Fiachra Humphries to Humans
This is a "connection" page, showing publications Fiachra Humphries has written about Humans.
Connection Strength
0.440
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Humphries F. Misfirin' pyrin. Sci Immunol. 2026 08 07; 11(122):eaei8902.
Score: 0.037
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Cahill S, Humphries F. Measurement and quantification of macrophage lytic cell death by kinetic microscopy. Methods Cell Biol. 2026; 206:109-122.
Score: 0.036
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Stine LB, Humphries F. Measurement of plasma membrane rupture via confocal microscopy. Methods Cell Biol. 2026; 205:47-62.
Score: 0.036
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Stine L, Cahill S, Humphries F. Interferons in human inborn errors of disease. mBio. 2025 08 13; 16(8):e0157025.
Score: 0.034
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Shmuel-Galia L, Jiang Z, Stine L, Cahill S, Ng SL, Wilson R, Kandasamy RK, Kurt-Jones EA, Ramanjulu JM, Bertin J, Kasparcova V, Pesiridis GS, Fitzgerald KA, Humphries F. Alternative cGAS signaling promotes herpes simplex encephalitis. Proc Natl Acad Sci U S A. 2025 Jun 03; 122(22):e2423873122.
Score: 0.034
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Cahill S, Humphries F. Inflammasomopathies: mechanisms and disease signatures. Trends Immunol. 2025 05; 46(5):372-385.
Score: 0.034
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Yang S, Humphries F. Emerging roles of ECSIT in immunity and tumorigenesis. Trends Cell Biol. 2025 May; 35(5):426-438.
Score: 0.032
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Stine L, Humphries F. Gasdermin D palmitoylation: to cleave or not to cleave? Trends Immunol. 2024 06; 45(6):403-405.
Score: 0.032
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Humphries F. cGAS-like receptors: back to the future. Trends Immunol. 2023 10; 44(10):760-762.
Score: 0.030
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Humphries F, Fitzgerald KA. Igniting the firestorm: The inflammasome in autoinflammatory syndromes. J Allergy Clin Immunol. 2021 12; 148(6):1470-1472.
Score: 0.026
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Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Succination inactivates gasdermin D and blocks pyroptosis. Science. 2020 09 25; 369(6511):1633-1637.
Score: 0.024
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Humphries F, Fitzgerald KA. Assembling the Inflammasome, Piece by Piece. J Immunol. 2019 09 01; 203(5):1093-1094.
Score: 0.023
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Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Mathur A, Allabaji A, Nellikkalaya S, Paul S, Vidadala SR, Sarkar SK, Rajendran M, Patil SN, Kalonia H, Hale J, Humphries F, Fitzgerald KA, Thompson PR. Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING Pathway. J Med Chem. 2026 Apr 09; 69(7):8561-8582.
Score: 0.009
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Golonka RM, Intravaia LE, Shaqra AM, Li Q, Chen Y, Humphries F, Kurt-Yilmaz N, Fitzgerald KA, Schiffer CA, Wang Y, Cavacini LA. Engineered IgA-Fc fusion protein with bioactive nanobody neutralizes SARS-CoV-2 variants with mucosal delivery potential. J Biol Chem. 2026 Mar; 302(3):111210.
Score: 0.009
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Singh A, Barasa L, DeOrsey L, O'Reilly MD, Choudhary S, Cahill SE, Rossetti T, Green RM, Humphries F, Thompson PR. Triazole-based STING inhibitors. Bioorg Med Chem. 2026 Jan 01; 132:118484.
Score: 0.009
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Yang Y, Wang Y, Wang Z, Yan H, Gong Y, Hu Y, Jiang Y, Wen S, Xu F, Wang B, Humphries F, Chen Y, Wang X, Yang S. ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis. Nat Cell Biol. 2024 Mar; 26(3):450-463.
Score: 0.008
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Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR. Development of LB244, an Irreversible STING Antagonist. J Am Chem Soc. 2023 09 20; 145(37):20273-20288.
Score: 0.008
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Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023 03 14; 120(11):e2219523120.
Score: 0.007
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Li Q, Humphries F, Girardin RC, Wallace A, Ejemel M, Amcheslavsky A, McMahon CT, Schiller ZA, Ma Z, Cruz J, Dupuis AP, Payne AF, Maryam A, Yilmaz NK, McDonough KA, Pierce BG, Schiffer CA, Kruse AC, Klempner MS, Cavacini LA, Fitzgerald KA, Wang Y. Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants. Front Immunol. 2022; 13:995412.
Score: 0.007
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Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8.
Score: 0.006