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Connection

Job Dekker to Chromosomes

This is a "connection" page, showing publications Job Dekker has written about Chromosomes.
Connection Strength

13.253
  1. Schooley A, Venev SV, Aksenova V, Lehman JW, Navarrete E, Pai AA, Dasso M, Dekker J. Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm. Nat Cell Biol. 2026 Jan; 28(1):82-97.
    View in: PubMed
    Score: 0.852
  2. Oomen ME, Fox AN, Gonzalez I, Molliex A, Papadopoulou T, Navarro P, Dekker J. Mitotic chromosomes harbor cell type- and species-specific structural features within a universal loop array conformation. Genome Res. 2025 08 01; 35(8):1733-1744.
    View in: PubMed
    Score: 0.829
  3. Dekker J, Mirny LA. The chromosome folding problem and how cells solve it. Cell. 2024 Nov 14; 187(23):6424-6450.
    View in: PubMed
    Score: 0.789
  4. Hildebrand EM, Polovnikov K, Dekker B, Liu Y, Lafontaine DL, Fox AN, Li Y, Venev SV, Mirny LA, Dekker J. Mitotic chromosomes are self-entangled and disentangle through a topoisomerase-II-dependent two-stage exit from mitosis. Mol Cell. 2024 04 18; 84(8):1422-1441.e14.
    View in: PubMed
    Score: 0.755
  5. Mirny L, Dekker J. Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions. Cold Spring Harb Perspect Biol. 2022 07 01; 14(7).
    View in: PubMed
    Score: 0.670
  6. Nand A, Zhan Y, Salazar OR, Aranda M, Voolstra CR, Dekker J. Genetic and spatial organization of the unusual chromosomes of the dinoflagellate Symbiodinium microadriaticum. Nat Genet. 2021 05; 53(5):618-629.
    View in: PubMed
    Score: 0.617
  7. Hildebrand EM, Dekker J. Mechanisms and Functions of Chromosome Compartmentalization. Trends Biochem Sci. 2020 05; 45(5):385-396.
    View in: PubMed
    Score: 0.568
  8. Gibcus JH, Samejima K, Goloborodko A, Samejima I, Naumova N, Nuebler J, Kanemaki MT, Xie L, Paulson JR, Earnshaw WC, Mirny LA, Dekker J. A pathway for mitotic chromosome formation. Science. 2018 02 09; 359(6376).
    View in: PubMed
    Score: 0.492
  9. Oomen ME, Dekker J. Epigenetic characteristics of the mitotic chromosome in 1D and 3D. Crit Rev Biochem Mol Biol. 2017 Apr; 52(2):185-204.
    View in: PubMed
    Score: 0.461
  10. Dekker J. Mapping the 3D genome: Aiming for consilience. Nat Rev Mol Cell Biol. 2016 Nov 21; 17(12):741-742.
    View in: PubMed
    Score: 0.454
  11. Dekker J, Guttman M, Lomvardas S. A Guide to Packing Your DNA. Cell. 2016 Apr 07; 165(2):259-61.
    View in: PubMed
    Score: 0.435
  12. Dekker J, Mirny L. The 3D Genome as Moderator of Chromosomal Communication. Cell. 2016 Mar 10; 164(6):1110-1121.
    View in: PubMed
    Score: 0.432
  13. Belton JM, Dekker J. Randomized ligation control for chromosome conformation capture. Cold Spring Harb Protoc. 2015 Jun 01; 2015(6):587-92.
    View in: PubMed
    Score: 0.410
  14. Belton JM, Dekker J. Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast. Cold Spring Harb Protoc. 2015 Jun 01; 2015(6):593-8.
    View in: PubMed
    Score: 0.410
  15. Dekker J, Mirny L. Biological techniques: Chromosomes captured one by one. Nature. 2013 Oct 03; 502(7469):45-6.
    View in: PubMed
    Score: 0.365
  16. Sanyal A, Ba? D, Mart?-Renom MA, Dekker J. Chromatin globules: a common motif of higher order chromosome structure? Curr Opin Cell Biol. 2011 Jun; 23(3):325-31.
    View in: PubMed
    Score: 0.308
  17. van Steensel B, Dekker J. Genomics tools for unraveling chromosome architecture. Nat Biotechnol. 2010 Oct; 28(10):1089-95.
