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Phillip Zamore to Animals

This is a "connection" page, showing publications Phillip Zamore has written about Animals.
Connection Strength

2.799
  1. Gainetdinov I, Vega-Badillo J, Cecchini K, Bagci A, Colpan C, De D, Bailey S, Arif A, Wu PH, MacRae IJ, Zamore PD. Relaxed targeting rules help PIWI proteins silence transposons. Nature. 2023 Jul; 619(7969):394-402.
    View in: PubMed
    Score: 0.061
  2. Arif A, Bailey S, Izumi N, Anzelon TA, Ozata DM, Andersson C, Gainetdinov I, MacRae IJ, Tomari Y, Zamore PD. GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins. Nature. 2022 08; 608(7923):618-625.
    View in: PubMed
    Score: 0.057
  3. Jouravleva K, Vega-Badillo J, Zamore PD. Principles and pitfalls of high-throughput analysis of microRNA-binding thermodynamics and kinetics by RNA Bind-n-Seq. Cell Rep Methods. 2022 03 28; 2(3):100185.
    View in: PubMed
    Score: 0.056
  4. Gainetdinov I, Colpan C, Cecchini K, Arif A, Jouravleva K, Albosta P, Vega-Badillo J, Lee Y, ?zata DM, Zamore PD. Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability. Mol Cell. 2021 12 02; 81(23):4826-4842.e8.
    View in: PubMed
    Score: 0.055
  5. Wu PH, Zamore PD. Defining the functions of PIWI-interacting RNAs. Nat Rev Mol Cell Biol. 2021 04; 22(4):239-240.
    View in: PubMed
    Score: 0.053
  6. Wu PH, Fu Y, Cecchini K, ?zata DM, Arif A, Yu T, Colpan C, Gainetdinov I, Weng Z, Zamore PD. The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility. Nat Genet. 2020 07; 52(7):728-739.
    View in: PubMed
    Score: 0.050
  7. ?zata DM, Yu T, Mou H, Gainetdinov I, Colpan C, Cecchini K, Kaymaz Y, Wu PH, Fan K, Kucukural A, Weng Z, Zamore PD. Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans. Nat Ecol Evol. 2020 01; 4(1):156-168.
    View in: PubMed
    Score: 0.048
  8. Ge DT, Wang W, Tipping C, Gainetdinov I, Weng Z, Zamore PD. The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria. Mol Cell. 2019 06 06; 74(5):982-995.e6.
    View in: PubMed
    Score: 0.046
  9. Li C, Zamore PD. RNAi in Mammalian Cells by siRNA Duplex Transfection. Cold Spring Harb Protoc. 2019 04 01; 2019(4).
    View in: PubMed
    Score: 0.046
  10. Li C, Zamore PD. RNAi in Drosophila S2 Cells by siRNA Duplex or dsRNA Transfection. Cold Spring Harb Protoc. 2019 04 01; 2019(4).
    View in: PubMed
    Score: 0.046
  11. Li C, Zamore PD. RNA Interference and Small RNA Analysis. Cold Spring Harb Protoc. 2019 04 01; 2019(4).
    View in: PubMed
    Score: 0.046
  12. Li C, Zamore PD. RNAi in Drosophila S2 Cells by dsRNA Soaking. Cold Spring Harb Protoc. 2019 03 01; 2019(3).
    View in: PubMed
    Score: 0.046
  13. Ozata DM, Gainetdinov I, Zoch A, O'Carroll D, Zamore PD. PIWI-interacting RNAs: small RNAs with big functions. Nat Rev Genet. 2019 02; 20(2):89-108.
    View in: PubMed
    Score: 0.045
  14. Chang TH, Mattei E, Gainetdinov I, Colpan C, Weng Z, Zamore PD. Maelstrom Represses Canonical Polymerase II Transcription within Bi-directional piRNA Clusters in Drosophila melanogaster. Mol Cell. 2019 01 17; 73(2):291-303.e6.
    View in: PubMed
    Score: 0.045
  15. Gainetdinov I, Colpan C, Arif A, Cecchini K, Zamore PD. A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals. Mol Cell. 2018 09 06; 71(5):775-790.e5.
