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Connection

Mark Alkema to Caenorhabditis elegans

This is a "connection" page, showing publications Mark Alkema has written about Caenorhabditis elegans.
Connection Strength

5.624
  1. Yin X, Wang R, Thackeray A, Baehrecke EH, Alkema MJ. VPS13D mutations affect mitochondrial homeostasis and locomotion in Caenorhabditis elegans. G3 (Bethesda). 2025 Apr 17; 15(4).
    View in: PubMed
    Score: 0.615
  2. De Rosa MJ, Veuthey T, Florman J, Grant J, Blanco MG, Andersen N, Donnelly J, Rayes D, Alkema MJ. The flight response impairs cytoprotective mechanisms by activating the insulin pathway. Nature. 2019 09; 573(7772):135-138.
    View in: PubMed
    Score: 0.416
  3. Huang YC, Pirri JK, Rayes D, Gao S, Mulcahy B, Grant J, Saheki Y, Francis MM, Zhen M, Alkema MJ. Gain-of-function mutations in the UNC-2/CaV2a channel lead to excitation-dominant synaptic transmission in Caenorhabditis elegans. Elife. 2019 08 05; 8.
    View in: PubMed
    Score: 0.414
  4. Rayes D, Alkema MJ. Imprinting: When Early Life Memories Make Food Smell Bad. Curr Biol. 2016 05 09; 26(9):R362-4.
    View in: PubMed
    Score: 0.331
  5. Pirri JK, Rayes D, Alkema MJ. A Change in the Ion Selectivity of Ligand-Gated Ion Channels Provides a Mechanism to Switch Behavior. PLoS Biol. 2015; 13(9):e1002238.
    View in: PubMed
    Score: 0.316
  6. Donnelly JL, Clark CM, Leifer AM, Pirri JK, Haburcak M, Francis MM, Samuel AD, Alkema MJ. Monoaminergic orchestration of motor programs in a complex C. elegans behavior. PLoS Biol. 2013; 11(4):e1001529.
    View in: PubMed
    Score: 0.267
  7. Pirri JK, Alkema MJ. The neuroethology of C. elegans escape. Curr Opin Neurobiol. 2012 Apr; 22(2):187-93.
    View in: PubMed
    Score: 0.245
  8. Maguire SM, Clark CM, Nunnari J, Pirri JK, Alkema MJ. The C. elegans touch response facilitates escape from predacious fungi. Curr Biol. 2011 Aug 09; 21(15):1326-30.
    View in: PubMed
    Score: 0.238
  9. Pirri JK, McPherson AD, Donnelly JL, Francis MM, Alkema MJ. A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron. 2009 May 28; 62(4):526-38.
    View in: PubMed
    Score: 0.204
  10. Alkema MJ. Oxygen sensation: into thick air. Curr Biol. 2009 May 26; 19(10):R407-9.
    View in: PubMed
    Score: 0.204
  11. Veuthey T, Florman JT, Giunti S, Romussi S, De Rosa MJ, Alkema MJ, Rayes D. The neurohormone tyramine stimulates the secretion of an insulin-like peptide from the Caenorhabditis elegans intestine to modulate the systemic stress response. PLoS Biol. 2025 Jan; 23(1):e3002997.
    View in: PubMed
    Score: 0.151
  12. Kang WK, Florman JT, Araya A, Fox BW, Thackeray A, Schroeder FC, Walhout AJM, Alkema MJ. Vitamin B12 produced by gut bacteria modulates cholinergic signalling. Nat Cell Biol. 2024 Jan; 26(1):72-85.
    View in: PubMed
    Score: 0.141
  13. Hernandez-Cravero B, Gallino S, Florman J, Vranych C, Diaz P, Elgoyhen AB, Alkema MJ, de Mendoza D. Cannabinoids activate the insulin pathway to modulate mobilization of cholesterol in C. elegans. PLoS Genet. 2022 11; 18(11):e1010346.
