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Connection

Arthur Mercurio to Integrins

This is a "connection" page, showing publications Arthur Mercurio has written about Integrins.
Connection Strength

4.638
  1. Chung J, Bachelder RE, Lipscomb EA, Shaw LM, Mercurio AM. Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. J Cell Biol. 2002 Jul 08; 158(1):165-74.
    View in: PubMed
    Score: 0.189
  2. Rabinovitz I, Gipson IK, Mercurio AM. Traction forces mediated by alpha6beta4 integrin: implications for basement membrane organization and tumor invasion. Mol Biol Cell. 2001 Dec; 12(12):4030-43.
    View in: PubMed
    Score: 0.182
  3. Mercurio AM, Rabinovitz I, Shaw LM. The alpha 6 beta 4 integrin and epithelial cell migration. Curr Opin Cell Biol. 2001 Oct; 13(5):541-5.
    View in: PubMed
    Score: 0.179
  4. Mercurio AM, Bachelder RE, Chung J, O'Connor KL, Rabinovitz I, Shaw LM, Tani T. Integrin laminin receptors and breast carcinoma progression. J Mammary Gland Biol Neoplasia. 2001 Jul; 6(3):299-309.
    View in: PubMed
    Score: 0.176
  5. Mercurio AM, Rabinovitz I. Towards a mechanistic understanding of tumor invasion--lessons from the alpha6beta 4 integrin. Semin Cancer Biol. 2001 Apr; 11(2):129-41.
    View in: PubMed
    Score: 0.173
  6. Mercurio AM, Bachelder RE, Rabinovitz I, O'Connor KL, Tani T, Shaw LM. The metastatic odyssey: the integrin connection. Surg Oncol Clin N Am. 2001 Apr; 10(2):313-28, viii-ix.
    View in: PubMed
    Score: 0.173
  7. Lotz MM, Rabinovitz I, Mercurio AM. Intestinal restitution: progression of actin cytoskeleton rearrangements and integrin function in a model of epithelial wound healing. Am J Pathol. 2000 Mar; 156(3):985-96.
    View in: PubMed
    Score: 0.161
  8. O'Connor KL, Nguyen BK, Mercurio AM. RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism. J Cell Biol. 2000 Jan 24; 148(2):253-8.
    View in: PubMed
    Score: 0.160
  9. Bachelder RE, Ribick MJ, Marchetti A, Falcioni R, Soddu S, Davis KR, Mercurio AM. p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB. J Cell Biol. 1999 Nov 29; 147(5):1063-72.
    View in: PubMed
    Score: 0.158
  10. Rabinovitz I, Toker A, Mercurio AM. Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells. J Cell Biol. 1999 Sep 06; 146(5):1147-60.
    View in: PubMed
    Score: 0.155
  11. Bachelder RE, Marchetti A, Falcioni R, Soddu S, Mercurio AM. Activation of p53 function in carcinoma cells by the alpha6beta4 integrin. J Biol Chem. 1999 Jul 16; 274(29):20733-7.
    View in: PubMed
    Score: 0.154
  12. O'Connor KL, Shaw LM, Mercurio AM. Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells. J Cell Biol. 1998 Dec 14; 143(6):1749-60.
    View in: PubMed
    Score: 0.148
  13. Rabinovitz I, Mercurio AM. The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J Cell Biol. 1997 Dec 29; 139(7):1873-84.
    View in: PubMed
    Score: 0.138
  14. Shaw LM, Rabinovitz I, Wang HH, Toker A, Mercurio AM. Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. Cell. 1997 Dec 26; 91(7):949-60.
    View in: PubMed
    Score: 0.138
  15. Wewer UM, Shaw LM, Albrechtsen R, Mercurio AM. The integrin alpha 6 beta 1 promotes the survival of metastatic human breast carcinoma cells in mice. Am J Pathol. 1997 Nov; 151(5):1191-8.
