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Johanna Seddon to Aged

This is a "connection" page, showing publications Johanna Seddon has written about Aged.
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2.432
  1. Seddon JM, De D, Grunenkovaite L, Ferrara D. Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications. Invest Ophthalmol Vis Sci. 2024 Dec 02; 65(14):31.
    View in: PubMed
    Score: 0.080
  2. Seddon JM, De D, Rosner B. The role of nutritional factors in transitioning between early, mid, and late stages of age-related macular degeneration: prospective longitudinal analysis. Am J Clin Nutr. 2024 Dec; 120(6):1387-1398.
    View in: PubMed
    Score: 0.078
  3. Seddon JM, Widjajahakim R, Rosner B. Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2020 12 01; 61(14):32.
    View in: PubMed
    Score: 0.060
  4. Merle BMJ, Rosner B, Seddon JM. Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size. Invest Ophthalmol Vis Sci. 2020 05 11; 61(5):17.
    View in: PubMed
    Score: 0.058
  5. Lutty GA, McLeod DS, Bhutto IA, Edwards MM, Seddon JM. Choriocapillaris dropout in early age-related macular degeneration. Exp Eye Res. 2020 03; 192:107939.
    View in: PubMed
    Score: 0.057
  6. Seddon JM, Dossett JP, Widjajahakim R, Rosner B. Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2019 10 01; 60(13):4469-4478.
    View in: PubMed
    Score: 0.056
  7. Seddon JM, Rosner B. Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals. Am J Ophthalmol. 2019 02; 198:223-261.
    View in: PubMed
    Score: 0.052
  8. Merle BMJ, Silver RE, Rosner B, Seddon JM. Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017 09 01; 58(11):4569-4578.
    View in: PubMed
    Score: 0.048
  9. Ferrara D, Silver RE, Louzada RN, Novais EA, Collins GK, Seddon JM. Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2017 07 01; 58(9):3519-3529.
    View in: PubMed
    Score: 0.048
  10. Seddon JM, McLeod DS, Bhutto IA, Villalonga MB, Silver RE, Wenick AS, Edwards MM, Lutty GA. Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration. JAMA Ophthalmol. 2016 Nov 01; 134(11):1272-1280.
    View in: PubMed
    Score: 0.046
  11. Lane M, Ferrara D, Louzada RN, Fujimoto JG, Seddon JM. Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report. Ophthalmic Surg Lasers Imaging Retina. 2016 08 01; 47(8):778-81.
    View in: PubMed
    Score: 0.045
  12. Seddon JM, Silver RE, Rosner B. Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis. Br J Ophthalmol. 2016 Dec; 100(12):1731-1737.
    View in: PubMed
    Score: 0.045
  13. Merle BM, Silver RE, Rosner B, Seddon JM. Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study. Am J Clin Nutr. 2016 Apr; 103(4):1135-44.
    View in: PubMed
    Score: 0.044
  14. Shah AR, Williams S, Baumal CR, Rosner B, Duker JS, Seddon JM. Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration. Am J Ophthalmol. 2016 Mar; 163:154-166.e8.
    View in: PubMed
    Score: 0.043
  15. Merle BM, Silver RE, Rosner B, Seddon JM. Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study. Am J Clin Nutr. 2015 Nov; 102(5):1196-206.
    View in: PubMed
    Score: 0.042
  16. Ferrara D, Seddon JM. Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration. JAMA Ophthalmol. 2015 Jul; 133(7):785-91.
    View in: PubMed
    Score: 0.041
  17. Seddon JM, Silver RE, Kwong M, Rosner B. Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2192-202.
    View in: PubMed
    Score: 0.041
  18. Seddon JM, Reynolds R, Yu Y, Rosner B. Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration. PLoS One. 2014; 9(1):e87047.
    View in: PubMed
    Score: 0.038
  19. Seddon JM, Reynolds R, Yu Y, Rosner B. Validation of a prediction algorithm for progression to advanced macular degeneration subtypes. JAMA Ophthalmol. 2013 Apr; 131(4):448-55.
    View in: PubMed
    Score: 0.035
  20. Reynolds R, Rosner B, Seddon JM. Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy. Ophthalmology. 2013 May; 120(5):1020-8.
    View in: PubMed
    Score: 0.035
  21. Ioannidis JP, Yu Y, Seddon JM. Correction of phenotype misclassification based on high-discrimination genetic predictive risk models. Epidemiology. 2012 Nov; 23(6):902-9.
    View in: PubMed
    Score: 0.034
  22. Leveziel N, Yu Y, Reynolds R, Tai A, Meng W, Caillaux V, Calvas P, Rosner B, Malecaze F, Souied EH, Seddon JM. Genetic factors for choroidal neovascularization associated with high myopia. Invest Ophthalmol Vis Sci. 2012 Jul 27; 53(8):5004-9.
    View in: PubMed
    Score: 0.034
  23. Yu Y, Reynolds R, Rosner B, Daly MJ, Seddon JM. Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1548-56.
    View in: PubMed
    Score: 0.033
  24. Raychaudhuri S, Iartchouk O, Chin K, Tan PL, Tai AK, Ripke S, Gowrisankar S, Vemuri S, Montgomery K, Yu Y, Reynolds R, Zack DJ, Campochiaro B, Campochiaro P, Katsanis N, Daly MJ, Seddon JM. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. Nat Genet. 2011 Oct 23; 43(12):1232-6.
