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One or more keywords matched the following items that are connected to Clapham, Paul
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Academic Article Gag regulates association of human immunodeficiency virus type 1 envelope with detergent-resistant membranes.
Academic Article T-cell line adaptation of human immunodeficiency virus type 1 strain SF162: effects on envelope, vpu and macrophage-tropism.
Academic Article Effects of vpu start-codon mutations on human immunodeficiency virus type 1 replication in macrophages.
Academic Article Two closely related Env antigens from the same patient elicited different spectra of neutralizing antibodies against heterologous HIV-1 isolates.
Academic Article Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.
Academic Article Human immunodeficiency viruses: propagation, quantification, and storage.
Academic Article Identification of a subset of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains able to exploit an alternative coreceptor on untransformed human brain and lymphoid cells.
Academic Article CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo.
Academic Article Human immunodeficiency virus type 1 envelope glycoproteins that lack cytoplasmic domain cysteines: impact on association with membrane lipid rafts and incorporation onto budding virus particles.
Academic Article Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages.
Academic Article The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes.
Academic Article Inhibition of CCR5-mediated infection by diverse R5 and R5X4 HIV and SIV isolates using novel small molecule inhibitors of CCR5: effects of viral diversity, target cell and receptor density.
Academic Article Envelope conformational changes induced by human immunodeficiency virus type 1 attachment inhibitors prevent CD4 binding and downstream entry events.
Academic Article Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis.
Academic Article Variation of macrophage tropism among HIV-1 R5 envelopes in brain and other tissues.
Academic Article Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop.
Academic Article Human immunodeficiency viruses: propagation, quantification, and storage.
Academic Article Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes.
Academic Article Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infection.
Academic Article Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia.
Academic Article Modulation of HIV-1 macrophage-tropism among R5 envelopes occurs before detection of neutralizing antibodies.
Academic Article Intercompartmental recombination of HIV-1 contributes to env intrahost diversity and modulates viral tropism and sensitivity to entry inhibitors.
Academic Article Genotypic and functional properties of early infant HIV-1 envelopes.
Concept Human Immunodeficiency Virus Proteins
Concept Acquired Immunodeficiency Syndrome
Concept Simian Acquired Immunodeficiency Syndrome
Concept Simian Immunodeficiency Virus
Concept env Gene Products, Human Immunodeficiency Virus
Academic Article HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.
Academic Article Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.
Academic Article Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications.
Academic Article HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.
Academic Article Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues.
Academic Article No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications.
Academic Article Implications of the 375W mutation for HIV-1 tropism and vaccine development.
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