    View in: PubMed
    Score: 0.137
  16. Wei J, Shaw LM, Mercurio AM. Integrin signaling in leukocytes: lessons from the alpha6beta1 integrin. J Leukoc Biol. 1997 Apr; 61(4):397-407.
    View in: PubMed
    Score: 0.131
  17. Lotz MM, Nusrat A, Madara JL, Ezzell R, Wewer UM, Mercurio AM. Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium. Am J Pathol. 1997 Feb; 150(2):747-60.
    View in: PubMed
    Score: 0.130
  18. Chao C, Lotz MM, Clarke AC, Mercurio AM. A function for the integrin alpha6beta4 in the invasive properties of colorectal carcinoma cells. Cancer Res. 1996 Oct 15; 56(20):4811-9.
    View in: PubMed
    Score: 0.127
  19. Shaw LM, Chao C, Wewer UM, Mercurio AM. Function of the integrin alpha 6 beta 1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor. Cancer Res. 1996 Mar 01; 56(5):959-63.
    View in: PubMed
    Score: 0.122
  20. Rabinovitz I, Mercurio AM. The integrin alpha 6 beta 4 and the biology of carcinoma. Biochem Cell Biol. 1996; 74(6):811-21.
    View in: PubMed
    Score: 0.120
  21. Shaw LM, Turner CE, Mercurio AM. The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins. J Biol Chem. 1995 Oct 06; 270(40):23648-52.
    View in: PubMed
    Score: 0.119
  22. Shaw LM, Mercurio AM. Regulation of alpha 6 beta 1 integrin-mediated migration in macrophages. Agents Actions Suppl. 1995; 47:101-6.
    View in: PubMed
    Score: 0.112
  23. Shaw LM, Mercurio AM. Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages. Mol Biol Cell. 1994 Jun; 5(6):679-90.
    View in: PubMed
    Score: 0.108
  24. Clarke AS, Lotz MM, Mercurio AM. A novel structural variant of the human beta 4 integrin cDNA. Cell Adhes Commun. 1994 Apr; 2(1):1-6.
    View in: PubMed
    Score: 0.107
  25. Shaw LM, Mercurio AM. Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit. J Cell Biol. 1993 Nov; 123(4):1017-25.
    View in: PubMed
    Score: 0.104
  26. Shaw LM, Lotz MM, Mercurio AM. Inside-out integrin signaling in macrophages. Analysis of the role of the alpha 6A beta 1 and alpha 6B beta 1 integrin variants in laminin adhesion by cDNA expression in an alpha 6 integrin-deficient macrophage cell line. J Biol Chem. 1993 May 25; 268(15):11401-8.
    View in: PubMed
    Score: 0.101
  27. Lee EC, Lotz MM, Steele GD, Mercurio AM. The integrin alpha 6 beta 4 is a laminin receptor. J Cell Biol. 1992 May; 117(3):671-8.
    View in: PubMed
    Score: 0.093
  28. Mercurio AM, Shaw LM. Laminin binding proteins. Bioessays. 1991 Sep; 13(9):469-73.
    View in: PubMed
    Score: 0.089
  29. Shaw LM, Messier JM, Mercurio AM. The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin. J Cell Biol. 1990 Jun; 110(6):2167-74.
    View in: PubMed
    Score: 0.082
  30. Lotz MM, Korzelius CA, Mercurio AM. Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins. Cell Regul. 1990 Feb; 1(3):249-57.
    View in: PubMed
    Score: 0.080
  31. Bates RC, Pursell BM, Mercurio AM. Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells. Cells Tissues Organs. 2007; 185(1-3):29-39.
    View in: PubMed
    Score: 0.065
  32. Lipscomb EA, Mercurio AM. Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression. Cancer Metastasis Rev. 2005 Sep; 24(3):413-23.
