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Connection

George Witman to Dyneins

This is a "connection" page, showing publications George Witman has written about Dyneins.
Connection Strength

7.033
  1. Hou Y, Witman GB. The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16. Mol Biol Cell. 2017 Sep 01; 28(18):2420-2433.
    View in: PubMed
    Score: 0.537
  2. Schmidts M, Hou Y, Cort?s CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza JM, van Beersum SE, Yap ZM, Letteboer SJ, Taylor SP, Herridge W, Johnson CA, Scambler PJ, Ueffing M, Kayserili H, Krakow D, King SM, Beales PL, Al-Gazali L, Wicking C, Cormier-Daire V, Roepman R, Mitchison HM, Witman GB. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nat Commun. 2015 Jun 05; 6:7074.
    View in: PubMed
    Score: 0.464
  3. Hou Y, Witman GB. Dynein and intraflagellar transport. Exp Cell Res. 2015 May 15; 334(1):26-34.
    View in: PubMed
    Score: 0.455
  4. Hou Y, Qin H, Follit JA, Pazour GJ, Rosenbaum JL, Witman GB. Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J Cell Biol. 2007 Feb 26; 176(5):653-65.
    View in: PubMed
    Score: 0.261
  5. Pazour GJ, Agrin N, Walker BL, Witman GB. Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes. J Med Genet. 2006 Jan; 43(1):62-73.
    View in: PubMed
    Score: 0.232
  6. Hou Y, Pazour GJ, Witman GB. A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport. Mol Biol Cell. 2004 Oct; 15(10):4382-94.
    View in: PubMed
    Score: 0.218
  7. Wirschell M, Pazour G, Yoda A, Hirono M, Kamiya R, Witman GB. Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase. Mol Biol Cell. 2004 Jun; 15(6):2729-41.
    View in: PubMed
    Score: 0.214
  8. Casey DM, Yagi T, Kamiya R, Witman GB. DC3, the smallest subunit of the Chlamydomonas flagellar outer dynein arm-docking complex, is a redox-sensitive calcium-binding protein. J Biol Chem. 2003 Oct 24; 278(43):42652-9.
    View in: PubMed
    Score: 0.205
  9. Casey DM, Inaba K, Pazour GJ, Takada S, Wakabayashi K, Wilkerson CG, Kamiya R, Witman GB. DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC. Mol Biol Cell. 2003 Sep; 14(9):3650-63.
    View in: PubMed
    Score: 0.203
  10. Takada S, Wilkerson CG, Wakabayashi K, Kamiya R, Witman GB. The outer dynein arm-docking complex: composition and characterization of a subunit (oda1) necessary for outer arm assembly. Mol Biol Cell. 2002 Mar; 13(3):1015-29.
    View in: PubMed
    Score: 0.185
  11. Braschi B, Omran H, Witman GB, Pazour GJ, Pfister KK, Bruford EA, King SM. Consensus nomenclature for dyneins and associated assembly factors. J Cell Biol. 2022 02 07; 221(2).
    View in: PubMed
    Score: 0.183
  12. Pazour GJ, Koutoulis A, Benashski SE, Dickert BL, Sheng H, Patel-King RS, King SM, Witman GB. LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly. Mol Biol Cell. 1999 Oct; 10(10):3507-20.
    View in: PubMed
    Score: 0.157
  13. Pazour GJ, Dickert BL, Witman GB. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. J Cell Biol. 1999 Feb 08; 144(3):473-81.
    View in: PubMed
    Score: 0.150
  14. Pazour GJ, Wilkerson CG, Witman GB. A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). J Cell Biol. 1998 May 18; 141(4):979-92.
    View in: PubMed
    Score: 0.142
  15. Koutoulis A, Pazour GJ, Wilkerson CG, Inaba K, Sheng H, Takada S, Witman GB. The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex. J Cell Biol. 1997 Jun 02; 137(5):1069-80.
    View in: PubMed
    Score: 0.133
  16. Brown JM, Mosley M, Montes-Berrueta D, Hou Y, Yang F, Scarbrough C, Witman GB, Wirschell M. Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii. PLoS One. 2017; 12(3):e0173842.
    View in: PubMed
    Score: 0.131
  17. Nakamura K, Wilkerson CG, Witman GB. Functional interaction between Chlamydomonas outer arm dynein subunits: the gamma subunit suppresses the ATPase activity of the alpha beta dimer. Cell Motil Cytoskeleton. 1997; 37(4):338-45.
    View in: PubMed
    Score: 0.129
  18. King SM, Patel-King RS, Wilkerson CG, Witman GB. The 78,000-M(r) intermediate chain of Chlamydomonas outer arm dynein is a microtubule-binding protein. J Cell Biol. 1995 Oct; 131(2):399-409.
    View in: PubMed
    Score: 0.119
  19. Ogawa K, Kamiya R, Wilkerson CG, Witman GB. Interspecies conservation of outer arm dynein intermediate chain sequences defines two intermediate chain subclasses. Mol Biol Cell. 1995 Jun; 6(6):685-96.
