Nikolaus Grigorieff to Cryoelectron Microscopy
This is a "connection" page, showing publications Nikolaus Grigorieff has written about Cryoelectron Microscopy.
Connection Strength
11.576
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Elferich J, Kaminek M, Kong L, Odriozola A, Kukulski W, Zuber B, Grigorieff N. In situ high-resolution cryo-EM reconstructions from CEMOVIS. IUCrJ. 2025 Jul 01; 12(Pt 4):502-510.
Score: 0.836
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Zhang K, Cossio P, Rangan AV, Lucas BA, Grigorieff N. A new statistical metric for robust target detection in cryo-EM using 2D template matching. IUCrJ. 2025 Mar 01; 12(Pt 2):155-176.
Score: 0.817
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Lucas BA, Himes BA, Xue L, Grant T, Mahamid J, Grigorieff N. Locating macromolecular assemblies in cells by 2D template matching with cisTEM. Elife. 2021 06 11; 10.
Score: 0.631
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Grant T, Rohou A, Grigorieff N. cisTEM, user-friendly software for single-particle image processing. Elife. 2018 03 07; 7.
Score: 0.503
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Grigorieff N. Frealign: An Exploratory Tool for Single-Particle Cryo-EM. Methods Enzymol. 2016; 579:191-226.
Score: 0.446
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Schmidt M, Rohou A, Lasker K, Yadav JK, Schiene-Fischer C, F?ndrich M, Grigorieff N. Peptide dimer structure in an A?(1-42) fibril visualized with cryo-EM. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):11858-63.
Score: 0.423
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Grant T, Grigorieff N. Automatic estimation and correction of anisotropic magnification distortion in electron microscopes. J Struct Biol. 2015 Nov; 192(2):204-8.
Score: 0.421
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Grant T, Grigorieff N. Measuring the optimal exposure for single particle cryo-EM using a 2.6 ? reconstruction of rotavirus VP6. Elife. 2015 May 29; 4:e06980.
Score: 0.415
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Grigorieff N. Direct detection pays off for electron cryo-microscopy. Elife. 2013 Feb 19; 2:e00573.
Score: 0.355
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Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure. 2012 Nov 07; 20(11):1823-8.
Score: 0.345
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Brilot AF, Chen JZ, Cheng A, Pan J, Harrison SC, Potter CS, Carragher B, Henderson R, Grigorieff N. Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol. 2012 Mar; 177(3):630-7.
Score: 0.331
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Sindelar CV, Grigorieff N. An adaptation of the Wiener filter suitable for analyzing images of isolated single particles. J Struct Biol. 2011 Oct; 176(1):60-74.
Score: 0.317
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Grigorieff N, Harrison SC. Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Curr Opin Struct Biol. 2011 Apr; 21(2):265-73.
Score: 0.309
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Chen JZ, Settembre EC, Aoki ST, Zhang X, Bellamy AR, Dormitzer PR, Harrison SC, Grigorieff N. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10644-8.
Score: 0.274
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Zhang X, Settembre E, Xu C, Dormitzer PR, Bellamy R, Harrison SC, Grigorieff N. Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):1867-72.
Score: 0.250
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Chen JZ, Sachse C, Xu C, Mielke T, Spahn CM, Grigorieff N. A dose-rate effect in single-particle electron microscopy. J Struct Biol. 2008 Jan; 161(1):92-100.
Score: 0.244
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Sachse C, Chen JZ, Coureux PD, Stroupe ME, F?ndrich M, Grigorieff N. High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus. J Mol Biol. 2007 Aug 17; 371(3):812-35.
Score: 0.239
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Chen JZ, Grigorieff N. SIGNATURE: a single-particle selection system for molecular electron microscopy. J Struct Biol. 2007 Jan; 157(1):168-73.
Score: 0.223
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Dingeldein L, Silva-S?nchez D, Evans L, D'Imprima E, Grigorieff N, Covino R, Cossio P. Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference. Proc Natl Acad Sci U S A. 2025 Jun 10; 122(23):e2420158122.