    View in: PubMed
    Score: 0.297
  18. Miele A, Dekker J. Mapping cis- and trans- chromatin interaction networks using chromosome conformation capture (3C). Methods Mol Biol. 2009; 464:105-21.
    View in: PubMed
    Score: 0.263
  19. Miele A, Dekker J. Long-range chromosomal interactions and gene regulation. Mol Biosyst. 2008 Nov; 4(11):1046-57.
    View in: PubMed
    Score: 0.256
  20. Dekker J. Gene regulation in the third dimension. Science. 2008 Mar 28; 319(5871):1793-4.
    View in: PubMed
    Score: 0.249
  21. Dostie J, Zhan Y, Dekker J. Chromosome conformation capture carbon copy technology. Curr Protoc Mol Biol. 2007 Oct; Chapter 21:Unit 21.14.
    View in: PubMed
    Score: 0.241
  22. Miele A, Gheldof N, Tabuchi TM, Dostie J, Dekker J. Mapping chromatin interactions by chromosome conformation capture. Curr Protoc Mol Biol. 2006 May; Chapter 21:Unit 21.11.
    View in: PubMed
    Score: 0.218
  23. Dekker J. The three 'C' s of chromosome conformation capture: controls, controls, controls. Nat Methods. 2006 Jan; 3(1):17-21.
    View in: PubMed
    Score: 0.213
  24. Samejima K, Gibcus JH, Abraham S, Cisneros-Soberanis F, Samejima I, Beckett AJ, Pucekov? N, Abad MA, Spanos C, Medina-Pritchard B, Paulson JR, Xie L, Jeyaprakash AA, Prior IA, Mirny LA, Dekker J, Goloborodko A, Earnshaw WC. Rules of engagement for condensins and cohesins guide mitotic chromosome formation. Science. 2025 04 11; 388(6743):eadq1709.
    View in: PubMed
    Score: 0.203
  25. Zhou CY, Dekker B, Liu Z, Cabrera H, Ryan J, Dekker J, Heald R. Mitotic chromosomes scale to nuclear-cytoplasmic ratio and cell size in Xenopus. Elife. 2023 04 25; 12.
    View in: PubMed
    Score: 0.177
  26. Yang L, Akgol Oksuz B, Dekker J, Gibcus JH. Capturing Chromosome Conformation Across Length Scales. J Vis Exp. 2023 01 20; (191).
    View in: PubMed
    Score: 0.174
  27. Sanders JT, Golloshi R, Das P, Xu Y, Terry PH, Nash DG, Dekker J, McCord RP. Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling. Sci Rep. 2022 03 18; 12(1):4721.
    View in: PubMed
    Score: 0.164
  28. Leidescher S, Ribisel J, Ullrich S, Feodorova Y, Hildebrand E, Galitsyna A, Bultmann S, Link S, Thanisch K, Mulholland C, Dekker J, Leonhardt H, Mirny L, Solovei I. Spatial organization of transcribed eukaryotic genes. Nat Cell Biol. 2022 03; 24(3):327-339.
    View in: PubMed
    Score: 0.163
  29. Choppakatla P, Dekker B, Cutts EE, Vannini A, Dekker J, Funabiki H. Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization. Elife. 2021 08 18; 10.
    View in: PubMed
    Score: 0.158
  30. Lafontaine DL, Yang L, Dekker J, Gibcus JH. Hi-C 3.0: Improved Protocol for Genome-Wide Chromosome Conformation Capture. Curr Protoc. 2021 Jul; 1(7):e198.
    View in: PubMed
    Score: 0.156
  31. Fitz-James MH, Tong P, Pidoux AL, Ozadam H, Yang L, White SA, Dekker J, Allshire RC. Large domains of heterochromatin direct the formation of short mitotic chromosome loops. Elife. 2020 09 11; 9.
    View in: PubMed
    Score: 0.148
  32. Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S. The 4D nucleome project. Nature. 2017 09 13; 549(7671):219-226.
    View in: PubMed
    Score: 0.120
  33. Belaghzal H, Dekker J, Gibcus JH. Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation. Methods. 2017 07 01; 123:56-65.
