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Connection

Phillip Zamore to MicroRNAs

This is a "connection" page, showing publications Phillip Zamore has written about MicroRNAs.
Connection Strength

7.861
  1. Jouravleva K, Vega-Badillo J, Zamore PD. Principles and pitfalls of high-throughput analysis of microRNA-binding thermodynamics and kinetics by RNA Bind-n-Seq. Cell Rep Methods. 2022 03 28; 2(3):100185.
    View in: PubMed
    Score: 0.471
  2. Wu PH, Zamore PD. To Degrade a MicroRNA, Destroy Its Argonaute Protein. Mol Cell. 2021 01 21; 81(2):223-225.
    View in: PubMed
    Score: 0.435
  3. Li C, Zamore PD. Preparation of Antisense Oligonucleotides to Inhibit miRNA Function. Cold Spring Harb Protoc. 2018 02 01; 2018(2).
    View in: PubMed
    Score: 0.354
  4. Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Cultured Mammalian Cells. Cold Spring Harb Protoc. 2018 02 01; 2018(2).
    View in: PubMed
    Score: 0.354
  5. Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Drosophila S2 Cells. Cold Spring Harb Protoc. 2018 02 01; 2018(2).
    View in: PubMed
    Score: 0.354
  6. Broderick JA, Zamore PD. Competitive endogenous RNAs cannot alter microRNA function in vivo. Mol Cell. 2014 Jun 05; 54(5):711-3.
    View in: PubMed
    Score: 0.275
  7. Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. EMBO J. 2014 Feb 18; 33(4):371-84.
    View in: PubMed
    Score: 0.268
  8. Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nat Rev Mol Cell Biol. 2013 Aug; 14(8):475-88.
    View in: PubMed
    Score: 0.257
  9. Flores-Jasso CF, Salomon WE, Zamore PD. Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates. RNA. 2013 Feb; 19(2):271-9.
    View in: PubMed
    Score: 0.248
  10. Wee LM, Flores-Jasso CF, Salomon WE, Zamore PD. Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties. Cell. 2012 Nov 21; 151(5):1055-67.
    View in: PubMed
    Score: 0.247
  11. Broderick JA, Zamore PD. MicroRNA therapeutics. Gene Ther. 2011 Dec; 18(12):1104-10.
    View in: PubMed
    Score: 0.221
  12. Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD. Target RNA-directed trimming and tailing of small silencing RNAs. Science. 2010 Jun 18; 328(5985):1534-9.
    View in: PubMed
    Score: 0.209
  13. Ghildiyal M, Xu J, Seitz H, Weng Z, Zamore PD. Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA. 2010 Jan; 16(1):43-56.
    View in: PubMed
    Score: 0.200
  14. Barringhaus KG, Zamore PD. MicroRNAs: regulating a change of heart. Circulation. 2009 Apr 28; 119(16):2217-24.
    View in: PubMed
    Score: 0.193
  15. Ghildiyal M, Zamore PD. Small silencing RNAs: an expanding universe. Nat Rev Genet. 2009 Feb; 10(2):94-108.
    View in: PubMed
    Score: 0.190
  16. Seitz H, Ghildiyal M, Zamore PD. Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies. Curr Biol. 2008 Jan 22; 18(2):147-51.
    View in: PubMed
    Score: 0.177
  17. Horwich MD, Zamore PD. Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nat Protoc. 2008; 3(10):1537-49.
    View in: PubMed
    Score: 0.176
  18. Matranga C, Zamore PD. Small silencing RNAs. Curr Biol. 2007 Sep 18; 17(18):R789-93.
    View in: PubMed
    Score: 0.172
  19. Du T, Zamore PD. Beginning to understand microRNA function. Cell Res. 2007 Aug; 17(8):661-3.
    View in: PubMed
    Score: 0.171
  20. F?rstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD. Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. Cell. 2007 Jul 27; 130(2):287-97.
    View in: PubMed
    Score: 0.171
  21. Tomari Y, Du T, Zamore PD. Sorting of Drosophila small silencing RNAs. Cell. 2007 Jul 27; 130(2):299-308.
    View in: PubMed
    Score: 0.171
  22. Seitz H, Zamore PD. Rethinking the microprocessor. Cell. 2006 Jun 02; 125(5):827-9.
    View in: PubMed
    Score: 0.158
  23. Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development. 2005 Nov; 132(21):4645-52.
    View in: PubMed
    Score: 0.151
  24. Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science. 2005 Sep 02; 309(5740):1519-24.
    View in: PubMed
    Score: 0.150
  25. F?rstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 2005 Jul; 3(7):e236.
    View in: PubMed
    Score: 0.147
  26. Tomari Y, Zamore PD. MicroRNA biogenesis: drosha can't cut it without a partner. Curr Biol. 2005 Jan 26; 15(2):R61-4.
    View in: PubMed
    Score: 0.144
  27. Jouravleva K, Zamore PD. A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals. Nat Rev Mol Cell Biol. 2025 May; 26(5):347-370.
    View in: PubMed
    Score: 0.144
