John Pezzuto to Humans
This is a "connection" page, showing publications John Pezzuto has written about Humans.
Connection Strength
1.035
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Pezzuto JM. Perspective: Are Grapes Worthy of the Moniker Superfood? J Agric Food Chem. 2025 Aug 06; 73(31):19262-19272.
Score: 0.037
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Shcherbakova N, Pesaturo KA, Pezzuto JM. High Total Failures of the North American Pharmacist Licensure Examination (NAPLEX) Warrant Monitoring of Professional Pharmacy Programs. Am J Pharm Educ. 2024 Jul; 88(7):100723.
Score: 0.034
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Shcherbakova N, Pezzuto JM. Monitoring of schools and colleges of pharmacy based on NAPLEX passage rate. Curr Pharm Teach Learn. 2023 10; 15(10):854-860.
Score: 0.032
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Dave A, Beyoglu D, Park EJ, Idle JR, Pezzuto JM. Influence of grape consumption on the human microbiome. Sci Rep. 2023 05 12; 13(1):7706.
Score: 0.032
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Park EJ, Sang-Ngern M, Chang LC, Pezzuto JM. Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4?-hydroxywithanolide E isolated from Physalis peruviana. Mol Nutr Food Res. 2016 06; 60(6):1482-500.
Score: 0.019
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Fatima N, Kondratyuk TP, Park EJ, Marler LE, Jadoon M, Qazi MA, Mehboob Mirza H, Khan I, Atiq N, Chang LC, Ahmed S, Pezzuto JM. Endophytic fungi associated with Taxus fuana (West Himalayan Yew) of Pakistan: potential bio-resources for cancer chemopreventive agents. Pharm Biol. 2016 Nov; 54(11):2547-2554.
Score: 0.019
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Cragg GM, Pezzuto JM. Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents. Med Princ Pract. 2016; 25 Suppl 2:41-59.
Score: 0.019
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Vang O, Pezzuto JM. Introduction to Resveratrol and Health: 3rd International Conference. Ann N Y Acad Sci. 2015 Aug; 1348(1):v-vi.
Score: 0.018
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Pezzuto JM, Ma CS. Academic pharmacy strikes Hawai'i. Part 2. Hawaii J Med Public Health. 2015 Mar; 74(3):120-8.
Score: 0.018
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Park EJ, Pezzuto JM. The pharmacology of resveratrol in animals and humans. Biochim Biophys Acta. 2015 Jun; 1852(6):1071-113.
Score: 0.018
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Pezzuto JM, Pezzuto MF. The Daniel K. Inouye College of Pharmacy scripts: Academic pharmacy strikes Hawai'i (part 1). Hawaii J Med Public Health. 2015 Jan; 74(1):33-6.
Score: 0.018
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Pezzuto JM, Kondratyuk TP, Ogas T. Resveratrol derivatives: a patent review (2009 - 2012). Expert Opin Ther Pat. 2013 Dec; 23(12):1529-46.
Score: 0.016
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Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. Eur J Med Chem. 2013 Oct; 68:412-21.
Score: 0.016
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Ogas T, Kondratyuk TP, Pezzuto JM. Resveratrol analogs: promising chemopreventive agents. Ann N Y Acad Sci. 2013 Jul; 1290:21-9.
Score: 0.016
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Park EJ, Pezzuto JM. Antioxidant marine products in cancer chemoprevention. Antioxid Redox Signal. 2013 Jul 10; 19(2):115-38.
Score: 0.016
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Mirza B, Kondratyuk TP, Park EJ, Burns BE, Marler LE, Pezzuto JM. Preliminary evaluation for cancer chemopreventive and cytotoxic potential of naturally growing ethnobotanically selected plants of Pakistan. Pharm Biol. 2013 Mar; 51(3):316-28.
Score: 0.015
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Park EJ, Pezzuto JM. Flavonoids in cancer prevention. Anticancer Agents Med Chem. 2012 Oct 01; 12(8):836-51.
