Header Logo

Connection

Arthur Krieg to Lymphocyte Activation

This is a "connection" page, showing publications Arthur Krieg has written about Lymphocyte Activation.
Connection Strength

2.161
  1. Krieg AM. TLR9 and DNA 'feel' RAGE. Nat Immunol. 2007 May; 8(5):475-7.
    View in: PubMed
    Score: 0.223
  2. Vollmer J, Weeratna RD, Jurk M, Davis HL, Schetter C, W?llner M, Wader T, Liu M, Kritzler A, Krieg AM. Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity. J Leukoc Biol. 2004 Sep; 76(3):585-93.
    View in: PubMed
    Score: 0.183
  3. Hartmann G, Weeratna RD, Ballas ZK, Payette P, Blackwell S, Suparto I, Rasmussen WL, Waldschmidt M, Sajuthi D, Purcell RH, Davis HL, Krieg AM. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol. 2000 Feb 01; 164(3):1617-24.
    View in: PubMed
    Score: 0.135
  4. Hartmann G, Krieg AM. CpG DNA and LPS induce distinct patterns of activation in human monocytes. Gene Ther. 1999 May; 6(5):893-903.
    View in: PubMed
    Score: 0.128
  5. Redford TW, Yi AK, Ward CT, Krieg AM. Cyclosporin A enhances IL-12 production by CpG motifs in bacterial DNA and synthetic oligodeoxynucleotides. J Immunol. 1998 Oct 15; 161(8):3930-5.
    View in: PubMed
    Score: 0.123
  6. Ballas ZK, Rasmussen WL, Krieg AM. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol. 1996 Sep 01; 157(5):1840-5.
    View in: PubMed
    Score: 0.106
  7. Krieg AM. Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA. Trends Microbiol. 1996 Feb; 4(2):73-6.
    View in: PubMed
    Score: 0.102
  8. Yi AK, Chace JH, Cowdery JS, Krieg AM. IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides. J Immunol. 1996 Jan 15; 156(2):558-64.
    View in: PubMed
    Score: 0.102
  9. Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 1995 Apr 06; 374(6522):546-9.
    View in: PubMed
    Score: 0.097
  10. Fourcade J, Sun Z, Pagliano O, Chauvin JM, Sander C, Janjic B, Tarhini AA, Tawbi HA, Kirkwood JM, Moschos S, Wang H, Guillaume P, Luescher IF, Krieg A, Anderson AC, Kuchroo VK, Zarour HM. PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8? T cells induced by melanoma vaccines. Cancer Res. 2014 Feb 15; 74(4):1045-55.
    View in: PubMed
    Score: 0.088
  11. Krieg AM, Gause WC, Gourley MF, Steinberg AD. A role for endogenous retroviral sequences in the regulation of lymphocyte activation. J Immunol. 1989 Oct 15; 143(8):2448-51.
    View in: PubMed
    Score: 0.066
  12. Appay V, Jandus C, Voelter V, Reynard S, Coupland SE, Rimoldi D, Lienard D, Guillaume P, Krieg AM, Cerottini JC, Romero P, Leyvraz S, Rufer N, Speiser DE. New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site. J Immunol. 2006 Aug 01; 177(3):1670-8.
    View in: PubMed
    Score: 0.053
  13. Speiser DE, Li?nard D, Rufer N, Rubio-Godoy V, Rimoldi D, Lejeune F, Krieg AM, Cerottini JC, Romero P. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest. 2005 Mar; 115(3):739-46.
    View in: PubMed
    Score: 0.048
  14. Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J Immunol. 2004 Oct 01; 173(7):4433-42.
    View in: PubMed
    Score: 0.047
  15. Sandler AD, Chihara H, Kobayashi G, Zhu X, Miller MA, Scott DL, Krieg AM. CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma. Cancer Res. 2003 Jan 15; 63(2):394-9.
    View in: PubMed
    Score: 0.041
  16. Rothenfusser S, Hornung V, Krug A, Towarowski A, Krieg AM, Endres S, Hartmann G. Distinct CpG oligonucleotide sequences activate human gamma delta T cells via interferon-alpha/-beta. Eur J Immunol. 2001 Dec; 31(12):3525-34.