    View in: PubMed
    Score: 0.117
  34. Servant N, Varoquaux N, Lajoie BR, Viara E, Chen CJ, Vert JP, Heard E, Dekker J, Barillot E. HiC-Pro: an optimized and flexible pipeline for Hi-C data processing. Genome Biol. 2015 Dec 01; 16:259.
    View in: PubMed
    Score: 0.106
  35. Dekker J, Misteli T. Long-Range Chromatin Interactions. Cold Spring Harb Perspect Biol. 2015 Oct 01; 7(10):a019356.
    View in: PubMed
    Score: 0.105
  36. Belton JM, Dekker J. Chromosome Conformation Capture (3C) in Budding Yeast. Cold Spring Harb Protoc. 2015 Jun 01; 2015(6):580-6.
    View in: PubMed
    Score: 0.102
  37. Giorgetti L, Galupa R, Nora EP, Piolot T, Lam F, Dekker J, Tiana G, Heard E. Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription. Cell. 2014 May 08; 157(4):950-63.
    View in: PubMed
    Score: 0.095
  38. Gibcus JH, Dekker J. The hierarchy of the 3D genome. Mol Cell. 2013 Mar 07; 49(5):773-82.
    View in: PubMed
    Score: 0.088
  39. Noble WS, Blau CA, Dekker J, Duan ZJ, Mao Y. The structure and function of chromatin and chromosomes. Pac Symp Biocomput. 2012; 434-40.
    View in: PubMed
    Score: 0.081
  40. Naumova N, Dekker J. Integrating one-dimensional and three-dimensional maps of genomes. J Cell Sci. 2010 Jun 15; 123(Pt 12):1979-88.
    View in: PubMed
    Score: 0.073
  41. van Berkum NL, Lieberman-Aiden E, Williams L, Imakaev M, Gnirke A, Mirny LA, Dekker J, Lander ES. Hi-C: a method to study the three-dimensional architecture of genomes. J Vis Exp. 2010 May 06; (39).
    View in: PubMed
    Score: 0.072
  42. Dekker J. Mapping in vivo chromatin interactions in yeast suggests an extended chromatin fiber with regional variation in compaction. J Biol Chem. 2008 Dec 12; 283(50):34532-40.
    View in: PubMed
    Score: 0.065
  43. Lanzuolo C, Roure V, Dekker J, Bantignies F, Orlando V. Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex. Nat Cell Biol. 2007 Oct; 9(10):1167-74.
    View in: PubMed
    Score: 0.060
  44. Hag?ge H, Klous P, Braem C, Splinter E, Dekker J, Cathala G, de Laat W, Forn? T. Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nat Protoc. 2007; 2(7):1722-33.
    View in: PubMed
    Score: 0.057
  45. Kleckner N, Zickler D, Jones GH, Dekker J, Padmore R, Henle J, Hutchinson J. A mechanical basis for chromosome function. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12592-7.
    View in: PubMed
    Score: 0.048
  46. Stevens L, Moya ND, Tanny RE, Gibson SB, Tracey A, Na H, Chitrakar R, Dekker J, Walhout AJM, Baugh LR, Andersen EC. Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform for Comparative Genomics. Genome Biol Evol. 2022 04 10; 14(4).
    View in: PubMed
    Score: 0.041
  47. Brossas C, Valton AL, Venev SV, Chilaka S, Counillon A, Laurent M, Goncalves C, Duriez B, Picard F, Dekker J, Prioleau MN. Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain. EMBO J. 2020 11 02; 39(21):e99520.
    View in: PubMed
    Score: 0.037
  48. Finn EH, Pegoraro G, Brand?o HB, Valton AL, Oomen ME, Dekker J, Mirny L, Misteli T. Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization. Cell. 2019 03 07; 176(6):1502-1515.e10.
    View in: PubMed
    Score: 0.033
  49. Kind J, Pagie L, de Vries SS, Nahidiazar L, Dey SS, Bienko M, Zhan Y, Lajoie B, de Graaf CA, Amendola M, Fudenberg G, Imakaev M, Mirny LA, Jalink K, Dekker J, van Oudenaarden A, van Steensel B. Genome-wide maps of nuclear lamina interactions in single human cells. Cell. 2015 Sep 24; 163(1):134-47.
    View in: PubMed
    Score: 0.026
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.