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Connection

Jae-Hyuck Shim to Osteogenesis

This is a "connection" page, showing publications Jae-Hyuck Shim has written about Osteogenesis.
Connection Strength

5.278
  1. Kim JM, Yang YS, Xie J, Kang CM, Cho YC, Park KH, Gong F, Sato T, Kim BJ, Gao G, Shim JH. USP24-dependent STAT2 stabilization mediates physiologic and pathologic bone formation. Cell Death Dis. 2026 May 30; 17(1).
    View in: PubMed
    Score: 0.881
  2. Kim JM, Yang YS, Hong J, Chaugule S, Chun H, van der Meulen MCH, Xu R, Greenblatt MB, Shim JH. Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway. Elife. 2022 08 17; 11.
    View in: PubMed
    Score: 0.677
  3. Chaugule S, Kim JM, Yang YS, Knobeloch KP, He X, Shim JH. Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling. Int J Mol Sci. 2021 Sep 24; 22(19).
    View in: PubMed
    Score: 0.637
  4. Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020 05 08; 11(1):2289.
    View in: PubMed
    Score: 0.579
  5. Shim JH, Stavre Z, Gravallese EM. Bone Loss in Rheumatoid Arthritis: Basic Mechanisms and Clinical Implications. Calcif Tissue Int. 2018 05; 102(5):533-546.
    View in: PubMed
    Score: 0.489
  6. Chaugule S, Yang YS, Sato T, Mayer E, Shim JH. USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development. Cell Mol Life Sci. 2026 Jan 15; 83(1):72.
    View in: PubMed
    Score: 0.215
  7. Zhang F, Wang Y, Zhang L, Wang C, Chen D, Liu H, Xu R, Haynes CM, Shim JH, Ge X. The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence. Elife. 2025 Jul 07; 13.
    View in: PubMed
    Score: 0.207
  8. Yang YS, Lin C, Ma H, Xie J, Kaplan FS, Gao G, Shim JH. AAV-Mediated Targeting of the Activin A-ACVR1R206H Signaling in Fibrodysplasia Ossificans Progressiva. Biomolecules. 2023 09 08; 13(9).
    View in: PubMed
    Score: 0.182
  9. Stavre Z, Kim JM, Yang YS, N?ndel K, Chaugule S, Sato T, Park KH, Gao G, Gravallese EM, Shim JH. Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis. Proc Natl Acad Sci U S A. 2023 05 09; 120(19):e2218019120.
    View in: PubMed
    Score: 0.178
  10. Lin C, Yang Q, Guo D, Xie J, Yang YS, Chaugule S, DeSouza N, Oh WT, Li R, Chen Z, John AA, Qiu Q, Zhu LJ, Greenblatt MB, Ghosh S, Li S, Gao G, Haynes C, Emerson CP, Shim JH. Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nat Commun. 2022 11 11; 13(1):6869.
    View in: PubMed
    Score: 0.172
  11. Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong J, Chun H, Shore EM, Kaplan FS, Gao G, Shim JH. Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nat Commun. 2022 10 19; 13(1):6175.
    View in: PubMed
    Score: 0.171
  12. Kim JM, Yang YS, Xie J, Lee O, Kim J, Hong J, Boldyreff B, Filhol O, Chun H, Greenblatt MB, Gao G, Shim JH. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes. Cell Death Differ. 2022 08; 29(8):1625-1638.
    View in: PubMed
    Score: 0.164
  13. Sun J, Shin DY, Eiseman M, Yallowitz AR, Li N, Lalani S, Li Z, Cung M, Bok S, Debnath S, Marquez SJ, White TE, Khan AG, Lorenz IC, Shim JH, Lee FS, Xu R, Greenblatt MB. SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts. Nat Commun. 2021 07 29; 12(1):4611.
    View in: PubMed
    Score: 0.157
  14. Kim JM, Yang YS, Park KH, Oh H, Greenblatt MB, Shim JH. The ERK MAPK Pathway Is Essential for Skeletal Development and Homeostasis. Int J Mol Sci. 2019 Apr 12; 20(8).
    View in: PubMed
    Score: 0.134
  15. Xu R, Zhang C, Shin DY, Kim JM, Lalani S, Li N, Yang YS, Liu Y, Eiseman M, Davis RJ, Shim JH, Greenblatt MB. c-Jun N-Terminal Kinases (JNKs) Are Critical Mediators of Osteoblast Activity In Vivo. J Bone Miner Res. 2017 Sep; 32(9):1811-1815.
    View in: PubMed
    Score: 0.120
  16. Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. J Clin Invest. 2013 Sep; 123(9):4010-22.
    View in: PubMed
    Score: 0.091
  17. Zhytnik L, Ventura L, Sclocco A, Verhage M, Bakker AD, Shim JH, Beaino W, Pereira PM, Hoogeland ME, Heine VM, Maas H, Jaspers RT, Niehoff A, Zaucke F, de Waard V, Eekhoff EMW, Micha D. New lens on congenital mild bone fragility: a novel Col1a1 knockout mouse model for osteogenesis imperfecta type 1. J Bone Miner Res. 2026 Apr 26; 41(5):565-580.
    View in: PubMed
    Score: 0.055
  18. Sarkar A, Sarkar S, Anwar A, Kim JW, Shim JH, John AA. The Growing Significance of microRNAs in Osteoporosis. Cells. 2025 12 01; 14(23).
    View in: PubMed
    Score: 0.053
  19. Yallowitz AR, Shim JH, Xu R, Greenblatt MB. An angiogenic approach to osteoanabolic therapy targeting the SHN3-SLIT3 pathway. Bone. 2023 07; 172:116761.
    View in: PubMed
    Score: 0.044
  20. Xu R, Yallowitz A, Qin A, Wu Z, Shin DY, Kim JM, Debnath S, Ji G, Bostrom MP, Yang X, Zhang C, Dong H, Kermani P, Lalani S, Li N, Liu Y, Poulos MG, Wach A, Zhang Y, Inoue K, Di Lorenzo A, Zhao B, Butler JM, Shim JH, Glimcher LH, Greenblatt MB. Targeting skeletal endothelium to ameliorate bone loss. Nat Med. 2018 06; 24(6):823-833.
    View in: PubMed
    Score: 0.032
  21. Greenblatt MB, Shim JH, Glimcher LH. Mitogen-activated protein kinase pathways in osteoblasts. Annu Rev Cell Dev Biol. 2013; 29:63-79.
    View in: PubMed
    Score: 0.022
  22. Greenblatt MB, Shim JH, Zou W, Sitara D, Schweitzer M, Hu D, Lotinun S, Sano Y, Baron R, Park JM, Arthur S, Xie M, Schneider MD, Zhai B, Gygi S, Davis R, Glimcher LH. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest. 2010 Jul; 120(7):2457-73.
    View in: PubMed
    Score: 0.018
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.