Igor Kaltashov to Protein Conformation
This is a "connection" page, showing publications Igor Kaltashov has written about Protein Conformation.
Connection Strength
4.544
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Kaltashov IA, Pawlowski JW, Yang W, Muneeruddin K, Yao H, Bobst CE, Lipatnikov AN. LC/MS at the whole protein level: Studies of biomolecular structure and interactions using native LC/MS and cross-path reactive chromatography (XP-RC) MS. Methods. 2018 07 15; 144:14-26.
Score: 0.468
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Wang G, Bondarenko PV, Kaltashov IA. Multi-step conformational transitions in heat-treated protein therapeutics can be monitored in real time with temperature-controlled electrospray ionization mass spectrometry. Analyst. 2018 Feb 07; 143(3):670-677.
Score: 0.459
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Wang G, Abzalimov RR, Bobst CE, Kaltashov IA. Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20087-92.
Score: 0.345
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Abzalimov RR, Kaltashov IA. Controlling hydrogen scrambling in multiply charged protein ions during collisional activation: implications for top-down hydrogen/deuterium exchange MS utilizing collisional activation in the gas phase. Anal Chem. 2010 Feb 01; 82(3):942-50.
Score: 0.265
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Kaltashov IA, Bobst CE, Abzalimov RR, Berkowitz SA, Houde D. Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry. J Am Soc Mass Spectrom. 2010 Mar; 21(3):323-37.
Score: 0.260
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Bobst CE, Zhang M, Kaltashov IA. Existence of a noncanonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry. J Mol Biol. 2009 May 22; 388(5):954-67.
Score: 0.249
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Mohimen A, Dobo A, Hoerner JK, Kaltashov IA. A chemometric approach to detection and characterization of multiple protein conformers in solution using electrospray ionization mass spectrometry. Anal Chem. 2003 Aug 15; 75(16):4139-47.
Score: 0.169
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Gumerov DR, Mason AB, Kaltashov IA. Interlobe communication in human serum transferrin: metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry. Biochemistry. 2003 May 13; 42(18):5421-8.
Score: 0.166
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Kaltashov IA, Eyles SJ. Studies of biomolecular conformations and conformational dynamics by mass spectrometry. Mass Spectrom Rev. 2002 Jan-Feb; 21(1):37-71.
Score: 0.151
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Yang W, Tu Z, McClements DJ, Kaltashov IA. A systematic assessment of structural heterogeneity and IgG/IgE-binding of ovalbumin. Food Funct. 2021 Sep 07; 12(17):8130-8140.
Score: 0.147
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Bobst CE, Sperry J, Friese OV, Kaltashov IA. Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction. J Am Soc Mass Spectrom. 2021 Jul 07; 32(7):1631-1637.
Score: 0.145
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Kaltashov IA, Bobst CE, Pawlowski J, Wang G. Mass spectrometry-based methods in characterization of the higher order structure of protein therapeutics. J Pharm Biomed Anal. 2020 May 30; 184:113169.
Score: 0.133
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Muneeruddin K, Nazzaro M, Kaltashov IA. Characterization of intact protein conjugates and biopharmaceuticals using ion-exchange chromatography with online detection by native electrospray ionization mass spectrometry and top-down tandem mass spectrometry. Anal Chem. 2015 Oct 06; 87(19):10138-45.
Score: 0.098
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Wang S, Kaltashov IA. Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. J Am Soc Mass Spectrom. 2015 May; 26(5):800-7.
Score: 0.094
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Muneeruddin K, Thomas JJ, Salinas PA, Kaltashov IA. Characterization of small protein aggregates and oligomers using size exclusion chromatography with online detection by native electrospray ionization mass spectrometry. Anal Chem. 2014 Nov 04; 86(21):10692-9.
Score: 0.092
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Bobst CE, Kaltashov IA. Enhancing the quality of H/D exchange measurements with mass spectrometry detection in disulfide-rich proteins using electron capture dissociation. Anal Chem. 2014 Jun 03; 86(11):5225-31.
Score: 0.089
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Kaltashov IA, Bobst CE, Abzalimov RR. Mass spectrometry-based methods to study protein architecture and dynamics. Protein Sci. 2013 May; 22(5):530-44.
Score: 0.082
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Abzalimov RR, Frimpong AK, Kaltashov IA. Detection and characterization of large-scale protein conformational transitions in solution using charge-state distribution analysis in ESI-MS. Methods Mol Biol. 2012; 896:365-73.
Score: 0.076
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Bobst CE, Kaltashov IA. Advanced mass spectrometry-based methods for the analysis of conformational integrity of biopharmaceutical products. Curr Pharm Biotechnol. 2011 Oct; 12(10):1517-29.