Score: 0.015
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Sun D, Hurdle JG, Lee R, Lee R, Cushman M, Pezzuto JM. Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead. ChemMedChem. 2012 Sep; 7(9):1541-5.
Score: 0.015
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Kondratyuk TP, Park EJ, Yu R, Van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Mar Drugs. 2012 Feb; 10(2):451-464.
Score: 0.015
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Suh N, Pezzuto JM. Strawberry fields forever? Cancer Prev Res (Phila). 2012 Jan; 5(1):30-3.
Score: 0.014
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Park EJ, Kiselev E, Conda-Sheridan M, Cushman M, Pezzuto JM. Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells. J Nat Prod. 2012 Mar 23; 75(3):378-84.
Score: 0.014
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Lewandowski C, Pezzuto JM. Pharmaceutical Biology: a retrospective. Pharm Biol. 2012 Jan; 50(1):1-5.
Score: 0.014
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Kondratyuk TP, Park EJ, Marler LE, Ahn S, Yuan Y, Choi Y, Yu R, van Breemen RB, Sun B, Hoshino J, Cushman M, Jermihov KC, Mesecar AD, Grubbs CJ, Pezzuto JM. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Mol Nutr Food Res. 2011 Aug; 55(8):1249-65.
Score: 0.014
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Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-a-induced nuclear factor ?B activation and aromatase activity by capsaicin and its analog capsazepine. J Med Food. 2011 Nov; 14(11):1344-51.
Score: 0.014
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Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prev Res (Phila). 2011 Apr; 4(4):592-607.
Score: 0.014
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Pezzuto JM. The phenomenon of resveratrol: redefining the virtues of promiscuity. Ann N Y Acad Sci. 2011 Jan; 1215:123-30.
Score: 0.013
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Marler L, Conda-Sheridan M, Cinelli MA, Morrell AE, Cushman M, Chen L, Huang K, Van Breemen R, Pezzuto JM. Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives. Anticancer Res. 2010 Dec; 30(12):4873-82.
Score: 0.013
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Morais MC, Luqman S, Kondratyuk TP, Petronio MS, Regasini LO, Silva DH, Bolzani VS, Soares CP, Pezzuto JM. Suppression of TNF-a induced NF?B activity by gallic acid and its semi-synthetic esters: possible role in cancer chemoprevention. Nat Prod Res. 2010 Nov; 24(18):1758-65.
Score: 0.013
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Luqman S, Pezzuto JM. NFkappaB: a promising target for natural products in cancer chemoprevention. Phytother Res. 2010 Jul; 24(7):949-63.
Score: 0.013
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Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prev Res (Phila). 2010 Feb; 3(2):221-32.
Score: 0.013
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Pezzuto JM, Venkatasubramanian V, Hamad M, Morris KR. Unraveling the relationship between grapes and health. J Nutr. 2009 Sep; 139(9):1783S-7S.
Score: 0.012
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Asolkar RN, Freel KC, Jensen PR, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. J Nat Prod. 2009 Mar 27; 72(3):396-402.
Score: 0.012
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Cuendet M, Oteham CP, Maiti A, Craig BA, Cushman M, Moon RC, Pezzuto JM. Zapotin prevents mouse skin tumorigenesis during the stages of initiation and promotion. Anticancer Res. 2008 Nov-Dec; 28(6A):3705-9.
Score: 0.012
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Guilford JM, Pezzuto JM. Natural products as inhibitors of carcinogenesis. Expert Opin Investig Drugs. 2008 Sep; 17(9):1341-52.
Score: 0.011
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Pezzuto JM. Grapes and human health: a perspective. J Agric Food Chem. 2008 Aug 27; 56(16):6777-84.
Score: 0.011
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Francy-Guilford J, Pezzuto JM. Mechanisms of cancer chemopreventive agents: a perspective. Planta Med. 2008 Oct; 74(13):1644-50.
Score: 0.011
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Cuendet M, Mesecar AD, DeWitt DL, Pezzuto JM. An ELISA method to measure inhibition of the COX enzymes. Nat Protoc. 2006; 1(4):1915-21.