    View in: PubMed
    Score: 0.032
  25. Seddon JM, Reynolds R, Yu Y, Daly MJ, Rosner B. Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors. Ophthalmology. 2011 Nov; 118(11):2203-11.
    View in: PubMed
    Score: 0.032
  26. Peter I, Huggins GS, Ordovas JM, Haan M, Seddon JM. Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study. Am J Ophthalmol. 2011 Dec; 152(6):1005-1013.e1.
    View in: PubMed
    Score: 0.032
  27. Yu Y, Reynolds R, Fagerness J, Rosner B, Daly MJ, Seddon JM. Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011 Jun 28; 52(7):4663-70.
    View in: PubMed
    Score: 0.031
  28. Wise LA, Rosenberg L, Radin RG, Mattox C, Yang EB, Palmer JR, Seddon JM. A prospective study of diabetes, lifestyle factors, and glaucoma among African-American women. Ann Epidemiol. 2011 Jun; 21(6):430-9.
    View in: PubMed
    Score: 0.031
  29. Weiner DE, Tighiouart H, Reynolds R, Seddon JM. Kidney function, albuminuria and age-related macular degeneration in NHANES III. Nephrol Dial Transplant. 2011 Oct; 26(10):3159-65.
    View in: PubMed
    Score: 0.031
  30. Sobrin L, Reynolds R, Yu Y, Fagerness J, Leveziel N, Bernstein PS, Souied EH, Daly MJ, Seddon JM. ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration. Am J Ophthalmol. 2011 Feb; 151(2):345-52.e3.
    View in: PubMed
    Score: 0.030
  31. Seddon JM, Reynolds R, Rosner B. Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration. Mol Vis. 2010 Nov 17; 16:2412-24.
    View in: PubMed
    Score: 0.030
  32. Reynolds R, Rosner B, Seddon JM. Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration. Ophthalmology. 2010 Oct; 117(10):1989-95.
    View in: PubMed
    Score: 0.030
  33. Seddon JM, Gensler G, Rosner B. C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration. Ophthalmology. 2010 Aug; 117(8):1560-6.
    View in: PubMed
    Score: 0.029
  34. Reynolds R, Hartnett ME, Atkinson JP, Giclas PC, Rosner B, Seddon JM. Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes. Invest Ophthalmol Vis Sci. 2009 Dec; 50(12):5818-27.
    View in: PubMed
    Score: 0.028
  35. Seddon JM, Reynolds R, Maller J, Fagerness JA, Daly MJ, Rosner B. Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest Ophthalmol Vis Sci. 2009 May; 50(5):2044-53.
    View in: PubMed
    Score: 0.026
  36. Seddon JM, Reynolds R, Rosner B. Peripheral retinal drusen and reticular pigment: association with CFHY402H and CFHrs1410996 genotypes in family and twin studies. Invest Ophthalmol Vis Sci. 2009 Feb; 50(2):586-91.
    View in: PubMed
    Score: 0.026
  37. Fagerness JA, Maller JB, Neale BM, Reynolds RC, Daly MJ, Seddon JM. Variation near complement factor I is associated with risk of advanced AMD. Eur J Hum Genet. 2009 Jan; 17(1):100-4.
    View in: PubMed
    Score: 0.026
  38. Klein ML, Francis PJ, Rosner B, Reynolds R, Hamon SC, Schultz DW, Ott J, Seddon JM. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology. 2008 Jun; 115(6):1019-25.
    View in: PubMed
    Score: 0.025
  39. Seddon JM, Francis PJ, George S, Schultz DW, Rosner B, Klein ML. Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA. 2007 Apr 25; 297(16):1793-800.
    View in: PubMed
    Score: 0.024
  40. Francis PJ, George S, Schultz DW, Rosner B, Hamon S, Ott J, Weleber RG, Klein ML, Seddon JM. The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered. 2007; 63(3-4):212-8.
    View in: PubMed
    Score: 0.023
  41. Maller J, George S, Purcell S, Fagerness J, Altshuler D, Daly MJ, Seddon JM. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet. 2006 Sep; 38(9):1055-9.
    View in: PubMed
    Score: 0.022
  42. Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol. 2006 Jul; 124(7):995-1001.
    View in: PubMed
    Score: 0.022
  43. Seddon JM, George S, Rosner B, Klein ML. CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered. 2006; 61(3):157-65.
    View in: PubMed
    Score: 0.022
  44. Seddon JM, Sharma S, Adelman RA. Evaluation of the clinical age-related maculopathy staging system. Ophthalmology. 2006 Feb; 113(2):260-6.
    View in: PubMed
    Score: 0.022
  45. Seddon JM, Gensler G, Klein ML, Milton RC. Evaluation of plasma homocysteine and risk of age-related macular degeneration. Am J Ophthalmol. 2006 Jan; 141(1):201-3.
    View in: PubMed
    Score: 0.021
  46. Seddon JM, George S, Rosner B, Rifai N. Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch Ophthalmol. 2005 Jun; 123(6):774-82.
    View in: PubMed
    Score: 0.021
  47. Seddon JM, Cote J, Page WF, Aggen SH, Neale MC. The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences. Arch Ophthalmol. 2005 Mar; 123(3):321-7.