    View in: PubMed
    Score: 0.044
  16. Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Cultured Mammalian Cells. Cold Spring Harb Protoc. 2018 02 01; 2018(2).
    View in: PubMed
    Score: 0.042
  17. Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Drosophila S2 Cells. Cold Spring Harb Protoc. 2018 02 01; 2018(2).
    View in: PubMed
    Score: 0.042
  18. Fu Y, Yang Y, Zhang H, Farley G, Wang J, Quarles KA, Weng Z, Zamore PD. The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology. Elife. 2018 01 29; 7.
    View in: PubMed
    Score: 0.042
  19. Ge DT, Tipping C, Brodsky MH, Zamore PD. Rapid Screening for CRISPR-Directed Editing of the Drosophila Genome Using white Coconversion. G3 (Bethesda). 2016 Oct 13; 6(10):3197-3206.
    View in: PubMed
    Score: 0.039
  20. Wang W, Han BW, Tipping C, Ge DT, Zhang Z, Weng Z, Zamore PD. Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms. Mol Cell. 2015 Sep 03; 59(5):819-30.
    View in: PubMed
    Score: 0.036
  21. Han BW, Wang W, Li C, Weng Z, Zamore PD. Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production. Science. 2015 May 15; 348(6236):817-21.
    View in: PubMed
    Score: 0.035
  22. Wang W, Yoshikawa M, Han BW, Izumi N, Tomari Y, Weng Z, Zamore PD. The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs. Mol Cell. 2014 Dec 04; 56(5):708-16.
    View in: PubMed
    Score: 0.034
  23. Zamore P. Startups on the menu: Alnylam. Nat Biotechnol. 2014 Sep; 32(9):866.
    View in: PubMed
    Score: 0.033
  24. Han BW, Zamore PD. piRNAs. Curr Biol. 2014 Aug 18; 24(16):R730-3.
    View in: PubMed
    Score: 0.033
  25. Broderick JA, Zamore PD. Competitive endogenous RNAs cannot alter microRNA function in vivo. Mol Cell. 2014 Jun 05; 54(5):711-3.
    View in: PubMed
    Score: 0.033
  26. Fukunaga R, Zamore PD. A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis. Cell Cycle. 2014; 13(11):1671-6.
    View in: PubMed
    Score: 0.033
  27. Zhang Z, Koppetsch BS, Wang J, Tipping C, Weng Z, Theurkauf WE, Zamore PD. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin. EMBO J. 2014 Mar 18; 33(6):536-9.
    View in: PubMed
    Score: 0.032
  28. Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. EMBO J. 2014 Feb 18; 33(4):371-84.
    View in: PubMed
    Score: 0.032
  29. Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol. 2013 Aug; 14(8):475-88.
    View in: PubMed
    Score: 0.031
  30. Li XZ, Roy CK, Moore MJ, Zamore PD. Defining piRNA primary transcripts. Cell Cycle. 2013 Jun 01; 12(11):1657-8.
    View in: PubMed
    Score: 0.030
  31. Ge DT, Zamore PD. Small RNA-directed silencing: the fly finds its inner fission yeast? Curr Biol. 2013 Apr 22; 23(8):R318-20.
    View in: PubMed
    Score: 0.030
  32. Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW, Xu J, Moore MJ, Schimenti JC, Weng Z, Zamore PD. An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell. 2013 Apr 11; 50(1):67-81.
    View in: PubMed
    Score: 0.030
  33. Flores-Jasso CF, Salomon WE, Zamore PD. Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates. RNA. 2013 Feb; 19(2):271-9.
    View in: PubMed
    Score: 0.030
  34. Wee LM, Flores-Jasso CF, Salomon WE, Zamore PD. Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties. Cell. 2012 Nov 21; 151(5):1055-67.
    View in: PubMed
    Score: 0.029
  35. Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell. 2012 Oct 26; 151(3):533-46.
    View in: PubMed
    Score: 0.029
  36. Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD. Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Mol Cell. 2011 Nov 18; 44(4):572-84.
    View in: PubMed
    Score: 0.027
  37. Broderick JA, Salomon WE, Ryder SP, Aronin N, Zamore PD. Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. RNA. 2011 Oct; 17(10):1858-69.
