John Pezzuto to Antineoplastic Agents
This is a "connection" page, showing publications John Pezzuto has written about Antineoplastic Agents.
Connection Strength
2.550
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Cragg GM, Pezzuto JM. Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents. Med Princ Pract. 2016; 25 Suppl 2:41-59.
Score: 0.340
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Ogas T, Kondratyuk TP, Pezzuto JM. Resveratrol analogs: promising chemopreventive agents. Ann N Y Acad Sci. 2013 Jul; 1290:21-9.
Score: 0.286
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Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prev Res (Phila). 2011 Apr; 4(4):592-607.
Score: 0.245
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Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prev Res (Phila). 2010 Feb; 3(2):221-32.
Score: 0.225
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Lee SK, Heo YH, Steele VE, Pezzuto JM. Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells. Anticancer Res. 2002 Jan-Feb; 22(1A):97-102.
Score: 0.129
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Zhang M, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis and Structure-Activity Relationships of Tetrahydro-?-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents. Anticancer Res. 2018 Aug; 38(8):4425-4433.
Score: 0.102
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Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1. Bioorg Med Chem Lett. 2017 12 15; 27(24):5393-5399.
Score: 0.097
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Chelsky ZL, Yue P, Kondratyuk TP, Paladino D, Pezzuto JM, Cushman M, Turkson J. A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells. Mol Pharmacol. 2015 Sep; 88(3):524-33.
Score: 0.082
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Jabeen F, Panda SS, Kondratyuk TP, Park EJ, Pezzuto JM, Hall CD, Katritzky AR. Synthesis, molecular docking and anticancer studies of peptides and iso-peptides. Bioorg Med Chem Lett. 2015 Aug 01; 25(15):2980-4.
Score: 0.081
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Hussain RA, Badshah A, Pezzuto JM, Ahmed N, Kondratyuk TP, Park EJ. Ferrocene incorporated selenoureas as anticancer agents. J Photochem Photobiol B. 2015 Jul; 148:197-208.
Score: 0.081
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Garc?a ME, Nicotra VE, Oberti JC, R?os-Luci C, Le?n LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padr?n JM, Hueso-Falc?n I, Est?vez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. Eur J Med Chem. 2014 Jul 23; 82:68-81.
Score: 0.076
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Mayhoub AS, Marler L, Kondratyuk TP, Park EJ, Pezzuto JM, Cushman M. Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. Bioorg Med Chem. 2012 Jan 01; 20(1):510-20.
Score: 0.063
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Shen L, Park EJ, Kondratyuk TP, Guendisch D, Marler L, Pezzuto JM, Wright AD, Sun D. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorg Med Chem. 2011 Nov 01; 19(21):6182-95.
Score: 0.063
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Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, Fong HH, Chen YG, Zhang HJ. Bioactive compounds from the fern Lepisorus contortus. J Nat Prod. 2011 Feb 25; 74(2):129-36.
Score: 0.060
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Schupp PJ, Kohlert-Schupp C, Whitefield S, Engemann A, Rohde S, Hemscheidt T, Pezzuto JM, Kondratyuk TP, Park EJ, Marler L, Rostama B, Wright AD. Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam. Nat Prod Commun. 2009 Dec; 4(12):1717-28.
Score: 0.056
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Mi Q, Pezzuto JM, Farnsworth NR, Wani MC, Kinghorn AD, Swanson SM. Use of the in vivo hollow fiber assay in natural products anticancer drug discovery. J Nat Prod. 2009 Mar 27; 72(3):573-80.
Score: 0.053
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Yao G, Kondratyuk TP, Tan GT, Pezzuto JM, Chang LC. Bioactive sulfated sesterterpene alkaloids and sesterterpene sulfates from the marine sponge Fasciospongia sp. J Nat Prod. 2009 Feb 27; 72(2):319-23.
Score: 0.053
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Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metab Dispos. 2008 Feb; 36(2):461-8.
Score: 0.048
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Choi JK, Murillo G, Su BN, Pezzuto JM, Kinghorn AD, Mehta RG. Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells. FEBS J. 2006 Dec; 273(24):5714-23.
Score: 0.045
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Wright AD, de Nys R, Angerhofer CK, Pezzuto JM, Gurrath M. Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products. J Nat Prod. 2006 Aug; 69(8):1180-7.
Score: 0.044
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Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. J Med Chem. 2006 Jan 26; 49(2):693-708.
Score: 0.043
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Lee HY, Oh SH, Woo JK, Kim WY, Van Pelt CS, Price RE, Cody D, Tran H, Pezzuto JM, Moriarty RM, Hong WK. Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J Natl Cancer Inst. 2005 Nov 16; 97(22):1695-9.
Score: 0.042
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Jones WP, Lobo-Echeverri T, Mi Q, Chai H, Lee D, Soejarto DD, Cordell GA, Pezzuto JM, Swanson SM, Kinghorn AD. Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida. J Pharm Pharmacol. 2005 Sep; 57(9):1101-8.
Score: 0.042
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Mi Q, Cui B, Lantvit D, Reyes-Lim E, Chai H, Pezzuto JM, Kinghorn AD, Swanson SM. Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance. Anticancer Res. 2003 Sep-Oct; 23(5A):3607-15.
Score: 0.036
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Chun KH, Kosmeder JW, Sun S, Pezzuto JM, Lotan R, Hong WK, Lee HY. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J Natl Cancer Inst. 2003 Feb 19; 95(4):291-302.
Score: 0.035
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Mehta RG, Pezzuto JM. Discovery of cancer preventive agents from natural products: from plants to prevention. Curr Oncol Rep. 2002 Nov; 4(6):478-86.
Score: 0.034
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Minguzzi S, Barata LE, Shin YG, Jonas PF, Chai HB, Park EJ, Pezzuto JM, Cordell GA. Cytotoxic withanolides from Acnistus arborescens. Phytochemistry. 2002 Mar; 59(6):635-41.
Score: 0.033
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Archer CR, Groll M, Stein ML, Schellenberg B, Clerc J, Kaiser M, Kondratyuk TP, Pezzuto JM, Dudler R, Bachmann AS. Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells. Biochemistry. 2012 Aug 28; 51(34):6880-8.
Score: 0.017
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Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. J Med Chem. 2010 Jul 08; 53(13):5033-43.
Score: 0.015
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Maiti A, Reddy PV, Sturdy M, Marler L, Pegan SD, Mesecar AD, Pezzuto JM, Cushman M. Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities. J Med Chem. 2009 Apr 09; 52(7):1873-84.
Score: 0.013
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Jang DS, Cuendet M, Hawthorne ME, Kardono LB, Kawanishi K, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2. Phytochemistry. 2002 Dec; 61(7):867-72.
Score: 0.009