"CDC2-CDC28 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CEREVISIAE; and the CDC2 PROTEIN KINASE found in mammalian species.
| Descriptor ID |
D042846
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500 D12.644.360.250.067 D12.776.167.200.067 D12.776.476.250.067
|
| Concept/Terms |
CDC2-CDC28 Kinases- CDC2-CDC28 Kinases
- CDC2 CDC28 Kinases
- CDC2+-CDC28-related Protein Kinase
- CDC2+ CDC28 related Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "CDC2-CDC28 Kinases".
Below are MeSH descriptors whose meaning is more specific than "CDC2-CDC28 Kinases".
This graph shows the total number of publications written about "CDC2-CDC28 Kinases" by people in this website by year, and whether "CDC2-CDC28 Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "CDC2-CDC28 Kinases" by people in Profiles.
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Medina R, van der Deen M, Miele-Chamberland A, Xie RL, van Wijnen AJ, Stein JL, Stein GS. The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes. Cancer Res. 2007 Nov 01; 67(21):10334-42.
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Miele A, Braastad CD, Holmes WF, Mitra P, Medina R, Xie R, Zaidi SK, Ye X, Wei Y, Harper JW, van Wijnen AJ, Stein JL, Stein GS. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol. 2005 Jul; 25(14):6140-53.
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Xie RL, Gupta S, Miele A, Shiffman D, Stein JL, Stein GS, van Wijnen AJ. The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter. J Biol Chem. 2003 Jul 18; 278(29):26589-96.
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Hinchcliffe EH, Sluder G. Two for two: Cdk2 and its role in centrosome doubling. Oncogene. 2002 Sep 09; 21(40):6154-60.
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Hinchcliffe EH, Sluder G. Centrosome duplication: three kinases come up a winner! Curr Biol. 2001 Sep 04; 11(17):R698-701.
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Lane ME, Elend M, Heidmann D, Herr A, Marzodko S, Herzig A, Lehner CF. A screen for modifiers of cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2. Genetics. 2000 May; 155(1):233-44.
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Hinchcliffe EH, Li C, Thompson EA, Maller JL, Sluder G. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. Science. 1999 Feb 05; 283(5403):851-4.
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Lane ME, Sauer K, Wallace K, Jan YN, Lehner CF, Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 1996 Dec 27; 87(7):1225-35.