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Caterina Strambio De Castillia PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentProgram in Molecular Medicine
AddressUMass Chan Medical School
373 Plantation Street Two Biotech Suite 114
Worcester MA 01605
Phone508-856-2383
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Molecular Medicine


    Collapse Biography 
    Collapse education and training
    University of Pavia, Pavia, PV, ItalyBSBiological Sciences
    The Rockefeller University, New York, NY, United StatesPHDCell Biology
    Collapse awards and honors
    1988Best Annual Experimental Thesis Award, Italian Society for Molecular Biology and Biophysis
    1989Fullbright Scholar Program Fellowship, Councily for the International Exchange of Scholars, United States Department of State
    1995Pre-doctoral Fellowship for Promising young Italian investigator studying abroad, Italian Foreign Ministry
    2019 - 2024Imaging Scientist Award. Project title: Bridging the gap between quantitative bioimaging and bench s, Chan Zuckerberg Initiative

    Collapse Overview 
    Collapse Summary
    Dr. Strambio-De-Castillia is an internationally recognized cell biologist and imaging scientist who specializes in developing easy-to-use and openly accessible strategies for image data management and sharing to promote scientific discovery in health and disease.
    Collapse overview

    Research interests

    Our goal is to increase the impact and efficiency of biomedical research by supporting the generation and stewardship of high-quality, reproducible, and reusable quantitative image data in compliance with the NIH Data Management and Sharing Policy. To achieve this goal, we develop and promote the use of reliable, user-friendly, easy-to-use, and, when possible, automated cyberinfrastructure and tools that assist research scientists in handling all stages of the image data life cycle from sample preparation to publication. To ensure adherence to community-developed best practices, we work in close collaboration with both national and international imaging initiatives such as BioImaging North America, Global BioImaging, the Open Microscopy Environment consortium, and QUAREP-LiMi (Quality Assessment and Reproducibility in Light Microscopy).

    For more information about available projects in the lab, please take a look at our Lab webpage.

    Collaborative projects

     

    Leadership positions

    1. Chair of the BioImaging North America Quality-Control and Data Management Working Group |
    2. Member of the QUAREP-LiMi Executive Council |
    3. Elected Member of the QUAREP-LiMi Steering Committee |
    4. Elected Co-chair of the QUAREP-LiMi Metadata Working Group (WG7) |
    5. Member of the ABRF Committee on Core Rigor and Reproducibility (CCoRRe) |
    6. Member of the NIH CFDE Ontology Working Group | 

     

    Recognitions

    The following editorials and news articles describe Dr. Strambio De Castillia's work:

    1. Spencer, S.E.W., 2022. The science of images. @umasschan magazine fall 2022 14–19.
    2. Marx, V., 2022a. The making of microscope camera standards. Nat. Methods 19, 788–791. https://doi.org/10.1038/s41592-022-01545-9
    3. Marx, V., 2022b. Imaging standards to ease reproducibility and the everyday. Nat. Methods 19, 784–788. https://doi.org/10.1038/s41592-022-01544-w
    4. Marx, V., 2021. Caterina Strambio-De-Castillia. Nat. Methods 18, 1413. https://doi.org/10.1038/s41592-021-01342-w

    5. Spencer, S.E.W., 2021. Caterina Strambio De Castillia and her team advance efforts to set microscopy data standards. UMass Chan News.

    6. Larson, L.M., 2019. Caterina Strambio De Castillia named Imaging Scientist by Chan Zuckerberg Initiative. UMass Chan News.

     

    Academic Background

    Caterina Strambio De Castillia grew up in Italy and received her Laurea in Biologia (equivalent to B.S./M.S.) from the University of Pavia in 1988. She obtained her Ph.D. (1992-1998) working with Gunter Blobel at The Rockefeller University, investigating how the nuclear pore complex interfaces with the cellular genome in yeast. She continued this work at the same institution in the laboratory of Mike Rout, initially as a postdoctoral fellow (1998-2002) and then as a Research Associate (2002-2006). She then moved to the IRB-Bellinzona and to the University of Geneva, Switzerland, where she was a staff Research Scientist (2006-2012) developing imaging and proteomics methods to study the mechanism by which HIV-1 interacts with the host defense mechanisms to gain access to the cell nucleus.  In 2012, Dr. Strambio De Castillia joined the Program in Molecular Medicine at the University of Massachusetts Medical School.