    View in: PubMed
    Score: 0.027
  38. Cenik ES, Zamore PD. Argonaute proteins. Curr Biol. 2011 Jun 21; 21(12):R446-9.
    View in: PubMed
    Score: 0.027
  39. Zamore PD, Ma S. Isolation of Drosophila melanogaster testes. J Vis Exp. 2011 May 13; (51).
    View in: PubMed
    Score: 0.027
  40. Cenik ES, Fukunaga R, Lu G, Dutcher R, Wang Y, Tanaka Hall TM, Zamore PD. Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease. Mol Cell. 2011 Apr 22; 42(2):172-84.
    View in: PubMed
    Score: 0.026
  41. Ameres SL, Hung JH, Xu J, Weng Z, Zamore PD. Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins. RNA. 2011 Jan; 17(1):54-63.
    View in: PubMed
    Score: 0.026
  42. Zamore PD. Somatic piRNA biogenesis. EMBO J. 2010 Oct 06; 29(19):3219-21.
    View in: PubMed
    Score: 0.025
  43. Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD. Target RNA-directed trimming and tailing of small silencing RNAs. Science. 2010 Jun 18; 328(5985):1534-9.
    View in: PubMed
    Score: 0.025
  44. Ghildiyal M, Xu J, Seitz H, Weng Z, Zamore PD. Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA. 2010 Jan; 16(1):43-56.
    View in: PubMed
    Score: 0.024
  45. Pfister EL, Zamore PD. Huntington's disease: silencing a brutal killer. Exp Neurol. 2009 Dec; 220(2):226-9.
    View in: PubMed
    Score: 0.024
  46. Izaurralde E, Zamore PD. Nucleus and gene expression. Curr Opin Cell Biol. 2009 Jun; 21(3):331-4.
    View in: PubMed
    Score: 0.023
  47. Barringhaus KG, Zamore PD. MicroRNAs: regulating a change of heart. Circulation. 2009 Apr 28; 119(16):2217-24.
    View in: PubMed
    Score: 0.023
  48. Li C, Vagin VV, Lee S, Xu J, Ma S, Xi H, Seitz H, Horwich MD, Syrzycka M, Honda BM, Kittler EL, Zapp ML, Klattenhoff C, Schulz N, Theurkauf WE, Weng Z, Zamore PD. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell. 2009 May 01; 137(3):509-21.
    View in: PubMed
    Score: 0.023
  49. Ghildiyal M, Seitz H, Horwich MD, Li C, Du T, Lee S, Xu J, Kittler EL, Zapp ML, Weng Z, Zamore PD. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science. 2008 May 23; 320(5879):1077-81.
    View in: PubMed
    Score: 0.021
  50. Seitz H, Ghildiyal M, Zamore PD. Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies. Curr Biol. 2008 Jan 22; 18(2):147-51.
    View in: PubMed
    Score: 0.021
  51. Horwich MD, Zamore PD. Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nat Protoc. 2008; 3(10):1537-49.
    View in: PubMed
    Score: 0.021
  52. Matranga C, Zamore PD. Small silencing RNAs. Curr Biol. 2007 Sep 18; 17(18):R789-93.
    View in: PubMed
    Score: 0.021
  53. Du T, Zamore PD. Beginning to understand microRNA function. Cell Res. 2007 Aug; 17(8):661-3.
    View in: PubMed
    Score: 0.020
  54. F?rstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD. Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. Cell. 2007 Jul 27; 130(2):287-97.
    View in: PubMed
    Score: 0.020
  55. Tomari Y, Du T, Zamore PD. Sorting of Drosophila small silencing RNAs. Cell. 2007 Jul 27; 130(2):299-308.
    View in: PubMed
    Score: 0.020
  56. Horwich MD, Li C, Matranga C, Vagin V, Farley G, Wang P, Zamore PD. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol. 2007 Jul 17; 17(14):1265-72.
