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Connection

Barbara Osborne to Amyloid Precursor Protein Secretases

This is a "connection" page, showing publications Barbara Osborne has written about Amyloid Precursor Protein Secretases.
  1. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. ?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not. Alzheimers Res Ther. 2020 05 19; 12(1):61.
    View in: PubMed
    Score: 0.169
  2. Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. ?-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. EMBO Mol Med. 2017 07; 9(7):950-966.
    View in: PubMed
    Score: 0.138
  3. Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. ?-Secretase inhibitors and modulators. Biochim Biophys Acta. 2013 Dec; 1828(12):2898-907.
    View in: PubMed
    Score: 0.104
  4. Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of A? production prior to deposition results in sustained reduction of amyloid plaque pathology. Mol Neurodegener. 2012 Aug 14; 7:39.
    View in: PubMed
    Score: 0.098
  5. Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114.
    View in: PubMed
    Score: 0.094
  6. Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol. 2009 Mar 15; 182(6):3380-9.
    View in: PubMed
    Score: 0.078
  7. Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 01; 112(5):1813-21.
    View in: PubMed
    Score: 0.074
  8. Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, Golde TE, Miller SD, Osborne BA. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol. 2005 Jul; 6(7):680-8.
    View in: PubMed
    Score: 0.060
  9. Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, Del Valle L, Hicks C, Zabaleta J, Golde T, Osborne B, Miele L. Sulindac sulfide as a non-immune suppressive ?-secretase modulator to target triple-negative breast cancer. Front Immunol. 2023; 14:1244159.
    View in: PubMed
    Score: 0.053
  10. Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol. 2003 Sep 15; 171(6):3019-24.
    View in: PubMed
    Score: 0.053
  11. Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. J Biol Chem. 2019 07 19; 294(29):11276-11285.
    View in: PubMed
    Score: 0.039
  12. Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis. J Immunol. 2015 Dec 01; 195(11):5337-46.
    View in: PubMed
    Score: 0.031
  13. Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 2008 Sep 01; 27(38):5124-31.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.