Header Logo

Connection

Co-Authors

Back to Details
This is a "connection" page, showing publications co-authored by Dale Greiner and Leonard Shultz.
Dale Greiner
Connection Strength
10.606
Leonard Shultz
  1. Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL. Subcapsular transplantation of tissue in the kidney. Cold Spring Harb Protoc. 2014 Jul 01; 2014(7):737-40.
    View in: PubMed
    Score: 0.477
  2. Shultz LD, Goodwin N, Ishikawa F, Hosur V, Lyons BL, Greiner DL. Human cancer growth and therapy in immunodeficient mouse models. Cold Spring Harb Protoc. 2014 Jul 01; 2014(7):694-708.
    View in: PubMed
    Score: 0.477
  3. Shultz LD, Brehm MA, Garcia-Martinez JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012 Nov; 12(11):786-98.
    View in: PubMed
    Score: 0.424
  4. Shultz LD, Brehm MA, Bavari S, Greiner DL. Humanized mice as a preclinical tool for infectious disease and biomedical research. Ann N Y Acad Sci. 2011 Dec; 1245:50-4.
    View in: PubMed
    Score: 0.399
  5. Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD. Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci. 2011 Dec; 1245:55-8.
    View in: PubMed
    Score: 0.399
  6. Shultz LD, Pearson T, King M, Giassi L, Carney L, Gott B, Lyons B, Rossini AA, Greiner DL. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. Ann N Y Acad Sci. 2007 Apr; 1103:77-89.
    View in: PubMed
    Score: 0.287
  7. Shultz LD, Ishikawa F, Greiner DL. Humanized mice in translational biomedical research. Nat Rev Immunol. 2007 Feb; 7(2):118-30.
    View in: PubMed
    Score: 0.286
  8. Shultz LD, Banuelos S, Lyons B, Samuels R, Burzenski L, Gott B, Lang P, Leif J, Appel M, Rossini A, Greiner DL. NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment. Transplantation. 2003 Oct 15; 76(7):1036-42.
    View in: PubMed
    Score: 0.227
  9. Shultz LD, Banuelos SJ, Leif J, Appel MC, Cunningham M, Ballen K, Burzenski L, Greiner DL. Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells. Exp Hematol. 2003 Jun; 31(6):551-8.
    View in: PubMed
    Score: 0.221
  10. Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S, Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner DL. NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for engraftment of human hematolymphoid cells, HIV infection, and adoptive transfer of NOD mouse diabetogenic T cells. J Immunol. 2000 Mar 01; 164(5):2496-507.
    View in: PubMed
    Score: 0.177
  11. Shultz LD, Keck J, Burzenski L, Jangalwe S, Vaidya S, Greiner DL, Brehm MA. Humanized mouse models of immunological diseases and precision medicine. Mamm Genome. 2019 06; 30(5-6):123-142.
    View in: PubMed
    Score: 0.165
  12. Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression. FASEB J. 2019 03; 33(3):3137-3151.
    View in: PubMed
    Score: 0.161
  13. Greiner DL, Hesselton RA, Shultz LD. SCID mouse models of human stem cell engraftment. Stem Cells. 1998; 16(3):166-77.
    View in: PubMed
    Score: 0.152
  14. Shultz LD, Rajan TV, Greiner DL. Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency. Trends Biotechnol. 1997 Aug; 15(8):302-7.
    View in: PubMed
    Score: 0.148
  15. Verma MK, Clemens J, Burzenski L, Sampson SB, Brehm MA, Greiner DL, Shultz LD. A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo. J Immunol Methods. 2017 07; 446:47-53.
    View in: PubMed
    Score: 0.145
  16. Walsh NC, Kenney LL, Jangalwe S, Aryee KE, Greiner DL, Brehm MA, Shultz LD. Humanized Mouse Models of Clinical Disease. Annu Rev Pathol. 2017 Jan 24; 12:187-215.
    View in: PubMed
    Score: 0.141
  17. Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. J Immunol. 1995 Jan 01; 154(1):180-91.
    View in: PubMed
    Score: 0.124
  18. Brehm MA, Wiles MV, Greiner DL, Shultz LD. Generation of improved humanized mouse models for human infectious diseases. J Immunol Methods. 2014 Aug; 410:3-17.
    View in: PubMed
    Score: 0.117
  19. Brehm MA, Shultz LD, Luban J, Greiner DL. Overcoming current limitations in humanized mouse research. J Infect Dis. 2013 Nov; 208 Suppl 2:S125-30.
    View in: PubMed
    Score: 0.114
  20. Brehm MA, Jouvet N, Greiner DL, Shultz LD. Humanized mice for the study of infectious diseases. Curr Opin Immunol. 2013 Aug; 25(4):428-35.
    View in: PubMed
    Score: 0.111
  21. Brehm MA, Powers AC, Shultz LD, Greiner DL. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med. 2012 May; 2(5):a007757.
    View in: PubMed
    Score: 0.103
  22. Greiner DL, Rajan TV, Shultz LD. Animal models for immunodeficiency diseases. Immunol Today. 1992 Apr; 13(4):116-7.
    View in: PubMed
    Score: 0.102
  23. Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul; 39(5):645-51.