    View in: PubMed
    Score: 0.020
  57. Zamore PD. RNA silencing: genomic defence with a slice of pi. Nature. 2007 Apr 19; 446(7138):864-5.
    View in: PubMed
    Score: 0.020
  58. Zamore PD. RNA interference: big applause for silencing in Stockholm. Cell. 2006 Dec 15; 127(6):1083-6.
    View in: PubMed
    Score: 0.020
  59. Schwarz DS, Ding H, Kennington L, Moore JT, Schelter J, Burchard J, Linsley PS, Aronin N, Xu Z, Zamore PD. Designing siRNA that distinguish between genes that differ by a single nucleotide. PLoS Genet. 2006 Sep 08; 2(9):e140.
    View in: PubMed
    Score: 0.019
  60. Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, Zamore PD. A distinct small RNA pathway silences selfish genetic elements in the germline. Science. 2006 Jul 21; 313(5785):320-4.
    View in: PubMed
    Score: 0.019
  61. Seitz H, Zamore PD. Rethinking the microprocessor. Cell. 2006 Jun 02; 125(5):827-9.
    View in: PubMed
    Score: 0.019
  62. Sigova A, Vagin V, Zamore PD. Measuring the rates of transcriptional elongation in the female Drosophila melanogaster germ line by nuclear run-on. Cold Spring Harb Symp Quant Biol. 2006; 71:335-41.
    View in: PubMed
    Score: 0.018
  63. Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell. 2005 Nov 18; 123(4):607-20.
    View in: PubMed
    Score: 0.018
  64. Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development. 2005 Nov; 132(21):4645-52.
    View in: PubMed
    Score: 0.018
  65. Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science. 2005 Sep 02; 309(5740):1519-24.
    View in: PubMed
    Score: 0.018
  66. F?rstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 2005 Jul; 3(7):e236.
    View in: PubMed
    Score: 0.018
  67. Tomari Y, Zamore PD. Perspective: machines for RNAi. Genes Dev. 2005 Mar 01; 19(5):517-29.
    View in: PubMed
    Score: 0.017
  68. Tomari Y, Zamore PD. MicroRNA biogenesis: drosha can't cut it without a partner. Curr Biol. 2005 Jan 26; 15(2):R61-4.
    View in: PubMed
    Score: 0.017
  69. Tomari Y, Matranga C, Haley B, Martinez N, Zamore PD. A protein sensor for siRNA asymmetry. Science. 2004 Nov 19; 306(5700):1377-80.
    View in: PubMed
    Score: 0.017
  70. Haley B, Zamore PD. Kinetic analysis of the RNAi enzyme complex. Nat Struct Mol Biol. 2004 Jul; 11(7):599-606.
    View in: PubMed
    Score: 0.016
  71. Schwarz DS, Tomari Y, Zamore PD. The RNA-induced silencing complex is a Mg2+-dependent endonuclease. Curr Biol. 2004 May 04; 14(9):787-91.
    View in: PubMed
    Score: 0.016
  72. Tomari Y, Du T, Haley B, Schwarz DS, Bennett R, Cook HA, Koppetsch BS, Theurkauf WE, Zamore PD. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell. 2004 Mar 19; 116(6):831-41.
    View in: PubMed
    Score: 0.016
  73. Hutv?gner G, Simard MJ, Mello CC, Zamore PD. Sequence-specific inhibition of small RNA function. PLoS Biol. 2004 Apr; 2(4):E98.
    View in: PubMed
    Score: 0.016
  74. Tang G, Zamore PD. Biochemical dissection of RNA silencing in plants. Methods Mol Biol. 2004; 257:223-44.
    View in: PubMed
    Score: 0.016
  75. Matranga C, Zamore PD. Plant RNA interference in vitro. Cold Spring Harb Symp Quant Biol. 2004; 69:403-8.
    View in: PubMed
    Score: 0.016
  76. Schwarz DS, Hutv?gner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell. 2003 Oct 17; 115(2):199-208.
    View in: PubMed
    Score: 0.016
  77. Venkei ZG, Gainetdinov I, Bagci A, Starostik MR, Choi CP, Fingerhut JM, Chen P, Balsara C, Whitfield TW, Bell GW, Feng S, Jacobsen SE, Aravin AA, Kim JK, Zamore PD, Yamashita YM. A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila. Nat Cell Biol. 2023 Oct; 25(10):1495-1505.
