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Connection

Jae-Hyuck Shim to Osteoblasts

This is a "connection" page, showing publications Jae-Hyuck Shim has written about Osteoblasts.
Connection Strength

3.298
  1. Kim JM, Lin C, Stavre Z, Greenblatt MB, Shim JH. Osteoblast-Osteoclast Communication and Bone Homeostasis. Cells. 2020 09 10; 9(9).
    View in: PubMed
    Score: 0.626
  2. Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep; 123(9):4010-22.
    View in: PubMed
    Score: 0.383
  3. Lin C, Yang YS, Ma H, Chen Z, Chen D, John AA, Xie J, Gao G, Shim JH. Engineering a targeted and safe bone anabolic gene therapy to treat osteoporosis in alveolar bone loss. Mol Ther. 2024 Sep 04; 32(9):3080-3100.
    View in: PubMed
    Score: 0.203
  4. Kim JM, Yang YS, Hong J, Chaugule S, Chun H, van der Meulen MCH, Xu R, Greenblatt MB, Shim JH. Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway. Elife. 2022 08 17; 11.
    View in: PubMed
    Score: 0.179
  5. Kim JM, Yang YS, Xie J, Lee O, Kim J, Hong J, Boldyreff B, Filhol O, Chun H, Greenblatt MB, Gao G, Shim JH. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes. Cell Death Differ. 2022 08; 29(8):1625-1638.
    View in: PubMed
    Score: 0.173
  6. Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).
    View in: PubMed
    Score: 0.168
  7. Sun J, Shin DY, Eiseman M, Yallowitz AR, Li N, Lalani S, Li Z, Cung M, Bok S, Debnath S, Marquez SJ, White TE, Khan AG, Lorenz IC, Shim JH, Lee FS, Xu R, Greenblatt MB. SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts. Nat Commun. 2021 07 29; 12(1):4611.
    View in: PubMed
    Score: 0.166
  8. Li Z, Oh H, Cung M, Marquez SJ, Sun J, Hammad H, Janssens S, Pouliot P, Lambrecht BN, Yang YS, Shim JH, Greenblatt MB. TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization. Biochem Biophys Res Commun. 2020 10 22; 531(4):497-502.
    View in: PubMed
    Score: 0.156
  9. Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020 05 08; 11(1):2289.
    View in: PubMed
    Score: 0.153
  10. Yang YS, Xie J, Wang D, Kim JM, Tai PWL, Gravallese E, Gao G, Shim JH. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nat Commun. 2019 07 04; 10(1):2958.
    View in: PubMed
    Score: 0.144
  11. Kim JM, Yang YS, Park KH, Oh H, Greenblatt MB, Shim JH. The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis. Int J Mol Sci. 2019 Apr 12; 20(8).
    View in: PubMed
    Score: 0.142
  12. Xu R, Zhang C, Shin DY, Kim JM, Lalani S, Li N, Yang YS, Liu Y, Eiseman M, Davis RJ, Shim JH, Greenblatt MB. c-Jun N-Terminal Kinases (JNKs) Are Critical Mediators of Osteoblast Activity In Vivo. J Bone Miner Res. 2017 Sep; 32(9):1811-1815.
    View in: PubMed
    Score: 0.127
  13. Greenblatt MB, Shin DY, Oh H, Lee KY, Zhai B, Gygi SP, Lotinun S, Baron R, Liu D, Su B, Glimcher LH, Shim JH. MEKK2 mediates an alternative ?-catenin pathway that promotes bone formation. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):E1226-35.
    View in: PubMed
    Score: 0.114
  14. Greenblatt MB, Park KH, Oh H, Kim JM, Shin DY, Lee JM, Lee JW, Singh A, Lee KY, Hu D, Xiao C, Charles JF, Penninger JM, Lotinun S, Baron R, Ghosh S, Shim JH. CHMP5 controls bone turnover rates by dampening NF-?B activity in osteoclasts. J Exp Med. 2015 Jul 27; 212(8):1283-301.
    View in: PubMed
    Score: 0.110
  15. Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annu Rev Cell Dev Biol. 2013; 29:63-79.
    View in: PubMed
    Score: 0.094
  16. Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH. Control of bone resorption in mice by Schnurri-3. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8173-8.
    View in: PubMed
    Score: 0.088
  17. Shim JH, Greenblatt MB, Singh A, Brady N, Hu D, Drapp R, Ogawa W, Kasuga M, Noda T, Yang SH, Lee SK, Rebel VI, Glimcher LH. Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. J Clin Invest. 2012 Jan; 122(1):91-106.
    View in: PubMed
    Score: 0.085
  18. Park Y, Cheong E, Kwak JG, Carpenter R, Shim JH, Lee J. Trabecular bone organoid model for studying the regulation of localized bone remodeling. Sci Adv. 2021 01; 7(4).
    View in: PubMed
    Score: 0.040
  19. Bok S, Shin DY, Yallowitz AR, Eiseman M, Cung M, Xu R, Li N, Sun J, Williams AL, Scott JE, Su B, Shim JH, Greenblatt MB. MEKK2 mediates aberrant ERK activation in neurofibromatosis type I. Nat Commun. 2020 11 11; 11(1):5704.
    View in: PubMed
    Score: 0.040
  20. Debnath S, Yallowitz AR, McCormick J, Lalani S, Zhang T, Xu R, Li N, Liu Y, Yang YS, Eiseman M, Shim JH, Hameed M, Healey JH, Bostrom MP, Landau DA, Greenblatt MB. Discovery of a periosteal stem cell mediating intramembranous bone formation. Nature. 2018 10; 562(7725):133-139.
    View in: PubMed
    Score: 0.034
  21. Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018 06; 24(6):823-833.
    View in: PubMed
    Score: 0.033
  22. Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice. J Clin Invest. 2011 Nov; 121(11):4383-92.
    View in: PubMed
    Score: 0.021
  23. Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R, Glimcher LH. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest. 2010 Jul; 120(7):2457-73.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.