Christopher Sassetti to Humans
This is a "connection" page, showing publications Christopher Sassetti has written about Humans.
Connection Strength
0.542
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Koh EI, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A, Zimmerman MD, Aslebagh R, Baker RE, Shaffer SA, Guinn KM, Fitzgerald M, Dartois V, Ehrt S, Hung DT, Ioerger TR, Rubin EJ, Rhee KY, Schnappinger D, Sassetti CM. Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2201632119.
Score: 0.031
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Cai Y, Jaecklein E, Mackenzie JS, Papavinasasundaram K, Olive AJ, Chen X, Steyn AJC, Sassetti CM. Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase. PLoS Pathog. 2021 07; 17(7):e1008911.
Score: 0.029
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Smith CM, Proulx MK, Lai R, Kiritsy MC, Bell TA, Hock P, Pardo-Manuel de Villena F, Ferris MT, Baker RE, Behar SM, Sassetti CM. Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice. mBio. 2019 11 26; 10(6).
Score: 0.026
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Rittershaus ESC, Baek SH, Krieger IV, Nelson SJ, Cheng YS, Nambi S, Baker RE, Leszyk JD, Shaffer SA, Sacchettini JC, Sassetti CM. A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. Cell Chem Biol. 2018 12 20; 25(12):1495-1505.e3.
Score: 0.024
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Olive AJ, Sassetti CM. Tolerating the Unwelcome Guest; How the Host Withstands Persistent Mycobacterium tuberculosis. Front Immunol. 2018; 9:2094.
Score: 0.024
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Smith CM, Sassetti CM. Modeling Diversity: Do Homogeneous Laboratory Strains Limit Discovery? Trends Microbiol. 2018 11; 26(11):892-895.
Score: 0.024
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Olive AJ, Smith CM, Kiritsy MC, Sassetti CM. The Phagocyte Oxidase Controls Tolerance to Mycobacterium tuberculosis Infection. J Immunol. 2018 09 15; 201(6):1705-1716.
Score: 0.024
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Mishra BB, Lovewell RR, Olive AJ, Zhang G, Wang W, Eugenin E, Smith CM, Phuah JY, Long JE, Dubuke ML, Palace SG, Goguen JD, Baker RE, Nambi S, Mishra R, Booty MG, Baer CE, Shaffer SA, Dartois V, McCormick BA, Chen X, Sassetti CM. Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis. Nat Microbiol. 2017 May 15; 2:17072.
Score: 0.022
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Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G, Sassetti CM. Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype. mBio. 2016 09 20; 7(5).
Score: 0.021
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Prigozhin DM, Papavinasasundaram KG, Baer CE, Murphy KC, Moskaleva A, Chen TY, Alber T, Sassetti CM. Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J Biol Chem. 2016 10 28; 291(44):22961-22969.
Score: 0.021
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Olive AJ, Sassetti CM. Metabolic crosstalk between host and pathogen: sensing, adapting and competing. Nat Rev Microbiol. 2016 Apr; 14(4):221-34.
Score: 0.020
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Baer CE, Rubin EJ, Sassetti CM. New insights into TB physiology suggest untapped therapeutic opportunities. Immunol Rev. 2015 Mar; 264(1):327-43.
Score: 0.019
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Olive AJ, Sassetti CM. New TB treatments hiding in plain sight. EMBO Mol Med. 2015 Feb; 7(2):125-6.
Score: 0.019
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Behar SM, Sassetti CM. Immunology: Fixing the odds against tuberculosis. Nature. 2014 Jul 03; 511(7507):39-40.
Score: 0.018
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O'Sullivan BP, Sassetti CM. Infection control in cystic fibrosis: share and share alike. Lancet. 2013 May 04; 381(9877):1517-9.
Score: 0.016
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Mishra BB, Rathinam VA, Martens GW, Martinot AJ, Kornfeld H, Fitzgerald KA, Sassetti CM. Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?. Nat Immunol. 2013 Jan; 14(1):52-60.
Score: 0.016
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Sassetti CM, Rubin EJ. Relics of selection in the mycobacterial genome. Nat Genet. 2010 Jun; 42(6):476-8.
Score: 0.014
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Sassetti CM, Rubin EJ. The open book of infectious diseases. Nat Med. 2007 Mar; 13(3):279-80.
Score: 0.011
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Pullen KM, Finethy R, Ko SB, Reames CJ, Sassetti CM, Lauffenburger DA. Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection. NPJ Syst Biol Appl. 2025 Feb 15; 11(1):19.
Score: 0.009
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Jaecklein E, Papavinasasundaram K, Ostroff GR, Sassetti C, Soto ER. Targeted delivery of antitubercular drugs using glucan lipid particles. Microbiol Spectr. 2025 Mar 04; 13(3):e0274424.
Score: 0.009
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Simwela NV, Johnston L, Bitar PP, Jaecklein E, Altier C, Sassetti CM, Russell DG. Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth. Nat Commun. 2024 Oct 29; 15(1):9322.
Score: 0.009
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Cuthbert BJ, Mendoza J, de Miranda R, Papavinasasundaram K, Sassetti CM, Goulding CW. The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria. Metallomics. 2024 03 12; 16(3).
Score: 0.009
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Kurtz SL, Baker RE, Boehm FJ, Lehman CC, Mittereder LR, Khan H, Rossi AP, Gatti DM, Beamer G, Sassetti CM, Elkins KL. Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice. PLoS Pathog. 2024 Mar; 20(3):e1012069.
Score: 0.009
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de Miranda R, Cuthbert BJ, Klevorn T, Chao A, Mendoza J, Arbing M, Sieminski PJ, Papavinasasundaram K, Abdul-Hafiz S, Chan S, Sassetti CM, Ehrt S, Goulding CW. Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake. PLoS Pathog. 2023 09; 19(9):e1011650.