    View in: PubMed
    Score: 0.016
  78. Haley B, Tang G, Zamore PD. In vitro analysis of RNA interference in Drosophila melanogaster. Methods. 2003 Aug; 30(4):330-6.
    View in: PubMed
    Score: 0.015
  79. Zamore PD, Aronin N. siRNAs knock down hepatitis. Nat Med. 2003 Mar; 9(3):266-7.
    View in: PubMed
    Score: 0.015
  80. Cecchini K, Biasini A, Yu T, S?flund M, Mou H, Arif A, Eghbali A, Colpan C, Gainetdinov I, de Rooij DG, Weng Z, Zamore PD, ?zata DM. The transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in mice. Reproduction. 2023 02 01; 165(2):183-196.
    View in: PubMed
    Score: 0.015
  81. Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA. Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol Cell. 2022 11 03; 82(21):4049-4063.e6.
    View in: PubMed
    Score: 0.015
  82. Schwarz DS, Hutv?gner G, Haley B, Zamore PD. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell. 2002 Sep; 10(3):537-48.
    View in: PubMed
    Score: 0.015
  83. Hutv?gner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 2002 Sep 20; 297(5589):2056-60.
    View in: PubMed
    Score: 0.014
  84. Zamore PD. Ancient pathways programmed by small RNAs. Science. 2002 May 17; 296(5571):1265-9.
    View in: PubMed
    Score: 0.014
  85. Schwarz DS, Zamore PD. Why do miRNAs live in the miRNP? Genes Dev. 2002 May 01; 16(9):1025-31.
    View in: PubMed
    Score: 0.014
  86. Hutv?gner G, Zamore PD. RNAi: nature abhors a double-strand. Curr Opin Genet Dev. 2002 Apr; 12(2):225-32.
    View in: PubMed
    Score: 0.014
  87. Nyk?nen A, Haley B, Zamore PD. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell. 2001 Nov 02; 107(3):309-21.
    View in: PubMed
    Score: 0.014
  88. Zamore PD. RNA interference: listening to the sound of silence. Nat Struct Biol. 2001 Sep; 8(9):746-50.
    View in: PubMed
    Score: 0.014
  89. Hutv?gner G, McLachlan J, Pasquinelli AE, B?lint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science. 2001 Aug 03; 293(5531):834-8.
    View in: PubMed
    Score: 0.013
  90. Yu T, Fan K, ?zata DM, Zhang G, Fu Y, Theurkauf WE, Zamore PD, Weng Z. Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes. Nat Commun. 2021 01 04; 12(1):73.
    View in: PubMed
    Score: 0.013
  91. Sharp PA, Zamore PD. Molecular biology. RNA interference. Science. 2000 Mar 31; 287(5462):2431-3.
    View in: PubMed
    Score: 0.012
  92. Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 2000 Mar 31; 101(1):25-33.
    View in: PubMed
    Score: 0.012
  93. Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C, Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, Gao G. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Mol Ther. 2020 02 05; 28(2):422-430.
    View in: PubMed
    Score: 0.012
  94. Becker WR, Ober-Reynolds B, Jouravleva K, Jolly SM, Zamore PD, Greenleaf WJ. High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2. Mol Cell. 2019 08 22; 75(4):741-755.e11.
    View in: PubMed
    Score: 0.012
  95. Zamore PD, Bartel DP, Lehmann R, Williamson JR. The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry. 1999 Jan 12; 38(2):596-604.
    View in: PubMed
    Score: 0.011
  96. Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G. Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nat Biotechnol. 2018 10; 36(9):839-842.
    View in: PubMed
    Score: 0.011
  97. Fu Y, Wu PH, Beane T, Zamore PD, Weng Z. Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers. BMC Genomics. 2018 Jul 13; 19(1):531.
    View in: PubMed
    Score: 0.011
  98. Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A. Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo. Nucleic Acids Res. 2018 03 16; 46(5):2185-2196.
    View in: PubMed
    Score: 0.011
  99. Lewis SH, Quarles KA, Yang Y, Tanguy M, Fr?zal L, Smith SA, Sharma PP, Cordaux R, Gilbert C, Giraud I, Collins DH, Zamore PD, Miska EA, Sarkies P, Jiggins FM. Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements. Nat Ecol Evol. 2018 Jan; 2(1):174-181.