    View in: PubMed
    Score: 0.116
  20. Wilkerson CG, King SM, Koutoulis A, Pazour GJ, Witman GB. The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly. J Cell Biol. 1995 Apr; 129(1):169-78.
    View in: PubMed
    Score: 0.115
  21. Song K, Awata J, Tritschler D, Bower R, Witman GB, Porter ME, Nicastro D. In situ localization of N and C termini of subunits of the flagellar nexin-dynein regulatory complex (N-DRC) using SNAP tag and cryo-electron tomography. J Biol Chem. 2015 Feb 27; 290(9):5341-53.
    View in: PubMed
    Score: 0.113
  22. Horst CJ, Witman GB. Reactivation of Chlamydomonas cell models. Methods Cell Biol. 1995; 47:207-10.
    View in: PubMed
    Score: 0.113
  23. San Agustin JT, Witman GB. Preparation and reactivation of demembranated, cytosol-free ram spermatozoa. Methods Cell Biol. 1995; 47:251-5.
    View in: PubMed
    Score: 0.113
  24. Owa M, Furuta A, Usukura J, Arisaka F, King SM, Witman GB, Kamiya R, Wakabayashi K. Cooperative binding of the outer arm-docking complex underlies the regular arrangement of outer arm dynein in the axoneme. Proc Natl Acad Sci U S A. 2014 Jul 01; 111(26):9461-6.
    View in: PubMed
    Score: 0.108
  25. Wilkerson CG, King SM, Witman GB. Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein. J Cell Sci. 1994 Mar; 107 ( Pt 3):497-506.
    View in: PubMed
    Score: 0.106
  26. King SM, Witman GB. Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein. J Biol Chem. 1994 Feb 18; 269(7):5452-7.
    View in: PubMed
    Score: 0.106
  27. Horst CJ, Witman GB. ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance. J Cell Biol. 1993 Feb; 120(3):733-41.
    View in: PubMed
    Score: 0.099
  28. Moss AG, Gatti JL, Witman GB. The motile beta/IC1 subunit of sea urchin sperm outer arm dynein does not form a rigor bond. J Cell Biol. 1992 Sep; 118(5):1177-88.
    View in: PubMed
    Score: 0.096
  29. Moss AG, Sale WS, Fox LA, Witman GB. The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules. J Cell Biol. 1992 Sep; 118(5):1189-200.
    View in: PubMed
    Score: 0.096
  30. Witman GB. Axonemal dyneins. Curr Opin Cell Biol. 1992 Feb; 4(1):74-9.
    View in: PubMed
    Score: 0.092
  31. Hom EF, Witman GB, Harris EH, Dutcher SK, Kamiya R, Mitchell DR, Pazour GJ, Porter ME, Sale WS, Wirschell M, Yagi T, King SM. A unified taxonomy for ciliary dyneins. Cytoskeleton (Hoboken). 2011 Oct; 68(10):555-65.
    View in: PubMed
    Score: 0.090
  32. King SM, Wilkerson CG, Witman GB. The Mr 78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with alpha-tubulin in situ. J Biol Chem. 1991 May 05; 266(13):8401-7.
    View in: PubMed
    Score: 0.087
  33. Moss AG, Gatti JL, King SM, Witman GB. Purification and characterization of Salmo gairdneri outer arm dynein. Methods Enzymol. 1991; 196:201-22.
    View in: PubMed
    Score: 0.085
  34. King SM, Witman GB. Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy. J Biol Chem. 1990 Nov 15; 265(32):19807-11.
    View in: PubMed
    Score: 0.085
  35. King SM, Gatti JL, Moss AG, Witman GB. Outer-arm dynein from trout spermatozoa: substructural organization. Cell Motil Cytoskeleton. 1990; 16(4):266-78.
    View in: PubMed
    Score: 0.080
  36. Gatti JL, King SM, Moss AG, Witman GB. Outer arm dynein from trout spermatozoa. Purification, polypeptide composition, and enzymatic properties. J Biol Chem. 1989 Jul 05; 264(19):11450-7.
    View in: PubMed
    Score: 0.077
  37. King SM, Haley BE, Witman GB. Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding sites. J Biol Chem. 1989 Jun 15; 264(17):10210-8.
    View in: PubMed
    Score: 0.077
  38. Wirschell M, Yang C, Yang P, Fox L, Yanagisawa HA, Kamiya R, Witman GB, Porter ME, Sale WS. IC97 is a novel intermediate chain of I1 dynein that interacts with tubulin and regulates interdoublet sliding. Mol Biol Cell. 2009 Jul; 20(13):3044-54.
    View in: PubMed
    Score: 0.076
  39. King SM, Witman GB. Structure of the gamma heavy chain of the outer arm dynein from Chlamydomonas flagella. J Cell Biol. 1988 Nov; 107(5):1799-808.
    View in: PubMed
    Score: 0.073
  40. King SM, Witman GB. Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Location of epitopes and protease-sensitive sites. J Biol Chem. 1988 Jul 05; 263(19):9244-55.