  28. Hutv?gner G, Simard MJ, Mello CC, Zamore PD. Sequence-specific inhibition of small RNA function. PLoS Biol. 2004 Apr; 2(4):E98.
    View in: PubMed
    Score: 0.135
  29. Tang G, Zamore PD. Biochemical dissection of RNA silencing in plants. Methods Mol Biol. 2004; 257:223-44.
    View in: PubMed
    Score: 0.133
  30. Tang G, Reinhart BJ, Bartel DP, Zamore PD. A biochemical framework for RNA silencing in plants. Genes Dev. 2003 Jan 01; 17(1):49-63.
    View in: PubMed
    Score: 0.124
  31. Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall TMT, Zamore PD, Korostelev AA. Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol Cell. 2022 11 03; 82(21):4049-4063.e6.
    View in: PubMed
    Score: 0.122
  32. Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C, Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, Gao G. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Mol Ther. 2020 02 05; 28(2):422-430.
    View in: PubMed
    Score: 0.100
  33. Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism. Nat Immunol. 2016 06; 17(6):677-86.
    View in: PubMed
    Score: 0.078
  34. Ouimet M, Ediriweera HN, Gundra UM, Sheedy FJ, Ramkhelawon B, Hutchison SB, Rinehold K, van Solingen C, Fullerton MD, Cecchini K, Rayner KJ, Steinberg GR, Zamore PD, Fisher EA, Loke P, Moore KJ. MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis. J Clin Invest. 2015 Oct 26; 125(12):4334-48.
    View in: PubMed
    Score: 0.076
  35. Salomon WE, Jolly SM, Moore MJ, Zamore PD, Serebrov V. Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides. Cell. 2015 Jul 02; 162(1):84-95.
    View in: PubMed
    Score: 0.074
  36. Chou MT, Han BW, Hsiao CP, Zamore PD, Weng Z, Hung JH. Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs. Nucleic Acids Res. 2015 Sep 30; 43(17):e109.
    View in: PubMed
    Score: 0.073
  37. Moran Y, Fredman D, Praher D, Li XZ, Wee LM, Rentzsch F, Zamore PD, Technau U, Seitz H. Cnidarian microRNAs frequently regulate targets by cleavage. Genome Res. 2014 Apr; 24(4):651-63.
    View in: PubMed
    Score: 0.068
  38. Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell. 2012 Oct 26; 151(3):533-46.
    View in: PubMed
    Score: 0.061
  39. Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. Nat Methods. 2012 Mar 04; 9(4):403-9.
    View in: PubMed
    Score: 0.059
  40. Mueller C, Tang Q, Gruntman A, Blomenkamp K, Teckman J, Song L, Zamore PD, Flotte TR. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles. Mol Ther. 2012 03; 20(3):590-600.
    View in: PubMed
    Score: 0.058
  41. Han BW, Hung JH, Weng Z, Zamore PD, Ameres SL. The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Curr Biol. 2011 Nov 22; 21(22):1878-87.
    View in: PubMed
    Score: 0.057
  42. Cenik ES, Fukunaga R, Lu G, Dutcher R, Wang Y, Tanaka Hall TM, Zamore PD. Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease. Mol Cell. 2011 Apr 22; 42(2):172-84.
    View in: PubMed
    Score: 0.055
  43. Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, Perrimon N, Lai EC. Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Res. 2011 Feb; 21(2):203-15.
    View in: PubMed
    Score: 0.054
  44. Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, Flotte TR, Zamore PD, Gao G. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Mol Ther. 2011 Mar; 19(3):526-35.
    View in: PubMed
    Score: 0.054
  45. Ameres SL, Hung JH, Xu J, Weng Z, Zamore PD. Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins. RNA. 2011 Jan; 17(1):54-63.
    View in: PubMed
    Score: 0.054
  46. Kadener S, Menet JS, Sugino K, Horwich MD, Weissbein U, Nawathean P, Vagin VV, Zamore PD, Nelson SB, Rosbash M. A role for microRNAs in the Drosophila circadian clock. Genes Dev. 2009 Sep 15; 23(18):2179-91.
    View in: PubMed
    Score: 0.049
  47. Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell. 2005 Nov 18; 123(4):607-20.
    View in: PubMed
    Score: 0.038
  48. Mallory AC, Reinhart BJ, Jones-Rhoades MW, Tang G, Zamore PD, Barton MK, Bartel DP. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. EMBO J. 2004 Aug 18; 23(16):3356-64.
    View in: PubMed
    Score: 0.035
  49. Zamore PD. Plant RNAi: How a viral silencing suppressor inactivates siRNA. Curr Biol. 2004 Mar 09; 14(5):R198-200.
    View in: PubMed
    Score: 0.034
  50. Schwarz DS, Hutv?gner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell. 2003 Oct 17; 115(2):199-208.
    View in: PubMed
    Score: 0.033
  51. Hutv?gner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 2002 Sep 20; 297(5589):2056-60.
    View in: PubMed
    Score: 0.030
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.