Score: 0.009
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Tamez PA, Lantvit D, Lim E, Pezzuto JM. Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum. J Ethnopharmacol. 2005 Apr 08; 98(1-2):137-42.
Score: 0.009
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Mi Q, Lantvit D, Reyes-Lim E, Chai H, Phifer SS, Wani MC, Wall ME, Tan GT, Cordell GA, Farnsworth NR, Kinghorn AD, Pezzuto JM. Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis. Anticancer Res. 2005 Mar-Apr; 25(2A):779-87.
Score: 0.009
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Pezzuto JM. Resveratrol: a whiff that induces a biologically specific tsunami. Cancer Biol Ther. 2004 Sep; 3(9):889-90.
Score: 0.009
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Kinghorn AD, Su BN, Jang DS, Chang LC, Lee D, Gu JQ, Carcache-Blanco EJ, Pawlus AD, Lee SK, Park EJ, Cuendet M, Gills JJ, Bhat K, Park HS, Mata-Greenwood E, Song LL, Jang M, Pezzuto JM. Natural inhibitors of carcinogenesis. Planta Med. 2004 Aug; 70(8):691-705.
Score: 0.009
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Cuendet M, Gills JJ, Pezzuto JM. Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation. Cancer Lett. 2004 Mar 31; 206(1):43-50.
Score: 0.008
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Cuendet M, Christov K, Lantvit DD, Deng Y, Hedayat S, Helson L, McChesney JD, Pezzuto JM. Multiple myeloma regression mediated by bruceantin. Clin Cancer Res. 2004 Feb 01; 10(3):1170-9.
Score: 0.008
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Cuendet M, Pezzuto JM. Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod. 2004 Feb; 67(2):269-72.
Score: 0.008
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Tan Y, Yu R, Pezzuto JM. Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation. Clin Cancer Res. 2003 Jul; 9(7):2866-75.
Score: 0.008
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Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov; 4(6):478-86.
Score: 0.008
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Verotta L, Guerrini M, El-Sebakhy NA, Assad AM, Toaima SM, Radwan MM, Luo YD, Pezzuto JM. Cycloartane and oleanane saponins from egyptian astragalus spp. as modulators of lymphocyte proliferation. Planta Med. 2002 Nov; 68(11):986-94.
Score: 0.008
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Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, Hollingshead MG, Mayo JG, Kinghorn AD, Pezzuto JM. Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay. Cancer Lett. 2002 Oct 08; 184(1):13-20.
Score: 0.008
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G?ren A, Top?u G, Bilsel G, Bilsel M, Aydogmus Z, Pezzuto JM. The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas. Z Naturforsch C J Biosci. 2002 Sep-Oct; 57(9-10):797-800.
Score: 0.008
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Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-S?nchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. J Nat Prod. 2002 Jun; 65(6):842-50.
Score: 0.007
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Bhat KP, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Ann N Y Acad Sci. 2002 May; 957:210-29.
Score: 0.007
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Mi Q, Cui B, Ch?vez D, Chai H, Zhu H, Cordell GA, Hedayat S, Kinghorn AD, Pezzuto JM. Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype. Anticancer Res. 2002 May-Jun; 22(3):1385-97.
Score: 0.007
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Lee SK, Heo YH, Steele VE, Pezzuto JM. Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells. Anticancer Res. 2002 Jan-Feb; 22(1A):97-102.
Score: 0.007
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Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev. 2002; 21(3-4):231-55.
Score: 0.007
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Ahmad B, Khan MR, Shah NA, Kondratyuk TP, Ahmed N, Pezzuto JM, Gul A, Khattak A. Investigation of Chemopreventive and Antiproliferative Potential of Dicliptera roxburghiana. Integr Cancer Ther. 2022 Jan-Dec; 21:15347354211069934.
Score: 0.007
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Zaman KAU, Hu Z, Wu X, Hou S, Saito J, Kondratyuk TP, Pezzuto JM, Cao S. NF-?B Inhibitory and Antibacterial Helvolic and Fumagillin Derivatives from Aspergillus terreus. J Nat Prod. 2020 03 27; 83(3):730-737.