    View in: PubMed
    Score: 0.020
  48. Seddon JM, Gensler G, Milton RC, Klein ML, Rifai N. Association between C-reactive protein and age-related macular degeneration. JAMA. 2004 Feb 11; 291(6):704-10.
    View in: PubMed
    Score: 0.019
  49. Seddon JM, Chen CA. The epidemiology of age-related macular degeneration. Int Ophthalmol Clin. 2004; 44(4):17-39.
    View in: PubMed
    Score: 0.019
  50. Seddon JM, Cote J, Rosner B. Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol. 2003 Dec; 121(12):1728-37.
    View in: PubMed
    Score: 0.019
  51. Seddon JM, Sharma S, Chong S, Hutchinson A, Allikmets R, Adelman RA. Phenotype and genotype correlations in two best families. Ophthalmology. 2003 Sep; 110(9):1724-31.
    View in: PubMed
    Score: 0.018
  52. Seddon JM, Cote J, Davis N, Rosner B. Progression of age-related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio. Arch Ophthalmol. 2003 Jun; 121(6):785-92.
    View in: PubMed
    Score: 0.018
  53. Snow KK, Cote J, Yang W, Davis NJ, Seddon JM. Association between reproductive and hormonal factors and age-related maculopathy in postmenopausal women. Am J Ophthalmol. 2002 Dec; 134(6):842-8.
    View in: PubMed
    Score: 0.017
  54. Bernstein PS, Leppert M, Singh N, Dean M, Lewis RA, Lupski JR, Allikmets R, Seddon JM. Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings. Invest Ophthalmol Vis Sci. 2002 Feb; 43(2):466-73.
    View in: PubMed
    Score: 0.016
  55. Seddon JM, Afshari MA, Sharma S, Bernstein PS, Chong S, Hutchinson A, Petrukhin K, Allikmets R. Assessment of mutations in the Best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull's-eye maculopathy. Ophthalmology. 2001 Nov; 108(11):2060-7.
    View in: PubMed
    Score: 0.016
  56. Seddon JM, Rosner B, Sperduto RD, Yannuzzi L, Haller JA, Blair NP, Willett W. Dietary fat and risk for advanced age-related macular degeneration. Arch Ophthalmol. 2001 Aug; 119(8):1191-9.
    View in: PubMed
    Score: 0.016
  57. Kleinerman RA, Schonfeld SJ, Abramson DH, Francis JH, Seddon JM, Morton LM, Tucker MA. Increased Risk of Skin Cancer in 1,851 Long-Term Retinoblastoma Survivors. J Invest Dermatol. 2021 12; 141(12):2849-2857.e3.
    View in: PubMed
    Score: 0.016
  58. McMahon O, Hallam TM, Patel S, Harris CL, Menny A, Zelek WM, Widjajahakim R, Java A, Cox TE, Tzoumas N, Steel DHW, Shuttleworth VG, Smith-Jackson K, Brocklebank V, Griffiths H, Cree AJ, Atkinson JP, Lotery AJ, Bubeck D, Morgan BP, Marchbank KJ, Seddon JM, Kavanagh D. The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. Hum Mol Genet. 2021 06 17; 30(13):1188-1199.
    View in: PubMed
    Score: 0.016
  59. McCabe P, Nason F, Demers Turco P, Friedman D, Seddon JM. Evaluating the effectiveness of a vision rehabilitation intervention using an objective and subjective measure of functional performance. Ophthalmic Epidemiol. 2000 Dec; 7(4):259-70.
    View in: PubMed
    Score: 0.015
  60. Snow KK, Seddon JM. Age-related eye diseases: impact of hormone replacement therapy, and reproductive and other risk factors. Int J Fertil Womens Med. 2000 Sep-Oct; 45(5):301-13.
    View in: PubMed
    Score: 0.015
  61. Cho E, Hankinson SE, Willett WC, Stampfer MJ, Spiegelman D, Speizer FE, Rimm EB, Seddon JM. Prospective study of alcohol consumption and the risk of age-related macular degeneration. Arch Ophthalmol. 2000 May; 118(5):681-8.
    View in: PubMed
    Score: 0.014
  62. Mangione CM, Gutierrez PR, Lowe G, Orav EJ, Seddon JM. Influence of age-related maculopathy on visual functioning and health-related quality of life. Am J Ophthalmol. 1999 Jul; 128(1):45-53.
    View in: PubMed
    Score: 0.014
  63. De la Paz MA, Pericak-Vance MA, Haines JL, Seddon JM. Phenotypic heterogeneity in families with age-related macular degeneration. Am J Ophthalmol. 1997 Sep; 124(3):331-43.
    View in: PubMed
    Score: 0.012
  64. De La Paz MA, Pericak-Vance MA, Lennon F, Haines JL, Seddon JM. Exclusion of TIMP3 as a candidate locus in age-related macular degeneration. Invest Ophthalmol Vis Sci. 1997 May; 38(6):1060-5.
    View in: PubMed
    Score: 0.012
  65. Seddon JM, Ajani UA, Mitchell BD. Familial aggregation of age-related maculopathy. Am J Ophthalmol. 1997 Feb; 123(2):199-206.
    View in: PubMed
    Score: 0.012
  66. McLeod DS, Bhutto I, Edwards MM, Silver RE, Seddon JM, Lutty GA. Distribution and Quantification of Choroidal Macrophages in Human Eyes With Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2016 Nov 01; 57(14):5843-5855.