    Her work has been supported by the American Cancer Society, the European Union and the Swiss National Science Foundation, the Chan Zuckerberg Initiative, and the NIH.

    Dr. Strambio De Castillia has extensive multidisciplinary training in cellular and molecular biology, advanced microscopy, bio-image informatics, and research data management. Her work highlights the importance of open science and FAIR data principles in advancing basic biology and ensuring the sustainability and reusability of research.  

    Dr. Strambio De Castillia has a demonstrated ability to bring together individuals with diverse expertise and scientific backgrounds. She is a recognized and passionate teacher with extensive experience tailoring training to individual scientific interests, backgrounds, perspectives, and areas of origin.

    Dr. Strambio De Castillia leads several community efforts to empower collaboration at the national and international levels. She also has a recognized leading role in the community, as testified by her many leadership positions and recognitions.

     

     

     



    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cimini BA, Bankhead P, D'Antuono R, Fazeli E, Fernandez-Rodriguez J, Fuster-Barcel? C, Haase R, Jambor HK, Jones ML, Jug F, Klemm AH, Kreshuk A, Marcotti S, Martins GG, McArdle S, Miura K, Mu?oz-Barrutia A, Murphy LC, Nelson MS, N?rrelykke SF, Paul-Gilloteaux P, Pengo T, Pylv?n?inen JW, Pytowski L, Ravera A, Reinke A, Rekik Y, Strambio-De-Castillia C, Th?di? D, Uhlmann V, Umney O, Wiggins L, Eliceiri KW. The crucial role of bioimage analysts in scientific research and publication. J Cell Sci. 2024 Oct 15; 137(20). PMID: 39475207.
      Citations:    
    2. Bialy N, Alber F, Andrews B, Angelo M, Beliveau B, Bintu L, Boettiger A, Boehm U, Brown CM, Maina MB, Chambers JJ, Cimini BA, Eliceiri K, Errington R, Faklaris O, Gaudreault N, Germain RN, Goscinski W, Grunwald D, Halter M, Hanein D, Hickey JW, Lacoste J, Laude A, Lundberg E, Ma J, Malacrida L, Moore J, Nelson G, Neumann EK, Nitschke R, Onami S, Pimentel JA, Plant AL, Radtke AJ, Sabata B, Schapiro D, Sch?neberg J, Spraggins JM, Sudar D, Vierdag WAM, Volkmann N, W?hlby C, Wang SS, Yaniv Z, Strambio-De-Castillia C. Harmonizing the Generation and Pre-publication Stewardship of FAIR bioimage data. ArXiv. 2024 Aug 30. PMID: 38351940.
      Citations:    
    3. Schmied C, Nelson MS, Avilov S, Bakker GJ, Bertocchi C, Bischof J, Boehm U, Brocher J, Carvalho M, Chiritescu C, Christopher J, Cimini BA, Conde-Sousa E, Ebner M, Ecker R, Eliceiri K, Fernandez-Rodriguez J, Gaudreault N, Gelman L, Grunwald D, Gu T, Halidi N, Hammer M, Hartley M, Held M, Jug F, Kapoor V, Koksoy AA, Lacoste J, D?v?dec SL, Guyader SL, Liu P, Martins GG, Mathur A, Miura K, Montero Llopis P, Nitschke R, North A, Parslow AC, Payne-Dwyer A, Plantard L, Ali R, Schroth-Diez B, Sch?tz L, Scott RT, Seitz A, Selchow O, Sharma VP, Spitaler M, Srinivasan S, Strambio-De-Castillia C, Taatjes D, Tischer C, Jambor HK. Community-developed checklists for publishing images and image analyses. ArXiv. 2023 Sep 14. PMID: 36824427.
      Citations:    