    View in: PubMed
    Score: 0.101
  24. Brehm MA, Racki WJ, Leif J, Burzenski L, Hosur V, Wetmore A, Gott B, Herlihy M, Ignotz R, Dunn R, Shultz LD, Greiner DL. Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2r? null mice is enhanced by transgenic expression of membrane-bound human SCF. Blood. 2012 Mar 22; 119(12):2778-88.
    View in: PubMed
    Score: 0.101
  25. Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Shultz LD, Hnatowich DJ, Greiner DL. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 06; 8(3):767-73.
    View in: PubMed
    Score: 0.096
  26. Brehm MA, Bortell R, Diiorio P, Leif J, Laning J, Cuthbert A, Yang C, Herlihy M, Burzenski L, Gott B, Foreman O, Powers AC, Greiner DL, Shultz LD. Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice. Diabetes. 2010 Sep; 59(9):2265-70.
    View in: PubMed
    Score: 0.090
  27. Brehm MA, Shultz LD, Greiner DL. Humanized mouse models to study human diseases. Curr Opin Endocrinol Diabetes Obes. 2010 Apr; 17(2):120-5.
    View in: PubMed
    Score: 0.089
  28. Racki WJ, Covassin L, Brehm M, Pino S, Ignotz R, Dunn R, Laning J, Graves SK, Rossini AA, Shultz LD, Greiner DL. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation. 2010 Mar 15; 89(5):527-36.
    View in: PubMed
    Score: 0.089
  29. Brehm MA, Cuthbert A, Yang C, Miller DM, DiIorio P, Laning J, Burzenski L, Gott B, Foreman O, Kavirayani A, Herlihy M, Rossini AA, Shultz LD, Greiner DL. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. Clin Immunol. 2010 Apr; 135(1):84-98.
    View in: PubMed
    Score: 0.088
  30. Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.
    View in: PubMed
    Score: 0.087
  31. King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol. 2009 Jul; 157(1):104-18.
    View in: PubMed
    Score: 0.084
  32. Miller DM, Thornley TB, Pearson T, Kruger AJ, Yamazaki M, Shultz LD, Welsh RM, Brehm MA, Rossini AA, Greiner DL. TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade. J Immunol. 2009 May 01; 182(9):5547-59.
    View in: PubMed
    Score: 0.083
  33. King M, Pearson T, Rossini AA, Shultz LD, Greiner DL. Humanized mice for the study of type 1 diabetes and beta cell function. Ann N Y Acad Sci. 2008 Dec; 1150:46-53.
    View in: PubMed
    Score: 0.081
  34. Mangada J, Pearson T, Brehm MA, Wicker LS, Peterson LB, Shultz LD, Serreze DV, Rossini AA, Greiner DL. Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice. Diabetes. 2009 Jan; 58(1):165-73.
    View in: PubMed
    Score: 0.081
  35. Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment. Clin Exp Immunol. 2008 Nov; 154(2):270-84.
    View in: PubMed
    Score: 0.080
  36. Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008 Aug; 233(8):997-1012.
    View in: PubMed
    Score: 0.079
  37. Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL. A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function. Diabetologia. 2008 Aug; 51(8):1449-56.
    View in: PubMed
    Score: 0.079
  38. Pearson T, Greiner DL, Shultz LD. Creation of "humanized" mice to study human immunity. Curr Protoc Immunol. 2008 May; Chapter 15:15.21.1-15.21.21.
    View in: PubMed
    Score: 0.078
  39. Pearson T, Greiner DL, Shultz LD. Humanized SCID mouse models for biomedical research. Curr Top Microbiol Immunol. 2008; 324:25-51.
    View in: PubMed
    Score: 0.076
  40. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clin Immunol. 2008 Mar; 126(3):303-14.
    View in: PubMed
    Score: 0.076
  41. Thornley TB, Phillips NE, Beaudette-Zlatanova BC, Markees TG, Bahl K, Brehm MA, Shultz LD, Kurt-Jones EA, Mordes JP, Welsh RM, Rossini AA, Greiner DL. Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance. J Immunol. 2007 Nov 15; 179(10):6620-9.
    View in: PubMed
    Score: 0.075
  42. Yamazaki M, Pearson T, Brehm MA, Miller DM, Mangada JA, Markees TG, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Different mechanisms control peripheral and central tolerance in hematopoietic chimeric mice. Am J Transplant. 2007 Jul; 7(7):1710-21.
    View in: PubMed
    Score: 0.073
  43. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. Ann N Y Acad Sci. 2007 Apr; 1103:90-3.
    View in: PubMed
    Score: 0.072
  44. Thornley TB, Brehm MA, Markees TG, Shultz LD, Mordes JP, Welsh RM, Rossini AA, Greiner DL. TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol. 2006 Feb 01; 176(3):1561-70.
    View in: PubMed
    Score: 0.067
  45. Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol. 2005 May 15; 174(10):6477-89.
    View in: PubMed
    Score: 0.063
  46. Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Sellick K, Spears E, Poffenberger G, Schornack AMR, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners. Mol Metab. 2024 Dec; 90:102050.
    View in: PubMed
    Score: 0.061
  47. Banuelos SJ, Markees TG, Phillips NE, Appel MC, Cuthbert A, Leif J, Mordes JP, Shultz LD, Rossini AA, Greiner DL. Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms. Transplantation. 2004 Sep 15; 78(5):660-7.