    View in: PubMed
    Score: 0.011
  67. Bhutto IA, McLeod DS, Jing T, Sunness JS, Seddon JM, Lutty GA. Increased choroidal mast cells and their degranulation in age-related macular degeneration. Br J Ophthalmol. 2016 May; 100(5):720-6.
    View in: PubMed
    Score: 0.011
  68. de Carlo TE, Adhi M, Salz DA, Joseph T, Waheed NK, Seddon JM, Duker JS, Reichel E. Analysis of Choroidal and Retinal Vasculature in Inherited Retinal Degenerations Using Optical Coherence Tomography Angiography. Ophthalmic Surg Lasers Imaging Retina. 2016 Feb; 47(2):120-7.
    View in: PubMed
    Score: 0.011
  69. Bernstein PS, Seddon JM. Decision-making in the treatment of subfoveal neovascularization in age-related macular degeneration. An analysis from the patient's perspective. Retina. 1996; 16(2):112-6.
    View in: PubMed
    Score: 0.011
  70. Hiller R, Seigel D, Sperduto RD, Blair N, Burton TC, Farber MD, Gragoudas ES, Gunter EW, Haller J, Seddon JM, et al. Serum zinc and serum lipid profiles in 778 adults. Ann Epidemiol. 1995 Nov; 5(6):490-6.
    View in: PubMed
    Score: 0.011
  71. Triebwasser MP, Roberson ED, Yu Y, Schramm EC, Wagner EK, Raychaudhuri S, Seddon JM, Atkinson JP. Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6873-8.
    View in: PubMed
    Score: 0.011
  72. Edwards MM, McLeod DS, Bhutto IA, Villalonga MB, Seddon JM, Lutty GA. Idiopathic preretinal glia in aging and age-related macular degeneration. Exp Eye Res. 2016 09; 150:44-61.
    View in: PubMed
    Score: 0.010
  73. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. JAMA. 1994 Nov 09; 272(18):1413-20.
    View in: PubMed
    Score: 0.010
  74. Seddon JM, Christen WG, Manson JE, LaMotte FS, Glynn RJ, Buring JE, Hennekens CH. The use of vitamin supplements and the risk of cataract among US male physicians. Am J Public Health. 1994 May; 84(5):788-92.
    View in: PubMed
    Score: 0.010
  75. Ajani UA, Willett WC, Seddon JM. Reproducibility of a food frequency questionnaire for use in ocular research. Eye Disease Case-Control Study Group. Invest Ophthalmol Vis Sci. 1994 May; 35(6):2725-33.
    View in: PubMed
    Score: 0.010
  76. Gragoudas ES, Egan KM, Saornil MA, Walsh SM, Albert DM, Seddon JM. The time course of irradiation changes in proton beam-treated uveal melanomas. Ophthalmology. 1993 Oct; 100(10):1555-9; discussion 1560.
    View in: PubMed
    Score: 0.009
  77. Christen WG, Seddon JM. Cigarette smoking and cataract. Am J Prev Med. 1993 Jan-Feb; 9(1):65-6.
    View in: PubMed
    Score: 0.009
  78. Seddon JM, Egan KM, Zhang Y, Gelles EJ, Glynn RJ, Tucker CA, Gragoudas ES. Evaluation of skin microtopography as a measure of ultraviolet exposure. Invest Ophthalmol Vis Sci. 1992 May; 33(6):1903-8.
    View in: PubMed
    Score: 0.008
  79. Stanton CM, Yates JR, den Hollander AI, Seddon JM, Swaroop A, Stambolian D, Fauser S, Hoyng C, Yu Y, Atsuhiro K, Branham K, Othman M, Chen W, Kortvely E, Chalmers K, Hayward C, Moore AT, Dhillon B, Ueffing M, Wright AF. Complement factor D in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2011 Nov 11; 52(12):8828-34.
    View in: PubMed
    Score: 0.008
  80. McKay GJ, Patterson CC, Chakravarthy U, Dasari S, Klaver CC, Vingerling JR, Ho L, de Jong PT, Fletcher AE, Young IS, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Hingorani AD, Sofat R, Dean M, Sawitzke J, Seddon JM, Peter I, Webster AR, Moore AT, Yates JR, Cipriani V, Fritsche LG, Weber BH, Keilhauer CN, Lotery AJ, Ennis S, Klein ML, Francis PJ, Stambolian D, Orlin A, Gorin MB, Weeks DE, Kuo CL, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Wright AF, Hayward C, Baird PN, Guymer RH, Attia J, Thakkinstian A, Silvestri G. Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat. 2011 Dec; 32(12):1407-16.
    View in: PubMed
    Score: 0.008
  81. McKay GJ, Silvestri G, Chakravarthy U, Dasari S, Fritsche LG, Weber BH, Keilhauer CN, Klein ML, Francis PJ, Klaver CC, Vingerling JR, Ho L, De Jong PT, Dean M, Sawitzke J, Baird PN, Guymer RH, Stambolian D, Orlin A, Seddon JM, Peter I, Wright AF, Hayward C, Lotery AJ, Ennis S, Gorin MB, Weeks DE, Kuo CL, Hingorani AD, Sofat R, Cipriani V, Swaroop A, Othman M, Kanda A, Chen W, Abecasis GR, Yates JR, Webster AR, Moore AT, Seland JH, Rahu M, Soubrane G, Tomazzoli L, Topouzis F, Vioque J, Young IS, Fletcher AE, Patterson CC. Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol. 2011 Jun 15; 173(12):1357-64.