    4. Schmied C, Nelson MS, Avilov S, Bakker GJ, Bertocchi C, Bischof J, Boehm U, Brocher J, Carvalho MT, Chiritescu C, Christopher J, Cimini BA, Conde-Sousa E, Ebner M, Ecker R, Eliceiri K, Fernandez-Rodriguez J, Gaudreault N, Gelman L, Grunwald D, Gu T, Halidi N, Hammer M, Hartley M, Held M, Jug F, Kapoor V, Koksoy AA, Lacoste J, Le D?v?dec S, Le Guyader S, Liu P, Martins GG, Mathur A, Miura K, Montero Llopis P, Nitschke R, North A, Parslow AC, Payne-Dwyer A, Plantard L, Ali R, Schroth-Diez B, Sch?tz L, Scott RT, Seitz A, Selchow O, Sharma VP, Spitaler M, Srinivasan S, Strambio-De-Castillia C, Taatjes D, Tischer C, Jambor HK. Community-developed checklists for publishing images and image analyses. Nat Methods. 2024 Feb; 21(2):170-181. PMID: 37710020.
      Citations: 2     Fields:    
    5. Lee L, Yu H, Jia BB, Jussila A, Zhu C, Chen J, Xie L, Hafner A, Mishra S, Wang DD, Strambio-De-Castillia C, Boettiger A, Ren B, Li Y, Hu M. SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data. Nat Commun. 2023 08 12; 14(1):4873. PMID: 37573342.
      Citations:    
    6. Dekker J, Alber F, Aufmkolk S, Beliveau BJ, Bruneau BG, Belmont AS, Bintu L, Boettiger A, Calandrelli R, Disteche CM, Gilbert DM, Gregor T, Hansen AS, Huang B, Huangfu D, Kalhor R, Leslie CS, Li W, Li Y, Ma J, Noble WS, Park PJ, Phillips-Cremins JE, Pollard KS, Rafelski SM, Ren B, Ruan Y, Shav-Tal Y, Shen Y, Shendure J, Shu X, Strambio-De-Castillia C, Vertii A, Zhang H, Zhong S. Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project. Mol Cell. 2023 08 03; 83(15):2624-2640. PMID: 37419111.
      Citations: 3     Fields:    Translation:Cells
    7. Wittner R, Holub P, Mascia C, Frexia F, M?ller H, Plass M, Allocca C, Betsou F, Burdett T, Cancio I, Chapman A, Chapman M, Courtot M, Curcin V, Eder J, Elliot M, Exter K, Goble C, Golebiewski M, Kisler B, Kremer A, Leo S, Lin-Gibson S, Marsano A, Mattavelli M, Moore J, Nakae H, Perseil I, Salman A, Sluka J, Soiland-Reyes S, Strambio-De-Castillia C, Sussman M, Swedlow JR, Zatloukal K, Geiger J. Toward a common standard for data and specimen provenance in life sciences. Learn Health Syst. 2024 Jan; 8(1):e10365. PMID: 38249839.
      Citations:    
    8. Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P, Brown CM, Corbett AD, Faklaris O, Lacoste J, Laude A, Nelson G, Nitschke R, Farzam F, Smith CS, Grunwald D, Strambio-De-Castillia C. Author Correction: Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model. Nat Methods. 2022 Feb; 19(2):255. PMID: 34980906.
      Citations:    Fields:    
    9. Boehm U, Nelson G, Brown CM, Bagley S, Bajcsy P, Bischof J, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Nitschke R. Author Correction: QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy. Nat Methods. 2022 Feb; 19(2):256. PMID: 34980905.
      Citations:    
    10. Rigano A, Ehmsen S, ?zt?rk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, Strambio-De-Castillia C. Author Correction: Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications. Nat Methods. 2022 Feb; 19(2):256. PMID: 34952955.
      Citations:    Fields:    
    11. Rigano A, Ehmsen S, ?zt?rk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, Strambio-De-Castillia C. Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications. Nat Methods. 2021 12; 18(12):1489-1495. PMID: 34862503.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    12. Hammer M, Huisman M, Rigano A, Boehm U, Chambers JJ, Gaudreault N, North AJ, Pimentel JA, Sudar D, Bajcsy P, Brown CM, Corbett AD, Faklaris O, Lacoste J, Laude A, Nelson G, Nitschke R, Farzam F, Smith CS, Grunwald D, Strambio-De-Castillia C. Towards community-driven metadata standards for light microscopy: tiered specifications extending the OME model. Nat Methods. 2021 12; 18(12):1427-1440. PMID: 34862501.
      Citations: 16     Fields:    Translation:HumansAnimals