    View in: PubMed
    Score: 0.038
  17. Jahrsd?rfer B, Hartmann G, Racila E, Jackson W, M?hlenhoff L, Meinhardt G, Endres S, Link BK, Krieg AM, Weiner GJ. CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens. J Leukoc Biol. 2001 Jan; 69(1):81-8.
    View in: PubMed
    Score: 0.036
  18. Warren TL, Bhatia SK, Acosta AM, Dahle CE, Ratliff TL, Krieg AM, Weiner GJ. APC stimulated by CpG oligodeoxynucleotide enhance activation of MHC class I-restricted T cells. J Immunol. 2000 Dec 01; 165(11):6244-51.
    View in: PubMed
    Score: 0.036
  19. Brunner C, Seiderer J, Schlamp A, Bidlingmaier M, Eigler A, Haimerl W, Lehr HA, Krieg AM, Hartmann G, Endres S. Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo. J Immunol. 2000 Dec 01; 165(11):6278-86.
    View in: PubMed
    Score: 0.036
  20. Hartmann G, Krieg AM. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol. 2000 Jan 15; 164(2):944-53.
    View in: PubMed
    Score: 0.034
  21. Krieg AM. Signal transduction induced by immunostimulatory CpG DNA. Springer Semin Immunopathol. 2000; 22(1-2):97-105.
    View in: PubMed
    Score: 0.034
  22. Krieg AM. Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides. Biochim Biophys Acta. 1999 Dec 10; 1489(1):107-16.
    View in: PubMed
    Score: 0.033
  23. Yi AK, Peckham DW, Ashman RF, Krieg AM. CpG DNA rescues B cells from apoptosis by activating NFkappaB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway. Int Immunol. 1999 Dec; 11(12):2015-24.
    View in: PubMed
    Score: 0.033
  24. Hartmann G, Weiner GJ, Krieg AM. CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells. Proc Natl Acad Sci U S A. 1999 Aug 03; 96(16):9305-10.
    View in: PubMed
    Score: 0.033
  25. Krieg AM, Yi AK, Schorr J, Davis HL. The role of CpG dinucleotides in DNA vaccines. Trends Microbiol. 1998 Jan; 6(1):23-7.
    View in: PubMed
    Score: 0.029
  26. Ishigatsubo Y, Steinberg AD, Krieg A, Klinman DM. Increased utilization of polyreactive B cells during periods of generalized immune activation. Autoimmunity. 1995; 22(2):113-9.
    View in: PubMed
    Score: 0.024
  27. Mojcik CF, Gourley MF, Klinman DM, Krieg AM, Gmelig-Meyling F, Steinberg AD. Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner. Clin Immunol Immunopathol. 1993 May; 67(2):130-6.
    View in: PubMed
    Score: 0.021
  28. Krieg AM, Tonkinson J, Matson S, Zhao Q, Saxon M, Zhang LM, Bhanja U, Yakubov L, Stein CA. Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):1048-52.
    View in: PubMed
    Score: 0.021
  29. Krieg AM, Gourley MF, Klinman DM, Perl A, Steinberg AD. Heterogeneous expression and coordinate regulation of endogenous retroviral sequences in human peripheral blood mononuclear cells. AIDS Res Hum Retroviruses. 1992 Dec; 8(12):1991-8.
    View in: PubMed
    Score: 0.021
  30. Krieg AM, Gmelig-Meyling F, Gourley MF, Kisch WJ, Chrisey LA, Steinberg AD. Uptake of oligodeoxyribonucleotides by lymphoid cells is heterogeneous and inducible. Antisense Res Dev. 1991; 1(2):161-71.
    View in: PubMed
    Score: 0.018
  31. Richardt-Pargmann D, Wechsler M, Krieg AM, Vollmer J, Jurk M. Positive T cell co-stimulation by TLR7/8 ligands is dependent on the cellular environment. Immunobiology. 2011 Jan-Feb; 216(1-2):12-23.
    View in: PubMed
    Score: 0.017
  32. Elkins KL, Colombini SM, Krieg AM, De Pascalis R. NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS. Microbes Infect. 2009 Jan; 11(1):49-56.
