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Igor Kaltashov to Spectrometry, Mass, Electrospray Ionization

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This is a "connection" page, showing publications Igor Kaltashov has written about Spectrometry, Mass, Electrospray Ionization.
Igor Kaltashov
Connection Strength
14.284
Spectrometry, Mass, Electrospray Ionization
  1. Ivanov DG, Yang Y, Pawlowski JW, Carrick IJ, Kaltashov IA. Rapid Evaluation of the Extent of Haptoglobin Glycosylation Using Orthogonal Intact-Mass MS Approaches and Multivariate Analysis. Anal Chem. 2022 03 29; 94(12):5140-5148.
    View in: PubMed
    Score: 0.735
  2. Yang Y, Ivanov DG, Kaltashov IA. The challenge of structural heterogeneity in the native mass spectrometry studies of the SARS-CoV-2 spike protein interactions with its host cell-surface receptor. Anal Bioanal Chem. 2021 Dec; 413(29):7205-7214.
    View in: PubMed
    Score: 0.706
  3. Bobst CE, Sperry J, Friese OV, Kaltashov IA. Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction. J Am Soc Mass Spectrom. 2021 Jul 07; 32(7):1631-1637.
    View in: PubMed
    Score: 0.695
  4. Yang Y, Niu C, Bobst CE, Kaltashov IA. Charge Manipulation Using Solution and Gas-Phase Chemistry to Facilitate Analysis of Highly Heterogeneous Protein Complexes in Native Mass Spectrometry. Anal Chem. 2021 02 23; 93(7):3337-3342.
    View in: PubMed
    Score: 0.682
  5. Wang G, Bondarenko PV, Kaltashov IA. Multi-step conformational transitions in heat-treated protein therapeutics can be monitored in real time with temperature-controlled electrospray ionization mass spectrometry. Analyst. 2018 Feb 07; 143(3):670-677.
    View in: PubMed
    Score: 0.550
  6. Minsky BB, Dubin PL, Kaltashov IA. Electrostatic Forces as Dominant Interactions Between Proteins and Polyanions: an ESI MS Study of Fibroblast Growth Factor Binding to Heparin Oligomers. J Am Soc Mass Spectrom. 2017 04; 28(4):758-767.
    View in: PubMed
    Score: 0.517
  7. Xu S, Kaltashov IA. Evaluation of Gallium as a Tracer of Exogenous Hemoglobin-Haptoglobin Complexes for Targeted Drug Delivery Applications. J Am Soc Mass Spectrom. 2016 12; 27(12):2025-2032.
    View in: PubMed
    Score: 0.502
  8. Fatunmbi O, Abzalimov RR, Savinov SN, Gershenson A, Kaltashov IA. Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass Spectrometry. Biochemistry. 2016 Mar 29; 55(12):1918-28.
    View in: PubMed
    Score: 0.485
  9. Zhao Y, Abzalimov RR, Kaltashov IA. Interactions of Intact Unfractionated Heparin with Its Client Proteins Can Be Probed Directly Using Native Electrospray Ionization Mass Spectrometry. Anal Chem. 2016 Feb 02; 88(3):1711-8.
    View in: PubMed
    Score: 0.480
  10. Muneeruddin K, Nazzaro M, Kaltashov IA. Characterization of intact protein conjugates and biopharmaceuticals using ion-exchange chromatography with online detection by native electrospray ionization mass spectrometry and top-down tandem mass spectrometry. Anal Chem. 2015 Oct 06; 87(19):10138-45.
    View in: PubMed
    Score: 0.470
  11. Wang S, Bobst CE, Kaltashov IA. A new liquid chromatography-mass spectrometry-based method to quantitate exogenous recombinant transferrin in cerebrospinal fluid: a potential approach for pharmacokinetic studies of transferrin-based therapeutics in the central nervous systems. Eur J Mass Spectrom (Chichester). 2015; 21(3):369-76.