    13. Ryan J, Pengo T, Rigano A, Llopis PM, Itano MS, Cameron LA, Marqu?s G, Strambio-De-Castillia C, Sanders MA, Brown CM. MethodsJ2: a software tool to capture metadata and generate comprehensive microscopy methods text. Nat Methods. 2021 12; 18(12):1414-1416. PMID: 34654919.
      Citations:    
    14. Kunis S, H?nsch S, Schmidt C, Wong F, Strambio-De-Castillia C, Weidtkamp-Peters S. MDEmic: a metadata annotation tool to facilitate management of FAIR image data in the bioimaging community. Nat Methods. 2021 12; 18(12):1416-1417. PMID: 34635849.
      Citations:    
    15. Sarkans U, Chiu W, Collinson L, Darrow MC, Ellenberg J, Grunwald D, H?rich? JK, Iudin A, Martins GG, Meehan T, Narayan K, Patwardhan A, Russell MRG, Saibil HR, Strambio-De-Castillia C, Swedlow JR, Tischer C, Uhlmann V, Verkade P, Barlow M, Bayraktar O, Birney E, Catavitello C, Cawthorne C, Wagner-Conrad S, Duke E, Paul-Gilloteaux P, Gustin E, Harkiolaki M, Kankaanp?? P, Lemberger T, McEntyre J, Moore J, Nicholls AW, Onami S, Parkinson H, Parsons M, Romanchikova M, Sofroniew N, Swoger J, Utz N, Voortman LM, Wong F, Zhang P, Kleywegt GJ, Brazma A. REMBI: Recommended Metadata for Biological Images-enabling reuse of microscopy data in biology. Nat Methods. 2021 12; 18(12):1418-1422. PMID: 34021280.
      Citations: 32     Fields:    Translation:HumansAnimals
    16. Boehm U, Nelson G, Brown CM, Bagley S, Bajcsy P, Bischof J, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Nitschke R. QUAREP-LiMi: a community endeavor to advance quality assessment and reproducibility in light microscopy. Nat Methods. 2021 12; 18(12):1423-1426. PMID: 34021279.
      Citations:    
    17. Nelson G, Boehm U, Bagley S, Bajcsy P, Bischof J, Brown CM, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Alexopoulos I, Aumayr K, Avilov S, Bakker GJ, Bammann RR, Bassi A, Beckert H, Beer S, Belyaev Y, Bierwagen J, Birngruber KA, Bosch M, Breitlow J, Cameron LA, Chalfoun J, Chambers JJ, Chen CL, Conde-Sousa E, Corbett AD, Cordelieres FP, Nery ED, Dietzel R, Eismann F, Fazeli E, Felscher A, Fried H, Gaudreault N, Goh WI, Guilbert T, Hadleigh R, Hemmerich P, Holst GA, Itano MS, Jaffe CB, Jambor HK, Jarvis SC, Keppler A, Kirchenbuechler D, Kirchner M, Kobayashi N, Krens G, Kunis S, Lacoste J, Marcello M, Martins GG, Metcalf DJ, Mitchell CA, Moore J, Mueller T, Nelson MS, Ogg S, Onami S, Palmer AL, Paul-Gilloteaux P, Pimentel JA, Plantard L, Podder S, Rexhepaj E, Royon A, Saari MA, Schapman D, Schoonderwoert V, Schroth-Diez B, Schwartz S, Shaw M, Spitaler M, Stoeckl MT, Sudar D, Teillon J, Terjung S, Thuenauer R, Wilms CD, Wright GD, Nitschke R. QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy. J Microsc. 2021 10; 284(1):56-73. PMID: 34214188.
      Citations: 18     Fields:    
    18. Luban J, Sattler RA, M?hlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res. 2021 01 15; 292:198246. PMID: 33249060.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    19. Luban J, Sattler R, M?hlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz S. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. bioRxiv. 2020 Aug 05. PMID: 32793904.
      Citations:    
    20. Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, Diehl WE, Strambio-De-Castillia C, Campbell EM, Luban J. Cyclophilin A protects HIV-1 from restriction by human TRIM5a. Nat Microbiol. 2019 12; 4(12):2044-2051. PMID: 31636416.
      Citations: 71     Fields:    Translation:HumansCells