    View in: PubMed
    Score: 0.015
  33. Martinson JA, Tenorio AR, Montoya CJ, Al-Harthi L, Gichinga CN, Krieg AM, Baum LL, Landay AL. Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals. Immunology. 2007 Apr; 120(4):526-35.
    View in: PubMed
    Score: 0.014
  34. Booth JS, Nichani AK, Benjamin P, Dar A, Krieg AM, Babiuk LA, Mutwiri GK. Innate immune responses induced by classes of CpG oligodeoxynucleotides in ovine lymph node and blood mononuclear cells. Vet Immunol Immunopathol. 2007 Jan 15; 115(1-2):24-34.
    View in: PubMed
    Score: 0.013
  35. Montoya CJ, Jie HB, Al-Harthi L, Mulder C, Pati?o PJ, Rugeles MT, Krieg AM, Landay AL, Wilson SB. Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells. J Immunol. 2006 Jul 15; 177(2):1028-39.
    View in: PubMed
    Score: 0.013
  36. Cooper CL, Davis HL, Angel JB, Morris ML, Elfer SM, Seguin I, Krieg AM, Cameron DW. CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults. AIDS. 2005 Sep 23; 19(14):1473-9.
    View in: PubMed
    Score: 0.012
  37. Lenert P, Yi AK, Krieg AM, Stunz LL, Ashman RF. Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells. Antisense Nucleic Acid Drug Dev. 2003; 13(3):143-50.
    View in: PubMed
    Score: 0.010
  38. Miconnet I, Koenig S, Speiser D, Krieg A, Guillaume P, Cerottini JC, Romero P. CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide. J Immunol. 2002 Feb 01; 168(3):1212-8.
    View in: PubMed
    Score: 0.010
  39. Pontarollo RA, Rankin R, Babiuk LA, Godson DL, Griebel PJ, Hecker R, Krieg AM, van Drunen Littel-van den Hurk S. Monocytes are required for optimum in vitro stimulation of bovine peripheral blood mononuclear cells by non-methylated CpG motifs. Vet Immunol Immunopathol. 2002 Jan 01; 84(1-2):43-59.
    View in: PubMed
    Score: 0.010
  40. Krug A, Towarowski A, Britsch S, Rothenfusser S, Hornung V, Bals R, Giese T, Engelmann H, Endres S, Krieg AM, Hartmann G. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol. 2001 Oct; 31(10):3026-37.
    View in: PubMed
    Score: 0.009
  41. Lenert P, Stunz L, YI AK, Krieg AM, Ashman RF. CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation. Antisense Nucleic Acid Drug Dev. 2001 Aug; 11(4):247-56.
    View in: PubMed
    Score: 0.009
  42. Kovarik J, Bozzotti P, Tougne C, Davis HL, Lambert PH, Krieg AM, Siegrist CA. Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens. Immunology. 2001 Jan; 102(1):67-76.
    View in: PubMed
    Score: 0.009
  43. McCluskie MJ, Weeratna RD, Krieg AM, Davis HL. CpG DNA is an effective oral adjuvant to protein antigens in mice. Vaccine. 2000 Nov 22; 19(7-8):950-7.
    View in: PubMed
    Score: 0.009
  44. Davis HL, Weeratna R, Waldschmidt TJ, Tygrett L, Schorr J, Krieg AM, Weeranta R. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol. 1998 Jan 15; 160(2):870-6.
    View in: PubMed
    Score: 0.007
  45. Louie SW, Ramirez LM, Krieg AM, Maliszewski CR, Bishop GA. Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone. J Immunol. 1993 Jan 15; 150(2):399-406.
    View in: PubMed
    Score: 0.005
  46. Klinman DM, Krieg A, Conover J, Ussery MA, Black PL. Effect of cyclophosphamide, total body irradiation, and zidovudine on retrovirus proliferation and disease progression in murine AIDS. AIDS Res Hum Retroviruses. 1992 Jan; 8(1):101-6.
    View in: PubMed
    Score: 0.005
  47. Steinberg AD, Krieg AM, Gourley MF, Klinman DM. Theoretical and experimental approaches to generalized autoimmunity. Immunol Rev. 1990 Dec; 118:129-63.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.