Score: 0.208
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Woollard G, Zhou W, Thiede EH, Lin C, Grigorieff N, Cossio P, Dao Duc K, Hanson SM. InstaMap: instant-NGP for cryo-EM density maps. Acta Crystallogr D Struct Biol. 2025 Apr 01; 81(Pt 4):147-169.
Score: 0.205
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Elferich J, Kong L, Zottig X, Grigorieff N. CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples. Elife. 2024 Dec 20; 13.
Score: 0.201
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Jurica MS, Sousa D, Moore MJ, Grigorieff N. Three-dimensional structure of C complex spliceosomes by electron microscopy. Nat Struct Mol Biol. 2004 Mar; 11(3):265-9.
Score: 0.190
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Lucas BA, Himes BA, Grigorieff N. Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias. Elife. 2023 Nov 27; 12.
Score: 0.187
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Wolf M, Eberhart A, Glossmann H, Striessnig J, Grigorieff N. Visualization of the domain structure of an L-type Ca2+ channel using electron cryo-microscopy. J Mol Biol. 2003 Sep 05; 332(1):171-82.
Score: 0.184
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Lucas BA, Grigorieff N. Quantification of gallium cryo-FIB milling damage in biological lamellae. Proc Natl Acad Sci U S A. 2023 06 06; 120(23):e2301852120.
Score: 0.181
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Elferich J, Schiroli G, Scadden DT, Grigorieff N. Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections. Elife. 2022 11 16; 11.
Score: 0.174
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Lucas BA, Zhang K, Loerch S, Grigorieff N. In situ single particle classification reveals distinct 60S maturation intermediates in cells. Elife. 2022 08 25; 11.
Score: 0.172
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Abeyrathne PD, Grigorieff N. Expression, purification, and contaminant detection for structural studies of Ralstonia metallidurance ClC protein rm1. PLoS One. 2017; 12(7):e0180163.
Score: 0.120
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Loveland AB, Demo G, Grigorieff N, Korostelev AA. Ensemble cryo-EM elucidates the mechanism of translation fidelity. Nature. 2017 06 01; 546(7656):113-117.
Score: 0.119
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Liu Y, Pan J, Jenni S, Raymond DD, Caradonna T, Do KT, Schmidt AG, Harrison SC, Grigorieff N. CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface. J Mol Biol. 2017 06 16; 429(12):1829-1839.
Score: 0.119
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Rickgauer JP, Grigorieff N, Denk W. Single-protein detection in crowded molecular environments in cryo-EM images. Elife. 2017 05 03; 6.
Score: 0.119
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Schmidt A, Annamalai K, Schmidt M, Grigorieff N, F?ndrich M. Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):6200-5.
Score: 0.111
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Zhou A, Rohou A, Schep DG, Bason JV, Montgomery MG, Walker JE, Grigorieff N, Rubinstein JL. Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife. 2015 Oct 06; 4:e10180.
Score: 0.106
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Chiu PL, Li X, Li Z, Beckett B, Brilot AF, Grigorieff N, Agard DA, Cheng Y, Walz T. Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0. J Struct Biol. 2015 Nov; 192(2):163-73.
Score: 0.106
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Cheng Y, Grigorieff N, Penczek PA, Walz T. A primer to single-particle cryo-electron microscopy. Cell. 2015 Apr 23; 161(3):438-449.
Score: 0.103
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Brilot AF, Korostelev AA, Ermolenko DN, Grigorieff N. Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52):20994-9.
Score: 0.094
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Lyumkis D, Brilot AF, Theobald DL, Grigorieff N. Likelihood-based classification of cryo-EM images using FREALIGN. J Struct Biol. 2013 Sep; 183(3):377-388.
Score: 0.091
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Sindelar CV, Grigorieff N. Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter. J Struct Biol. 2012 Oct; 180(1):26-38.