    21. Rigano A, Galli V, Clark JM, Pereira LE, Grossi L, Luban J, Giulietti R, Leidi T, Hunter E, Valle M, Sbalzarini IF, Strambio-De-Castillia C. OMEGA: a software tool for the management, analysis, and dissemination of intracellular trafficking data that incorporates motion type classification and quality control. Available from: https://doi.org/10.1101/251850. bioRxiv.org . 2018; DOI: 10.1101/251850. View Publication.
    22. Rigano A, Galli V, Gonciarz K, Sbalzarini IF, Strambio-De-Castillia C. An algorithm-centric Monte Carlo method to empirically quantify motion-type estimation uncertainty in single-particle tracking. Available from: http://dx.doi.org/10.1101/379255. bioRxiv.org. 2018; DOI: 10.1101/379255.. View Publication.
    23. Rigano A, Strambio De Castillia C. Proposal for minimum information guidelines to report and reproduce results of particle tracking and motion analysis. Available from: https://doi.org/10.1101/155036. bioRxiv.org. 2017; DOI: 10.1101/155036. View Publication.
    24. Alghanem B, Nikitin F, Stricker T, Duchoslav E, Luban J, Strambio-De-Castillia C, Muller M, Lisacek F, Varesio E, Hopfgartner G. Optimization by infusion of multiple reaction monitoring transitions for sensitive quantification of peptides by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom. 2017 May 15; 31(9):753-761. PMID: 28199054.
      Citations:    Fields:    Translation:HumansCells
    25. Alessandro Rigano and Caterina Strambio De Castillia. Open Microscopy Environment inteGrated Analysis project: code repository. Version v20170504 (beta v034). GitHub. 2017. View Publication.
    26. Caterina Strambio De Castillia, Vanni Galli, Jasmine Clark, Andrea Danani, Raffaello Giulietti, Loris Grossi, Eric Hunter, Jeremy Luban, Massimo Maiolo, Lara E. Pereira, Alessandro Rigano, Bernd Rinn, Mario Valle . OMEGA: viral particle tracking work- and data-flows for images stored in OMERO. F1000Research 2016, 5:1560 (slides) (doi: 10.7490/f1000research.1112460.1). [Presented at 1st Annual OMERO in Action Meeting (2011)-51 slides]. 2016. View Publication.
    27. Rigano, A. & Strambio-De-Castillia, C. OMEGA: an open source environment to facilitate the analysis of intra-cellular motion, the estimation of error and the reproducibility and dissemination of analysis results. F1000Research 2016, 5:1403 (slides) (doi: 10.7490/f1000research.1112347.1). [Presented at 10th Annual OME User Meeting (2015)-12 slides]. 2016. View Publication.
    28. Alessandro Rigano, Vanni Galli, Raffaello Giulietti, Tiziano Leidi, Mario Valle, Ivo Sbalzarini, Caterina Strambio De Castillia. OMEGA: an open source environment to facilitate the execution of motion analysis workflows, to estimate error and to share results. F1000Research 2016, 5:1392 (poster) (doi:10.7490/f1000research.1112339.1). [Presented at 10th Annual OME User Meeting (2015)-poster]. 2016. View Publication.
    29. Caterina Strambio De Castillia and Alessandro Rigano. Minimum Information About Particle Tracking Experiments. Minimum Information Metadata Standard. Available at: https://biosharing.org/bsg-s000671 . 2016. View Publication.
    30. Bilbao A, Zhang Y, Varesio E, Luban J, Strambio-De-Castillia C, Lisacek F, Hopfgartner G. Ranking Fragment Ions Based on Outlier Detection for Improved Label-Free Quantification in Data-Independent Acquisition LC-MS/MS. J Proteome Res. 2015 Nov 06; 14(11):4581-93. PMID: 26412574.
      Citations: 6     Fields:    Translation:HumansCells
    31. Zhang Y, Bilbao A, Bruderer T, Luban J, Strambio-De-Castillia C, Lisacek F, Hopfgartner G, Varesio E. The Use of Variable Q1 Isolation Windows Improves Selectivity in LC-SWATH-MS Acquisition. J Proteome Res. 2015 Oct 02; 14(10):4359-71. PMID: 26302369.