    View in: PubMed
    Score: 0.008
  82. Seddon JM, Christen WG, Manson JE, Buring JE, Sperduto RD, Hennekens CH. Low-dose aspirin and risks of cataract in a randomized trial of US physicians. Arch Ophthalmol. 1991 Feb; 109(2):252-5.
    View in: PubMed
    Score: 0.008
  83. Seddon JM, Gragoudas ES, Glynn RJ, Egan KM, Albert DM, Blitzer PH. Host factors, UV radiation, and risk of uveal melanoma. A case-control study. Arch Ophthalmol. 1990 Sep; 108(9):1274-80.
    View in: PubMed
    Score: 0.007
  84. Seddon JM, Gragoudas ES, Egan KM, Glynn RJ, Howard S, Fante RG, Albert DM. Relative survival rates after alternative therapies for uveal melanoma. Ophthalmology. 1990 Jun; 97(6):769-77.
    View in: PubMed
    Score: 0.007
  85. Jun JJ, Duker JS, Baumal CR, McCabe F, Reichel E, Rogers AH, Seddon JM, Tolentino FI. Cystoid macular edema without macular thickening: a retrospective optical coherence tomographic study. Retina. 2010 Jun; 30(6):917-23.
    View in: PubMed
    Score: 0.007
  86. Smith EV, Kolodny NH, Gragoudas ES, Egan KM, Finn S, D'Amico DJ, Seddon JM. An NMR blood test for uveal melanoma? Invest Ophthalmol Vis Sci. 1990 May; 31(5):993-7.
    View in: PubMed
    Score: 0.007
  87. Chodick G, Kleinerman RA, Stovall M, Abramson DH, Seddon JM, Smith SA, Tucker MA. Risk of cataract extraction among adult retinoblastoma survivors. Arch Ophthalmol. 2009 Nov; 127(11):1500-4.
    View in: PubMed
    Score: 0.007
  88. Zerbib J, Seddon JM, Richard F, Reynolds R, Leveziel N, Benlian P, Borel P, Feingold J, Munnich A, Soubrane G, Kaplan J, Rozet JM, Souied EH. rs5888 variant of SCARB1 gene is a possible susceptibility factor for age-related macular degeneration. PLoS One. 2009 Oct 05; 4(10):e7341.
    View in: PubMed
    Score: 0.007
  89. Yu CL, Tucker MA, Abramson DH, Furukawa K, Seddon JM, Stovall M, Fraumeni JF, Kleinerman RA. Cause-specific mortality in long-term survivors of retinoblastoma. J Natl Cancer Inst. 2009 Apr 15; 101(8):581-91.
    View in: PubMed
    Score: 0.007
  90. Friedman E, Ivry M, Ebert E, Glynn R, Gragoudas E, Seddon J. Increased scleral rigidity and age-related macular degeneration. Ophthalmology. 1989 Jan; 96(1):104-8.
    View in: PubMed
    Score: 0.007
  91. SanGiovanni JP, Chew EY, Agr?n E, Clemons TE, Ferris FL, Gensler G, Lindblad AS, Milton RC, Seddon JM, Klein R, Sperduto RD. The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol. 2008 Sep; 126(9):1274-9.
    View in: PubMed
    Score: 0.006
  92. Sheen V, Tucker MA, Abramson DH, Seddon JM, Kleinerman RA. Cancer screening practices of adult survivors of retinoblastoma at risk of second cancers. Cancer. 2008 Jul 15; 113(2):434-41.
    View in: PubMed
    Score: 0.006
  93. Maki J, Kusakul S, Morley K, Sanguansak T, Seddon J, Hartung L, Morley M. The effect of glasses on visual function following cataract surgery in a cataract camp. Br J Ophthalmol. 2008 Jul; 92(7):883-7.
    View in: PubMed
    Score: 0.006
  94. SanGiovanni JP, Chew EY, Clemons TE, Ferris FL, Gensler G, Lindblad AS, Milton RC, Seddon JM, Sperduto RD. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol. 2007 Sep; 125(9):1225-32.
    View in: PubMed
    Score: 0.006
  95. Seddon JM, Polivogianis L, Hsieh CC, Albert DM, Gamel JW, Gragoudas ES. Death from uveal melanoma. Number of epithelioid cells and inverse SD of nucleolar area as prognostic factors. Arch Ophthalmol. 1987 Jun; 105(6):801-6.
    View in: PubMed
    Score: 0.006
  96. SanGiovanni JP, Chew EY, Clemons TE, Davis MD, Ferris FL, Gensler GR, Kurinij N, Lindblad AS, Milton RC, Seddon JM, Sperduto RD. The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20. Arch Ophthalmol. 2007 May; 125(5):671-9.
    View in: PubMed
    Score: 0.006
  97. Klein R, Deng Y, Klein BE, Hyman L, Seddon J, Frank RN, Wallace RB, Hendrix SL, Kuppermann BD, Langer RD, Kuller L, Brunner R, Johnson KC, Thomas AM, Haan M. Cardiovascular disease, its risk factors and treatment, and age-related macular degeneration: Women's Health Initiative Sight Exam ancillary study. Am J Ophthalmol. 2007 Mar; 143(3):473-83.
