George Witman to Animals
This is a "connection" page, showing publications George Witman has written about Animals.
Connection Strength
0.872
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Hou Y, Witman GB. The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16. Mol Biol Cell. 2017 Sep 01; 28(18):2420-2433.
Score: 0.040
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San Agustin JT, Pazour GJ, Witman GB. Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm. Mol Biol Cell. 2015 Dec 01; 26(24):4358-72.
Score: 0.036
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Schmidts M, Hou Y, Cort?s CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza JM, van Beersum SE, Yap ZM, Letteboer SJ, Taylor SP, Herridge W, Johnson CA, Scambler PJ, Ueffing M, Kayserili H, Krakow D, King SM, Beales PL, Al-Gazali L, Wicking C, Cormier-Daire V, Roepman R, Mitchison HM, Witman GB. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nat Commun. 2015 Jun 05; 6:7074.
Score: 0.035
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Craige B, Witman GB. Flipping a phosphate switch on kinesin-II to turn IFT around. Dev Cell. 2014 Sep 08; 30(5):492-3.
Score: 0.033
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Craige B, Tsao CC, Diener DR, Hou Y, Lechtreck KF, Rosenbaum JL, Witman GB. CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. J Cell Biol. 2010 Sep 06; 190(5):927-40.
Score: 0.025
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Lechtreck KF, Sanderson MJ, Witman GB. High-speed digital imaging of ependymal cilia in the murine brain. Methods Cell Biol. 2009; 91:255-64.
Score: 0.024
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Lechtreck KF, Luro S, Awata J, Witman GB. HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B. Cell Motil Cytoskeleton. 2009 Aug; 66(8):469-82.
Score: 0.023
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Lechtreck KF, Delmotte P, Robinson ML, Sanderson MJ, Witman GB. Mutations in Hydin impair ciliary motility in mice. J Cell Biol. 2008 Feb 11; 180(3):633-43.
Score: 0.021
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Hou Y, Qin H, Follit JA, Pazour GJ, Rosenbaum JL, Witman GB. Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol. 2007 Feb 26; 176(5):653-65.
Score: 0.020
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Lechtreck KF, Witman GB. Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility. J Cell Biol. 2007 Feb 12; 176(4):473-82.
Score: 0.020
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Yang P, Diener DR, Yang C, Kohno T, Pazour GJ, Dienes JM, Agrin NS, King SM, Sale WS, Kamiya R, Rosenbaum JL, Witman GB. Radial spoke proteins of Chlamydomonas flagella. J Cell Sci. 2006 Mar 15; 119(Pt 6):1165-74.
Score: 0.018
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Pazour GJ, Agrin N, Leszyk J, Witman GB. Proteomic analysis of a eukaryotic cilium. J Cell Biol. 2005 Jul 04; 170(1):103-13.
Score: 0.017
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Pazour GJ, Agrin N, Walker BL, Witman GB. Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes. J Med Genet. 2006 Jan; 43(1):62-73.
Score: 0.017
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Hou Y, Pazour GJ, Witman GB. A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport. Mol Biol Cell. 2004 Oct; 15(10):4382-94.
Score: 0.016
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Wirschell M, Pazour G, Yoda A, Hirono M, Kamiya R, Witman GB. Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase. Mol Biol Cell. 2004 Jun; 15(6):2729-41.
Score: 0.016
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Witman GB. Cell motility: deaf Drosophila keep the beat. Curr Biol. 2003 Oct 14; 13(20):R796-8.
Score: 0.016
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Casey DM, Yagi T, Kamiya R, Witman GB. DC3, the smallest subunit of the Chlamydomonas flagellar outer dynein arm-docking complex, is a redox-sensitive calcium-binding protein. J Biol Chem. 2003 Oct 24; 278(43):42652-9.
Score: 0.015
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Casey DM, Inaba K, Pazour GJ, Takada S, Wakabayashi K, Wilkerson CG, Kamiya R, Witman GB. DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC. Mol Biol Cell. 2003 Sep; 14(9):3650-63.
Score: 0.015
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Pazour GJ, Witman GB. The vertebrate primary cilium is a sensory organelle. Curr Opin Cell Biol. 2003 Feb; 15(1):105-10.
Score: 0.015
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Rosenbaum JL, Witman GB. Intraflagellar transport. Nat Rev Mol Cell Biol. 2002 Nov; 3(11):813-25.
Score: 0.015
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Pazour GJ, San Agustin JT, Follit JA, Rosenbaum JL, Witman GB. Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease. Curr Biol. 2002 Jun 04; 12(11):R378-80.
Score: 0.014
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Takada S, Wilkerson CG, Wakabayashi K, Kamiya R, Witman GB. The outer dynein arm-docking complex: composition and characterization of a subunit (oda1) necessary for outer arm assembly. Mol Biol Cell. 2002 Mar; 13(3):1015-29.