Score: 0.074
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Kaltashov IA, Bobst CE, Abzalimov RR, Wang G, Baykal B, Wang S. Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics. Biotechnol Adv. 2012 Jan-Feb; 30(1):210-22.
Score: 0.072
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Wang G, Abzalimov RR, Kaltashov IA. Direct monitoring of heat-stressed biopolymers with temperature-controlled electrospray ionization mass spectrometry. Anal Chem. 2011 Apr 15; 83(8):2870-6.
Score: 0.072
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Bobst CE, Thomas JJ, Salinas PA, Savickas P, Kaltashov IA. Impact of oxidation on protein therapeutics: conformational dynamics of intact and oxidized acid-?-glucocerebrosidase at near-physiological pH. Protein Sci. 2010 Dec; 19(12):2366-78.
Score: 0.070
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Frimpong AK, Abzalimov RR, Uversky VN, Kaltashov IA. Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein. Proteins. 2010 Feb 15; 78(3):714-22.
Score: 0.066
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Kaltashov IA, Bobst CE, Abzalimov RR. H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach? Anal Chem. 2009 Oct 01; 81(19):7892-9.
Score: 0.065
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Abzalimov RR, Kaplan DA, Easterling ML, Kaltashov IA. Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling. J Am Soc Mass Spectrom. 2009 Aug; 20(8):1514-7.
Score: 0.063
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Mason AB, Halbrooks PJ, James NG, Byrne SL, Grady JK, Chasteen ND, Bobst CE, Kaltashov IA, Smith VC, MacGillivray RT, Everse SJ. Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin. Biochemistry. 2009 Mar 10; 48(9):1945-53.
Score: 0.062
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Bobst CE, Abzalimov RR, Houde D, Kloczewiak M, Mhatre R, Berkowitz SA, Kaltashov IA. Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches. Anal Chem. 2008 Oct 01; 80(19):7473-81.
Score: 0.060
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Kaltashov IA, Abzalimov RR. Do ionic charges in ESI MS provide useful information on macromolecular structure? J Am Soc Mass Spectrom. 2008 Sep; 19(9):1239-46.
Score: 0.059
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Frimpong AK, Abzalimov RR, Eyles SJ, Kaltashov IA. Gas-phase interference-free analysis of protein ion charge-state distributions: detection of small-scale conformational transitions accompanying pepsin inactivation. Anal Chem. 2007 Jun 01; 79(11):4154-61.
Score: 0.055
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Griffith WP, Kaltashov IA. Protein conformational heterogeneity as a binding catalyst: ESI-MS study of hemoglobin H formation. Biochemistry. 2007 Feb 20; 46(7):2020-6.
Score: 0.054
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Abzalimov RR, Kaltashov IA. Extraction of local hydrogen exchange data from HDX CAD MS measurements by deconvolution of isotopic distributions of fragment ions. J Am Soc Mass Spectrom. 2006 Nov; 17(11):1543-1551.
Score: 0.052
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Xiao H, Kaltashov IA. Transient structural disorder as a facilitator of protein-ligand binding: native H/D exchange-mass spectrometry study of cellular retinoic acid binding protein I. J Am Soc Mass Spectrom. 2005 Jun; 16(6):869-79.
Score: 0.047
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Xiao H, Hoerner JK, Eyles SJ, Dobo A, Voigtman E, Mel'cuk AI, Kaltashov IA. Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment. Protein Sci. 2005 Feb; 14(2):543-57.
Score: 0.047
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Griffith WP, Kaltashov IA. Highly asymmetric interactions between globin chains during hemoglobin assembly revealed by electrospray ionization mass spectrometry. Biochemistry. 2003 Aug 26; 42(33):10024-33.
Score: 0.042
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Dobo A, Kaltashov IA. Detection of multiple protein conformational ensembles in solution via deconvolution of charge-state distributions in ESI MS. Anal Chem. 2001 Oct 15; 73(20):4763-73.
Score: 0.037
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Eyles SJ, Dresch T, Gierasch LM, Kaltashov IA. Unfolding dynamics of a beta-sheet protein studied by mass spectrometry. J Mass Spectrom. 1999 Dec; 34(12):1289-95.
Score: 0.033
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Steere AN, Roberts SE, Byrne SL, Dennis Chasteen N, Bobst CE, Kaltashov IA, Smith VC, MacGillivray RT, Mason AB. Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin. Protein Expr Purif. 2010 Jul; 72(1):32-41.
Score: 0.016
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Xiao H, Kaltashov IA, Eyles SJ. Indirect assessment of small hydrophobic ligand binding to a model protein using a combination of ESI MS and HDX/ESI MS. J Am Soc Mass Spectrom. 2003 May; 14(5):506-15.
Score: 0.010