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Vaikom S Mahadevan MD, FRCP, FACC, FSCAI

TitleProfessor
Endowed TitleEdward Budnitz, MD, Professor in Cardiovascular Medicine
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
Phone508-856-8989
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine
    DivisionCardiovascular Medicine


    Collapse Biography 
    Collapse education and training
    Stanley Medical College, Chennai, TN, IndiaBS
    Stanley Medical College, Chennai, TN, IndiaMD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Moons P, Kovacs AH, Goossens E, Luyckx K, Ladak L, Leye M, Van De Bruaene A, Leong MC, Kaneva A, Manso PH, Araujo JJ, Sasikumar N, Gabriel H, Yadeta D, Wang JK, Enomoto J, Areias ME, Kosmidis D, Coats L, Valente AM, Moon JR, Ladouceur M, Thomet C, Jackson JL, Sandberg C, Callus E, Kim YY, Lykkeberg B, Alday L, Bredy C, Saidi A, Baraona Reyes F, Menahem S, de Hosson M, Hlebowicz J, Christersson C, Zaidi AN, Johansson B, Andresen B, Ambassa JC, Mattsson E, Constantine A, Amedro P, van Melle JP, Kutty S, Ortiz L, Demir F, Khairy P, Windram J, Bouchardy J, Caruana M, Jameson SM, Mahadevan VS, McGrath LB, Mwita JC, Van Bulck L. Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries. Heart. 2025 Aug 12; 111(17):818-827. PMID: 40579213.
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    2. Lawlor M, Katukuri N, Balsam L, Walker J, Gentile B, Mahadevan V, Kakouros N. Transcatheter Mitral Valve-in-Valve Replacement With Balloon-Assisted Translocation in Calcified Mitral Anterior Leaflet. JACC Case Rep. 2025 Jul 16; 30(19):104045. PMID: 40681277.
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    3. Judson GL, Luck J, Lawrence S, Khaki R, Agrawal H, Soni K, Tolstrup K, Jaganathan V, Mahadevan VS. Predictors of Length-of-Stay Among Transcatheter Aortic Valve Replacement Patients Using a Supervised Machine Learning Algorithm. JACC Adv. 2025 Aug; 4(8):101902. PMID: 40561612.
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    4. Krishna MM, Joseph M, Ezenna C, Pereira V, Rossi R, Akman Z, Rubens M, Mahadevan VS, Nanna MG, Goldsweig AM. TAVR vs. SAVR for severe aortic stenosis in the low and intermediate surgical risk population: An updated meta-analysis, meta-regression, and trial sequential analysis. Cardiovasc Revasc Med. 2025 Oct; 79:78-89. PMID: 40425422.
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    5. Dimas VV, Babaliaros V, Kim D, Lim DS, Morgan G, Jones TK, Armstrong AK, Berman D, Aboulhosn J, Mahadevan VS, Gillespie MJ, Balzer D, Zellers T, Yu X, Shirali G, Parthiban A, Leipsic J, Blanke P, Zahn E, Shahanavaz S. Multicenter Pivotal Study of the Alterra Adaptive Prestent for the Treatment of Pulmonary Regurgitation. JACC Cardiovasc Interv. 2024 Oct 14; 17(19):2287-2297. PMID: 39415386.
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    6. Jaganathan V, Rastogi U, Kakouros N, Senser E, Walker J, Mahadevan VS. Thrombus vs Tumor: Use of AngioVac in a RV Mass. JACC Case Rep. 2024 Oct 02; 29(19):102600. PMID: 39484331.
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    7. Tang GHL, Zaid S, Hahn RT, Aggarwal V, Alkhouli M, Aman E, Berti S, Chandrashekhar YS, Chadderdon SM, D'Agostino A, Fam NP, Ho EC, Kliger C, Kodali SK, Krishnamoorthy P, Latib A, Lerakis S, Lim DS, Mahadevan VS, Nair DG, Narula J, O'Gara PT, Packer DL, Praz F, Rogers JH, Ruf TF, Sanchez CE, Sharma A, Singh GD, van Mieghem NM, Vannan MA, Yadav PK, Ya'Qoub L, Zahr FE, von Bardeleben RS. Structural Heart Imaging Using 3-Dimensional Intracardiac Echocardiography: JACC: Cardiovascular Imaging Position Statement. JACC Cardiovasc Imaging. 2025 Jan; 18(1):93-115. PMID: 38970594.