    View in: PubMed
    Score: 0.061
  48. Coate KC, Dai C, Singh A, Stanley J, Covington BA, Bradley A, Oladipupo F, Gong Y, Wisniewski S, Spears E, Poffenberger G, Bustabad A, Rodgers T, Dey N, Shultz LD, Greiner DL, Yan H, Powers AC, Chen W, Dean ED. Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners. bioRxiv. 2024 Aug 07.
    View in: PubMed
    Score: 0.060
  49. Pearson T, Weiser P, Markees TG, Serreze DV, Wicker LS, Peterson LB, Cumisky AM, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3. Diabetes. 2004 Aug; 53(8):1972-8.
    View in: PubMed
    Score: 0.060
  50. Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 Sep; 54(9):e2350949.
    View in: PubMed
    Score: 0.059
  51. Stepien TA, Singletary LA, Guerra FE, Karlinsey JE, Libby SJ, Jaslow SL, Gaggioli MR, Gibbs KD, Ko DC, Brehm MA, Greiner DL, Shultz LD, Fang FC. Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages. mBio. 2024 Apr 10; 15(4):e0045424.
    View in: PubMed
    Score: 0.059
  52. Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE, Parker SCJ, Powers AC, Brissova M. Genetic risk converges on regulatory networks mediating early type 2 diabetes. Nature. 2023 Dec; 624(7992):621-629.
    View in: PubMed
    Score: 0.057
  53. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms? Ann N Y Acad Sci. 2003 Nov; 1005:148-56.
    View in: PubMed
    Score: 0.057
  54. Pearson T, Markees TG, Serreze DV, Pierce MA, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice. Rev Endocr Metab Disord. 2003 Sep; 4(3):255-61.
    View in: PubMed
    Score: 0.056
  55. Pearson T, Markees TG, Serreze DV, Pierce MA, Marron MP, Wicker LS, Peterson LB, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Genetic disassociation of autoimmunity and resistance to costimulation blockade-induced transplantation tolerance in nonobese diabetic mice. J Immunol. 2003 Jul 01; 171(1):185-95.
    View in: PubMed
    Score: 0.056
  56. Doloff JC, Ma M, Sadraei A, Tam HH, Farah S, Hollister-Lock J, Vegas AJ, Veiseh O, Quiroz VM, Rakoski A, Aresta-DaSilva S, Bader AR, Griffin M, Weir GC, Brehm MA, Shultz LD, Langer R, Greiner DL, Anderson DG. Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response. Sci Adv. 2023 06 16; 9(24):eade9488.
    View in: PubMed
    Score: 0.056
  57. Yang J, Jiao J, Draheim KM, Yang G, Yang H, Yao LC, Shultz LD, Greiner DL, Rajagopal D, Vessillier S, Maier CC, Mohanan S, Cai D, Cheng M, Brehm MA, Keck JG. Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model. FASEB J. 2023 06; 37(6):e22995.
    View in: PubMed
    Score: 0.055
  58. Aryee KE, Shultz LD, Burzenski LM, Greiner DL, Brehm MA. NOD-scid IL2r?null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. J Leukoc Biol. 2023 05 02; 113(5):418-433.
    View in: PubMed
    Score: 0.055
  59. Chuprin J, Buettner H, Seedhom MO, Greiner DL, Keck JG, Ishikawa F, Shultz LD, Brehm MA. Humanized mouse models for immuno-oncology research. Nat Rev Clin Oncol. 2023 03; 20(3):192-206.
    View in: PubMed
    Score: 0.054
  60. Jung S, Jiang L, Zhao J, Shultz LD, Greiner DL, Bae M, Li X, Ordikhani F, Kuai R, Joseph J, Kasinath V, Elmaleh DR, Abdi R. Clathrin light chain-conjugated drug delivery for cancer. Bioeng Transl Med. 2023 Jan; 8(1):e10273.
    View in: PubMed
    Score: 0.053
  61. Aryee KE, Burzenski LM, Yao LC, Keck JG, Greiner DL, Shultz LD, Brehm MA. Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15. FASEB J. 2022 09; 36(9):e22476.
    View in: PubMed
    Score: 0.053
  62. Christianson SW, Greiner DL, Deluca D, Leif J, Phillips NE, Hayes SM, Hayashi S, Joliat MJ, Lyons BL, Shultz LD. T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7. J Autoimmun. 2002 Mar; 18(2):119-30.
    View in: PubMed
    Score: 0.051
  63. Stepien TA, Libby SJ, Karlinsey JE, Brehm MA, Greiner DL, Shultz LD, Brabb T, Fang FC. Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model. Methods Mol Biol. 2022; 2427:215-234.
    View in: PubMed
    Score: 0.050
  64. Jiang L, Wang YJ, Zhao J, Uehara M, Hou Q, Kasinath V, Ichimura T, Banouni N, Dai L, Li X, Greiner DL, Shultz LD, Zhang X, Sun ZJ, Curtin I, Vangos NE, Yeoh ZC, Geffken EA, Seo HS, Liu ZX, Heffron GJ, Shah K, Dhe-Paganon S, Abdi R. Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy. Cell. 2020 11 25; 183(5):1219-1233.e18.