Score: 0.009
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Martinez N, Smulan LJ, Jameson ML, Smith CM, Cavallo K, Bellerose M, Williams J, West K, Sassetti CM, Singhal A, Kornfeld H. Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes. Nat Commun. 2023 09 20; 14(1):5840.
Score: 0.008
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Lai R, Gong DN, Williams T, Ogunsola AF, Cavallo K, Lindestam Arlehamn CS, Acolatse S, Beamer GL, Ferris MT, Sassetti CM, Lauffenburger DA, Behar SM. Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis. J Clin Invest. 2023 07 03; 133(13).
Score: 0.008
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Wilburn KM, Meade RK, Heckenberg EM, Dockterman J, Coers J, Sassetti CM, Olive AJ, Smith CM. Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice. Infect Immun. 2023 02 16; 91(2):e0051022.
Score: 0.008
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Shah JA, Warr AJ, Graustein AD, Saha A, Dunstan SJ, Thuong NTT, Thwaites GE, Caws M, Thai PVK, Bang ND, Chau TTH, Khor CC, Li Z, Hibberd M, Chang X, Nguyen FK, Hernandez CA, Jones MA, Sassetti CM, Fitzgerald KA, Musvosvi M, Gela A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk. J Immunol. 2022 03 15; 208(6):1352-1361.
Score: 0.008
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Kiritsy MC, McCann K, Mott D, Holland SM, Behar SM, Sassetti CM, Olive AJ. Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells. Elife. 2021 11 02; 10.
Score: 0.007
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Sutiwisesak R, Hicks ND, Boyce S, Murphy KC, Papavinasasundaram K, Carpenter SM, Boucau J, Joshi N, Le Gall S, Fortune SM, Sassetti CM, Behar SM. A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response. PLoS Pathog. 2020 10; 16(10):e1009000.
Score: 0.007
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Sassetti C, Van Zante A, Rosen SD. Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucins. J Biol Chem. 2000 Mar 24; 275(12):9001-10.
Score: 0.007
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Daniel-Wayman S, Abate G, Barber DL, Bermudez LE, Coler RN, Cynamon MH, Daley CL, Davidson RM, Dick T, Floto RA, Henkle E, Holland SM, Jackson M, Lee RE, Nuermberger EL, Olivier KN, Ordway DJ, Prevots DR, Sacchettini JC, Salfinger M, Sassetti CM, Sizemore CF, Winthrop KL, Zelazny AM. Advancing Translational Science for Pulmonary Nontuberculous Mycobacterial Infections. A Road Map for Research. Am J Respir Crit Care Med. 2019 04 15; 199(8):947-951.
Score: 0.006
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Sassetti C, Tangemann K, Singer MS, Kershaw DB, Rosen SD. Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34. J Exp Med. 1998 Jun 15; 187(12):1965-75.
Score: 0.006
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K?ster S, Klevorn T, Papavinasasundaram K, Sassetti CM, Portal-Celhay C, Philips JA. Consequence of enhanced LC3-trafficking for a live, attenuated M. tuberculosis vaccine. Vaccine. 2018 02 08; 36(7):939-944.
Score: 0.006
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Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM. Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection. mBio. 2017 10 24; 8(5).
Score: 0.006
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Cai Y, Yang Q, Liao M, Wang H, Zhang C, Nambi S, Wang W, Zhang M, Wu J, Deng G, Deng Q, Liu H, Zhou B, Jin Q, Feng CG, Sassetti CM, Wang F, Chen X. xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation. Oncotarget. 2016 May 24; 7(21):31001-13.
Score: 0.005
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Lovewell RR, Sassetti CM, VanderVen BC. Chewing the fat: lipid metabolism and homeostasis during M. tuberculosis infection. Curr Opin Microbiol. 2016 Feb; 29:30-6.
Score: 0.005
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Zhang G, Zhou B, Li S, Yue J, Yang H, Wen Y, Zhan S, Wang W, Liao M, Zhang M, Zeng G, Feng CG, Sassetti CM, Chen X. Allele-specific induction of IL-1? expression by C/EBP? and PU.1 contributes to increased tuberculosis susceptibility. PLoS Pathog. 2014 Oct; 10(10):e1004426.
Score: 0.005
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Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. PLoS Pathog. 2013; 9(7):e1003419.
Score: 0.004
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Padilla-Benavides T, Long JE, Raimunda D, Sassetti CM, Arg?ello JM. A novel P(1B)-type Mn2+-transporting ATPase is required for secreted protein metallation in mycobacteria. J Biol Chem. 2013 Apr 19; 288(16):11334-47.
Score: 0.004
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Murry JP, Pandey AK, Sassetti CM, Rubin EJ. Phthiocerol dimycocerosate transport is required for resisting interferon-gamma-independent immunity. J Infect Dis. 2009 Sep 01; 200(5):774-82.
Score: 0.003
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Miner MD, Chang JC, Pandey AK, Sassetti CM, Sherman DR. Role of cholesterol in Mycobacterium tuberculosis infection. Indian J Exp Biol. 2009 Jun; 47(6):407-11.
Score: 0.003
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Fieger CB, Sassetti CM, Rosen SD. Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x. J Biol Chem. 2003 Jul 25; 278(30):27390-8.
Score: 0.002
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Papadopoulos EJ, Sassetti C, Saeki H, Yamada N, Kawamura T, Fitzhugh DJ, Saraf MA, Schall T, Blauvelt A, Rosen SD, Hwang ST. Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. Eur J Immunol. 1999 08; 29(8):2551-9.
Score: 0.002