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Connection

Janet Stavnezer to Immunoglobulin Class Switching

This is a "connection" page, showing publications Janet Stavnezer has written about Immunoglobulin Class Switching.
  1. Kadungure T, Ucher AJ, Linehan EK, Schrader CE, Stavnezer J. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination. PLoS One. 2015; 10(8):e0134397.
    View in: PubMed
    Score: 0.459
  2. Stavnezer J, Schrader CE. Response to comment on "IgH chain class switch recombination: mechanism and regulation". J Immunol. 2015 Mar 01; 194(5):2040.
    View in: PubMed
    Score: 0.444
  3. Stavnezer J, Schrader CE. IgH chain class switch recombination: mechanism and regulation. J Immunol. 2014 Dec 01; 193(11):5370-8.
    View in: PubMed
    Score: 0.437
  4. Ucher AJ, Linehan EK, Teebor GW, Schrader CE, Stavnezer J. The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells. PLoS One. 2012; 7(4):e36061.
    View in: PubMed
    Score: 0.364
  5. Ranjit S, Khair L, Linehan EK, Ucher AJ, Chakrabarti M, Schrader CE, Stavnezer J. AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected]. J Immunol. 2011 Sep 01; 187(5):2464-75.
    View in: PubMed
    Score: 0.347
  6. Guikema JE, Schrader CE, Brodsky MH, Linehan EK, Richards A, El Falaky N, Li DH, Sluss HK, Szomolanyi-Tsuda E, Stavnezer J. p53 represses class switch recombination to IgG2a through its antioxidant function. J Immunol. 2010 Jun 01; 184(11):6177-87.
    View in: PubMed
    Score: 0.318
  7. Stavnezer J, Bj?rkman A, Du L, Cagigi A, Pan-Hammarstr?m Q. Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching. Adv Immunol. 2010; 108:45-109.
    View in: PubMed
    Score: 0.311
  8. Schrader CE, Guikema JE, Wu X, Stavnezer J. The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch. Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12; 364(1517):645-52.
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    Score: 0.294
  9. Stavnezer J, Kang J. The surprising discovery that TGF beta specifically induces the IgA class switch. J Immunol. 2009 Jan 01; 182(1):5-7.
    View in: PubMed
    Score: 0.290
  10. Guikema JE, Schrader CE, Leus NG, Ucher A, Linehan EK, Werling U, Edelmann W, Stavnezer J. Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching. J Immunol. 2008 Dec 15; 181(12):8450-9.
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    Score: 0.289
  11. Stavnezer J, Guikema JE, Schrader CE. Mechanism and regulation of class switch recombination. Annu Rev Immunol. 2008; 26:261-92.
    View in: PubMed
    Score: 0.271
  12. Schrader CE, Guikema JE, Linehan EK, Selsing E, Stavnezer J. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J Immunol. 2007 Nov 01; 179(9):6064-71.
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    Score: 0.267
  13. Kaminski DA, Stavnezer J. Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b. Eur J Immunol. 2007 Jan; 37(1):240-51.
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    Score: 0.252
  14. Kaminski DA, Stavnezer J. Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells. J Immunol. 2006 Nov 01; 177(9):6025-9.
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    Score: 0.250
  15. Bradley SP, Kaminski DA, Peters AH, Jenuwein T, Stavnezer J. The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA. J Immunol. 2006 Jul 15; 177(2):1179-88.
    View in: PubMed
    Score: 0.244
  16. Stavnezer J, Schrader CE. Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination. Trends Genet. 2006 Jan; 22(1):23-8.
    View in: PubMed
    Score: 0.234
  17. Kaminski DA, Stavnezer J. Antibody class switching: uncoupling S region accessibility from transcription. Trends Genet. 2004 Aug; 20(8):337-40.
    View in: PubMed
    Score: 0.213
  18. Stavnezer J, Amemiya CT. Evolution of isotype switching. Semin Immunol. 2004 Aug; 16(4):257-75.
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    Score: 0.213
  19. Schrader CE, Vardo J, Linehan E, Twarog MZ, Niedernhofer LJ, Hoeijmakers JH, Stavnezer J. Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions. J Exp Med. 2004 Aug 02; 200(3):321-30.
    View in: PubMed
    Score: 0.213
  20. Schrader CE, Vardo J, Stavnezer J. Mlh1 can function in antibody class switch recombination independently of Msh2. J Exp Med. 2003 May 19; 197(10):1377-83.
    View in: PubMed
    Score: 0.196
  21. Schrader CE, Vardo J, Stavnezer J. Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J Exp Med. 2002 Feb 04; 195(3):367-73.
    View in: PubMed
    Score: 0.180
  22. Schrader CE, Edelmann W, Kucherlapati R, Stavnezer J. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. J Exp Med. 1999 Aug 02; 190(3):323-30.
    View in: PubMed
    Score: 0.151
  23. Qiu G, Harriman GR, Stavnezer J. Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice. Int Immunol. 1999 Jan; 11(1):37-46.
    View in: PubMed
    Score: 0.145
  24. Lin SC, Wortis HH, Stavnezer J. The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins. Mol Cell Biol. 1998 Sep; 18(9):5523-32.
    View in: PubMed
    Score: 0.142
  25. Lin SC, Stavnezer J. Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter. Mol Cell Biol. 1996 Sep; 16(9):4591-603.
    View in: PubMed
    Score: 0.123
  26. Stavnezer J. Antibody class switching. Adv Immunol. 1996; 61:79-146.
    View in: PubMed
    Score: 0.118
  27. Stavnezer J. Regulation of antibody production and class switching by TGF-beta. J Immunol. 1995 Aug 15; 155(4):1647-51.
    View in: PubMed
    Score: 0.115
  28. Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J. A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nat Immunol. 2013 Nov; 14(11):1183-1189.
    View in: PubMed
    Score: 0.101
  29. Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J. DNA polymerases ? and ? do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations. DNA Repair (Amst). 2013 Dec; 12(12):1087-93.
    View in: PubMed
    Score: 0.101
  30. Hasham MG, Snow KJ, Donghia NM, Branca JA, Lessard MD, Stavnezer J, Shopland LS, Mills KD. Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase. J Immunol. 2012 Sep 01; 189(5):2374-82.
    View in: PubMed
    Score: 0.093
  31. Stavnezer J. Complex regulation and function of activation-induced cytidine deaminase. Trends Immunol. 2011 May; 32(5):194-201.
    View in: PubMed
    Score: 0.085
  32. Eccleston J, Schrader CE, Yuan K, Stavnezer J, Selsing E. Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats. J Immunol. 2009 Jul 15; 183(2):1222-8.
    View in: PubMed
    Score: 0.075
  33. Guikema JE, Linehan EK, Tsuchimoto D, Nakabeppu Y, Strauss PR, Stavnezer J, Schrader CE. APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. J Exp Med. 2007 Nov 26; 204(12):3017-26.
    View in: PubMed
    Score: 0.067
  34. Min IM, Rothlein LR, Schrader CE, Stavnezer J, Selsing E. Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2. J Exp Med. 2005 Jun 20; 201(12):1885-90.
    View in: PubMed
    Score: 0.057
  35. Min IM, Schrader CE, Vardo J, Luby TM, D'Avirro N, Stavnezer J, Selsing E. The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2. Immunity. 2003 Oct; 19(4):515-24.
    View in: PubMed
    Score: 0.050
  36. Staszewski O, Baker RE, Ucher AJ, Martier R, Stavnezer J, Guikema JE. Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells. Mol Cell. 2011 Jan 21; 41(2):232-42.
    View in: PubMed
    Score: 0.021
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.