    View in: PubMed
    Score: 0.047
  65. Ye C, Yang H, Cheng M, Shultz LD, Greiner DL, Brehm MA, Keck JG. A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome. FASEB J. 2020 09; 34(9):12963-12975.
    View in: PubMed
    Score: 0.046
  66. Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin Does Not Directly Affect Human a or ? Cells. Endocrinology. 2020 08 01; 161(8).
    View in: PubMed
    Score: 0.045
  67. Wagar EJ, Cromwell MA, Shultz LD, Woda BA, Sullivan JL, Hesselton RM, Greiner DL. Regulation of human cell engraftment and development of EBV-related lymphoproliferative disorders in Hu-PBL-scid mice. J Immunol. 2000 Jul 01; 165(1):518-27.
    View in: PubMed
    Score: 0.045
  68. Dai C, Walker JT, Shostak A, Padgett A, Spears E, Wisniewski S, Poffenberger G, Aramandla R, Dean ED, Prasad N, Levy SE, Greiner DL, Shultz LD, Bottino R, Powers AC. Tacrolimus- and sirolimus-induced human ? cell dysfunction is reversible and preventable. JCI Insight. 2020 01 16; 5(1).
    View in: PubMed
    Score: 0.044
  69. Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. FASEB J. 2020 01; 34(1):1901-1911.
    View in: PubMed
    Score: 0.044
  70. Karlinsey JE, Stepien TA, Mayho M, Singletary LA, Bingham-Ramos LK, Brehm MA, Greiner DL, Shultz LD, Gallagher LA, Bawn M, Kingsley RA, Libby SJ, Fang FC. Genome-wide Analysis of Salmonella enterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. Cell Host Microbe. 2019 09 11; 26(3):426-434.e6.
    View in: PubMed
    Score: 0.043
  71. Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019; 180(2):91-102.
    View in: PubMed
    Score: 0.043
  72. Gawron MA, Duval M, Carbone C, Jaiswal S, Wallace A, Martin JC, Dauphin A, Brehm MA, Greiner DL, Shultz LD, Luban J, Cavacini LA. Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1. J Immunol. 2019 02 01; 202(3):799-804.
    View in: PubMed
    Score: 0.041
  73. Bahmani B, Uehara M, Ordikhani F, Li X, Jiang L, Banouni N, Ichimura T, Kasinath V, Eskandari SK, Annabi N, Bromberg JS, Shultz LD, Greiner DL, Abdi R. Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery. EBioMedicine. 2018 Dec; 38:79-88.
    View in: PubMed
    Score: 0.041
  74. Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, S?vigny J, Powers AC. Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic ? Cells for In?Vitro and In?Vivo Analysis. Cell Metab. 2019 03 05; 29(3):745-754.e4.
    View in: PubMed
    Score: 0.040
  75. Gordon EJ, Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Rossini AA, Greiner DL. Prolonged survival of rat islet and skin xenografts in mice treated with donor splenocytes and anti-CD154 monoclonal antibody. Diabetes. 1998 Aug; 47(8):1199-206.
    View in: PubMed
    Score: 0.040
  76. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676.
    View in: PubMed
    Score: 0.039
  77. Wang M, Yao LC, Cheng M, Cai D, Martinek J, Pan CX, Shi W, Ma AH, De Vere White RW, Airhart S, Liu ET, Banchereau J, Brehm MA, Greiner DL, Shultz LD, Palucka K, Keck JG. Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy. FASEB J. 2018 03; 32(3):1537-1549.
    View in: PubMed
    Score: 0.038
  78. Foy TM, McIlraith M, Masters SR, Dunn JJ, Rossini AA, Shultz LD, Hesselton RA, Wagar EJ, Lipsky PE, Noelle RJ, Greiner DL. Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice. Cell Transplant. 1998 Jan-Feb; 7(1):25-35.
    View in: PubMed
    Score: 0.038
  79. Borel F, Tang Q, Gernoux G, Greer C, Wang Z, Barzel A, Kay MA, Shultz LD, Greiner DL, Flotte TR, Brehm MA, Mueller C. Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of a-1 Antitrypsin Deficiency. Mol Ther. 2017 11 01; 25(11):2477-2489.
    View in: PubMed
    Score: 0.037
  80. Dai C, Hang Y, Shostak A, Poffenberger G, Hart N, Prasad N, Phillips N, Levy SE, Greiner DL, Shultz LD, Bottino R, Kim SK, Powers AC. Age-dependent human ? cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. J Clin Invest. 2017 Oct 02; 127(10):3835-3844.
    View in: PubMed
    Score: 0.037
  81. Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Rep. 2017 Aug 22; 20(8):1978-1990.
    View in: PubMed
    Score: 0.037
  82. Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ. mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors. J Clin Invest. 2017 Jun 01; 127(6):2433-2437.
    View in: PubMed
    Score: 0.036
  83. Christianson SW, Greiner DL, Hesselton RA, Leif JH, Wagar EJ, Schweitzer IB, Rajan TV, Gott B, Roopenian DC, Shultz LD. Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. J Immunol. 1997 Apr 15; 158(8):3578-86.
    View in: PubMed
    Score: 0.036
  84. Moser J, van Ark J, van Dijk MC, Greiner DL, Shultz LD, van Goor H, Hillebrands JL. Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury. Sci Rep. 2016 10 19; 6:35387.