Score: 0.084
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Henderson R, Chen S, Chen JZ, Grigorieff N, Passmore LA, Ciccarelli L, Rubinstein JL, Crowther RA, Stewart PL, Rosenthal PB. Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy. J Mol Biol. 2011 Nov 11; 413(5):1028-46.
Score: 0.080
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Li X, Grigorieff N, Cheng Y. GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors. J Struct Biol. 2010 Dec; 172(3):407-12.
Score: 0.074
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Schmidt M, Sachse C, Richter W, Xu C, F?ndrich M, Grigorieff N. Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures. Proc Natl Acad Sci U S A. 2009 Nov 24; 106(47):19813-8.
Score: 0.070
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Sachse C, F?ndrich M, Grigorieff N. Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy. Proc Natl Acad Sci U S A. 2008 May 27; 105(21):7462-6.
Score: 0.064
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Zeng X, Stahlberg H, Grigorieff N. A maximum likelihood approach to two-dimensional crystals. J Struct Biol. 2007 Dec; 160(3):362-74.
Score: 0.061
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Fotin A, Kirchhausen T, Grigorieff N, Harrison SC, Walz T, Cheng Y. Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. J Struct Biol. 2006 Dec; 156(3):453-60.
Score: 0.056
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Huang QJ, Kim R, Song K, Grigorieff N, Munro JB, Schiffer CA, Somasundaran M. Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryoelectron tomography. Proc Natl Acad Sci U S A. 2025 Apr 22; 122(16):e2426427122.
Score: 0.052
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Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature. 2004 Dec 02; 432(7017):573-9.
Score: 0.050
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Furst J, Sutton RB, Chen J, Brunger AT, Grigorieff N. Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution. EMBO J. 2003 Sep 01; 22(17):4365-74.
Score: 0.046
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Pitsawong W, P?dua RAP, Grant T, Hoemberger M, Otten R, Bradshaw N, Grigorieff N, Kern D. From primordial clocks to circadian oscillators. Nature. 2023 04; 616(7955):183-189.
Score: 0.045
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Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N, Ermolenko DN. mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding. Elife. 2020 05 19; 9.
Score: 0.037
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Syrjanen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. Structure and assembly of calcium homeostasis modulator proteins. Nat Struct Mol Biol. 2020 02; 27(2):150-159.
Score: 0.036
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Song K, Shang Z, Fu X, Lou X, Grigorieff N, Nicastro D. In situ structure determination at nanometer resolution using TYGRESS. Nat Methods. 2020 02; 17(2):201-208.
Score: 0.035
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Jung J, Grant T, Thomas DR, Diehnelt CW, Grigorieff N, Joshua-Tor L. High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):12828-12832.
Score: 0.034
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Liberta F, Loerch S, Rennegarbe M, Schierhorn A, Westermark P, Westermark GT, Hazenberg BPC, Grigorieff N, F?ndrich M, Schmidt M. Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids. Nat Commun. 2019 03 07; 10(1):1104.
Score: 0.034
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Zhang C, Cantara W, Jeon Y, Musier-Forsyth K, Grigorieff N, Lyumkis D. Analysis of discrete local variability and structural covariance in macromolecular assemblies using Cryo-EM and focused classification. Ultramicroscopy. 2019 08; 203:170-180.
Score: 0.033
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Bartesaghi A, Aguerrebere C, Falconieri V, Banerjee S, Earl LA, Zhu X, Grigorieff N, Milne JLS, Sapiro G, Wu X, Subramaniam S. Atomic Resolution Cryo-EM Structure of ?-Galactosidase. Structure. 2018 06 05; 26(6):848-856.e3.
Score: 0.032
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Close W, Neumann M, Schmidt A, Hora M, Annamalai K, Schmidt M, Reif B, Schmidt V, Grigorieff N, F?ndrich M. Physical basis of amyloid fibril polymorphism. Nat Commun. 2018 02 16; 9(1):699.
