Rene Maehr PhD
|Institution||University of Massachusetts Medical School|
|Department||Program in Molecular Medicine|
|Address||University of Massachusetts Medical School|
368 Plantation Street, Sherman Center, AS7.2057
Worcester MA 01605
|Institution||UMMS - School of Medicine|
|Department||RNA Therapeutics Institute|
|Institution||UMMS - Graduate School of Biomedical Sciences|
|Department||Interdisciplinary Graduate Program|
The thymus, through being a critical location for thymopoiesis, has been linked to various immune syndromes such as immunodeficiency and autoimmunity. The focus of our research program is to delineate the molecular pathways that govern thymus organogenesis and function, and to translate this knowledge to stem cell approaches to recapitulate and investigate human immune syndromes associated with this organ. In our research, we combine of variety experimental systems, including human pluripotent stem cell differentiation, CRISPR-based (epi-)genome engineering, epigenetics and functional genomics, as well as various disease models for human immune syndromes. The long-term goal is to recapitulate the disease in a patient-specific manner and to identify novel treatment strategies.
A rotation project is available
A postdoctoral position is available
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