    View in: PubMed
    Score: 0.035
  85. Boudreau JE, Liu XR, Zhao Z, Zhang A, Shultz LD, Greiner DL, Dupont B, Hsu KC. Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I. Immunity. 2016 08 16; 45(2):280-91.
    View in: PubMed
    Score: 0.034
  86. Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. Cell Immunol. 1996 Aug 01; 171(2):186-99.
    View in: PubMed
    Score: 0.034
  87. Ali R, Babad J, Follenzi A, Gebe JA, Brehm MA, Nepom GT, Shultz LD, Greiner DL, DiLorenzo TP. Genetically modified human CD4(+) T cells can be evaluated in?vivo without lethal graft-versus-host disease. Immunology. 2016 08; 148(4):339-51.
    View in: PubMed
    Score: 0.034
  88. Mercado-Lubo R, Zhang Y, Zhao L, Rossi K, Wu X, Zou Y, Castillo A, Leonard J, Bortell R, Greiner DL, Shultz LD, Han G, McCormick BA. A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours. Nat Commun. 2016 07 25; 7:12225.
    View in: PubMed
    Score: 0.034
  89. Rajan TV, Greiner DL, Yates JA, Shultz LD. Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression. Acta Trop. 1996 May; 61(3):267-71.
    View in: PubMed
    Score: 0.034
  90. Dai C, Kayton NS, Shostak A, Poffenberger G, Cyphert HA, Aramandla R, Thompson C, Papagiannis IG, Emfinger C, Shiota M, Stafford JM, Greiner DL, Herrera PL, Shultz LD, Stein R, Powers AC. Stress-impaired transcription factor expression and insulin secretion in transplanted human islets. J Clin Invest. 2016 05 02; 126(5):1857-70.
    View in: PubMed
    Score: 0.034
  91. Bryce PJ, Falahati R, Kenney LL, Leung J, Bebbington C, Tomasevic N, Krier RA, Hsu CL, Shultz LD, Greiner DL, Brehm MA. Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis. J Allergy Clin Immunol. 2016 09; 138(3):769-779.
    View in: PubMed
    Score: 0.034
  92. Goel HL, Pursell B, Shultz LD, Greiner DL, Brekken RA, Vander Kooi CW, Mercurio AM. P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. Cell Rep. 2016 Mar 08; 14(9):2193-2208.
    View in: PubMed
    Score: 0.033
  93. Greiner DL, Shultz LD, Deluca D, Leif JH, Christianson SW, Hesselton RM. HIV-1 infectivity of human T cells in a human/murine chimeric fetal thymic organ culture system. In Vivo. 1996 Jan-Feb; 10(1):33-7.
    View in: PubMed
    Score: 0.033
  94. Hasgur S, Aryee KE, Shultz LD, Greiner DL, Brehm MA. Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells. Methods Mol Biol. 2016; 1438:67-78.
    View in: PubMed
    Score: 0.033
  95. Friedline RH, Ko HJ, Jung DY, Lee Y, Bortell R, Dagdeviren S, Patel PR, Hu X, Inashima K, Kearns C, Tsitsilianos N, Shafiq U, Shultz LD, Lee KW, Greiner DL, Kim JK. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance. FASEB J. 2016 Mar; 30(3):1328-38.
    View in: PubMed
    Score: 0.033
  96. Serreze DV, Leiter EH, Hanson MS, Christianson SW, Shultz LD, Hesselton RM, Greiner DL. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells. Diabetes. 1995 Dec; 44(12):1392-8.
    View in: PubMed
    Score: 0.033
  97. Kenney LL, Shultz LD, Greiner DL, Brehm MA. Humanized Mouse Models for Transplant Immunology. Am J Transplant. 2016 Feb; 16(2):389-97.
    View in: PubMed
    Score: 0.033
  98. Jurczyk A, Nowosielska A, Przewozniak N, Aryee KE, DiIorio P, Blodgett D, Yang C, Campbell-Thompson M, Atkinson M, Shultz L, Rittenhouse A, Harlan D, Greiner D, Bortell R. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic ?-cell function via glycogen synthase kinase-3?. FASEB J. 2016 Feb; 30(2):983-93.
    View in: PubMed
    Score: 0.033
  99. Sewald X, Ladinsky MS, Uchil PD, Beloor J, Pi R, Herrmann C, Motamedi N, Murooka TT, Brehm MA, Greiner DL, Shultz LD, Mempel TR, Bjorkman PJ, Kumar P, Mothes W. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection. Science. 2015 Oct 30; 350(6260):563-567.
    View in: PubMed
    Score: 0.033
  100. Hesselton RM, Greiner DL, Mordes JP, Rajan TV, Sullivan JL, Shultz LD. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. J Infect Dis. 1995 Oct; 172(4):974-82.
    View in: PubMed
    Score: 0.033
  101. Li S, Ling C, Zhong L, Li M, Su Q, He R, Tang Q, Greiner DL, Shultz LD, Brehm MA, Flotte TR, Mueller C, Srivastava A, Gao G. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. Mol Ther. 2015 Dec; 23(12):1867-76.
