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Connection

Leslie Shaw to Breast Neoplasms

This is a "connection" page, showing publications Leslie Shaw has written about Breast Neoplasms.
Connection Strength

2.846
  1. Lero MW, Shaw LM. Diversity of insulin and IGF signaling in breast cancer: Implications for therapy. Mol Cell Endocrinol. 2021 05 01; 527:111213.
    View in: PubMed
    Score: 0.392
  2. Mercado-Matos J, Janusis J, Zhu S, Chen SS, Shaw LM. Identification of a Novel Invasion-Promoting Region in Insulin Receptor Substrate 2. Mol Cell Biol. 2018 07 15; 38(14).
    View in: PubMed
    Score: 0.327
  3. Mercado-Matos J, Clark JL, Piper AJ, Janusis J, Shaw LM. Differential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells. J Biol Chem. 2017 05 12; 292(19):7806-7816.
    View in: PubMed
    Score: 0.299
  4. Rohatgi RA, Janusis J, Leonard D, Bellv? KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015 Oct 16; 34(42):5352-62.
    View in: PubMed
    Score: 0.258
  5. Landis J, Shaw LM. Insulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3? to regulate aerobic glycolysis. J Biol Chem. 2014 Jun 27; 289(26):18603-13.
    View in: PubMed
    Score: 0.245
  6. Yang X, Dutta U, Shaw LM. SHP2 mediates the localized activation of Fyn downstream of the a6?4 integrin to promote carcinoma invasion. Mol Cell Biol. 2010 Nov; 30(22):5306-17.
    View in: PubMed
    Score: 0.191
  7. Mardilovich K, Shaw LM. Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion. Cancer Res. 2009 Dec 01; 69(23):8894-901.
    View in: PubMed
    Score: 0.180
  8. Pankratz SL, Tan EY, Fine Y, Mercurio AM, Shaw LM. Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1. J Biol Chem. 2009 Jan 23; 284(4):2031-7.
    View in: PubMed
    Score: 0.168
  9. Gibson SL, Ma Z, Shaw LM. Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis. Cell Cycle. 2007 Mar 15; 6(6):631-7.
    View in: PubMed
    Score: 0.149
  10. Shaw LM. Integrin function in breast carcinoma progression. J Mammary Gland Biol Neoplasia. 1999 Oct; 4(4):367-76.
    View in: PubMed
    Score: 0.089
  11. Zhu S, Ward BM, Yu J, Matthew-Onabanjo AN, Janusis J, Hsieh CC, Tomaszewicz K, Hutchinson L, Zhu LJ, Kandil D, Shaw LM. IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma. JCI Insight. 2018 04 19; 3(8).
    View in: PubMed
    Score: 0.081
  12. Becker MA, Ibrahim YH, Oh AS, Fagan DH, Byron SA, Sarver AL, Lee AV, Shaw LM, Fan C, Perou CM, Yee D. Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer. PLoS One. 2016; 11(3):e0150564.
    View in: PubMed
    Score: 0.070
  13. Shaw LM, Chao C, Wewer UM, Mercurio AM. Function of the integrin alpha 6 beta 1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor. Cancer Res. 1996 Mar 01; 56(5):959-63.
    View in: PubMed
    Score: 0.069
  14. Browne G, Taipaleenm?ki H, Bishop NM, Madasu SC, Shaw LM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion. J Cell Physiol. 2015 Oct; 230(10):2522-32.
    View in: PubMed
    Score: 0.068
  15. Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/a6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med. 2013 Apr; 5(4):488-508.
    View in: PubMed
    Score: 0.056
  16. Dutta U, Shaw LM. A key tyrosine (Y1494) in the beta4 integrin regulates multiple signaling pathways important for tumor development and progression. Cancer Res. 2008 Nov 01; 68(21):8779-87.
    View in: PubMed
    Score: 0.042
  17. Ma Z, Gibson SL, Byrne MA, Zhang J, White MF, Shaw LM. Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis. Mol Cell Biol. 2006 Dec; 26(24):9338-51.
    View in: PubMed
    Score: 0.036
  18. Nagle JA, Ma Z, Byrne MA, White MF, Shaw LM. Involvement of insulin receptor substrate 2 in mammary tumor metastasis. Mol Cell Biol. 2004 Nov; 24(22):9726-35.
    View in: PubMed
    Score: 0.032
  19. Carlisle AE, Lee N, Matthew-Onabanjo AN, Spears ME, Park SJ, Youkana D, Doshi MB, Peppers A, Li R, Joseph AB, Smith M, Simin K, Zhu LJ, Greer PL, Shaw LM, Kim D. Selenium detoxification is required for cancer-cell survival. Nat Metab. 2020 07; 2(7):603-611.
    View in: PubMed
    Score: 0.023
  20. Zrihan-Licht S, Fu Y, Settleman J, Schinkmann K, Shaw L, Keydar I, Avraham S, Avraham H. RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion. Oncogene. 2000 Mar 02; 19(10):1318-28.
    View in: PubMed
    Score: 0.023
  21. Wewer UM, Shaw LM, Albrechtsen R, Mercurio AM. The integrin alpha 6 beta 1 promotes the survival of metastatic human breast carcinoma cells in mice. Am J Pathol. 1997 Nov; 151(5):1191-8.
    View in: PubMed
    Score: 0.020
  22. Goel HL, Gritsko T, Pursell B, Chang C, Shultz LD, Greiner DL, Norum JH, Toftgard R, Shaw LM, Mercurio AM. Regulated splicing of the a6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 2014 May 08; 7(3):747-61.
    View in: PubMed
    Score: 0.015
  23. Chung J, Bachelder RE, Lipscomb EA, Shaw LM, Mercurio AM. Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. J Cell Biol. 2002 Jul 08; 158(1):165-74.
    View in: PubMed
    Score: 0.007
  24. Jauliac S, L?pez-Rodriguez C, Shaw LM, Brown LF, Rao A, Toker A. The role of NFAT transcription factors in integrin-mediated carcinoma invasion. Nat Cell Biol. 2002 Jul; 4(7):540-4.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.