    View in: PubMed
    Score: 0.130
  14. Wirak GS, Florman J, Alkema MJ, Connor CW, Gabel CV. Age-associated changes to neuronal dynamics involve a disruption of excitatory/inhibitory balance in C. elegans. Elife. 2022 06 15; 11.
    View in: PubMed
    Score: 0.126
  15. Florman JT, Alkema MJ. Co-transmission of neuropeptides and monoamines choreograph the C. elegans escape response. PLoS Genet. 2022 03; 18(3):e1010091.
    View in: PubMed
    Score: 0.124
  16. Ramachandran S, Banerjee N, Bhattacharya R, Lemons ML, Florman J, Lambert CM, Touroutine D, Alexander K, Schoofs L, Alkema MJ, Beets I, Francis MM. A conserved neuropeptide system links head and body motor circuits to enable adaptive behavior. Elife. 2021 11 12; 10.
    View in: PubMed
    Score: 0.121
  17. Reilly DK, McGlame EJ, Vandewyer E, Robidoux AN, Muirhead CS, Northcott HT, Joyce W, Alkema MJ, Gegear RJ, Beets I, Srinivasan J. Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone. Commun Biol. 2021 08 31; 4(1):1018.
    View in: PubMed
    Score: 0.120
  18. Maicas M, Jimeno-Mart?n ?, Mill?n-Trejo A, Alkema MJ, Flames N. The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons. PLoS Biol. 2021 07; 19(7):e3001334.
    View in: PubMed
    Score: 0.118
  19. Ji N, Venkatachalam V, Rodgers HD, Hung W, Kawano T, Clark CM, Lim M, Alkema MJ, Zhen M, Samuel AD. Corollary discharge promotes a sustained motor state in a neural circuit for navigation. Elife. 2021 04 21; 10.
    View in: PubMed
    Score: 0.117
  20. Wang Y, Zhang X, Xin Q, Hung W, Florman J, Huo J, Xu T, Xie Y, Alkema MJ, Zhen M, Wen Q. Flexible motor sequence generation during stereotyped escape responses. Elife. 2020 06 05; 9.
    View in: PubMed
    Score: 0.110
  21. Chute CD, DiLoreto EM, Zhang YK, Reilly DK, Rayes D, Coyle VL, Choi HJ, Alkema MJ, Schroeder FC, Srinivasan J. Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans. Nat Commun. 2019 07 18; 10(1):3186.
    View in: PubMed
    Score: 0.103
  22. Philbrook A, Ramachandran S, Lambert CM, Oliver D, Florman J, Alkema MJ, Lemons M, Francis MM. Neurexin directs partner-specific synaptic connectivity in C. elegans. Elife. 2018 07 24; 7.
    View in: PubMed
    Score: 0.096
  23. Gao S, Guan SA, Fouad AD, Meng J, Kawano T, Huang YC, Li Y, Alcaire S, Hung W, Lu Y, Qi YB, Jin Y, Alkema M, Fang-Yen C, Zhen M. Excitatory motor neurons are local oscillators for backward locomotion. Elife. 2018 01 23; 7.
    View in: PubMed
    Score: 0.093
  24. Romanelli-Cedrez L, Carrera I, Otero L, Miranda-Vizuete A, Mariotti M, Alkema MJ, Salinas G. Selenoprotein T is required for pathogenic bacteria avoidance in Caenorhabditis elegans. Free Radic Biol Med. 2017 07; 108:174-182.
    View in: PubMed
    Score: 0.088
  25. Cook DE, Zdraljevic S, Tanny RE, Seo B, Riccardi DD, Noble LM, Rockman MV, Alkema MJ, Braendle C, Kammenga JE, Wang J, Kruglyak L, F?lix MA, Lee J, Andersen EC. The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length. Genetics. 2016 09; 204(1):371-83.