Score: 0.031
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Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev AA. Structure of RNA polymerase bound to ribosomal 30S subunit. Elife. 2017 10 13; 6.
Score: 0.031
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Liu Y, Pan J, Cai Y, Grigorieff N, Harrison SC, Chen B. Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer. J Virol. 2017 05 15; 91(10).
Score: 0.030
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Demo G, Svidritskiy E, Madireddy R, Diaz-Avalos R, Grant T, Grigorieff N, Sousa D, Korostelev AA. Mechanism of ribosome rescue by ArfA and RF2. Elife. 2017 03 16; 6.
Score: 0.029
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Oldham ML, Grigorieff N, Chen J. Structure of the transporter associated with antigen processing trapped by herpes simplex virus. Elife. 2016 12 09; 5.
Score: 0.029
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Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA. Ribosome?RelA structures reveal the mechanism of stringent response activation. Elife. 2016 07 19; 5.
Score: 0.028
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Laxmikanthan G, Xu C, Brilot AF, Warren D, Steele L, Seah N, Tong W, Grigorieff N, Landy A, Van Duyne GD. Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction. Elife. 2016 05 25; 5.
Score: 0.028
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Abeyrathne PD, Koh CS, Grant T, Grigorieff N, Korostelev AA. Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife. 2016 05 09; 5.
Score: 0.028
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Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature. 2016 06 02; 534(7605):63-8.
Score: 0.028
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Liang B, Li Z, Jenni S, Rahmeh AA, Morin BM, Grant T, Grigorieff N, Harrison SC, Whelan SPJ. Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy. Cell. 2015 Jul 16; 162(2):314-327.
Score: 0.026
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Svidritskiy E, Brilot AF, Koh CS, Grigorieff N, Korostelev AA. Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations. Structure. 2014 Aug 05; 22(8):1210-1218.
Score: 0.024
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Estrozi LF, Settembre EC, Goret G, McClain B, Zhang X, Chen JZ, Grigorieff N, Harrison SC. Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles. J Mol Biol. 2013 Jan 09; 425(1):124-32.
Score: 0.022
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Veesler D, Quispe J, Grigorieff N, Potter CS, Carragher B, Johnson JE. Maturation in action: CryoEM study of a viral capsid caught during expansion. Structure. 2012 Aug 08; 20(8):1384-90.
Score: 0.021
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Settembre EC, Chen JZ, Dormitzer PR, Grigorieff N, Harrison SC. Atomic model of an infectious rotavirus particle. EMBO J. 2011 Jan 19; 30(2):408-16.
Score: 0.019
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Alushin GM, Ramey VH, Pasqualato S, Ball DA, Grigorieff N, Musacchio A, Nogales E. The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature. 2010 Oct 14; 467(7317):805-10.
Score: 0.019
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Wolf M, Garcea RL, Grigorieff N, Harrison SC. Subunit interactions in bovine papillomavirus. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6298-303.
Score: 0.018
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Sachse C, Grigorieff N, F?ndrich M. Nanoscale flexibility parameters of Alzheimer amyloid fibrils determined by electron cryo-microscopy. Angew Chem Int Ed Engl. 2010 Feb 08; 49(7):1321-3.
Score: 0.018
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Xing Y, B?cking T, Wolf M, Grigorieff N, Kirchhausen T, Harrison SC. Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. EMBO J. 2010 Feb 03; 29(3):655-65.
Score: 0.018
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Meinhardt J, Sachse C, Hortschansky P, Grigorieff N, F?ndrich M. Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils. J Mol Biol. 2009 Feb 27; 386(3):869-77.
Score: 0.017
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Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 2004 Dec 02; 432(7017):649-53.
Score: 0.012
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Smith CJ, Grigorieff N, Pearse BM. Clathrin coats at 21 A resolution: a cellular assembly designed to recycle multiple membrane receptors. EMBO J. 1998 Sep 01; 17(17):4943-53.
Score: 0.008