    View in: PubMed
    Score: 0.033
  102. Yang C, Loehn M, Jurczyk A, Przewozniak N, Leehy L, Herrera PL, Shultz LD, Greiner DL, Harlan DM, Bortell R. Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets. Diabetes Metab Syndr Obes. 2015; 8:387-98.
    View in: PubMed
    Score: 0.032
  103. Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015 Oct 01; 195(7):3011-9.
    View in: PubMed
    Score: 0.032
  104. Rajan TV, Shultz LD, Yates J, Greiner DL. B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. J Parasitol. 1995 Jun; 81(3):490-3.
    View in: PubMed
    Score: 0.032
  105. Samanta S, Sun H, Goel HL, Pursell B, Chang C, Khan A, Greiner DL, Cao S, Lim E, Shultz LD, Mercurio AM. IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG. Oncogene. 2016 Mar 03; 35(9):1111-21.
    View in: PubMed
    Score: 0.032
  106. Greiner DL, Shultz LD, Yates J, Appel MC, Perdrizet G, Hesselton RM, Schweitzer I, Beamer WG, Shultz KL, Pelsue SC, et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol. 1995 Apr; 146(4):888-902.
    View in: PubMed
    Score: 0.031
  107. Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP. Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice. Clin Exp Immunol. 2015 Mar; 179(3):398-413.
    View in: PubMed
    Score: 0.031
  108. Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6B?1 integrin to sustain breast cancer stem cells. Genes Dev. 2015 Jan 01; 29(1):1-6.
    View in: PubMed
    Score: 0.031
  109. Gallagher GR, Brehm MA, Finberg RW, Barton BA, Shultz LD, Greiner DL, Bortell R, Wang JP. Viral infection of engrafted human islets leads to diabetes. Diabetes. 2015 Apr; 64(4):1358-69.
    View in: PubMed
    Score: 0.031
  110. Jaiswal S, Smith K, Ramirez A, Woda M, Pazoles P, Shultz LD, Greiner DL, Brehm MA, Mathew A. Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice. Exp Biol Med (Maywood). 2015 Jan; 240(1):67-78.
    View in: PubMed
    Score: 0.030
  111. Trabucco SE, Gerstein RM, Evens AM, Bradner JE, Shultz LD, Greiner DL, Zhang H. Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma. Clin Cancer Res. 2015 Jan 01; 21(1):113-22.
    View in: PubMed
    Score: 0.030
  112. Rajan TV, Nelson FK, Killeen N, Shultz LD, Yates JA, Bailis JM, Littman DR, Greiner DL. CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. Exp Parasitol. 1994 Jun; 78(4):352-60.
    View in: PubMed
    Score: 0.030
  113. Maykel J, Liu JH, Li H, Shultz LD, Greiner DL, Houghton J. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer. Dig Dis Sci. 2014 Jun; 59(6):1169-79.
    View in: PubMed
    Score: 0.030
  114. Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM. Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 2014 May 08; 7(3):747-61.
    View in: PubMed
    Score: 0.029
  115. Rajan TV, Nelson FK, Shultz LD, Shultz KL, Beamer WG, Yates J, Greiner DL. Influence of gonadal steroids on susceptibility to Brugia malayi in scid mice. Acta Trop. 1994 Apr; 56(4):307-14.
    View in: PubMed
    Score: 0.029
  116. Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE. An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nat Genet. 2014 Apr; 46(4):364-70.
    View in: PubMed
    Score: 0.029
  117. Hayes SM, Shultz LD, Greiner DL. Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients. Cell Immunol. 1994 Feb; 153(2):344-55.
    View in: PubMed
    Score: 0.029
  118. Roderick JE, Tesell J, Shultz LD, Brehm MA, Greiner DL, Harris MH, Silverman LB, Sallan SE, Gutierrez A, Look AT, Qi J, Bradner JE, Kelliher MA. c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells. Blood. 2014 Feb 13; 123(7):1040-50.
    View in: PubMed
    Score: 0.029
  119. Jurczyk A, Diiorio P, Brostowin D, Leehy L, Yang C, Urano F, Harlan DM, Shultz LD, Greiner DL, Bortell R. Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2r?(null) mice treated with alogliptin. Diabetes Metab Syndr Obes. 2013; 6:493-9.
    View in: PubMed
    Score: 0.029
  120. Lee J, Brehm MA, Greiner D, Shultz LD, Kornfeld H. Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice. BMC Immunol. 2013 Dec 07; 14:53.
    View in: PubMed
    Score: 0.029
  121. Schleifman EB, McNeer NA, Jackson A, Yamtich J, Brehm MA, Shultz LD, Greiner DL, Kumar P, Saltzman WM, Glazer PM. Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Mol Ther Nucleic Acids. 2013 Nov 19; 2:e135.
    View in: PubMed
    Score: 0.029
  122. Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G. Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. Nucl Med Biol. 2014 Jan; 41(1):127-31.
    View in: PubMed
    Score: 0.028
  123. Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013 Apr; 5(4):488-508.
    View in: PubMed
    Score: 0.027
  124. Hickey RD, Galivo F, Schug J, Brehm MA, Haft A, Wang Y, Benedetti E, Gu G, Magnuson MA, Shultz LD, Lagasse E, Greiner DL, Kaestner KH, Grompe M. Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res. 2013 Jul; 11(1):503-15.