Score: 0.006
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Heinrich M, Appendino G, Efferth T, F?rst R, Izzo AA, Kayser O, Pezzuto JM, Viljoen A. Best practice in research - Overcoming common challenges in phytopharmacological research. J Ethnopharmacol. 2020 Jan 10; 246:112230.
Score: 0.006
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Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1. Bioorg Med Chem Lett. 2017 12 15; 27(24):5393-5399.
Score: 0.005
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Cai YS, Sarotti AM, G?ndisch D, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities. Bioorg Med Chem Lett. 2017 10 15; 27(20):4630-4634.
Score: 0.005
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Li CS, Sarotti AM, Huang P, Dang UT, Hurdle JG, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. NF-?B inhibitors, unique ?-pyranol-?-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462. Sci Rep. 2017 09 05; 7(1):10424.
Score: 0.005
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Chang LC, Sang-Ngern M, Pezzuto JM, Ma C. The Daniel K. Inouye College of Pharmacy Scripts: Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention Activities. Hawaii J Med Public Health. 2016 11; 75(11):353-359.
Score: 0.005
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Youn UJ, Park EJ, Kondratyuk TP, Sripisut T, Laphookhieo S, Pezzuto JM, Chang LC. Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis. Fitoterapia. 2016 Oct; 114:92-97.
Score: 0.005
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Issa ME, Berndt S, Carpentier G, Pezzuto JM, Cuendet M. Bruceantin inhibits multiple myeloma cancer stem cell proliferation. Cancer Biol Ther. 2016 09; 17(9):966-75.
Score: 0.005
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Sang-Ngern M, Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Wall MM, Ruf M, Lorch SE, Leong E, Pezzuto JM, Chang LC. Withanolides derived from Physalis peruviana (Poha) with potential anti-inflammatory activity. Bioorg Med Chem Lett. 2016 Jun 15; 26(12):2755-2759.
Score: 0.005
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Guan Y, Wang D, Tan GT, Van Hung N, Cuong NM, Pezzuto JM, Fong HH, Soejarto DD, Zhang H. Litsea Species as Potential Antiviral Plant Sources. Am J Chin Med. 2016; 44(2):275-90.
Score: 0.005
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Jafri L, Saleem S, Kondrytuk TP, Haq IU, Ullah N, Pezzuto JM, Mirza B. Hedera nepalensis K. Koch: A Novel Source of Natural Cancer Chemopreventive and Anticancerous Compounds. Phytother Res. 2016 Mar; 30(3):447-53.
Score: 0.005
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Chelsky ZL, Yue P, Kondratyuk TP, Paladino D, Pezzuto JM, Cushman M, Turkson J. A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. Mol Pharmacol. 2015 Sep; 88(3):524-33.
Score: 0.005
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Jabeen F, Panda SS, Kondratyuk TP, Park EJ, Pezzuto JM, Hall CD, Katritzky AR. Synthesis, molecular docking and anticancer studies of peptides and iso-peptides. Bioorg Med Chem Lett. 2015 Aug 01; 25(15):2980-4.
Score: 0.005
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Hussain RA, Badshah A, Pezzuto JM, Ahmed N, Kondratyuk TP, Park EJ. Ferrocene incorporated selenoureas as anticancer agents. J Photochem Photobiol B. 2015 Jul; 148:197-208.
Score: 0.005
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Garc?a ME, Nicotra VE, Oberti JC, R?os-Luci C, Le?n LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padr?n JM, Hueso-Falc?n I, Est?vez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. Eur J Med Chem. 2014 Jul 23; 82:68-81.
Score: 0.004
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Chai X, Youn UJ, Sun D, Dai J, Williams P, Kondratyuk TP, Borris RP, Davies J, Villanueva IG, Pezzuto JM, Chang LC. Herbicidin congeners, undecose nucleosides from an organic extract of Streptomyces sp. L-9-10. J Nat Prod. 2014 Feb 28; 77(2):227-33.