    View in: PubMed
    Score: 0.010
  100. Zamore PD, Williamson JR, Lehmann R. The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins. RNA. 1997 Dec; 3(12):1421-33.
    View in: PubMed
    Score: 0.010
  101. Zamore PD, Lehmann R. Drosophila development: homeodomains and translational control. Curr Biol. 1996 Jul 01; 6(7):773-5.
    View in: PubMed
    Score: 0.009
  102. Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism. Nat Immunol. 2016 06; 17(6):677-86.
    View in: PubMed
    Score: 0.009
  103. Ouimet M, Ediriweera HN, Gundra UM, Sheedy FJ, Ramkhelawon B, Hutchison SB, Rinehold K, van Solingen C, Fullerton MD, Cecchini K, Rayner KJ, Steinberg GR, Zamore PD, Fisher EA, Loke P, Moore KJ. MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis. J Clin Invest. 2015 Oct 26; 125(12):4334-48.
    View in: PubMed
    Score: 0.009
  104. Salomon WE, Jolly SM, Moore MJ, Zamore PD, Serebrov V. Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides. Cell. 2015 Jul 02; 162(1):84-95.
    View in: PubMed
    Score: 0.009
  105. Chou MT, Han BW, Hsiao CP, Zamore PD, Weng Z, Hung JH. Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs. Nucleic Acids Res. 2015 Sep 30; 43(17):e109.
    View in: PubMed
    Score: 0.009
  106. Curtis D, Lehmann R, Zamore PD. Translational regulation in development. Cell. 1995 Apr 21; 81(2):171-8.
    View in: PubMed
    Score: 0.009
  107. Roy CK, Olson S, Graveley BR, Zamore PD, Moore MJ. Assessing long-distance RNA sequence connectivity via RNA-templated DNA-DNA ligation. Elife. 2015 Apr 13; 4.
    View in: PubMed
    Score: 0.009
  108. Marinov GK, Wang J, Handler D, Wold BJ, Weng Z, Hannon GJ, Aravin AA, Zamore PD, Brennecke J, Toth KF. Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified. Dev Cell. 2015 Mar 23; 32(6):765-71.
    View in: PubMed
    Score: 0.009
  109. Han BW, Wang W, Zamore PD, Weng Z. piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing. Bioinformatics. 2015 Feb 15; 31(4):593-5.
    View in: PubMed
    Score: 0.008
  110. Zhang Z, Wang J, Schultz N, Zhang F, Parhad SS, Tu S, Vreven T, Zamore PD, Weng Z, Theurkauf WE. The HP1 homolog rhino anchors a nuclear complex that suppresses piRNA precursor splicing. Cell. 2014 Jun 05; 157(6):1353-1363.
    View in: PubMed
    Score: 0.008
  111. Moran Y, Fredman D, Praher D, Li XZ, Wee LM, Rentzsch F, Zamore PD, Technau U, Seitz H. Cnidarian microRNAs frequently regulate targets by cleavage. Genome Res. 2014 Apr; 24(4):651-63.
    View in: PubMed
    Score: 0.008
  112. Zhang F, Wang J, Xu J, Zhang Z, Koppetsch BS, Schultz N, Vreven T, Meignin C, Davis I, Zamore PD, Weng Z, Theurkauf WE. UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell. 2012 Nov 09; 151(4):871-884.
    View in: PubMed
    Score: 0.007
  113. Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. Nat Methods. 2012 Mar 04; 9(4):403-9.
    View in: PubMed
    Score: 0.007
  114. Zamore PD, Patton JG, Green MR. Cloning and domain structure of the mammalian splicing factor U2AF. Nature. 1992 Feb 13; 355(6361):609-14.
    View in: PubMed
    Score: 0.007
  115. Mueller C, Tang Q, Gruntman A, Blomenkamp K, Teckman J, Song L, Zamore PD, Flotte TR. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles. Mol Ther. 2012 03; 20(3):590-600.