    View in: PubMed
    Score: 0.072
  41. King SM, Witman GB. Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Masses of chains and sites of ultraviolet-induced vanadate-dependent cleavage. J Biol Chem. 1987 Dec 25; 262(36):17596-604.
    View in: PubMed
    Score: 0.069
  42. Paschal BM, King SM, Moss AG, Collins CA, Vallee RB, Witman GB. Isolated flagellar outer arm dynein translocates brain microtubules in vitro. Nature. 1987 Dec 17-23; 330(6149):672-4.
    View in: PubMed
    Score: 0.069
  43. King SM, Otter T, Witman GB. Purification and characterization of Chlamydomonas flagellar dyneins. Methods Enzymol. 1986; 134:291-306.
    View in: PubMed
    Score: 0.060
  44. Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB. Cytoplasmic dynein nomenclature. J Cell Biol. 2005 Nov 07; 171(3):411-3.
    View in: PubMed
    Score: 0.060
  45. Pfister KK, Haley BE, Witman GB. Labeling of Chlamydomonas 18 S dynein polypeptides by 8-azidoadenosine 5'-triphosphate, a photoaffinity analog of ATP. J Biol Chem. 1985 Oct 15; 260(23):12844-50.
    View in: PubMed
    Score: 0.059
  46. DiBella LM, Gorbatyuk O, Sakato M, Wakabayashi K, Patel-King RS, Pazour GJ, Witman GB, King SM. Differential light chain assembly influences outer arm dynein motor function. Mol Biol Cell. 2005 Dec; 16(12):5661-74.
    View in: PubMed
    Score: 0.059
  47. King SM, Otter T, Witman GB. Characterization of monoclonal antibodies against Chlamydomonas flagellar dyneins by high-resolution protein blotting. Proc Natl Acad Sci U S A. 1985 Jul; 82(14):4717-21.
    View in: PubMed
    Score: 0.058
  48. Pfister KK, Witman GB. Subfractionation of Chlamydomonas 18 S dynein into two unique subunits containing ATPase activity. J Biol Chem. 1984 Oct 10; 259(19):12072-80.
    View in: PubMed
    Score: 0.055
  49. Pfister KK, Haley BE, Witman GB. The photoaffinity probe 8-azidoadenosine 5'-triphosphate selectively labels the heavy chain of Chlamydomonas 12 S dynein. J Biol Chem. 1984 Jul 10; 259(13):8499-504.
    View in: PubMed
    Score: 0.054
  50. Pfister KK, Fay RB, Witman GB. Purification and polypeptide composition of dynein ATPases from Chlamydomonas flagella. Cell Motil. 1982; 2(6):525-47.
    View in: PubMed
    Score: 0.046
  51. Witman GB, Minervini N. Dynein arm conformation and mechanochemical transduction in the eukaryotic flagellum. Symp Soc Exp Biol. 1982; 35:203-23.
    View in: PubMed
    Score: 0.046
  52. Wakabayashi K, Takada S, Witman GB, Kamiya R. Transport and arrangement of the outer-dynein-arm docking complex in the flagella of Chlamydomonas mutants that lack outer dynein arms. Cell Motil Cytoskeleton. 2001 Apr; 48(4):277-86.
    View in: PubMed
    Score: 0.043
  53. Pazour GJ, Witman GB. Forward and reverse genetic analysis of microtubule motors in Chlamydomonas. Methods. 2000 Dec; 22(4):285-98.
    View in: PubMed
    Score: 0.042
  54. Kubo T, Hou Y, Cochran DA, Witman GB, Oda T. A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1). Mol Biol Cell. 2018 05 01; 29(9):1060-1074.
    View in: PubMed
    Score: 0.035
  55. Sakakibara H, Takada S, King SM, Witman GB, Kamiya R. A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain. J Cell Biol. 1993 Aug; 122(3):653-61.
    View in: PubMed
    Score: 0.026
  56. Engel BD, Ishikawa H, Wemmer KA, Geimer S, Wakabayashi K, Hirono M, Craige B, Pazour GJ, Witman GB, Kamiya R, Marshall WF. The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function. J Cell Biol. 2012 Oct 01; 199(1):151-67.
    View in: PubMed
    Score: 0.024
  57. Hoops HJ, Witman GB. Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella. J Cell Biol. 1983 Sep; 97(3):902-8.
    View in: PubMed
    Score: 0.013
  58. Bessen M, Fay RB, Witman GB. Calcium control of waveform in isolated flagellar axonemes of Chlamydomonas. J Cell Biol. 1980 Aug; 86(2):446-55.
    View in: PubMed
    Score: 0.010
  59. Penningroth SM, Witman GB. Effects of adenylyl imidodiphosphate, a nonhydrolyzable adenosine triphosphate analog, on reactivated and rigor wave sea urchin sperm. J Cell Biol. 1978 Dec; 79(3):827-32.
    View in: PubMed
    Score: 0.009
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.