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    8. Ya'Qoub L, Caughron H, Qasim A, Tolstrop K, Delling FN, Watt C, Nguyen T, Deuse T, Beygui RE, Mahadevan VS. Clinical Improvement With Transcatheter Edge-to-Edge Tricuspid Repair Irrespective of Right Atrial Pressure. JACC Adv. 2024 Apr; 3(4):100862. PMID: 38939678.
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    9. Goli R, Ya'Qoub L, Blusztein D, Mahadevan VS. Treatment of left main coronary artery compression in the setting of unpalliated congenital heart disease: a case series. Eur Heart J Case Rep. 2023 Aug; 7(8):ytad262. PMID: 37601230.
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    10. Tagliari AP, Taramasso M, Mahadevan VS. Approaching the Gap: Optimizing Tricuspid Valve Coaptation During Transcatheter Tricuspid Repair. JACC Case Rep. 2023 Jun 07; 15:101854. PMID: 37283830.
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    11. Wong P, Wisneski AD, Sandhu A, Wang Z, Mahadevan VS, Nguyen TC, Guccione JM. Looking towards the future: patient-specific computational modeling to optimize outcomes for transcatheter mitral valve repair. Front Cardiovasc Med. 2023; 10:1140379. PMID: 37168656.
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    12. Fischman DL, Mahadevan VS, Bates ER. The "Evolving" Role of Intravascular Imaging in Myocardial Infarction With Nonobstructive Coronary Arteries. JACC Case Rep. 2023 Jan 18; 6:101701. PMID: 36704053.
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    13. Mital R, Ramakrishna S, Judson GL, Watt C, Tolstrup K, Mahadevan VS. Transcatheter Edge-to-Edge Repair for Left Atrioventricular Valve Cleft After Previously Repaired Complete Atrioventricular Canal Defect in Down Syndrome. CASE (Phila). 2023 Jan; 7(1):35-38. PMID: 36704485.
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    14. Tuwairqi K, Salahuddin A, Judson G, Blusztein D, Moore P, Anwar S, Mahadevan VS. First in Human: Transcatheter Repair of Isolated Partial Anomalous Pulmonary Venous Return. Circ Cardiovasc Interv. 2022 09; 15(9):e012132. PMID: 35993235.
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    15. Judson GL, Mahadevan VS. Valves, Vegetations, and Valves. J Invasive Cardiol. 2022 07; 34(7):E580. PMID: 35772932.
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    16. Van Bulck L, Kovacs AH, Goossens E, Luyckx K, Zaidi A, Wang JK, Yadeta D, Windram J, Van De Bruaene A, Thomet C, Thambo JB, Taunton M, Sasikumar N, Sandberg C, Saidi A, Rutz T, Ortiz L, Mwita JC, Moon JR, Menahem S, Mattsson E, Mandalenakis Z, Mahadevan VS, Lykkeberg B, Leye M, Leong MC, Ladouceur M, Ladak LA, Kim Y, Khairy P, Kaneva A, Johansson B, Jackson JL, Giannakoulas G, Gabriel H, Fernandes SM, Enomoto J, Demir F, de Hosson M, Constantine A, Coats L, Christersson C, Cedars A, Caruana M, Callus E, Brainard S, Bouchardy J, Boer A, Baraona Reyes F, Areias ME, Araujo JJ, Andresen B, Amedro P, Ambassa JC, Amaral F, Alday L, Moons P. Rationale, design and methodology of APPROACH-IS II: International study of patient-reported outcomes and frailty phenotyping in adults with congenital heart disease. Int J Cardiol. 2022 09 15; 363:30-39. PMID: 35780933.
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    17. Ya'Qoub L, Alqarqaz M, Mahadevan VS, Saad M, Elgendy IY. Impact of COVID-19 on Management Strategies for Coronary and Structural Heart Disease Interventions. Curr Cardiol Rep. 2022 06; 24(6):679-687. PMID: 35347567.