Score: 0.014
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Braschi B, Omran H, Witman GB, Pazour GJ, Pfister KK, Bruford EA, King SM. Consensus nomenclature for dyneins and associated assembly factors. J Cell Biol. 2022 02 07; 221(2).
Score: 0.014
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San Agustin JT, Witman GB. Differential expression of the C(s) and Calpha1 isoforms of the catalytic subunit of cyclic 3',5'-adenosine monophosphate-dependent protein kinase testicular cells. Biol Reprod. 2001 Jul; 65(1):151-64.
Score: 0.013
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Pazour GJ, Witman GB. Forward and reverse genetic analysis of microtubule motors in Chlamydomonas. Methods. 2000 Dec; 22(4):285-98.
Score: 0.013
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Agustin JT, Wilkerson CG, Witman GB. The unique catalytic subunit of sperm cAMP-dependent protein kinase is the product of an alternative Calpha mRNA expressed specifically in spermatogenic cells. Mol Biol Cell. 2000 Sep; 11(9):3031-44.
Score: 0.013
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Horst CJ, Fishkind DJ, Pazour GJ, Witman GB. An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning. Cell Motil Cytoskeleton. 1999 Oct; 44(2):143-54.
Score: 0.012
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Pazour GJ, Koutoulis A, Benashski SE, Dickert BL, Sheng H, Patel-King RS, King SM, Witman GB. LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly. Mol Biol Cell. 1999 Oct; 10(10):3507-20.
Score: 0.012
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Pazour GJ, Dickert BL, Witman GB. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J Cell Biol. 1999 Feb 08; 144(3):473-81.
Score: 0.011
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Omoto CK, Gibbons IR, Kamiya R, Shingyoji C, Takahashi K, Witman GB. Rotation of the central pair microtubules in eukaryotic flagella. Mol Biol Cell. 1999 Jan; 10(1):1-4.
Score: 0.011
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San Agustin JT, Leszyk JD, Nuwaysir LM, Witman GB. The catalytic subunit of the cAMP-dependent protein kinase of ovine sperm flagella has a unique amino-terminal sequence. J Biol Chem. 1998 Sep 18; 273(38):24874-83.
Score: 0.011
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Pazour GJ, Wilkerson CG, Witman GB. A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J Cell Biol. 1998 May 18; 141(4):979-92.
Score: 0.011
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Kubo T, Hou Y, Cochran DA, Witman GB, Oda T. A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1). Mol Biol Cell. 2018 05 01; 29(9):1060-1074.
Score: 0.011
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Koutoulis A, Pazour GJ, Wilkerson CG, Inaba K, Sheng H, Takada S, Witman GB. The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex. J Cell Biol. 1997 Jun 02; 137(5):1069-80.
Score: 0.010
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Nakamura K, Wilkerson CG, Witman GB. Functional interaction between Chlamydomonas outer arm dynein subunits: the gamma subunit suppresses the ATPase activity of the alpha beta dimer. Cell Motil Cytoskeleton. 1997; 37(4):338-45.
Score: 0.010
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King SM, Patel-King RS, Wilkerson CG, Witman GB. The 78,000-M(r) intermediate chain of Chlamydomonas outer arm dynein is a microtubule-binding protein. J Cell Biol. 1995 Oct; 131(2):399-409.
Score: 0.009
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Pazour GJ, Sineshchekov OA, Witman GB. Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii. J Cell Biol. 1995 Oct; 131(2):427-40.
Score: 0.009
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McKenzie CW, Craige B, Kroeger TV, Finn R, Wyatt TA, Sisson JH, Pavlik JA, Strittmatter L, Hendricks GM, Witman GB, Lee L. CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice. Mol Biol Cell. 2015 Sep 15; 26(18):3140-9.
Score: 0.009
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Ogawa K, Kamiya R, Wilkerson CG, Witman GB. Interspecies conservation of outer arm dynein intermediate chain sequences defines two intermediate chain subclasses. Mol Biol Cell. 1995 Jun; 6(6):685-96.
Score: 0.009
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Damerla RR, Cui C, Gabriel GC, Liu X, Craige B, Gibbs BC, Francis R, Li Y, Chatterjee B, San Agustin JT, Eguether T, Subramanian R, Witman GB, Michaud JL, Pazour GJ, Lo CW. Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies. Hum Mol Genet. 2015 Jul 15; 24(14):3994-4005.
Score: 0.009
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Wilkerson CG, King SM, Koutoulis A, Pazour GJ, Witman GB. The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly. J Cell Biol. 1995 Apr; 129(1):169-78.
Score: 0.009
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San Agustin JT, Witman GB. Detection of flagellar protein kinases on polyvinylidene difluoride membranes following sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Methods Cell Biol. 1995; 47:135-40.
