.003
  57. Osborne BA, Lunney JK, Pennington L, Sachs DH, Rudikoff S. Two-dimensional gel analysis of swine histocompatibility antigens. J Immunol. 1983 Dec; 131(6):2939-44.
    View in: PubMed
    Score: 0.002
  58. Benson RM, Minter LM, Osborne BA, Granowitz EV. Hyperbaric oxygen inhibits stimulus-induced proinflammatory cytokine synthesis by human blood-derived monocyte-macrophages. Clin Exp Immunol. 2003 Oct; 134(1):57-62.
    View in: PubMed
    Score: 0.002
  59. Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene. 2003 Sep 29; 22(42):6598-608.
    View in: PubMed
    Score: 0.002
  60. Ganguly BJ, Tonomura N, Benson RM, Osborne BA, Granowitz EV. Hyperbaric oxygen enhances apoptosis in hematopoietic cells. Apoptosis. 2002 Dec; 7(6):499-510.
    View in: PubMed
    Score: 0.002
  61. Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med. 2002 Sep; 8(9):979-86.
    View in: PubMed
    Score: 0.002
  62. Kuroiwa Y, Kasinathan P, Choi YJ, Naeem R, Tomizuka K, Sullivan EJ, Knott JG, Duteau A, Goldsby RA, Osborne BA, Ishida I, Robl JM. Cloned transchromosomic calves producing human immunoglobulin. Nat Biotechnol. 2002 Sep; 20(9):889-94.
    View in: PubMed
    Score: 0.002
  63. Valavanis C, Hu Y, Yang Y, Osborne BA, Chouaib S, Greene L, Ashwell JD, Schwartz LM. Model cell lines for the study of apoptosis in vitro. Methods Cell Biol. 2001; 66:417-36.
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    Score: 0.002
  64. Lockshin RA, Osborne B, Zakeri Z. Cell death in the third millennium. Cell Death Differ. 2000 Jan; 7(1):2-7.
    View in: PubMed
    Score: 0.002
  65. Slavin MA, Osborne B, Adams R, Levenstein MJ, Schoch HG, Feldman AR, Meyers JD, Bowden RA. Efficacy and safety of fluconazole prophylaxis for fungal infections after marrow transplantation--a prospective, randomized, double-blind study. J Infect Dis. 1995 Jun; 171(6):1545-52.
    View in: PubMed
    Score: 0.001
  66. Harrington RD, Hooton TM, Hackman RC, Storch GA, Osborne B, Gleaves CA, Benson A, Meyers JD. An outbreak of respiratory syncytial virus in a bone marrow transplant center. J Infect Dis. 1992 Jun; 165(6):987-93.
    View in: PubMed
    Score: 0.001
  67. Srigley J, Barlogie B, Butler JJ, Osborne B, Blick M, Johnston D, Kantarjian H, Reuben J, Batsakis J, Freireich EJ. Heterogeneity of non-Hodgkin's lymphoma probed by nucleic acid cytometry. Blood. 1985 May; 65(5):1090-6.
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    Score: 0.001
  68. Lunney JK, Osborne BA, Sharrow SO, Devaux C, Pierres M, Sachs DH. Sharing of Ia antigens between species. IV. Interspecies cross-reactivity of monoclonal antibodies directed against polymorphic mouse Ia determinants. J Immunol. 1983 Jun; 130(6):2786-93.
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    Score: 0.001
  69. Roth JA, Osborne BA, Ames RS. Immunoregulatory factors derived from human tumors. II. Partial purification and further immunobiochemical characterization of a human sarcoma-derived immunosuppressive factor expressing HLA-DR and immunoglobulin-related determinants. J Immunol. 1983 Jan; 130(1):303-8.
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    Score: 0.000
  70. Roth JA, Grimm EA, Osborne BA, Putnam JB, Davidson DD, Ames RS. Suppressive immunoregulatory factors produced by tumors. Lymphokine Res. 1983; 2(2):67-73.
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    Score: 0.000
  71. Engleman EG, Benike C, Osborne B, Goldsby R. Functional characteristics of human T-cell subpopulations distinguished by a monoclonal antibody. Proc Natl Acad Sci U S A. 1980 Mar; 77(3):1607-11.
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    Score: 0.000
  72. Suomalainen HA, Goldsby RA, Osborne BA, Schr?der J. Mouse/human T-cell hybrids rosetting with sheep erythrocytes. Scand J Immunol. 1980; 11(2):163-8.
    View in: PubMed
    Score: 0.000
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.