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    18. Melo D, Agrawal H, Parikh DS, Sarwary S, Lin S, Choy HH, Mallawaarachchi I, Kallianos K, Hope M, Mahadevan VS. Accuracy of Ferumoxytol-Enhanced MRA-Guided TAVR in Patients With Chronic Kidney Disease. JACC Cardiovasc Interv. 2022 03 28; 15(6):677-679. PMID: 35331463.
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    19. Dabiri Y, Mahadevan VS, Guccione JM, Kassab GS. A Simulation Study of the Effects of Number and Location of MitraClips on Mitral Regurgitation. JACC Adv. 2022 Mar; 1(1):100015. PMID: 38939090.
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    20. Blusztein D, Moore P, Qasim A, Mantri N, Mahadevan VS. Transcatheter Edge-to-Edge Repair of?Systemic Tricuspid Valve in Extracardiac Fontan Circulation: First in Human. JACC Case Rep. 2022 Feb 16; 4(4):221-225. PMID: 35199020.
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    21. Dabiri Y, Yao J, Mahadevan VS, Gruber D, Arnaout R, Gentzsch W, Guccione JM, Kassab GS. Mitral Valve Atlas for Artificial Intelligence Predictions of MitraClip Intervention Outcomes. Front Cardiovasc Med. 2021; 8:759675. PMID: 34957251.
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    22. Rosenthal DG, Blusztein D, Mahadevan VS, Gerstenfeld EP. Misleading Placement of a Dual-Chamber Pacemaker. JACC Clin Electrophysiol. 2022 01; 8(1):136-137. PMID: 34454877.
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    23. Chorba JS, Shapiro AM, Le L, Maidens J, Prince J, Pham S, Kanzawa MM, Barbosa DN, Currie C, Brooks C, White BE, Huskin A, Paek J, Geocaris J, Elnathan D, Ronquillo R, Kim R, Alam ZH, Mahadevan VS, Fuller SG, Stalker GW, Bravo SA, Jean D, Lee JJ, Gjergjindreaj M, Mihos CG, Forman ST, Venkatraman S, McCarthy PM, Thomas JD. Deep Learning Algorithm for Automated Cardiac Murmur Detection via a Digital Stethoscope Platform. J Am Heart Assoc. 2021 05 04; 10(9):e019905. PMID: 33899504.
      Citations:    
    24. Caughron H, Parikh D, Allison Z, Deuse T, Mahadevan VS. Outcomes of transcatheter aortic valve replacement in end stage liver and renal disease. Catheter Cardiovasc Interv. 2021 07 01; 98(1):159-167. PMID: 33594809.
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    25. Parikh DS, Blissett S, Tolstrup K, Mahadevan VS. A Complex Tricuspid Clip: Bridging the Decision. JACC Case Rep. 2020 Jul; 2(8):1089-1092. PMID: 34317421.
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    26. Judson GL, Kelemen BW, Njoroge JN, Mahadevan VS. Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection. Cardiol Ther. 2020 Dec; 9(2):293-305. PMID: 32535752.
      Citations:    
    27. Curran L, Agrawal H, Kallianos K, Kheiwa A, Lin S, Ordovas K, Mahadevan VS. Computed tomography guided sizing for transcatheter pulmonary valve replacement. Int J Cardiol Heart Vasc. 2020 Aug; 29:100523. PMID: 32885027.
      Citations:    
    28. Agarwal A, Thombley R, Broberg CS, Harris IS, Foster E, Mahadevan VS, John A, Vittinghoff E, Marcus GM, Dudley RA. Age- and Lesion-Related Comorbidity Burden Among US Adults With Congenital Heart Disease: A Population-Based Study. J Am Heart Assoc. 2019 10 15; 8(20):e013450. PMID: 31575318.
      Citations:    
    29. Judson GL, Agrawal H, Mahadevan VS. Conduction System Abnormalities After Transcatheter Aortic Valve Replacement: Mechanism, Prediction, and Management. Interv Cardiol Clin. 2019 10; 8(4):403-409. PMID: 31445724.
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    30. Agrawal H, Agarwal A, Eichler CM, Mahadevan VS. Percutaneous exclusion of a giant ascending aortic pseudoaneurysm. BMJ Case Rep. 2019 Jul 12; 12(7). PMID: 31302626.
