Jeanne Hardy to Models, Molecular
This is a "connection" page, showing publications Jeanne Hardy has written about Models, Molecular.
Connection Strength
1.573
-
Hardy JA, Wells JA. Dissecting an allosteric switch in caspase-7 using chemical and mutational probes. J Biol Chem. 2009 Sep 18; 284(38):26063-9.
Score: 0.241
-
Hardy JA, Wells JA. Searching for new allosteric sites in enzymes. Curr Opin Struct Biol. 2004 Dec; 14(6):706-15.
Score: 0.175
-
Hill ME, Kumar A, Wells JA, Hobman TC, Julien O, Hardy JA. The Unique Cofactor Region of Zika Virus NS2B-NS3 Protease Facilitates Cleavage of Key Host Proteins. ACS Chem Biol. 2018 09 21; 13(9):2398-2405.
Score: 0.113
-
Huber KL, Serrano BP, Hardy JA. Caspase-9 CARD?:?core domain interactions require a properly formed active site. Biochem J. 2018 03 29; 475(6):1177-1196.
Score: 0.110
-
Eron SJ, Raghupathi K, Hardy JA. Dual Site Phosphorylation of Caspase-7 by PAK2 Blocks Apoptotic Activity by Two Distinct Mechanisms. Structure. 2017 01 03; 25(1):27-39.
Score: 0.100
-
Hill ME, MacPherson DJ, Wu P, Julien O, Wells JA, Hardy JA. Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. ACS Chem Biol. 2016 06 17; 11(6):1603-12.
Score: 0.096
-
Dagbay K, Eron SJ, Serrano BP, Vel?zquez-Delgado EM, Zhao Y, Lin D, Vaidya S, Hardy JA. A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases. Methods Enzymol. 2014; 544:215-49.
Score: 0.082
-
Wu P, Nicholls SB, Hardy JA. A tunable, modular approach to fluorescent protease-activated reporters. Biophys J. 2013 Apr 02; 104(7):1605-14.
Score: 0.078
-
Nicholls SB, Hardy JA. Structural basis of fluorescence quenching in caspase activatable-GFP. Protein Sci. 2013 Mar; 22(3):247-57.
Score: 0.077
-
Huber KL, Hardy JA. Mechanism of zinc-mediated inhibition of caspase-9. Protein Sci. 2012 Jul; 21(7):1056-65.
Score: 0.073
-
Vel?zquez-Delgado EM, Hardy JA. Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure. 2012 Apr 04; 20(4):742-51.
Score: 0.073
-
Witkowski WA, Hardy JA. A designed redox-controlled caspase. Protein Sci. 2011 Aug; 20(8):1421-31.
Score: 0.069
-
Vaidya S, Vel?zquez-Delgado EM, Abbruzzese G, Hardy JA. Substrate-induced conformational changes occur in all cleaved forms of caspase-6. J Mol Biol. 2011 Feb 11; 406(1):75-91.
Score: 0.066
-
Huber KL, Olson KD, Hardy JA. Robust production of a peptide library using methodological synchronization. Protein Expr Purif. 2009 Oct; 67(2):139-47.
Score: 0.060
-
Hardy JA, Lam J, Nguyen JT, O'Brien T, Wells JA. Discovery of an allosteric site in the caspases. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12461-6.
Score: 0.043
-
Okerberg ES, Dagbay KB, Green JL, Soni I, Aban A, Nomanbhoy TK, Savinov SN, Hardy JA, Kozarich JW. Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6. Biochemistry. 2019 12 31; 58(52):5320-5328.
Score: 0.030
-
Tubeleviciute-Aydin A, Zhou L, Sharma G, Soni IV, Savinov SN, Hardy JA, LeBlanc AC. Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity. Sci Rep. 2018 03 13; 8(1):4428.
Score: 0.027
-
Kim CS, Mout R, Zhao Y, Yeh YC, Tang R, Jeong Y, Duncan B, Hardy JA, Rotello VM. Co-delivery of protein and small molecule therapeutics using nanoparticle-stabilized nanocapsules. Bioconjug Chem. 2015 May 20; 26(5):950-4.
Score: 0.023
-
Jabaiah AM, Getz JA, Witkowski WA, Hardy JA, Daugherty PS. Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics. Biol Chem. 2012 Sep; 393(9):933-41.
Score: 0.019
-
L?pez GE, Col?n-D?az I, Cruz A, Ghosh S, Nicholls SB, Viswanathan U, Hardy JA, Auerbach SM. Modeling nonaqueous proton wires built from helical peptides: biased proton transfer driven by helical dipoles. J Phys Chem A. 2012 Feb 02; 116(4):1283-8.
Score: 0.018