    View in: PubMed
    Score: 0.007
  116. Khurana JS, Wang J, Xu J, Koppetsch BS, Thomson TC, Nowosielska A, Li C, Zamore PD, Weng Z, Theurkauf WE. Adaptation to P element transposon invasion in Drosophila melanogaster. Cell. 2011 Dec 23; 147(7):1551-63.
    View in: PubMed
    Score: 0.007
  117. Han BW, Hung JH, Weng Z, Zamore PD, Ameres SL. The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Curr Biol. 2011 Nov 22; 21(22):1878-87.
    View in: PubMed
    Score: 0.007
  118. Zamore PD, Green MR. Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J. 1991 Jan; 10(1):207-14.
    View in: PubMed
    Score: 0.006
  119. Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 2010 Dec 23; 143(7):1084-96.
    View in: PubMed
    Score: 0.006
  120. Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, Perrimon N, Lai EC. Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Res. 2011 Feb; 21(2):203-15.
    View in: PubMed
    Score: 0.006
  121. Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, Flotte TR, Zamore PD, Gao G. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Mol Ther. 2011 Mar; 19(3):526-35.
    View in: PubMed
    Score: 0.006
  122. Tushir JS, Zamore PD, Zhang Z. SnapShot: mouse piRNAs, PIWI proteins, and the ping-pong cycle. Cell. 2009 Nov 13; 139(4):830-830.e1.
    View in: PubMed
    Score: 0.006
  123. Tushir JS, Zamore PD, Zhang Z. SnapShot: Fly piRNAs, PIWI proteins, and the ping-pong cycle. Cell. 2009 Oct 30; 139(3):634, 634.e1.
    View in: PubMed
    Score: 0.006
  124. Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana JS, Zhang F, Schultz N, Koppetsch BS, Nowosielska A, Seitz H, Zamore PD, Weng Z, Theurkauf WE. The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell. 2009 Sep 18; 138(6):1137-49.
    View in: PubMed
    Score: 0.006
  125. Kadener S, Menet JS, Sugino K, Horwich MD, Weissbein U, Nawathean P, Vagin VV, Zamore PD, Nelson SB, Rosbash M. A role for microRNAs in the Drosophila circadian clock. Genes Dev. 2009 Sep 15; 23(18):2179-91.
    View in: PubMed
    Score: 0.006
  126. Rossi J, Zamore P, Kay MA. Wandering eye for RNAi. Nat Med. 2008 Jun; 14(6):611.
    View in: PubMed
    Score: 0.005
  127. DiFiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, Yoder J, Reeves P, Pandey RK, Rajeev KG, Manoharan M, Sah DW, Zamore PD, Aronin N. Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):17204-9.
    View in: PubMed
    Score: 0.005
  128. Mallory AC, Reinhart BJ, Jones-Rhoades MW, Tang G, Zamore PD, Barton MK, Bartel DP. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. EMBO J. 2004 Aug 18; 23(16):3356-64.
    View in: PubMed
    Score: 0.004
  129. Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell. 2003 08; 2(4):209-17.
    View in: PubMed
    Score: 0.004
  130. Feldbr?gge M, Arizti P, Sullivan ML, Zamore PD, Belasco JG, Green PJ. Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells. Plant Mol Biol. 2002 May; 49(2):215-23.
    View in: PubMed
    Score: 0.004
  131. Wang X, Zamore PD, Hall TM. Crystal structure of a Pumilio homology domain. Mol Cell. 2001 Apr; 7(4):855-65.
    View in: PubMed
    Score: 0.003
  132. Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 1999 Dec 15; 13(24):3191-7.
    View in: PubMed
    Score: 0.003
  133. Curtis D, Treiber DK, Tao F, Zamore PD, Williamson JR, Lehmann R. A CCHC metal-binding domain in Nanos is essential for translational regulation. EMBO J. 1997 Feb 17; 16(4):834-43.
    View in: PubMed
    Score: 0.002
  134. Valc?rcel J, Singh R, Zamore PD, Green MR. The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature. 1993 Mar 11; 362(6416):171-5.
    View in: PubMed
    Score: 0.002
  135. Blacklow SC, Raines RT, Lim WA, Zamore PD, Knowles JR. Triosephosphate isomerase catalysis is diffusion controlled. Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR. Biochemistry. 1988 Feb 23; 27(4):1158-67.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.