Score: 0.004
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Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M. Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. J Med Chem. 2013 Mar 28; 56(6):2581-605.
Score: 0.004
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Yu X, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NF?B inhibitors. Org Biomol Chem. 2012 Nov 28; 10(44):8835-47.
Score: 0.004
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Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1). Bioorg Med Chem. 2012 Dec 15; 20(24):7030-9.
Score: 0.004
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Archer CR, Groll M, Stein ML, Schellenberg B, Clerc J, Kaiser M, Kondratyuk TP, Pezzuto JM, Dudler R, Bachmann AS. Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells. Biochemistry. 2012 Aug 28; 51(34):6880-8.
Score: 0.004
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Luqman S, Meena A, Singh P, Kondratyuk TP, Marler LE, Pezzuto JM, Negi AS. Neoflavonoids and tetrahydroquinolones as possible cancer chemopreventive agents. Chem Biol Drug Des. 2012 Oct; 80(4):616-24.
Score: 0.004
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Youn UJ, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Tanamatayarat P, Wongwiwatthananukit S, Toyama O, Songsak T, Pezzuto JM, Chang LC. Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorg Med Chem Lett. 2012 Sep 01; 22(17):5559-62.
Score: 0.004
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Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. J Med Chem. 2012 Jun 28; 55(12):5965-81.
Score: 0.004
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Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. Bioorg Med Chem. 2012 Apr 01; 20(7):2427-34.
Score: 0.004
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Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. Bioorg Med Chem. 2012 Jan 01; 20(1):510-20.
Score: 0.004
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Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorg Med Chem. 2011 Nov 01; 19(21):6182-95.
Score: 0.004
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Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, Shukla Y, Surh YJ, Szekeres T, Szkudelski T, Walle T, Wu JM. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One. 2011; 6(6):e19881.
Score: 0.003
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Zou J, Pan L, Li Q, Zhao J, Pu J, Yao P, Gong N, Lu Y, Kondratyuk TP, Pezzuto JM, Fong HH, Zhang H, Sun H. Rubesanolides A and B: diterpenoids from Isodon rubescens. Org Lett. 2011 Mar 18; 13(6):1406-9.
Score: 0.003
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Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Bioactive compounds from the fern Lepisorus contortus. J Nat Prod. 2011 Feb 25; 74(2):129-36.
Score: 0.003
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Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB, van Breemen RR. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 01; 83(3):1048-52.
Score: 0.003
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Conda-Sheridan M, Marler L, Park EJ, Kondratyuk TP, Jermihov K, Mesecar AD, Pezzuto JM, Asolkar RN, Fenical W, Cushman M. Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284. J Med Chem. 2010 Dec 23; 53(24):8688-99.
Score: 0.003
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Calamini B, Ratia K, Malkowski MG, Cuendet M, Pezzuto JM, Santarsiero BD, Mesecar AD. Pleiotropic mechanisms facilitated by resveratrol and its metabolites. Biochem J. 2010 Jul 15; 429(2):273-82.
Score: 0.003
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Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J Med Chem. 2010 Jul 08; 53(13):5033-43.
Score: 0.003
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Nam SJ, Gaud?ncio SP, Kauffman CA, Jensen PR, Kondratyuk TP, Marler LE, Pezzuto JM, Fenical W. Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis. J Nat Prod. 2010 Jun 25; 73(6):1080-6.
Score: 0.003
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Endringer DC, Valadares YM, Campana PR, Campos JJ, Guimar?es KG, Pezzuto JM, Braga FC. Evaluation of Brazilian plants on cancer chemoprevention targets in vitro. Phytother Res. 2010 Jun; 24(6):928-33.
Score: 0.003
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Gullett NP, Ruhul Amin AR, Bayraktar S, Pezzuto JM, Shin DM, Khuri FR, Aggarwal BB, Surh YJ, Kucuk O. Cancer prevention with natural compounds. Semin Oncol. 2010 Jun; 37(3):258-81.