    View in: PubMed
    Score: 0.027
  125. Unger WW, Pearson T, Abreu JR, Laban S, van der Slik AR, der Kracht SM, Kester MG, Serreze DV, Shultz LD, Griffioen M, Drijfhout JW, Greiner DL, Roep BO. Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice. PLoS One. 2012; 7(11):e49213.
    View in: PubMed
    Score: 0.027
  126. McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W, Glazer PM. Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Ther. 2013 Jun; 20(6):658-69.
    View in: PubMed
    Score: 0.027
  127. Rajan TV, Nelson FK, Shultz LD, Koller BH, Greiner DL. CD8+ T lymphocytes are not required for murine resistance to human filarial parasites. J Parasitol. 1992 Aug; 78(4):744-6.
    View in: PubMed
    Score: 0.026
  128. Jaiswal S, Pazoles P, Woda M, Shultz LD, Greiner DL, Brehm MA, Mathew A. Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice. Immunology. 2012 Jul; 136(3):334-43.
    View in: PubMed
    Score: 0.026
  129. Hayes SM, Shultz LD, Greiner DL. Thymic involution in viable motheaten (me(v)) mice is associated with a loss of intrathymic precursor activity. Dev Immunol. 1992; 2(3):191-205.
    View in: PubMed
    Score: 0.025
  130. Rajan TV, Shultz LD, Greiner DL. Lack of peripherally induced tolerance to established skin allografts in immunologically reconstituted scid mice. Dev Immunol. 1992; 3(1):45-50.
    View in: PubMed
    Score: 0.025
  131. Diiorio P, Jurczyk A, Yang C, Racki WJ, Brehm MA, Atkinson MA, Powers AC, Shultz LD, Greiner DL, Bortell R. Hyperglycemia-induced proliferation of adult human beta cells engrafted into spontaneously diabetic immunodeficient NOD-Rag1null IL2r?null Ins2Akita mice. Pancreas. 2011 Oct; 40(7):1147-9.
    View in: PubMed
    Score: 0.025
  132. Schleifman EB, Bindra R, Leif J, del Campo J, Rogers FA, Uchil P, Kutsch O, Shultz LD, Kumar P, Greiner DL, Glazer PM. Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chem Biol. 2011 Sep 23; 18(9):1189-98.
    View in: PubMed
    Score: 0.025
  133. Greiner DL, Shultz LD, Rossini AA, Mordes JP, Handler ES, Rajan TV. Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras. J Clin Invest. 1991 Aug; 88(2):717-9.
    View in: PubMed
    Score: 0.024
  134. Dorrell C, Grompe MT, Pan FC, Zhong Y, Canaday PS, Shultz LD, Greiner DL, Wright CV, Streeter PR, Grompe M. Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers. Mol Cell Endocrinol. 2011 Jun 06; 339(1-2):144-50.
    View in: PubMed
    Score: 0.024
  135. Libby SJ, Brehm MA, Greiner DL, Shultz LD, McClelland M, Smith KD, Cookson BT, Karlinsey JE, Kinkel TL, Porwollik S, Canals R, Cummings LA, Fang FC. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15589-94.
    View in: PubMed
    Score: 0.023
  136. Subramanya S, Kim SS, Abraham S, Yao J, Kumar M, Kumar P, Haridas V, Lee SK, Shultz LD, Greiner D, N M, Shankar P. Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production. J Virol. 2010 Mar; 84(5):2490-501.
    View in: PubMed
    Score: 0.022
  137. Jaiswal S, Pearson T, Friberg H, Shultz LD, Greiner DL, Rothman AL, Mathew A. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice. PLoS One. 2009 Oct 05; 4(10):e7251.
    View in: PubMed
    Score: 0.021
  138. Chopra P, Diiorio P, Pino SC, Wilson SB, Phillips NE, Mordes JP, Rossini AA, Greiner DL, Shultz LD, Bortell R. Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. In Vivo. 2009 Mar-Apr; 23(2):195-201.
    View in: PubMed
    Score: 0.021
  139. Schmidt MR, Appel MC, Giassi LJ, Greiner DL, Shultz LD, Woodland RT. Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice. PLoS One. 2008 Sep 11; 3(9):e3192.
    View in: PubMed
    Score: 0.020
  140. Kumar P, Ban HS, Kim SS, Wu H, Pearson T, Greiner DL, Laouar A, Yao J, Haridas V, Habiro K, Yang YG, Jeong JH, Lee KY, Kim YH, Kim SW, Peipp M, Fey GH, Manjunath N, Shultz LD, Lee SK, Shankar P. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell. 2008 Aug 22; 134(4):577-86.
    View in: PubMed
    Score: 0.020
  141. Dash Y, Ramesh M, Greiner D, Shultz LD, Klei TR, Rajan TV. Determinants of memory in experimental filarial infections in mice. Parasite Immunol. 2007 Nov; 29(11):567-74.
    View in: PubMed
    Score: 0.019
  142. Medlock ES, Goldschneider I, Greiner DL, Shultz L. Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro. J Immunol. 1987 Jun 01; 138(11):3590-7.
    View in: PubMed
    Score: 0.018
  143. Masaki H, Appel MC, Leahy L, Leif J, Paquin L, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice. Xenotransplantation. 2006 May; 13(3):224-32.
