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Connection

Sudhir Agrawal to CpG Islands

This is a "connection" page, showing publications Sudhir Agrawal has written about CpG Islands.
Connection Strength

2.540
  1. Yu D, Wang D, Zhu FG, Bhagat L, Dai M, Kandimalla ER, Agrawal S. Modifications incorporated in CpG motifs of oligodeoxynucleotides lead to antagonist activity of toll-like receptors 7 and 9. J Med Chem. 2009 Aug 27; 52(16):5108-14.
    View in: PubMed
    Score: 0.306
  2. Yu D, Putta MR, Bhagat L, Li Y, Zhu F, Wang D, Tang JX, Kandimalla ER, Agrawal S. Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs. J Med Chem. 2007 Dec 13; 50(25):6411-8.
    View in: PubMed
    Score: 0.270
  3. Agrawal S, Kandimalla ER. Modulation of Toll-like Receptor 9 Responses through Synthetic Immunostimulatory Motifs of DNA. Ann N Y Acad Sci. 2003 Dec; 1002:30-42.
    View in: PubMed
    Score: 0.206
  4. Cong YP, Song SS, Bhagat L, Pandey RK, Yu D, Kandimalla ER, Agrawal S. Self-stabilized CpG DNAs optimally activate human B cells and plasmacytoid dendritic cells. Biochem Biophys Res Commun. 2003 Oct 31; 310(4):1133-9.
    View in: PubMed
    Score: 0.204
  5. Kandimalla ER, Bhagat L, Cong YP, Pandey RK, Yu D, Zhao Q, Agrawal S. Secondary structures in CpG oligonucleotides affect immunostimulatory activity. Biochem Biophys Res Commun. 2003 Jul 11; 306(4):948-53.
    View in: PubMed
    Score: 0.200
  6. Kandimalla ER, Agrawal S. Chemistry of CpG DNA. Curr Protoc Nucleic Acid Chem. 2003 May; Chapter 4:Unit 4.16.
    View in: PubMed
    Score: 0.198
  7. Yu D, Kandimalla ER, Zhao Q, Bhagat L, Cong Y, Agrawal S. Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNA. Bioorg Med Chem. 2003 Feb 06; 11(3):459-64.
    View in: PubMed
    Score: 0.194
  8. Yu D, Kandimalla ER, Cong Y, Tang J, Tang JY, Zhao Q, Agrawal S. Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: role of nucleosides in the flanking sequences. J Med Chem. 2002 Sep 26; 45(20):4540-8.
    View in: PubMed
    Score: 0.190
  9. Yu D, Kandimalla ER, Zhao Q, Cong Y, Agrawal S. Immunostimulatory properties of phosphorothioate CpG DNA containing both 3'-5'- and 2'-5'-internucleotide linkages. Nucleic Acids Res. 2002 Apr 01; 30(7):1613-9.
    View in: PubMed
    Score: 0.183
  10. Agrawal S, Kandimalla ER. Medicinal chemistry and therapeutic potential of CpG DNA. Trends Mol Med. 2002 Mar; 8(3):114-21.
    View in: PubMed
    Score: 0.182
  11. Yu D, Putta MR, Bhagat L, Dai M, Wang D, Trombino AF, Sullivan T, Kandimalla ER, Agrawal S. Impact of secondary structure of toll-like receptor 9 agonists on interferon alpha induction. Antimicrob Agents Chemother. 2008 Dec; 52(12):4320-5.
    View in: PubMed
    Score: 0.072
  12. Putta MR, Zhu F, Li Y, Bhagat L, Cong Y, Kandimalla ER, Agrawal S. Novel oligodeoxynucleotide agonists of TLR9 containing N3-Me-dC or N1-Me-dG modifications. Nucleic Acids Res. 2006; 34(11):3231-8.
    View in: PubMed
    Score: 0.061
  13. Li Y, Kandimalla ER, Yu D, Agrawal S. Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in mice. Int Immunopharmacol. 2005 Jun; 5(6):981-91.
    View in: PubMed
    Score: 0.057
  14. Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S. Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6925-30.
    View in: PubMed
    Score: 0.057
  15. Wang D, Li Y, Yu D, Song SS, Kandimalla ER, Agrawal S. Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs. Int J Oncol. 2004 Apr; 24(4):901-8.
    View in: PubMed
    Score: 0.053
  16. Yu D, Zhu FG, Bhagat L, Wang H, Kandimalla ER, Zhang R, Agrawal S. Potent CpG oligonucleotides containing phosphodiester linkages: in vitro and in vivo immunostimulatory properties. Biochem Biophys Res Commun. 2002 Sep 13; 297(1):83-90.
    View in: PubMed
    Score: 0.047
  17. Kandimalla ER, Yu D, Agrawal S. Towards optimal design of second-generation immunomodulatory oligonucleotides. Curr Opin Mol Ther. 2002 Apr; 4(2):122-9.
    View in: PubMed
    Score: 0.046
  18. Bjersing JL, Tarkowski A, Kandimalla ER, Karlsson H, Agrawal S, Collins LV. Impact of site-specific nucleobase deletions on the arthritogenicity of DNA. Inflammation. 2004 Jun; 28(3):159-68.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.