    View in: PubMed
    Score: 0.447
  12. Muneeruddin K, Thomas JJ, Salinas PA, Kaltashov IA. Characterization of small protein aggregates and oligomers using size exclusion chromatography with online detection by native electrospray ionization mass spectrometry. Anal Chem. 2014 Nov 04; 86(21):10692-9.
    View in: PubMed
    Score: 0.441
  13. Wang G, Kaltashov IA. Approach to characterization of the higher order structure of disulfide-containing proteins using hydrogen/deuterium exchange and top-down mass spectrometry. Anal Chem. 2014 Aug 05; 86(15):7293-8.
    View in: PubMed
    Score: 0.432
  14. Kaltashov IA, Bobst CE, Abzalimov RR. Mass spectrometry-based methods to study protein architecture and dynamics. Protein Sci. 2013 May; 22(5):530-44.
    View in: PubMed
    Score: 0.395
  15. Abzalimov RR, Bobst CE, Salinas PA, Savickas P, Thomas JJ, Kaltashov IA. Studies of pH-dependent self-association of a recombinant form of arylsulfatase A with electrospray ionization mass spectrometry and size-exclusion chromatography. Anal Chem. 2013 Feb 05; 85(3):1591-6.
    View in: PubMed
    Score: 0.389
  16. Wang S, Kaltashov IA. A new strategy of using O18-labeled iodoacetic acid for mass spectrometry-based protein quantitation. J Am Soc Mass Spectrom. 2012 Jul; 23(7):1293-7.
    View in: PubMed
    Score: 0.371
  17. Sjoelund V, Kaltashov IA. Modification of the zonal elution method for detection of transient protein-protein interactions involving ligand exchange. Anal Chem. 2012 May 15; 84(10):4608-12.
    View in: PubMed
    Score: 0.371
  18. Wang G, Johnson AJ, Kaltashov IA. Evaluation of electrospray ionization mass spectrometry as a tool for characterization of small soluble protein aggregates. Anal Chem. 2012 Feb 07; 84(3):1718-24.
    View in: PubMed
    Score: 0.363
  19. Abzalimov RR, Frimpong AK, Kaltashov IA. Detection and characterization of large-scale protein conformational transitions in solution using charge-state distribution analysis in ESI-MS. Methods Mol Biol. 2012; 896:365-73.
    View in: PubMed
    Score: 0.363
  20. Abzalimov RR, Kaltashov IA. Electrospray ionization mass spectrometry of highly heterogeneous protein systems: protein ion charge state assignment via incomplete charge reduction. Anal Chem. 2010 Sep 15; 82(18):7523-6.
    View in: PubMed
    Score: 0.332
  21. Leverence R, Mason AB, Kaltashov IA. Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8123-8.
    View in: PubMed
    Score: 0.322
  22. Abzalimov RR, Kaltashov IA. Controlling hydrogen scrambling in multiply charged protein ions during collisional activation: implications for top-down hydrogen/deuterium exchange MS utilizing collisional activation in the gas phase. Anal Chem. 2010 Feb 01; 82(3):942-50.
    View in: PubMed
    Score: 0.318
  23. Abzalimov RR, Kaplan DA, Easterling ML, Kaltashov IA. Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling. J Am Soc Mass Spectrom. 2009 Aug; 20(8):1514-7.
    View in: PubMed
    Score: 0.301
  24. Bobst CE, Abzalimov RR, Houde D, Kloczewiak M, Mhatre R, Berkowitz SA, Kaltashov IA. Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches. Anal Chem. 2008 Oct 01; 80(19):7473-81.
    View in: PubMed
    Score: 0.288
  25. Kaltashov IA, Abzalimov RR. Do ionic charges in ESI MS provide useful information on macromolecular structure? J Am Soc Mass Spectrom. 2008 Sep; 19(9):1239-46.