Score: 0.003
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Sun B, Hoshino J, Jermihov K, Marler L, Pezzuto JM, Mesecar AD, Cushman M. Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorg Med Chem. 2010 Jul 15; 18(14):5352-66.
Score: 0.003
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Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 2010 Apr; 71(5-6):641-7.
Score: 0.003
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Deng Y, Balunas MJ, Kim JA, Lantvit DD, Chin YW, Chai H, Sugiarso S, Kardono LB, Fong HH, Pezzuto JM, Swanson SM, de Blanco EJ, Kinghorn AD. Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes. J Nat Prod. 2009 Jun; 72(6):1165-9.
Score: 0.003
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Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities. J Med Chem. 2009 Apr 09; 52(7):1873-84.
Score: 0.003
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Yao G, Kondratyuk TP, Tan GT, Pezzuto JM, Chang LC. Bioactive sulfated sesterterpene alkaloids and sesterterpene sulfates from the marine sponge Fasciospongia sp. J Nat Prod. 2009 Feb 27; 72(2):319-23.
Score: 0.003
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Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metab Dispos. 2008 Oct; 36(10):2104-12.
Score: 0.003
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Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorg Med Chem. 2009 Feb 01; 17(3):1044-54.
Score: 0.003
-
Endringer DC, Guimar?es KG, Kondratyuk TP, Pezzuto JM, Braga FC. Selective inhibition of aromatase by a dihydroisocoumarin from Xyris pterygoblephara. J Nat Prod. 2008 Jun; 71(6):1082-4.
Score: 0.003
-
Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metab Dispos. 2008 Feb; 36(2):461-8.
Score: 0.003
-
Liu D, Guo J, Luo Y, Broderick DJ, Schimerlik MI, Pezzuto JM, van Breemen RB. Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry. Anal Chem. 2007 Dec 15; 79(24):9398-402.
Score: 0.003
-
Maiti A, Cuendet M, Croy VL, Endringer DC, Pezzuto JM, Cushman M. Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer. J Med Chem. 2007 Jun 14; 50(12):2799-806.
Score: 0.003
-
Maiti A, Cuendet M, Kondratyuk T, Croy VL, Pezzuto JM, Cushman M. Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. J Med Chem. 2007 Jan 25; 50(2):350-5.
Score: 0.003
-
Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutr Cancer. 2007; 57(1):28-37.
Score: 0.003
-
Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. FEBS J. 2006 Dec; 273(24):5714-23.
Score: 0.003
-
Balunas MJ, Jones WP, Chin YW, Mi Q, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Chai HB, Kinghorn AD. Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project. Chem Biodivers. 2006 Aug; 3(8):897-915.
Score: 0.002
-
He ZD, Ma CY, Tan GT, Sydara K, Tamez P, Southavong B, Bouamanivong S, Soejarto DD, Pezzuto JM, Fong HH, Zhang HJ. Rourinoside and rouremin, antimalarial constituents from Rourea minor. Phytochemistry. 2006 Jul; 67(13):1378-84.
Score: 0.002
-
Fang L, Ito A, Chai HB, Mi Q, Jones WP, Madulid DR, Oliveros MB, Gao Q, Orjala J, Farnsworth NR, Soejarto DD, Cordell GA, Swanson SM, Pezzuto JM, Kinghorn AD. Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines. J Nat Prod. 2006 Mar; 69(3):332-7.
Score: 0.002
-
Homhual S, Zhang HJ, Bunyapraphatsara N, Kondratyuk TP, Santarsiero BD, Mesecar AD, Herunsalee A, Chaukul W, Pezzuto JM, Fong HH. Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza. Planta Med. 2006 Feb; 72(3):255-60.
Score: 0.002
-
Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. J Med Chem. 2006 Jan 26; 49(2):693-708.
Score: 0.002
-
Jones WP, Lobo-Echeverri T, Mi Q, Chai H, Lee D, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. J Pharm Pharmacol. 2005 Sep; 57(9):1101-8.
Score: 0.002
-
Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10070-5.