      Citations: 54     Fields:    Translation:HumansCells
    32. Zhang Y, Bottinelli D, Lisacek F, Luban J, Strambio-De-Castillia C, Varesio E, Hopfgartner G. Optimization of human dendritic cell sample preparation for mass spectrometry-based proteomic studies. Anal Biochem. 2015 Sep 01; 484:40-50. PMID: 25983236.
      Citations: 8     Fields:    Translation:HumansCells
    33. Bilbao A, Varesio E, Luban J, Strambio-De-Castillia C, Hopfgartner G, M?ller M, Lisacek F. Processing strategies and software solutions for data-independent acquisition in mass spectrometry. Proteomics. 2015 Mar; 15(5-6):964-80. PMID: 25430050.
      Citations: 60     Fields:    
    34. Niepel M, Molloy KR, Williams R, Farr JC, Meinema AC, Vecchietti N, Cristea IM, Chait BT, Rout MP, Strambio-De-Castillia C. The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome. Mol Biol Cell. 2013 Dec; 24(24):3920-38. PMID: 24152732.
      Citations: 66     Fields:    Translation:AnimalsCells
    35. Xu H, Franks T, Gibson G, Huber K, Rahm N, Strambio De Castillia C, Luban J, Aiken C, Watkins S, Sluis-Cremer N, Ambrose Z. Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology. 2013 Jul 09; 10:70. PMID: 23835323.
      Citations: 55     Fields:    Translation:HumansCells
    36. Strambio-De-Castilla C. Jumping over the fence: RNA nuclear export revisited. Nucleus. 2013 Mar-Apr; 4(2):95-9. PMID: 23528257.
      Citations: 3     Fields:    Translation:HumansCells
    37. Vecchietti, N., N. Storelli, S. Peduzzi, P. Barbieri, C. Strambio-de-Castillia, and M. Tonolla. Gli aggregati sintrofici di Thiodictyon syntrophicum CAD16 e Desulfocapsa thiozymogenes CAD626 del lago di Cadagno. Bollettino della Societa' Ticinese di Scienze Naturali. 2012; 100:107 - 119. View Publication.
    38. Tarkowski M, Ferraris L, Martone S, Strambio de Castillia F, Misciagna D, Mazzucchelli RI, Lattuada E, Paraninfo G, Galli M, Riva A. Expression of interleukin-15 and interleukin-15Ra in monocytes of HIV type 1-infected patients with different courses of disease progression. AIDS Res Hum Retroviruses. 2012 Jul; 28(7):693-701. PMID: 21902580.
      Citations: 8     Fields:    Translation:HumansCells
    39. Pertel T, Hausmann S, Morger D, Z?ger S, Guerra J, Lascano J, Reinhard C, Santoni FA, Uchil PD, Chatel L, Bisiaux A, Albert ML, Strambio-De-Castillia C, Mothes W, Pizzato M, Gr?tter MG, Luban J. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature. 2011 Apr 21; 472(7343):361-5. PMID: 21512573.
      Citations: 359     Fields:    Translation:HumansCells
    40. Strambio-De-Castillia C, Niepel M, Rout MP. The nuclear pore complex: bridging nuclear transport and gene regulation. Nat Rev Mol Cell Biol. 2010 Jul; 11(7):490-501. PMID: 20571586.
      Citations: 266     Fields:    Translation:HumansAnimalsCells
    41. Sokolskaja E, Olivari S, Zufferey M, Strambio-De-Castillia C, Pizzato M, Luban J. Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions. J Virol. 2010 May; 84(9):4851-5. PMID: 20181694.
      Citations: 8     Fields:    Translation:HumansCells
    42. Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Gr?tter C, Martinetti G, Mazzucchelli L, Gr?tter M, Manz MG, Luban J. Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest. 2009 Oct; 119(10):3035-47. PMID: 19741300.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    43. Sebastian S, Gr?tter C, Strambio de Castillia C, Pertel T, Olivari S, Gr?tter MG, Luban J. An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding. J Virol. 2009 Apr; 83(7):3365-73. PMID: 19153241.