    View in: PubMed
    Score: 0.006
  98. Kleinerman RA, Tucker MA, Abramson DH, Seddon JM, Tarone RE, Fraumeni JF. Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst. 2007 Jan 03; 99(1):24-31.
    View in: PubMed
    Score: 0.006
  99. Haan MN, Klein R, Klein BE, Deng Y, Blythe LK, Seddon JM, Musch DC, Kuller LH, Hyman LG, Wallace RB. Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam Study. Arch Ophthalmol. 2006 Jul; 124(7):988-92.
    View in: PubMed
    Score: 0.006
  100. Seddon JM, Gragoudas ES, Polivogianis L, Hsieh CC, Egan KM, Goitein M, Verhey L, Munzenrider J, Austin-Seymour M, Urie M, et al. Visual outcome after proton beam irradiation of uveal melanoma. Ophthalmology. 1986 May; 93(5):666-74.
    View in: PubMed
    Score: 0.005
  101. Clemons TE, Milton RC, Klein R, Seddon JM, Ferris FL. Risk factors for the incidence of Advanced Age-Related Macular Degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology. 2005 Apr; 112(4):533-9.
    View in: PubMed
    Score: 0.005
  102. Seddon JM, Gragoudas ES, Albert DM, Hsieh CC, Polivogianis L, Friedenberg GR. Comparison of survival rates for patients with uveal melanoma after treatment with proton beam irradiation or enucleation. Am J Ophthalmol. 1985 Mar 15; 99(3):282-90.
    View in: PubMed
    Score: 0.005
  103. Austin-Seymour M, Munzenrider JE, Goitein M, Gentry R, Gragoudas E, Koehler AM, McNulty P, Osborne E, Ryugo DK, Seddon J, et al. Progress in low-LET heavy particle therapy: intracranial and paracranial tumors and uveal melanomas. Radiat Res Suppl. 1985; 8:S219-26.
    View in: PubMed
    Score: 0.005
  104. Cho E, Seddon JM, Rosner B, Willett WC, Hankinson SE. Prospective study of intake of fruits, vegetables, vitamins, and carotenoids and risk of age-related maculopathy. Arch Ophthalmol. 2004 Jun; 122(6):883-92.
    View in: PubMed
    Score: 0.005
  105. Lavin PT, Albert DM, Seddon JM. A deficit survival analysis to assess the natural history of uveal melanoma. J Chronic Dis. 1984; 37(6):481-7.
    View in: PubMed
    Score: 0.005
  106. Seddon JM, Gragoudas ES, Albert DM. Ciliary body and choroidal melanomas treated by proton beam irradiation. Histopathologic study of eyes. Arch Ophthalmol. 1983 Sep; 101(9):1402-8.
    View in: PubMed
    Score: 0.005
  107. Seddon JM, Schwartz B, Flowerdew G. Case-control study of ocular hypertension. Arch Ophthalmol. 1983 Jun; 101(6):891-4.
    View in: PubMed
    Score: 0.004
  108. Weintraub JM, Willett WC, Rosner B, Colditz GA, Seddon JM, Hankinson SE. A prospective study of the relationship between body mass index and cataract extraction among US women and men. Int J Obes Relat Metab Disord. 2002 Dec; 26(12):1588-95.
    View in: PubMed
    Score: 0.004
  109. Weintraub JM, Willett WC, Rosner B, Colditz GA, Seddon JM, Hankinson SE. Smoking cessation and risk of cataract extraction among US women and men. Am J Epidemiol. 2002 Jan 01; 155(1):72-9.
    View in: PubMed
    Score: 0.004
  110. Ayyagari R, Zhang K, Hutchinson A, Yu Z, Swaroop A, Kakuk LE, Seddon JM, Bernstein PS, Lewis RA, Tammur J, Yang Z, Li Y, Zhang H, Yashar BM, Liu J, Petrukhin K, Sieving PA, Allikmets R. Evaluation of the ELOVL4 gene in patients with age-related macular degeneration. Ophthalmic Genet. 2001 Dec; 22(4):233-9.
    View in: PubMed
    Score: 0.004
  111. Schwartz B, Seddon JM. Increased plasma cortisol levels in ocular hypertension. Arch Ophthalmol. 1981 Oct; 99(10):1791-4.
    View in: PubMed
    Score: 0.004
  112. Cho E, Stampfer MJ, Seddon JM, Hung S, Spiegelman D, Rimm EB, Willett WC, Hankinson SE. Prospective study of zinc intake and the risk of age-related macular degeneration. Ann Epidemiol. 2001 Jul; 11(5):328-36.
    View in: PubMed
    Score: 0.004
  113. Cho E, Hung S, Willett WC, Spiegelman D, Rimm EB, Seddon JM, Colditz GA, Hankinson SE. Prospective study of dietary fat and the risk of age-related macular degeneration. Am J Clin Nutr. 2001 Feb; 73(2):209-18.
    View in: PubMed
    Score: 0.004
  114. Li W, Judge H, Gragoudas ES, Seddon JM, Egan KM. Patterns of tumor initiation in choroidal melanoma. Cancer Res. 2000 Jul 15; 60(14):3757-60.