    View in: PubMed
    Score: 0.017
  144. Jaeschke A, Rinc?n M, Doran B, Reilly J, Neuberg D, Greiner DL, Shultz LD, Rossini AA, Flavell RA, Davis RJ. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6931-5.
    View in: PubMed
    Score: 0.016
  145. Gordon EJ, Wicker LS, Peterson LB, Serreze DV, Markees TG, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. Diabetes. 2005 Jan; 54(1):107-15.
    View in: PubMed
    Score: 0.015
  146. Markees TG, Pearson T, Cuthbert A, Pearson AL, Shultz LD, Leif J, Phillips NE, Mordes JP, Greiner DL, Rossini AA. Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody. Transplantation. 2004 Dec 15; 78(11):1601-8.
    View in: PubMed
    Score: 0.015
  147. Banuelos SJ, Shultz LD, Greiner DL, Burzenski LM, Gott B, Lyons BL, Rossini AA, Appel MC. Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. Clin Immunol. 2004 Sep; 112(3):273-83.
    View in: PubMed
    Score: 0.015
  148. Appel MC, Banuelos SJ, Greiner DL, Shultz LD, Mordes JP, Rossini AA. Prolonged survival of neonatal porcine islet xenografts in mice treated with a donor-specific transfusion and anti-CD154 antibody. Transplantation. 2004 May 15; 77(9):1341-9.
    View in: PubMed
    Score: 0.015
  149. Turgeon NA, Banuelos SJ, Shultz LD, Lyons BL, Iwakoshi N, Greiner DL, Mordes JP, Rossini AA, Appel MC. Alloimmune injury and rejection of human skin grafts on human peripheral blood lymphocyte-reconstituted non-obese diabetic severe combined immunodeficient beta2-microglobulin-null mice. Exp Biol Med (Maywood). 2003 Oct; 228(9):1096-104.
    View in: PubMed
    Score: 0.014
  150. Ballen KK, Valinski H, Greiner D, Shultz LD, Becker PS, Hsieh CC, Stewart FM, Quesenberry PJ. Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non-obese diabetic--severe combined immunodeficient assay. Br J Haematol. 2001 Jul; 114(1):211-8.
    View in: PubMed
    Score: 0.012
  151. Gordon EJ, Woda BA, Shultz LD, Rossini AA, Greiner DL, Mordes JP. Rat xenograft survival in mice treated with donor-specific transfusion and anti-CD154 antibody is enhanced by elimination of host CD4+ cells. Transplantation. 2001 Jan 27; 71(2):319-27.
    View in: PubMed
    Score: 0.012
  152. Kollet O, Peled A, Byk T, Ben-Hur H, Greiner D, Shultz L, Lapidot T. beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function. Blood. 2000 May 15; 95(10):3102-5.
    View in: PubMed
    Score: 0.011
  153. Ballen K, Becker PS, Greiner D, Valinski H, Shearin D, Berrios V, Dooner G, Hsieh CC, Wuu J, Shultz L, Cerny J, Leif J, Stewart FM, Quesenberry P. Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice. Br J Haematol. 2000 Mar; 108(3):629-40.
    View in: PubMed
    Score: 0.011
  154. Markees TG, Serreze DV, Phillips NE, Sorli CH, Gordon EJ, Shultz LD, Noelle RJ, Woda BA, Greiner DL, Mordes JP, Rossini AA. NOD mice have a generalized defect in their response to transplantation tolerance induction. Diabetes. 1999 May; 48(5):967-74.
    View in: PubMed
    Score: 0.010
  155. Markees TG, Phillips NE, Gordon EJ, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. J Clin Invest. 1998 Jun 01; 101(11):2446-55.
    View in: PubMed
    Score: 0.010
  156. Rajan TV, Shultz LD, Babu S, Doukas J, Greiner D, Porte P. Diethylcarbamazine (DEC) does not induce nitric oxide (NO) synthesis. Exp Parasitol. 1998 Mar; 88(3):217-22.
    View in: PubMed
    Score: 0.010
  157. Markees TG, Phillips NE, Noelle RJ, Shultz LD, Mordes JP, Greiner DL, Rossini AA. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation. 1997 Jul 27; 64(2):329-35.
    View in: PubMed
    Score: 0.009
  158. Lowry PA, Shultz LD, Greiner DL, Hesselton RM, Kittler EL, Tiarks CY, Rao SS, Reilly J, Leif JH, Ramshaw H, Stewart FM, Quesenberry PJ. Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. Biol Blood Marrow Transplant. 1996 Feb; 2(1):15-23.
    View in: PubMed
    Score: 0.008
  159. Rajan TV, Bailis JM, Yates JA, Shultz LD, Greiner DL, Nelson FK. Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis. Acta Trop. 1994 Dec; 58(3-4):283-9.
    View in: PubMed
    Score: 0.008
  160. Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
    View in: PubMed
    Score: 0.007
  161. Nelson FK, Greiner DL, Shultz LD, Rajan TV. The immunodeficient scid mouse as a model for human lymphatic filariasis. J Exp Med. 1991 Mar 01; 173(3):659-63.
    View in: PubMed
    Score: 0.006
  162. Komschlies KL, Greiner DL, Shultz L, Goldschneider I. Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer. J Exp Med. 1987 Oct 01; 166(4):1162-7.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.