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One or more keywords matched the following properties of Kornfeld, Hardy
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The Kornfeld Laboratory Link

Education

Medical School: Boston University School of Medicine, Boston, MA, 1978.
Medical Residency: University Hospital, Boston, MA, 1980.
St Luke's Hospital, NY, NY, 1981.
Infectious Disease Fellowship: St Luke's-Roosevelt Hospital Center, NY, NY, 1982.
Pulmonary Fellowship: Boston University School of Medicine, Boston, MA, 1985.
Molecular virology Fellowship: Harvard School of Public Health, Boston, MA, 1987.

Clinical, educational, scientific interests

Tuberculosis
Immunology
Host defense against respiratory pathogens
Impact of metabolic disorders on host defense
Critical care

Research Activities:

1. Role of macrophage apoptosis in TB defense
2. Impact of diabetes and hyperlipidemia on TB defense
3. Role of IL-16 in protective immunity
4. Heterologous immunity between viruses and mycobacteria

One or more keywords matched the following items that are connected to Kornfeld, Hardy
Item TypeName
Academic Article Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis.
Academic Article Induction of gamma interferon production in human alveolar macrophages by Mycobacterium tuberculosis.
Academic Article THP-1 cell apoptosis in response to Mycobacterial infection.
Academic Article Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice.
Academic Article Tuberculosis susceptibility of diabetic mice.
Academic Article Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database.
Academic Article Hypercholesterolemia impairs immunity to tuberculosis.
Academic Article Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence.
Academic Article Macrophage apoptosis in tuberculosis.
Academic Article Initiation of acquired immunity in the lungs of mice lacking lymph nodes after infection with aerosolized Mycobacterium tuberculosis.
Academic Article Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis.
Academic Article Beta-chemokines are induced by Mycobacterium tuberculosis and inhibit its growth.
Academic Article Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages.
Academic Article Interactions between naïve and infected macrophages reduce Mycobacterium tuberculosis viability.
Academic Article Hypercholesterolemic LDL receptor-deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity.
Academic Article Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1?.
Academic Article Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor.
Academic Article Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential.
Academic Article Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway.
Academic Article CD4 T-cell-mediated heterologous immunity between mycobacteria and poxviruses.
Academic Article Intrathymic programming of effector fates in three molecularly distinct ?? T cell subtypes.
Academic Article Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces soluble tumor necrosis factor receptor production through tumor necrosis factor alpha-converting enzyme activation.
Academic Article Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells.
Academic Article Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.
Concept Mycobacterium Infections
Concept Mycobacterium tuberculosis
Concept Mycobacterium bovis
Academic Article Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice.
Academic Article Cell death and autophagy in tuberculosis.
Academic Article Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis.
Academic Article A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Academic Article Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype.
Academic Article NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection.
Academic Article Impaired Recognition of Mycobacterium tuberculosis by Alveolar Macrophages From Diabetic Mice.
Academic Article Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment.
Academic Article "The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report.
Academic Article Tuberculosis and lung damage: from epidemiology to pathophysiology.
Academic Article Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid.
Academic Article Empirical treatment with non-anti-tuberculosis antibiotics decreased microbiological detection in cervical tuberculous lymphadenitis.
Academic Article Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity.
Academic Article mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis.
Academic Article Tuberculosis and diabetes: from bench to bedside and back.
Academic Article Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis.
Academic Article Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits.
Academic Article Sirtuin 3 Downregulation in Mycobacterium tuberculosis-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death.
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  • Mycobacterium