    View in: PubMed
    Score: 0.004
  115. Gragoudas ES, Lane AM, Regan S, Li W, Judge HE, Munzenrider JE, Seddon JM, Egan KM. A randomized controlled trial of varying radiation doses in the treatment of choroidal melanoma. Arch Ophthalmol. 2000 Jun; 118(6):773-8.
    View in: PubMed
    Score: 0.004
  116. Chasan-Taber L, Willett WC, Seddon JM, Stampfer MJ, Rosner B, Colditz GA, Speizer FE, Hankinson SE. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr. 1999 Oct; 70(4):509-16.
    View in: PubMed
    Score: 0.003
  117. Brown L, Rimm EB, Seddon JM, Giovannucci EL, Chasan-Taber L, Spiegelman D, Willett WC, Hankinson SE. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr. 1999 Oct; 70(4):517-24.
    View in: PubMed
    Score: 0.003
  118. Allikmets R, Seddon JM, Bernstein PS, Hutchinson A, Atkinson A, Sharma S, Gerrard B, Li W, Metzker ML, Wadelius C, Caskey CT, Dean M, Petrukhin K. Evaluation of the Best disease gene in patients with age-related macular degeneration and other maculopathies. Hum Genet. 1999 Jun; 104(6):449-53.
    View in: PubMed
    Score: 0.003
  119. Chew EY, Sperduto RD, Hiller R, Nowroozi L, Seigel D, Yanuzzi LA, Burton TC, Seddon JM, Gragoudas ES, Haller JA, Blair NP, Farber M. Clinical course of macular holes: the Eye Disease Case-Control Study. Arch Ophthalmol. 1999 Feb; 117(2):242-6.
    View in: PubMed
    Score: 0.003
  120. Sperduto RD, Hiller R, Chew E, Seigel D, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Seddon JM, Yannuzzi LA. Risk factors for hemiretinal vein occlusion: comparison with risk factors for central and branch retinal vein occlusion: the eye disease case-control study. Ophthalmology. 1998 May; 105(5):765-71.
    View in: PubMed
    Score: 0.003
  121. Allikmets R, Shroyer NF, Singh N, Seddon JM, Lewis RA, Bernstein PS, Peiffer A, Zabriskie NA, Li Y, Hutchinson A, Dean M, Lupski JR, Leppert M. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science. 1997 Sep 19; 277(5333):1805-7.
    View in: PubMed
    Score: 0.003
  122. Mangione CM, Orav EJ, Lawrence MG, Phillips RS, Seddon JM, Goldman L. Prediction of visual function after cataract surgery. A prospectively validated model. Arch Ophthalmol. 1995 Oct; 113(10):1305-11.
    View in: PubMed
    Score: 0.003
  123. Mangione CM, Phillips RS, Lawrence MG, Seddon JM, Orav EJ, Goldman L. Improved visual function and attenuation of declines in health-related quality of life after cataract extraction. Arch Ophthalmol. 1994 Nov; 112(11):1419-25.
    View in: PubMed
    Score: 0.002
  124. Christen WG, Glynn RJ, Seddon JM, Manson JE, Buring JE, Hennekens CH. Confirmation of self-reported cataract in the Physicians' Health Study. Ophthalmic Epidemiol. 1994 Jun; 1(2):85-91.
    View in: PubMed
    Score: 0.002
  125. Manson JE, Christen WG, Seddon JM, Glynn RJ, Hennekens CH. A prospective study of alcohol consumption and risk of cataract. Am J Prev Med. 1994 May-Jun; 10(3):156-61.
    View in: PubMed
    Score: 0.002
  126. Eng C, Li FP, Abramson DH, Ellsworth RM, Wong FL, Goldman MB, Seddon J, Tarbell N, Boice JD. Mortality from second tumors among long-term survivors of retinoblastoma. J Natl Cancer Inst. 1993 Jul 21; 85(14):1121-8.
    View in: PubMed
    Score: 0.002
  127. Mangione CM, Seddon JM, Cook EF, Krug JH, Sahagian CR, Campion EW, Glynn RJ. Correlates of cognitive function scores in elderly outpatients. J Am Geriatr Soc. 1993 May; 41(5):491-7.
    View in: PubMed
    Score: 0.002
  128. Hankinson SE, Seddon JM, Colditz GA, Stampfer MJ, Rosner B, Speizer FE, Willett WC. A prospective study of aspirin use and cataract extraction in women. Arch Ophthalmol. 1993 Apr; 111(4):503-8.
    View in: PubMed
    Score: 0.002
  129. Ajani UA, Seddon JM, Hsieh CC, Egan KM, Albert DM, Gragoudas ES. Occupation and risk of uveal melanoma. An exploratory study. Cancer. 1992 Dec 15; 70(12):2891-900.
    View in: PubMed
    Score: 0.002
  130. Mangione CM, Phillips RS, Seddon JM, Lawrence MG, Cook EF, Dailey R, Goldman L. Development of the 'Activities of Daily Vision Scale'. A measure of visual functional status. Med Care. 1992 Dec; 30(12):1111-26.
    View in: PubMed
    Score: 0.002
  131. Christen WG, Manson JE, Seddon JM, Glynn RJ, Buring JE, Rosner B, Hennekens CH. A prospective study of cigarette smoking and risk of cataract in men. JAMA. 1992 Aug 26; 268(8):989-93.