Score: 0.008
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Horst CJ, Witman GB. Reactivation of Chlamydomonas cell models. Methods Cell Biol. 1995; 47:207-10.
Score: 0.008
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San Agustin JT, Witman GB. Preparation and reactivation of demembranated, cytosol-free ram spermatozoa. Methods Cell Biol. 1995; 47:251-5.
Score: 0.008
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Moss AG, Pazour GJ, Witman GB. Assay of Chlamydomonas phototaxis. Methods Cell Biol. 1995; 47:281-7.
Score: 0.008
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San Agustin JT, Witman GB. Isolation of ram sperm flagella. Methods Cell Biol. 1995; 47:31-6.
Score: 0.008
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Wilkerson CG, King SM, Witman GB. Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein. J Cell Sci. 1994 Mar; 107 ( Pt 3):497-506.
Score: 0.008
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King SM, Witman GB. Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein. J Biol Chem. 1994 Feb 18; 269(7):5452-7.
Score: 0.008
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San Agustin JT, Witman GB. Role of cAMP in the reactivation of demembranated ram spermatozoa. Cell Motil Cytoskeleton. 1994; 27(3):206-18.
Score: 0.008
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Horst CJ, Witman GB. ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance. J Cell Biol. 1993 Feb; 120(3):733-41.
Score: 0.007
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San Agustin JT, Witman GB. Reactivation of demembranated, cytosol-free ram spermatozoa. Cell Motil Cytoskeleton. 1993; 24(4):264-73.
Score: 0.007
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Moss AG, Gatti JL, Witman GB. The motile beta/IC1 subunit of sea urchin sperm outer arm dynein does not form a rigor bond. J Cell Biol. 1992 Sep; 118(5):1177-88.
Score: 0.007
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Moss AG, Sale WS, Fox LA, Witman GB. The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules. J Cell Biol. 1992 Sep; 118(5):1189-200.
Score: 0.007
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Witman GB. Axonemal dyneins. Curr Opin Cell Biol. 1992 Feb; 4(1):74-9.
Score: 0.007
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Yang Y, Cochran DA, Gargano MD, King I, Samhat NK, Burger BP, Sabourin KR, Hou Y, Awata J, Parry DA, Marshall WF, Witman GB, Lu X. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol Biol Cell. 2011 Apr; 22(7):976-87.
Score: 0.006
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Moss AG, Gatti JL, King SM, Witman GB. Purification and characterization of Salmo gairdneri outer arm dynein. Methods Enzymol. 1991; 196:201-22.
Score: 0.006
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King SM, Gatti JL, Moss AG, Witman GB. Outer-arm dynein from trout spermatozoa: substructural organization. Cell Motil Cytoskeleton. 1990; 16(4):266-78.
Score: 0.006
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Engel BD, Lechtreck KF, Sakai T, Ikebe M, Witman GB, Marshall WF. Total internal reflection fluorescence (TIRF) microscopy of Chlamydomonas flagella. Methods Cell Biol. 2009; 93:157-77.
Score: 0.006
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Gatti JL, King SM, Moss AG, Witman GB. Outer arm dynein from trout spermatozoa. Purification, polypeptide composition, and enzymatic properties. J Biol Chem. 1989 Jul 05; 264(19):11450-7.
Score: 0.006
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Wirschell M, Yang C, Yang P, Fox L, Yanagisawa HA, Kamiya R, Witman GB, Porter ME, Sale WS. IC97 is a novel intermediate chain of I1 dynein that interacts with tubulin and regulates interdoublet sliding. Mol Biol Cell. 2009 Jul; 20(13):3044-54.
Score: 0.006
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Paschal BM, King SM, Moss AG, Collins CA, Vallee RB, Witman GB. Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature. 1987 Dec 17-23; 330(6149):672-4.
Score: 0.005
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Huang K, Diener DR, Mitchell A, Pazour GJ, Witman GB, Rosenbaum JL. Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella. J Cell Biol. 2007 Nov 05; 179(3):501-14.
