"Genes, erbB-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
| Descriptor ID |
D018734
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.295.305
|
| Concept/Terms |
Genes, erbB-2- Genes, erbB-2
- c-erbB-2 Genes
- c erbB 2 Genes
- c-erbB-2 Gene
- Genes, erbb2
- Gene, erbb2
- erbb2 Gene
- erbb2 Genes
- Genes, HER-2
- HER-2 Gene
- HER-2 Genes
- Genes, neu
- neu Gene
- neu Genes
- Genes, HER2
- Gene, HER2
- HER2 Gene
- HER2 Genes
- erbB-2 Genes
- erbB 2 Genes
- erbB-2 Gene
- c-erbB-2 Proto-Oncogenes
- c erbB 2 Proto Oncogenes
- c-erbB-2 Proto-Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, erbB-2".
Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-2".
This graph shows the total number of publications written about "Genes, erbB-2" by people in this website by year, and whether "Genes, erbB-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genes, erbB-2" by people in Profiles.
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Fischer AH, Schwartz MR, Moriarty AT, Wilbur DC, Souers R, Fatheree L, Booth CN, Clayton AC, Kurtyz DF, Padmanabhan V, Crothers BA. Immunohistochemistry practices of cytopathology laboratories: a survey of participants in the College of American Pathologists Nongynecologic Cytopathology Education Program. Arch Pathol Lab Med. 2014 Sep; 138(9):1167-72.
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Ithimakin S, Day KC, Malik F, Zen Q, Dawsey SJ, Bersano-Begey TF, Quraishi AA, Ignatoski KW, Daignault S, Davis A, Hall CL, Palanisamy N, Heath AN, Tawakkol N, Luther TK, Clouthier SG, Chadwick WA, Day ML, Kleer CG, Thomas DG, Hayes DF, Korkaya H, Wicha MS. HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab. Cancer Res. 2013 Mar 01; 73(5):1635-46.
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Liu X, Nakamura K, Cheng D, Peng C, Xiao N, Liu Y, Chen L, Rusckowski M, Hnatowich DJ. Her2/neu small interfering RNA delivered in culture by a streptavidin nanoparticle. Curr Drug Deliv. 2012 Jul; 9(4):431-6.
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Reid A, Vidal L, Shaw H, de Bono J. Dual inhibition of ErbB1 (EGFR/HER1) and ErbB2 (HER2/neu). Eur J Cancer. 2007 Feb; 43(3):481-9.
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Swisher EM, Gown AM, Skelly M, Ek M, Tamimi HK, Cain JM, Greer BE, Muntz HG, Goff BA. The expression of epidermal growth factor receptor, HER-2/Neu, p53, and Ki-67 antigen in uterine malignant mixed mesodermal tumors and adenosarcoma. Gynecol Oncol. 1996 Jan; 60(1):81-8.
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Crane PD, Onthank DC, Bourque CR, Heminway SJ, Mazaika TJ, Leav I, Zambuto GF, Lazewatsky JL, Villamil-Perez L, Carroll TR. Autoradiography and radioscintigraphy of technetium-99m-sestamibi in c-neu transgenic mice. J Nucl Med. 1995 Oct; 36(10):1862-8.