    View in: PubMed
    Score: 0.002
  132. Hankinson SE, Willett WC, Colditz GA, Seddon JM, Rosner B, Speizer FE, Stampfer MJ. A prospective study of cigarette smoking and risk of cataract surgery in women. JAMA. 1992 Aug 26; 268(8):994-8.
    View in: PubMed
    Score: 0.002
  133. Hankinson SE, Stampfer MJ, Seddon JM, Colditz GA, Rosner B, Speizer FE, Willett WC. Nutrient intake and cataract extraction in women: a prospective study. BMJ. 1992 Aug 08; 305(6849):335-9.
    View in: PubMed
    Score: 0.002
  134. Saornil MA, Egan KM, Gragoudas ES, Seddon JM, Walsh SM, Albert DM. Histopathology of proton beam-irradiated vs enucleated uveal melanomas. Arch Ophthalmol. 1992 Aug; 110(8):1112-8.
    View in: PubMed
    Score: 0.002
  135. Guyer DR, Mukai S, Egan KM, Seddon JM, Walsh SM, Gragoudas ES. Radiation maculopathy after proton beam irradiation for choroidal melanoma. Ophthalmology. 1992 Aug; 99(8):1278-85.
    View in: PubMed
    Score: 0.002
  136. Gragoudas ES, Egan KM, Seddon JM, Walsh SM, Munzenrider JE. Intraocular recurrence of uveal melanoma after proton beam irradiation. Ophthalmology. 1992 May; 99(5):760-6.
    View in: PubMed
    Score: 0.002
  137. Gragoudas ES, Egan KM, Arrigg PG, Seddon JM, Glynn RJ, Munzenrider JE. Cataract extraction after proton beam irradiation for malignant melanoma of the eye. Arch Ophthalmol. 1992 Apr; 110(4):475-9.
    View in: PubMed
    Score: 0.002
  138. Egan KM, Gragoudas ES, Seddon JM, Walsh SM. Smoking and the risk of early metastases from uveal melanoma. Ophthalmology. 1992 Apr; 99(4):537-41.
    View in: PubMed
    Score: 0.002
  139. Levin LA, Seddon JM, Topping T. Retinal pigment epithelial tears associated with trauma. Am J Ophthalmol. 1991 Oct 15; 112(4):396-400.
    View in: PubMed
    Score: 0.002
  140. Gragoudas ES, Egan KM, Seddon JM, Glynn RJ, Walsh SM, Finn SM, Munzenrider JE, Spar MD. Survival of patients with metastases from uveal melanoma. Ophthalmology. 1991 Mar; 98(3):383-9; discussion 390.
    View in: PubMed
    Score: 0.002
  141. Glynn RJ, Seddon JM, Krug JH, Sahagian CR, Chiavelli ME, Campion EW. Falls in elderly patients with glaucoma. Arch Ophthalmol. 1991 Feb; 109(2):205-10.
    View in: PubMed
    Score: 0.002
  142. Austin KL, Palmer JR, Seddon JM, Glynn RJ, Rosenberg L, Gragoudas ES, Kaufman DW, Shapiro S. Case-control study of idiopathic retinal detachment. Int J Epidemiol. 1990 Dec; 19(4):1045-50.
    View in: PubMed
    Score: 0.002
  143. Gragoudas ES, Seddon JM, Egan KM, Glynn RJ, Goitein M, Munzenrider J, Verhey L, Urie M, Koehler A. Metastasis from uveal melanoma after proton beam irradiation. Ophthalmology. 1988 Jul; 95(7):992-9.
    View in: PubMed
    Score: 0.002
  144. Adams KS, Abramson DH, Ellsworth RM, Haik BG, Bedford M, Packer S, Seddon J, Albert D, Polivogianis L. Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates. Br J Ophthalmol. 1988 Jul; 72(7):494-7.
    View in: PubMed
    Score: 0.002
  145. Glynn RJ, Seddon JM, Berlin BM. The incidence of eye injuries in New England adults. Arch Ophthalmol. 1988 Jun; 106(6):785-9.
    View in: PubMed
    Score: 0.002
  146. Bressler NM, Bressler SB, Seddon JM, Gragoudas ES, Jacobson LP. Drusen characteristics in patients with exudative versus non-exudative age-related macular degeneration. Retina. 1988; 8(2):109-14.
    View in: PubMed
    Score: 0.002
  147. terPenning BJ, Cheng HM, Barnett P, Seddon J, Sang D, Latina M, Aguayo J, Gonz?lez RG, Brady TJ. MR imaging of enucleated human eyes at 1.4 tesla. J Comput Assist Tomogr. 1986 Jul-Aug; 10(4):551-9.
    View in: PubMed
    Score: 0.001
  148. Gragoudas ES, Seddon J, Goitein M, Verhey L, Munzenrider J, Urie M, Suit HD, Blitzer P, Koehler A. Current results of proton beam irradiation of uveal melanomas. Ophthalmology. 1985 Feb; 92(2):284-91.
    View in: PubMed
    Score: 0.001
  149. Gragoudas ES, Goitein M, Seddon J, Verhey L, Munzenrider J, Urie M, Suit HD, Blitzer P, Johnson KN, Koehler A. Preliminary results of proton beam irradiation of macular and paramacular melanomas. Br J Ophthalmol. 1984 Jul; 68(7):479-85.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.