    View in: PubMed
    Score: 0.285
  26. Abzalimov RR, Dubin PL, Kaltashov IA. Glycosaminoglycans as naturally occurring combinatorial libraries: developing a mass spectrometry-based strategy for characterization of anti-thrombin interaction with low molecular weight heparin and heparin oligomers. Anal Chem. 2007 Aug 15; 79(16):6055-63.
    View in: PubMed
    Score: 0.266
  27. Kaltashov IA, Zhang M, Eyles SJ, Abzalimov RR. Investigation of structure, dynamics and function of metalloproteins with electrospray ionization mass spectrometry. Anal Bioanal Chem. 2006 Oct; 386(3):472-81.
    View in: PubMed
    Score: 0.250
  28. Kaltashov IA, Mohimen A. Estimates of protein surface areas in solution by electrospray ionization mass spectrometry. Anal Chem. 2005 Aug 15; 77(16):5370-9.
    View in: PubMed
    Score: 0.233
  29. Mohimen A, Dobo A, Hoerner JK, Kaltashov IA. A chemometric approach to detection and characterization of multiple protein conformers in solution using electrospray ionization mass spectrometry. Anal Chem. 2003 Aug 15; 75(16):4139-47.
    View in: PubMed
    Score: 0.203
  30. Gumerov DR, Mason AB, Kaltashov IA. Interlobe communication in human serum transferrin: metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry. Biochemistry. 2003 May 13; 42(18):5421-8.
    View in: PubMed
    Score: 0.199
  31. Muneeruddin K, Kaltashov IA, Wang G. Characterizing Soluble Protein Aggregates Using Native Mass Spectrometry Coupled with Temperature-Controlled Electrospray Ionization and Size-Excl usion Chromatography. Methods Mol Biol. 2022; 2406:455-468.
    View in: PubMed
    Score: 0.181
  32. Dobo A, Kaltashov IA. Detection of multiple protein conformational ensembles in solution via deconvolution of charge-state distributions in ESI MS. Anal Chem. 2001 Oct 15; 73(20):4763-73.
    View in: PubMed
    Score: 0.179
  33. Gumerov DR, Kaltashov IA. Dynamics of iron release from transferrin N-lobe studied by electrospray ionization mass spectrometry. Anal Chem. 2001 Jun 01; 73(11):2565-70.
    View in: PubMed
    Score: 0.174
  34. Xu S, Kaltashov IA. Overcoming the Hydrolytic Lability of a Reaction Intermediate in Production of Protein/Drug Conjugates: Conjugation of an Acyclic Nucleoside Phosphonate to a Model Carrier Protein. Mol Pharm. 2017 08 07; 14(8):2843-2851.
    View in: PubMed
    Score: 0.133
  35. Pawlowski JW, Kellicker N, Bobst CE, Kaltashov IA. Assessing the iron delivery efficacy of transferrin in clinical samples by native electrospray ionization mass spectrometry. Analyst. 2016 Feb 07; 141(3):853-61.
    View in: PubMed
    Score: 0.119
  36. Zhao H, Wang S, Nguyen SN, Elci SG, Kaltashov IA. Evaluation of Nonferrous Metals as Potential In Vivo Tracers of Transferrin-Based Therapeutics. J Am Soc Mass Spectrom. 2016 Feb; 27(2):211-9.
    View in: PubMed
    Score: 0.117
  37. Nguyen SN, Bobst CE, Kaltashov IA. Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate. Mol Pharm. 2013 May 06; 10(5):1998-2007.
    View in: PubMed
    Score: 0.099
  38. Bobst CE, Wang S, Shen WC, Kaltashov IA. Mass spectrometry study of a transferrin-based protein drug reveals the key role of protein aggregation for successful oral delivery. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13544-8.
    View in: PubMed
    Score: 0.094
  39. Kaltashov IA, Bobst CE, Zhang M, Leverence R, Gumerov DR. Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry. Biochim Biophys Acta. 2012 Mar; 1820(3):417-26.