      Citations: 20     Fields:    Translation:HumansCells
    44. Strambio-de-Castillia C, Tetenbaum-Novatt J, Imai BS, Chait BT, Rout MP. A method for the rapid and efficient elution of native affinity-purified protein A tagged complexes. J Proteome Res. 2005 Nov-Dec; 4(6):2250-6. PMID: 16335973.
      Citations: 10     Fields:    Translation:Cells
    45. Niepel M, Strambio-de-Castillia C, Fasolo J, Chait BT, Rout MP. The nuclear pore complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly. J Cell Biol. 2005 Jul 18; 170(2):225-35. PMID: 16027220.
      Citations: 59     Fields:    Translation:AnimalsCells
    46. Kipper J, Strambio-de-Castillia C, Suprapto A, Rout MP. Isolation of nuclear envelope from Saccharomyces cerevisiae. Methods Enzymol. 2002; 351:394-408. PMID: 12073359.
      Citations: 6     Fields:    Translation:AnimalsCells
    47. Strambio-de-Castillia C, Rout MP. The structure and composition of the yeast NPC. Results Probl Cell Differ. 2002; 35:1-23. PMID: 11791402.
      Citations: 1     Fields:    Translation:AnimalsCells
    48. Rout M.P. and C. Strambio-De-Castillia. Isolation of Yeast Nuclear Pore Complex and Nuclear Envelopes. INSERM Atelier de Formation/INSERM Worshops. 2000; 121:23-24.
    49. Strambio de Castillia C, Rout MP. TAPping into transport. Nat Cell Biol. 1999 Jun; 1(2):E31-3. PMID: 10559889.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    50. Strambio-de-Castillia C, Blobel G, Rout MP. Proteins connecting the nuclear pore complex with the nuclear interior. J Cell Biol. 1999 Mar 08; 144(5):839-55. PMID: 10085285.
      Citations: 103     Fields:    Translation:AnimalsCells
    51. Hurwitz ME, Strambio-de-Castillia C, Blobel G. Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex. Proc Natl Acad Sci U S A. 1998 Sep 15; 95(19):11241-5. PMID: 9736720.
      Citations: 26     Fields:    Translation:Cells
    52. Strambio-De-Castillia C. Identification and characterization of Mlp1p and Mlp2p: Molecular components of filaments localized at the interface between the nuclear pore complex and the nuclear interior. Ph.D. Thesis dissertation. The Rockefeller University, New York, NY, USA. 1998.
    53. Rout M.P. and C. Strambio-De-Castillia. Isolation of Yeast Nuclear Pore Complex and Nuclear Envelopes. Cell Biology a Laboratory Handbook, J. E. Celis. 1998; 2:143-151.
    54. Strambio-de-Castillia C, Blobel G, Rout MP. Isolation and characterization of nuclear envelopes from the yeast Saccharomyces. J Cell Biol. 1995 Oct; 131(1):19-31. PMID: 7559775.
      Citations: 40     Fields:    Translation:AnimalsCells
    55. Kraemer DM, Strambio-de-Castillia C, Blobel G, Rout MP. The essential yeast nucleoporin NUP159 is located on the cytoplasmic side of the nuclear pore complex and serves in karyopherin-mediated binding of transport substrate. J Biol Chem. 1995 Aug 11; 270(32):19017-21. PMID: 7642562.
      Citations: 64     Fields:    Translation:AnimalsCells
    56. Strambio-de-Castillia C, Hunter E. Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis. J Virol. 1992 Dec; 66(12):7021-32. PMID: 1279197.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    57. Strambio-De-Castillia C. Presence of Transcriptional Elements in Putative Human Replication Origins. Doctoral thesis dissertation. Universita' degli Studi di Pavia, Pavia, Italy. 1988.
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