Score: 0.005
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Merchant SS, Prochnik SE, Vallon O, Harris EH, Karpowicz SJ, Witman GB, Terry A, Salamov A, Fritz-Laylin LK, Mar?chal-Drouard L, Marshall WF, Qu LH, Nelson DR, Sanderfoot AA, Spalding MH, Kapitonov VV, Ren Q, Ferris P, Lindquist E, Shapiro H, Lucas SM, Grimwood J, Schmutz J, Cardol P, Cerutti H, Chanfreau G, Chen CL, Cognat V, Croft MT, Dent R, Dutcher S, Fern?ndez E, Fukuzawa H, Gonz?lez-Ballester D, Gonz?lez-Halphen D, Hallmann A, Hanikenne M, Hippler M, Inwood W, Jabbari K, Kalanon M, Kuras R, Lefebvre PA, Lemaire SD, Lobanov AV, Lohr M, Manuell A, Meier I, Mets L, Mittag M, Mittelmeier T, Moroney JV, Moseley J, Napoli C, Nedelcu AM, Niyogi K, Novoselov SV, Paulsen IT, Pazour G, Purton S, Ral JP, Ria?o-Pach?n DM, Riekhof W, Rymarquis L, Schroda M, Stern D, Umen J, Willows R, Wilson N, Zimmer SL, Allmer J, Balk J, Bisova K, Chen CJ, Elias M, Gendler K, Hauser C, Lamb MR, Ledford H, Long JC, Minagawa J, Page MD, Pan J, Pootakham W, Roje S, Rose A, Stahlberg E, Terauchi AM, Yang P, Ball S, Bowler C, Dieckmann CL, Gladyshev VN, Green P, Jorgensen R, Mayfield S, Mueller-Roeber B, Rajamani S, Sayre RT, Brokstein P, Dubchak I, Goodstein D, Hornick L, Huang YW, Jhaveri J, Luo Y, Mart?nez D, Ngau WC, Otillar B, Poliakov A, Porter A, Szajkowski L, Werner G, Zhou K, Grigoriev IV, Rokhsar DS, Grossman AR. The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science. 2007 Oct 12; 318(5848):245-50.
Score: 0.005
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Otter T, King SM, Witman GB. A two-step procedure for efficient electrotransfer of both high-molecular-weight (greater than 400,000) and low-molecular-weight (less than 20,000) proteins. Anal Biochem. 1987 May 01; 162(2):370-7.
Score: 0.005
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Ishijima S, Witman GB. Flagellar movement of intact and demembranated, reactivated ram spermatozoa. Cell Motil Cytoskeleton. 1987; 8(4):375-91.
Score: 0.005
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Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB. Cytoplasmic dynein nomenclature. J Cell Biol. 2005 Nov 07; 171(3):411-3.
Score: 0.004
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DiBella LM, Gorbatyuk O, Sakato M, Wakabayashi K, Patel-King RS, Pazour GJ, Witman GB, King SM. Differential light chain assembly influences outer arm dynein motor function. Mol Biol Cell. 2005 Dec; 16(12):5661-74.
Score: 0.004
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King SM, Otter T, Witman GB. Characterization of monoclonal antibodies against Chlamydomonas flagellar dyneins by high-resolution protein blotting. Proc Natl Acad Sci U S A. 1985 Jul; 82(14):4717-21.
Score: 0.004
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Wang H, San Agustin JT, Witman GB, Kilpatrick DL. Novel role for a sterol response element binding protein in directing spermatogenic cell-specific gene expression. Mol Cell Biol. 2004 Dec; 24(24):10681-8.
Score: 0.004
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Jurczyk A, Gromley A, Redick S, San Agustin J, Witman G, Pazour GJ, Peters DJ, Doxsey S. Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. J Cell Biol. 2004 Aug 30; 166(5):637-43.
Score: 0.004
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Wang S, Luo Y, Wilson PD, Witman GB, Zhou J. The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area. J Am Soc Nephrol. 2004 Mar; 15(3):592-602.
Score: 0.004
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Pazour GJ, Baker SA, Deane JA, Cole DG, Dickert BL, Rosenbaum JL, Witman GB, Besharse JC. The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. J Cell Biol. 2002 Apr 01; 157(1):103-13.
Score: 0.003
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Wakabayashi K, Takada S, Witman GB, Kamiya R. Transport and arrangement of the outer-dynein-arm docking complex in the flagella of Chlamydomonas mutants that lack outer dynein arms. Cell Motil Cytoskeleton. 2001 Apr; 48(4):277-86.
Score: 0.003
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Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, Witman GB, Cole DG. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol. 2000 Oct 30; 151(3):709-18.
Score: 0.003
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Penningroth SM, Witman GB. Effects of adenylyl imidodiphosphate, a nonhydrolyzable adenosine triphosphate analog, on reactivated and rigor wave sea urchin sperm. J Cell Biol. 1978 Dec; 79(3):827-32.
Score: 0.003
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Sakakibara H, Takada S, King SM, Witman GB, Kamiya R. A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain. J Cell Biol. 1993 Aug; 122(3):653-61.
Score: 0.002
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Dentler WL, Granett S, Witman GB, Rosenbaum JL. Directionality of brain microtubule assembly in vitro. Proc Natl Acad Sci U S A. 1974 May; 71(5):1710-4.
Score: 0.001
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Olmsted JB, Witman GB, Carlson K, Rosenbaum JL. Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella. Proc Natl Acad Sci U S A. 1971 Sep; 68(9):2273-7.
Score: 0.000