    View in: PubMed
    Score: 0.059
  33. Bates RC, Mercurio AM. The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther. 2005 Apr; 4(4):365-70.
    View in: PubMed
    Score: 0.057
  34. Mercurio AM. Lessons from the alpha2 integrin knockout mouse. Am J Pathol. 2002 Jul; 161(1):3-6.
    View in: PubMed
    Score: 0.047
  35. Gambaletta D, Marchetti A, Benedetti L, Mercurio AM, Sacchi A, Falcioni R. Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion. J Biol Chem. 2000 Apr 07; 275(14):10604-10.
    View in: PubMed
    Score: 0.040
  36. Chen MS, Almeida EA, Huovila AP, Takahashi Y, Shaw LM, Mercurio AM, White JM. Evidence that distinct states of the integrin alpha6beta1 interact with laminin and an ADAM. J Cell Biol. 1999 Feb 08; 144(3):549-61.
    View in: PubMed
    Score: 0.037
  37. Homan SM, Mercurio AM, LaFlamme SE. Endothelial cells assemble two distinct alpha6beta4-containing vimentin-associated structures: roles for ligand binding and the beta4 cytoplasmic tail. J Cell Sci. 1998 Sep; 111 ( Pt 18):2717-28.
    View in: PubMed
    Score: 0.036
  38. Carloni V, Romanelli RG, Mercurio AM, Pinzani M, Laffi G, Cotrozzi G, Gentilini P. Knockout of alpha6 beta1-integrin expression reverses the transformed phenotype of hepatocarcinoma cells. Gastroenterology. 1998 Aug; 115(2):433-42.
    View in: PubMed
    Score: 0.036
  39. Yoshii T, Geng Y, Peyton S, Mercurio AM, Rotello VM. Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine. Drug Discov Today. 2016 09; 21(9):1489-1494.
    View in: PubMed
    Score: 0.031
  40. Clarke AS, Lotz MM, Chao C, Mercurio AM. Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain. J Biol Chem. 1995 Sep 29; 270(39):22673-6.
    View in: PubMed
    Score: 0.030
  41. Almeida EA, Huovila AP, Sutherland AE, Stephens LE, Calarco PG, Shaw LM, Mercurio AM, Sonnenberg A, Primakoff P, Myles DG, White JM. Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. Cell. 1995 Jun 30; 81(7):1095-104.
    View in: PubMed
    Score: 0.029
  42. Barney LE, Dandley EC, Jansen LE, Reich NG, Mercurio AM, Peyton SR. A cell-ECM screening method to predict breast cancer metastasis. Integr Biol (Camb). 2015 Feb; 7(2):198-212.
    View in: PubMed
    Score: 0.028
  43. T?zeren A, Kleinman HK, Wu S, Mercurio AM, Byers SW. Integrin alpha 6 beta 4 mediates dynamic interactions with laminin. J Cell Sci. 1994 Nov; 107 ( Pt 11):3153-63.
    View in: PubMed
    Score: 0.028
  44. Rossen K, Dahlstr?m KK, Mercurio AM, Wewer UM. Expression of the alpha 6 beta 4 integrin by squamous cell carcinomas and basal cell carcinomas: possible relation to invasive potential? Acta Derm Venereol. 1994 Mar; 74(2):101-5.
    View in: PubMed
    Score: 0.027
  45. Mercurio AM. Laminin: multiple forms, multiple receptors. Curr Opin Cell Biol. 1990 Oct; 2(5):845-9.
    View in: PubMed
    Score: 0.021
  46. Morena A, Riccioni S, Marchetti A, Polcini AT, Mercurio AM, Blandino G, Sacchi A, Falcioni R. Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells. Blood. 2002 Jul 01; 100(1):96-106.
    View in: PubMed
    Score: 0.012
  47. T?zeren A, Kleinman HK, Grant DS, Morales D, Mercurio AM, Byers SW. E-selectin-mediated dynamic interactions of breast- and colon-cancer cells with endothelial-cell monolayers. Int J Cancer. 1995 Jan 27; 60(3):426-31.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.