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    31. Singh SP, Agrawal H, Eichler CM, Mahadevan VS. Percutaneous exclusion of post-transcatheter aortic valve replacement (TAVR) induced aortic pseudoaneurysm using an Amplatzer Vascular Plug 2 (AVP2). BMJ Case Rep. 2019 Jul 02; 12(7). PMID: 31270085.
      Citations:    
    32. Guerrero M, Urena M, Himbert D, Wang DD, Eleid M, Kodali S, George I, Chakravarty T, Mathur M, Holzhey D, Pershad A, Fang HK, O'Hair D, Jones N, Mahadevan VS, Dumonteil N, Rod?s-Cabau J, Piazza N, Ferrari E, Ciaburri D, Nejjari M, DeLago A, Sorajja P, Zahr F, Rajagopal V, Whisenant B, Shah PB, Sinning JM, Witkowski A, Eltchaninoff H, Dvir D, Martin B, Attizzani GF, Gaia D, Nunes NSV, Fassa AA, Kerendi F, Pavlides G, Iyer V, Kaddissi G, Witzke C, Wudel J, Mishkel G, Raybuck B, Wang C, Waksman R, Palacios I, Cribier A, Webb J, Bapat V, Reisman M, Makkar R, Leon M, Rihal C, Vahanian A, O'Neill W, Feldman T. 1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Mitral Annular Calcification. J Am Coll Cardiol. 2018 05 01; 71(17):1841-1853. PMID: 29699609.
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    33. Marcus SG, Mahadevan VS, Deuse T. Hybrid Open Minimally Invasive Transcatheter Mitral Valve Replacement. Ann Thorac Surg. 2018 08; 106(2):e57-e59. PMID: 29605597.
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    34. Agrawal H, Mahadevan VS, Shunk K, Lee MS. Fractional Flow Reserve and Intravascular Ultrasound of Coronary Artery Lesions Beyond the Left Main: A Review of Literature. Rev Cardiovasc Med. 2018 Mar 30; 19(1):1-11. PMID: 31032597.
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    35. Kheiwa A, Divanji P, Mahadevan VS. Transcatheter pulmonary valve implantation: will it replace surgical pulmonary valve replacement? Expert Rev Cardiovasc Ther. 2018 Mar; 16(3):197-207. PMID: 29433351.
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    36. Guerrero M, Dvir D, Himbert D, Urena M, Eleid M, Wang DD, Greenbaum A, Mahadevan VS, Holzhey D, O'Hair D, Dumonteil N, Rod?s-Cabau J, Piazza N, Palma JH, DeLago A, Ferrari E, Witkowski A, Wendler O, Kornowski R, Martinez-Clark P, Ciaburri D, Shemin R, Alnasser S, McAllister D, Bena M, Kerendi F, Pavlides G, Sobrinho JJ, Attizzani GF, George I, Nickenig G, Fassa AA, Cribier A, Bapat V, Feldman T, Rihal C, Vahanian A, Webb J, O'Neill W. Transcatheter Mitral Valve Replacement in?Native?Mitral Valve Disease With Severe?Mitral?Annular Calcification: Results From the First Multicenter Global Registry. JACC Cardiovasc Interv. 2016 07 11; 9(13):1361-71. PMID: 27388824.
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    37. Mahadevan VS, Manoly I, Hasan R. 2-Year Follow-Up of the First in Human Transapical Implantation of Transcatheter Inverted Aortic Valve to Treat Native Mitral Valve Stenosis. JACC Cardiovasc Interv. 2015 Dec 28; 8(15):e247-e249. PMID: 26738679.
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    38. Kesarwani M, Ports TA, Rao RK, Mahadevan VS. First-in-Human Transcatheter Pulmonic Valve Implantation Through a Tricuspid Valve Bioprosthesis to Treat Native Pulmonary Valve Regurgitation Caused by Carcinoid Syndrome. JACC Cardiovasc Interv. 2015 Aug 24; 8(10):e161-e163. PMID: 26315750.
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    39. Soni K, Kesarwani M, Badhwar N, Mahadevan VS. Percutaneous Closure of a Residual Left Atrial Appendage Leak After Lariat Procedure. JACC Cardiovasc Interv. 2015 Jun; 8(7):998-1000. PMID: 26003017.
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