Score: 0.002
-
Zhang HJ, Nguyen VH, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata. Planta Med. 2005 May; 71(5):452-7.
Score: 0.002
-
Lobo-Echeverri T, Rivero-Cruz JF, Su BN, Chai HB, Cordell GA, Pezzuto JM, Swanson SM, Soejarto DD, Kinghorn AD. Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida. J Nat Prod. 2005 Apr; 68(4):577-80.
Score: 0.002
-
Rivero-Cruz JF, Lezutekong R, Lobo-Echeverri T, Ito A, Mi Q, Chai HB, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Morelli I, Kinghorn AD. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida. Phytother Res. 2005 Feb; 19(2):136-40.
Score: 0.002
-
Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2. Planta Med. 2004 Oct; 70(10):893-6.
Score: 0.002
-
Gu JQ, Graf TN, Lee D, Chai HB, Mi Q, Kardono LB, Setyowati FM, Ismail R, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kroll DJ, Falkinham JO, Wall ME, Wani MC, Kinghorn AD, Oberlies NH. Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. J Nat Prod. 2004 Jul; 67(7):1156-61.
Score: 0.002
-
Nguyen QC, Nguyen VH, Santarsiero BD, Mesecar AD, Nguyen MC, Soejarto DD, Pezzuto JM, Fong HH, Tan GT. New 3-O-acyl betulinic acids from Strychnos vanprukii Craib. J Nat Prod. 2004 Jun; 67(6):994-8.
Score: 0.002
-
Hwang BY, Su BN, Chai H, Mi Q, Kardono LB, Afriastini JJ, Riswan S, Santarsiero BD, Mesecar AD, Wild R, Fairchild CR, Vite GD, Rose WC, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris. J Org Chem. 2004 May 14; 69(10):3350-8.
Score: 0.002
-
Rivero-Cruz JF, Chai HB, Kardono LB, Setyowati FM, Afriatini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa. J Nat Prod. 2004 Mar; 67(3):343-7.
Score: 0.002
-
Diaz F, Chai HB, Mi Q, Su BN, Vigo JS, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru. J Nat Prod. 2004 Mar; 67(3):352-6.
Score: 0.002
-
Lee HY, Suh YA, Kosmeder JW, Pezzuto JM, Hong WK, Kurie JM. Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clin Cancer Res. 2004 Feb 01; 10(3):1074-9.
Score: 0.002
-
Zhang HJ, Sydara K, Tan GT, Ma C, Southavong B, Soejarto DD, Pezzuto JM, Fong HH. Bioactive constituents from Asparagus cochinchinensis. J Nat Prod. 2004 Feb; 67(2):194-200.
Score: 0.002
-
Ito A, Chai HB, Kardono LB, Setowati FM, Afriastini JJ, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Saponins from the bark of Nephelium maingayi. J Nat Prod. 2004 Feb; 67(2):201-5.
Score: 0.002
-
Li Y, Shin YG, Yu C, Kosmeder JW, Hirschelman WH, Pezzuto JM, van Breemen RB. Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism. Comb Chem High Throughput Screen. 2003 Dec; 6(8):757-67.
Score: 0.002
-
Burdette JE, Liu J, Chen SN, Fabricant DS, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, Van Breemen RB, Farnsworth NR, Bolton JL. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J Agric Food Chem. 2003 Sep 10; 51(19):5661-70.
Score: 0.002
-
Lee KH, Chai HB, Tamez PA, Pezzuto JM, Cordell GA, Win KK, Tin-Wa M. Biologically active alkylated coumarins from Kayea assamica. Phytochemistry. 2003 Sep; 64(2):535-41.
Score: 0.002
-
Mi Q, Cui B, Lantvit D, Reyes-Lim E, Chai H, Pezzuto JM, Kinghorn AD, Swanson SM. Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance. Anticancer Res. 2003 Sep-Oct; 23(5A):3607-15.
Score: 0.002
-
D?az F, Ch?vez D, Lee D, Mi Q, Chai HB, Tan GT, Kardono LB, Riswan S, Fairchild CR, Wild R, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J Nat Prod. 2003 Jun; 66(6):865-7.