    View in: PubMed
    Score: 0.087
  40. Wang G, Abzalimov RR, Kaltashov IA. Direct monitoring of heat-stressed biopolymers with temperature-controlled electrospray ionization mass spectrometry. Anal Chem. 2011 Apr 15; 83(8):2870-6.
    View in: PubMed
    Score: 0.086
  41. Bobst CE, Thomas JJ, Salinas PA, Savickas P, Kaltashov IA. Impact of oxidation on protein therapeutics: conformational dynamics of intact and oxidized acid-?-glucocerebrosidase at near-physiological pH. Protein Sci. 2010 Dec; 19(12):2366-78.
    View in: PubMed
    Score: 0.084
  42. Frimpong AK, Abzalimov RR, Uversky VN, Kaltashov IA. Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein. Proteins. 2010 Feb 15; 78(3):714-22.
    View in: PubMed
    Score: 0.080
  43. Frimpong AK, Abzalimov RR, Eyles SJ, Kaltashov IA. Gas-phase interference-free analysis of protein ion charge-state distributions: detection of small-scale conformational transitions accompanying pepsin inactivation. Anal Chem. 2007 Jun 01; 79(11):4154-61.
    View in: PubMed
    Score: 0.066
  44. Griffith WP, Kaltashov IA. Protein conformational heterogeneity as a binding catalyst: ESI-MS study of hemoglobin H formation. Biochemistry. 2007 Feb 20; 46(7):2020-6.
    View in: PubMed
    Score: 0.064
  45. Abzalimov RR, Kaltashov IA. Extraction of local hydrogen exchange data from HDX CAD MS measurements by deconvolution of isotopic distributions of fragment ions. J Am Soc Mass Spectrom. 2006 Nov; 17(11):1543-1551.
    View in: PubMed
    Score: 0.063
  46. Xiao H, Kaltashov IA. Transient structural disorder as a facilitator of protein-ligand binding: native H/D exchange-mass spectrometry study of cellular retinoic acid binding protein I. J Am Soc Mass Spectrom. 2005 Jun; 16(6):869-79.
    View in: PubMed
    Score: 0.057
  47. Zhang M, Gumerov DR, Kaltashov IA, Mason AB. Indirect detection of protein-metal binding: interaction of serum transferrin with In3+ and Bi3+. J Am Soc Mass Spectrom. 2004 Nov; 15(11):1658-64.
    View in: PubMed
    Score: 0.055
  48. Griffith WP, Kaltashov IA. Highly asymmetric interactions between globin chains during hemoglobin assembly revealed by electrospray ionization mass spectrometry. Biochemistry. 2003 Aug 26; 42(33):10024-33.
    View in: PubMed
    Score: 0.051
  49. Xiao H, Kaltashov IA, Eyles SJ. Indirect assessment of small hydrophobic ligand binding to a model protein using a combination of ESI MS and HDX/ESI MS. J Am Soc Mass Spectrom. 2003 May; 14(5):506-15.
    View in: PubMed
    Score: 0.050
  50. Mason AB, Halbrooks PJ, James NG, Byrne SL, Grady JK, Chasteen ND, Bobst CE, Kaltashov IA, Smith VC, MacGillivray RT, Everse SJ. Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin. Biochemistry. 2009 Mar 10; 48(9):1945-53.
    View in: PubMed
    Score: 0.019
  51. Mason AB, Judson GL, Bravo MC, Edelstein A, Byrne SL, James NG, Roush ED, Fierke CA, Bobst CE, Kaltashov IA, Daughtery MA. Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis. Biochemistry. 2008 Sep 16; 47(37):9847-55.
    View in: PubMed
    Score: 0.018
  52. Byrne SL, Leverence R, Klein JS, Giannetti AM, Smith VC, MacGillivray RT, Kaltashov IA, Mason AB. Effect of glycosylation on the function of a soluble, recombinant form of the transferrin receptor. Biochemistry. 2006 May 30; 45(21):6663-73.
    View in: PubMed
    Score: 0.015
Connection Strength

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