    View in: PubMed
    Score: 0.084
  26. Venkatachalam V, Ji N, Wang X, Clark C, Mitchell JK, Klein M, Tabone CJ, Florman J, Ji H, Greenwood J, Chisholm AD, Srinivasan J, Alkema M, Zhen M, Samuel AD. Pan-neuronal imaging in roaming Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):E1082-8.
    View in: PubMed
    Score: 0.081
  27. Nagy S, Huang YC, Alkema MJ, Biron D. Caenorhabditis elegans exhibit a coupling between the defecation motor program and directed locomotion. Sci Rep. 2015 Nov 24; 5:17174.
    View in: PubMed
    Score: 0.080
  28. Fang-Yen C, Alkema MJ, Samuel AD. Illuminating neural circuits and behaviour in Caenorhabditis elegans with optogenetics. Philos Trans R Soc Lond B Biol Sci. 2015 Sep 19; 370(1677):20140212.
    View in: PubMed
    Score: 0.079
  29. Gao S, Xie L, Kawano T, Po MD, Guan S, Zhen M, Pirri JK, Alkema MJ. The NCA sodium leak channel is required for persistent motor circuit activity that sustains locomotion. Nat Commun. 2015 Feb 26; 6:6323.
    View in: PubMed
    Score: 0.076
  30. Schumacher JA, Hsieh YW, Chen S, Pirri JK, Alkema MJ, Li WH, Chang C, Chuang CF. Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans. Development. 2012 Nov; 139(22):4191-201.
    View in: PubMed
    Score: 0.065
  31. Leifer AM, Fang-Yen C, Gershow M, Alkema MJ, Samuel AD. Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans. Nat Methods. 2011 Feb; 8(2):147-52.
    View in: PubMed
    Score: 0.057
  32. Grove CA, De Masi F, Barrasa MI, Newburger DE, Alkema MJ, Bulyk ML, Walhout AJ. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell. 2009 Jul 23; 138(2):314-27.
    View in: PubMed
    Score: 0.052
  33. Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR. Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. Neuron. 2005 Apr 21; 46(2):247-60.
    View in: PubMed
    Score: 0.038
  34. Caneo M, Julian V, Byrne AB, Alkema MJ, Calixto A. Diapause induces functional axonal regeneration after necrotic insult in C. elegans. PLoS Genet. 2019 01; 15(1):e1007863.
    View in: PubMed
    Score: 0.025
  35. Awal MR, Austin D, Florman J, Alkema M, Gabel CV, Connor CW. Breakdown of Neural Function under Isoflurane Anesthesia: In Vivo, Multineuronal Imaging in Caenorhabditis elegans. Anesthesiology. 2018 10; 129(4):733-743.
    View in: PubMed
    Score: 0.024
  36. Oh KH, Abraham LS, Gegg C, Silvestri C, Huang YC, Alkema MJ, Furst J, Raicu D, Kim H. Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels. BMC Neurosci. 2015 Apr 24; 16:26.
    View in: PubMed
    Score: 0.019
  37. Sun L, Shay J, McLoed M, Roodhouse K, Chung SH, Clark CM, Pirri JK, Alkema MJ, Gabel CV. Neuronal regeneration in C. elegans requires subcellular calcium release by ryanodine receptor channels and can be enhanced by optogenetic stimulation. J Neurosci. 2014 Nov 26; 34(48):15947-56.
    View in: PubMed
    Score: 0.019
  38. Bhattacharya R, Touroutine D, Barbagallo B, Climer J, Lambert CM, Clark CM, Alkema MJ, Francis MM. A conserved dopamine-cholecystokinin signaling pathway shapes context-dependent Caenorhabditis elegans behavior. PLoS Genet. 2014 Aug; 10(8):e1004584.
    View in: PubMed
    Score: 0.018
  39. Shipley FB, Clark CM, Alkema MJ, Leifer AM. Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans. Front Neural Circuits. 2014; 8:28.
    View in: PubMed
    Score: 0.018
Connection Strength

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