Score: 0.002
-
Fang L, Chai HB, Castillo JJ, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic constituents of Brachistus stramoniifolius. Phytother Res. 2003 May; 17(5):520-3.
Score: 0.002
-
Gafner S, Bergeron C, Batcha LL, Reich J, Arnason JT, Burdette JE, Pezzuto JM, Angerhofer CK. Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. J Nat Prod. 2003 Apr; 66(4):535-7.
Score: 0.002
-
Chun KH, Kosmeder JW, Sun S, Pezzuto JM, Lotan R, Hong WK, Lee HY. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J Natl Cancer Inst. 2003 Feb 19; 95(4):291-302.
Score: 0.002
-
Zhang HJ, Tan GT, Hoang VD, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH. Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea. J Nat Prod. 2003 Feb; 66(2):263-8.
Score: 0.002
-
Seo EK, Lee D, Shin YG, Chai HB, Navarro HA, Kardono LB, Rahman I, Cordell GA, Farnsworth NR, Pezzuto JM, Kinghorn AD, Wani MC, Wall ME. Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando. Arch Pharm Res. 2003 Feb; 26(2):124-7.
Score: 0.002
-
Hwang BY, Chai HB, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic triterpenes from the twigs of Celtis philippinensis. Phytochemistry. 2003 Jan; 62(2):197-201.
Score: 0.002
-
Yu C, Shin YG, Kosmeder JW, Pezzuto JM, van Breemen RB. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun Mass Spectrom. 2003; 17(4):307-13.
Score: 0.002
-
Calder?n AI, Terreaux C, Schenk K, Pattison P, Burdette JE, Pezzuto JM, Gupta MP, Hostettmann K. Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis. J Nat Prod. 2002 Dec; 65(12):1749-53.
Score: 0.002
-
Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, Lee YS, Hirschelman WH, Pezzuto JM, Mehta RG, van Breemen RB. Human, rat, and mouse metabolism of resveratrol. Pharm Res. 2002 Dec; 19(12):1907-14.
Score: 0.002
-
Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. J Agric Food Chem. 2002 Nov 20; 50(24):7022-8.
Score: 0.002
-
Ito A, Chai HB, Lee D, Kardono LB, Riswan S, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. Phytochemistry. 2002 Sep; 61(2):171-4.
Score: 0.002
-
Su BN, Chang LC, Park EJ, Cuendet M, Santarsiero BD, Mesecar AD, Mehta RG, Fong HH, Pezzuto JM, Kinghorn AD. Bioactive constituents of the seeds of Brucea javanica. Planta Med. 2002 Aug; 68(8):730-3.
Score: 0.002
-
Blatt CT, Ch?vez D, Chai H, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. Phytother Res. 2002 Jun; 16(4):320-5.
Score: 0.002
-
Gu JQ, Gills JJ, Park EJ, Mata-Greenwood E, Hawthorne ME, Axelrod F, Chavez PI, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity. J Nat Prod. 2002 Apr; 65(4):532-6.
Score: 0.002
-
Ch?vez D, Cui B, Chai HB, Garc?a R, Mej?a M, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium. J Nat Prod. 2002 Apr; 65(4):606-10.
Score: 0.002
-
Minguzzi S, Barata LE, Shin YG, Jonas PF, Chai HB, Park EJ, Pezzuto JM, Cordell GA. Cytotoxic withanolides from Acnistus arborescens. Phytochemistry. 2002 Mar; 59(6):635-41.
Score: 0.002
-
Zhang H, Fan Z, Tan GT, Chai HB, Pezzuto JM, Sun H, Fong HH. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata. J Nat Prod. 2002 Feb; 65(2):215-7.
Score: 0.002
-
Peraza-S?nchez SR, Chai HB, Shin YG, Santisuk T, Reutrakul V, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Constituents of the leaves and twigs of Ficus hispida. Planta Med. 2002 Feb; 68(2):186-8.
Score: 0.002