Barbara Osborne to Amyloid Precursor Protein Secretases
This is a "connection" page, showing publications Barbara Osborne has written about Amyloid Precursor Protein Secretases.
Connection Strength
1.009
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Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. ?-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse ?-secretase modulators do not. Alzheimers Res Ther. 2020 05 19; 12(1):61.
Score: 0.168
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Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. ?-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. EMBO Mol Med. 2017 07; 9(7):950-966.
Score: 0.138
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Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. ?-Secretase inhibitors and modulators. Biochim Biophys Acta. 2013 Dec; 1828(12):2898-907.
Score: 0.104
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Das P, Verbeeck C, Minter L, Chakrabarty P, Felsenstein K, Kukar T, Maharvi G, Fauq A, Osborne BA, Golde TE. Transient pharmacologic lowering of A? production prior to deposition results in sustained reduction of amyloid plaque pathology. Mol Neurodegener. 2012 Aug 14; 7:39.
Score: 0.098
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Minter LM, Osborne BA. Canonical and non-canonical Notch signaling in CD4? T cells. Curr Top Microbiol Immunol. 2012; 360:99-114.
Score: 0.094
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Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol. 2009 Mar 15; 182(6):3380-9.
Score: 0.078
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Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 01; 112(5):1813-21.
Score: 0.074
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Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, Golde TE, Miller SD, Osborne BA. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat Immunol. 2005 Jul; 6(7):680-8.
Score: 0.060
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Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, Del Valle L, Hicks C, Zabaleta J, Golde T, Osborne B, Miele L. Sulindac sulfide as a non-immune suppressive ?-secretase modulator to target triple-negative breast cancer. Front Immunol. 2023; 14:1244159.
Score: 0.053
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Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol. 2003 Sep 15; 171(6):3019-24.
Score: 0.053
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Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. J Biol Chem. 2019 07 19; 294(29):11276-11285.
Score: 0.039
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Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis. J Immunol. 2015 Dec 01; 195(11):5337-46.
Score: 0.031
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Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 2008 Sep 01; 27(38):5124-31.
Score: 0.019